Conservation of cofitness between PP_2327 and PP_1988 in Pseudomonas putida KT2440

70 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_2327 transcriptional dual regulator / CysB-O-acetyl-L-serine 1.0 PP_1988 3-isopropylmalate dehydrogenase 0.82 11
Pseudomonas fluorescens FW300-N2C3 0.97 AO356_03180 CysB family transcriptional regulator 0.94 AO356_21415 3-isopropylmalate dehydrogenase 0.48 35
Pseudomonas fluorescens FW300-N2E2 0.97 Pf6N2E2_2465 Cys regulon transcriptional activator CysB 0.94 Pf6N2E2_66 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.77 3
Pseudomonas fluorescens FW300-N2E3 0.97 AO353_19060 CysB family transcriptional regulator 0.92 AO353_20635 3-isopropylmalate dehydrogenase 0.64 20
Pseudomonas fluorescens GW456-L13 0.97 PfGW456L13_2230 Cys regulon transcriptional activator CysB 0.93 PfGW456L13_3945 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.88 14
Pseudomonas fluorescens FW300-N1B4 0.96 Pf1N1B4_283 Cys regulon transcriptional activator CysB 0.93 Pf1N1B4_12 3-isopropylmalate dehydrogenase (EC 1.1.1.85) — —
Pseudomonas sp. RS175 0.96 PFR28_00966 HTH-type transcriptional regulator CysB 0.93 PFR28_02821 3-isopropylmalate dehydrogenase low > 88
Pseudomonas fluorescens SBW25 0.96 PFLU_RS08410 HTH-type transcriptional regulator CysB 0.93 PFLU_RS20565 3-isopropylmalate dehydrogenase low > 109
Pseudomonas fluorescens SBW25-INTG 0.96 PFLU_RS08410 HTH-type transcriptional regulator CysB 0.93 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.39 27
Pseudomonas simiae WCS417 0.96 PS417_08460 CysB family transcriptional regulator 0.93 PS417_18585 3-isopropylmalate dehydrogenase — —
Pseudomonas sp. S08-1 0.93 OH686_01730 Cys regulon transcriptional activator CysB 0.87 OH686_04470 3-isopropylmalate dehydrogenase low > 80
Pseudomonas syringae pv. syringae B728a ΔmexB 0.93 Psyr_2077 regulatory protein, LysR:LysR, substrate-binding protein 0.91 Psyr_1985 3-isopropylmalate dehydrogenase 0.70 25
Pseudomonas syringae pv. syringae B728a 0.93 Psyr_2077 regulatory protein, LysR:LysR, substrate-binding protein 0.91 Psyr_1985 3-isopropylmalate dehydrogenase 0.78 24
Pseudomonas stutzeri RCH2 0.91 Psest_2329 Transcriptional regulator 0.87 Psest_2589 3-isopropylmalate dehydrogenase 0.70 20
Marinobacter adhaerens HP15 0.80 HP15_1854 transcriptional regulator, LysR family 0.73 HP15_1832 3-isopropylmalate dehydrogenase — —
Vibrio cholerae E7946 ATCC 55056 0.70 CSW01_09545 HTH-type transcriptional regulator CysB 0.53 CSW01_12600 3-isopropylmalate dehydrogenase — —
Dickeya dianthicola 67-19 0.69 HGI48_RS10540 HTH-type transcriptional regulator CysB 0.52 HGI48_RS18060 3-isopropylmalate dehydrogenase low > 71
Dickeya dadantii 3937 0.68 DDA3937_RS10540 HTH-type transcriptional regulator CysB 0.52 DDA3937_RS18120 3-isopropylmalate dehydrogenase low > 74
Alteromonas macleodii MIT1002 0.68 MIT1002_02005 Cys regulon transcriptional activator 0.51 MIT1002_00948 3-isopropylmalate dehydrogenase — —
Dickeya dianthicola ME23 0.68 DZA65_RS11020 HTH-type transcriptional regulator CysB 0.52 DZA65_RS19205 3-isopropylmalate dehydrogenase 0.62 37
Rahnella sp. WP5 0.68 EX31_RS09890 HTH-type transcriptional regulator CysB 0.53 EX31_RS03685 3-isopropylmalate dehydrogenase 0.96 21
Pectobacterium carotovorum WPP14 0.68 HER17_RS10870 HTH-type transcriptional regulator CysB 0.52 HER17_RS03080 3-isopropylmalate dehydrogenase 0.94 20
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.68 GFF2712 Cys regulon transcriptional activator CysB 0.54 GFF165 3-isopropylmalate dehydrogenase (EC 1.1.1.85) — —
Serratia liquefaciens MT49 0.68 IAI46_13965 HTH-type transcriptional regulator CysB 0.53 IAI46_03350 3-isopropylmalate dehydrogenase — —
Pantoea sp. MT58 0.67 IAI47_09240 HTH-type transcriptional regulator CysB 0.50 IAI47_16005 3-isopropylmalate dehydrogenase 0.69 27
Enterobacter sp. TBS_079 0.67 MPMX20_02501 HTH-type transcriptional regulator CysB 0.54 MPMX20_00768 3-isopropylmalate dehydrogenase — —
Enterobacter asburiae PDN3 0.67 EX28DRAFT_0946 Transcriptional regulator 0.54 EX28DRAFT_3669 3-isopropylmalate dehydrogenase — —
Klebsiella michiganensis M5al 0.67 BWI76_RS11930 LysR family transcriptional regulator CysB 0.53 BWI76_RS04675 3-isopropylmalate dehydrogenase — —
Escherichia coli ECOR38 0.67 HEPCGN_25600 cysB HTH-type transcriptional regulator CysB 0.54 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase — —
Erwinia tracheiphila SCR3 0.67 LU632_RS12550 cysB HTH-type transcriptional regulator CysB 0.50 LU632_RS02875 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.67 OHPLBJKB_02409 HTH-type transcriptional regulator CysB 0.54 OHPLBJKB_03584 3-isopropylmalate dehydrogenase low > 73
Escherichia coli ECRC98 0.67 JDDGAC_05145 cysB HTH-type transcriptional regulator CysB 0.54 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC101 0.67 MCAODC_15665 cysB HTH-type transcriptional regulator CysB 0.54 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase — —
Escherichia fergusonii Becca 0.67 EFB2_02652 HTH-type transcriptional regulator CysB 0.54 EFB2_03972 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC102 0.67 NIAGMN_26770 cysB HTH-type transcriptional regulator CysB 0.54 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC101 0.67 OKFHMN_02600 cysB HTH-type transcriptional regulator CysB 0.54 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli BW25113 0.67 b1275 cysB DNA-binding transcriptional dual regulator, O-acetyl-L-serine-binding (NCBI) 0.54 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) — —
Escherichia coli ECOR27 0.67 NOLOHH_20265 cysB HTH-type transcriptional regulator CysB 0.54 NOLOHH_03065 leuA 2-isopropylmalate synthase — —
Escherichia coli Nissle 1917 0.67 ECOLIN_RS07680 HTH-type transcriptional regulator CysB 0.54 ECOLIN_RS00395 3-isopropylmalate dehydrogenase low > 52
Escherichia coli ECRC99 0.67 KEDOAH_26165 cysB HTH-type transcriptional regulator CysB 0.54 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli BL21 0.67 ECD_01251 N-acetylserine-responsive cysteine regulon transcriptional activator; autorepressor 0.54 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent — —
Escherichia coli ECRC62 0.67 BNILDI_18415 cysB HTH-type transcriptional regulator CysB 0.54 BNILDI_08545 leuA 2-isopropylmalate synthase — —
Shewanella amazonensis SB2B 0.66 Sama_1324 cysB transcriptional regulator CysB (RefSeq) 0.52 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) — —
Shewanella oneidensis MR-1 0.66 SO2649 cysB cys regulon transcriptional activator (NCBI ptt file) 0.53 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.84 23
Shewanella loihica PV-4 0.66 Shew_1624 cysB transcriptional regulator CysB (RefSeq) 0.53 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) — —
Shewanella sp. ANA-3 0.65 Shewana3_1731 cysB transcriptional regulator CysB (RefSeq) 0.53 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) — —
Dechlorosoma suillum PS 0.52 Dsui_1988 transcriptional regulator 0.68 Dsui_3198 3-isopropylmalate dehydrogenase — —
Paraburkholderia graminis OAS925 0.49 ABIE53_001994 LysR family cys regulon transcriptional activator 0.65 ABIE53_004804 3-isopropylmalate dehydrogenase low > 113
Paraburkholderia bryophila 376MFSha3.1 0.49 H281DRAFT_00782 transcriptional regulator, LysR family 0.65 H281DRAFT_06072 3-isopropylmalate dehydrogenase low > 103
Burkholderia phytofirmans PsJN 0.49 BPHYT_RS08810 CysB family transcriptional regulator 0.64 BPHYT_RS33900 3-isopropylmalate dehydrogenase low > 109
Paraburkholderia sabiae LMG 24235 0.48 QEN71_RS22570 CysB family HTH-type transcriptional regulator 0.63 QEN71_RS17620 3-isopropylmalate dehydrogenase low > 153
Hydrogenophaga sp. GW460-11-11-14-LB1 0.48 GFF5044 Alkanesulfonate utilization operon LysR-family regulator CbI 0.63 GFF3360 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 90
Variovorax sp. SCN45 0.47 GFF3358 Alkanesulfonate utilization operon LysR-family regulator Cbl 0.64 GFF3888 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 127
Ralstonia sp. UNC404CL21Col 0.47 ABZR87_RS11555 CysB family HTH-type transcriptional regulator 0.65 ABZR87_RS14530 3-isopropylmalate dehydrogenase 0.35 40
Herbaspirillum seropedicae SmR1 0.47 HSERO_RS08245 CysB family transcriptional regulator 0.65 HSERO_RS16500 3-isopropylmalate dehydrogenase low > 78
Ralstonia solanacearum IBSBF1503 0.46 RALBFv3_RS00100 CysB family HTH-type transcriptional regulator 0.64 RALBFv3_RS02610 3-isopropylmalate dehydrogenase low > 76
Ralstonia solanacearum PSI07 0.46 RPSI07_RS17385 CysB family HTH-type transcriptional regulator 0.63 RPSI07_RS14705 3-isopropylmalate dehydrogenase low > 81
Ralstonia solanacearum UW163 0.46 UW163_RS13430 CysB family HTH-type transcriptional regulator 0.64 UW163_RS11115 3-isopropylmalate dehydrogenase — —
Ralstonia solanacearum GMI1000 0.46 RS_RS06760 CysB family HTH-type transcriptional regulator 0.64 RS_RS09990 3-isopropylmalate dehydrogenase low > 80
Variovorax sp. OAS795 0.46 ABID97_RS02980 CysB family HTH-type transcriptional regulator 0.64 ABID97_RS08455 3-isopropylmalate dehydrogenase — —
Cupriavidus basilensis FW507-4G11 0.45 RR42_RS12245 transcriptional regulator 0.64 RR42_RS14385 3-isopropylmalate dehydrogenase low > 128
Acidovorax sp. GW101-3H11 0.44 Ac3H11_2403 Alkanesulfonate utilization operon LysR-family regulator CbI 0.64 Ac3H11_1528 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.62 44
Kangiella aquimarina DSM 16071 0.43 B158DRAFT_2455 Transcriptional regulator 0.70 B158DRAFT_1322 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 40
Acinetobacter radioresistens SK82 0.40 MPMX26_02171 HTH-type transcriptional regulator SsuR 0.73 MPMX26_00348 3-isopropylmalate dehydrogenase 0.91 9
Castellaniella sp019104865 MT123 0.37 ABCV34_RS08230 CysB family HTH-type transcriptional regulator 0.63 ABCV34_RS04280 3-isopropylmalate dehydrogenase low > 48
Dyella japonica UNC79MFTsu3.2 0.37 ABZR86_RS05885 LysR substrate-binding domain-containing protein 0.42 ABZR86_RS15950 3-isopropylmalate dehydrogenase 0.97 12
Rhodanobacter sp. FW510-T8 0.37 OKGIIK_05975 lysR CysB family transcriptional regulator 0.45 OKGIIK_13595 leuB 3-isopropylmalate dehydrogenase low > 52
Rhodanobacter denitrificans MT42 0.35 LRK55_RS00690 LysR substrate-binding domain-containing protein 0.45 LRK55_RS09965 3-isopropylmalate dehydrogenase low > 63
Rhodanobacter denitrificans FW104-10B01 0.35 LRK54_RS00915 LysR substrate-binding domain-containing protein 0.45 LRK54_RS10325 3-isopropylmalate dehydrogenase 0.72 12
Lysobacter sp. OAE881 0.34 ABIE51_RS15850 LysR family transcriptional regulator 0.49 ABIE51_RS17585 3-isopropylmalate dehydrogenase 0.97 20
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.1249.1 Transcriptional regulator 0.81 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 74

Not shown: 0 genomes with orthologs for PP_2327 only; 32 genomes with orthologs for PP_1988 only