Conservation of cofitness between PP_2160 and PP_1527 in Pseudomonas putida KT2440

70 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_2160 NADPH-dependent 7-cyano-7-deazaguanine reductase 1.0 PP_1527 tRNA threonylcarbamoyladenosine dehydratase (t(6)A37 dehydratase) 0.36 14
Pseudomonas fluorescens GW456-L13 0.82 PfGW456L13_4015 NADPH dependent preQ0 reductase (EC 1.7.1.13) 0.81 PfGW456L13_4719 HesA/MoeB/ThiF family protein related to EC-YgdL low > 87
Pseudomonas fluorescens FW300-N1B4 0.82 Pf1N1B4_65 NADPH dependent preQ0 reductase (EC 1.7.1.13) 0.81 Pf1N1B4_3074 HesA/MoeB/ThiF family protein related to EC-YgdL low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.82 Psyr_1907 GTP cyclohydrolase I 0.77 Psyr_1333 UBA/THIF-type NAD/FAD binding fold protein — —
Pseudomonas syringae pv. syringae B728a 0.82 Psyr_1907 GTP cyclohydrolase I 0.77 Psyr_1333 UBA/THIF-type NAD/FAD binding fold protein low > 86
Pseudomonas fluorescens FW300-N2E3 0.82 AO353_00345 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.81 AO353_16420 thiamine biosynthesis protein ThiF low > 101
Pseudomonas fluorescens SBW25-INTG 0.81 PFLU_RS07770 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.82 PFLU_RS06230 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 109
Pseudomonas fluorescens SBW25 0.81 PFLU_RS07770 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.82 PFLU_RS06230 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 109
Pseudomonas simiae WCS417 0.81 PS417_07695 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.81 PS417_06165 thiamine biosynthesis protein ThiF low > 88
Pseudomonas sp. RS175 0.81 PFR28_01136 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.81 PFR28_00387 tRNA threonylcarbamoyladenosine dehydratase low > 88
Pseudomonas fluorescens FW300-N2E2 0.80 Pf6N2E2_2264 NADPH dependent preQ0 reductase (EC 1.7.1.13) 0.81 Pf6N2E2_3081 HesA/MoeB/ThiF family protein related to EC-YgdL 0.25 68
Pseudomonas fluorescens FW300-N2C3 0.80 AO356_02205 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.81 AO356_06085 thiamine biosynthesis protein ThiF low > 104
Pseudomonas stutzeri RCH2 0.78 Psest_2714 7-cyano-7-deazaguanine reductase 0.76 Psest_1619 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 low > 67
Pseudomonas sp. S08-1 0.75 OH686_22700 queuine synthase 0.75 OH686_06545 HesA/MoeB/ThiF family protein low > 80
Rhodanobacter sp. FW510-T8 0.54 OKGIIK_13395 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.44 OKGIIK_03630 tcdA tRNA A37 threonylcarbamoyladenosine dehydratase low > 52
Rhodanobacter denitrificans MT42 0.53 LRK55_RS10150 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.46 LRK55_RS14520 tRNA threonylcarbamoyladenosine dehydratase low > 63
Rhodanobacter denitrificans FW104-10B01 0.53 LRK54_RS10510 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.46 LRK54_RS14805 tRNA threonylcarbamoyladenosine dehydratase low > 59
Dechlorosoma suillum PS 0.53 Dsui_0505 7-cyano-7-deazaguanine reductase 0.40 Dsui_1346 dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis low > 51
Dyella japonica UNC79MFTsu3.2 0.52 ABZR86_RS16195 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.48 ABZR86_RS00565 ThiF family adenylyltransferase low > 74
Ralstonia solanacearum PSI07 0.50 RPSI07_RS21815 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.38 RPSI07_RS20115 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 81
Vibrio cholerae E7946 ATCC 55056 0.50 CSW01_04620 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.54 CSW01_11750 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 62
Ralstonia solanacearum GMI1000 0.50 RS_RS02220 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.42 RS_RS03895 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 80
Ralstonia solanacearum IBSBF1503 0.50 RALBFv3_RS11390 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.39 RALBFv3_RS13100 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 76
Ralstonia solanacearum UW163 0.50 UW163_RS02195 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.39 UW163_RS00465 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA — —
Serratia liquefaciens MT49 0.50 IAI46_21580 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.56 IAI46_20360 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 86
Shewanella loihica PV-4 0.49 Shew_2654 queF 7-cyano-7-deazaguanine reductase (RefSeq) 0.54 Shew_3251 UBA/THIF-type NAD/FAD binding protein (RefSeq) low > 60
Rahnella sp. WP5 0.49 EX31_RS13085 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.55 EX31_RS13130 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 89
Cupriavidus basilensis FW507-4G11 0.49 RR42_RS02310 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.42 RR42_RS15305 heme biosynthesis protein HemY low > 128
Escherichia coli ECRC101 0.49 OKFHMN_20190 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.55 OKFHMN_20095 tcdA tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA — —
Escherichia coli ECRC101 0.49 MCAODC_10715 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.55 MCAODC_10620 tcdA tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA — —
Escherichia coli ECRC99 0.49 KEDOAH_07940 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.55 KEDOAH_08035 tcdA tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA — —
Escherichia coli ECRC102 0.49 NIAGMN_17960 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.55 NIAGMN_17865 tcdA tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA — —
Escherichia coli ECRC98 0.49 JDDGAC_23855 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.55 JDDGAC_23760 tcdA tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA — —
Escherichia coli Nissle 1917 0.49 ECOLIN_RS15580 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.56 ECOLIN_RS15670 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 52
Escherichia fergusonii Becca 0.49 EFB2_01123 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.56 EFB2_01105 tRNA threonylcarbamoyladenosine dehydratase low > 86
Escherichia coli ECOR38 0.49 HEPCGN_19445 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.56 HEPCGN_19350 tcdA tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 85
Escherichia coli ECOR27 0.49 NOLOHH_12070 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.56 NOLOHH_11975 tcdA tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 57
Ralstonia sp. UNC404CL21Col 0.49 ABZR87_RS07355 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.43 ABZR87_RS09175 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 80
Escherichia coli ECRC62 0.49 BNILDI_10575 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.56 BNILDI_10480 tcdA tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA — —
Escherichia coli BL21 0.49 ECD_02639 7-cyano-7-deazaguanine reductase (NADPH-dependent) 0.56 ECD_02663 tRNA threonylcarbamoyladenosine dehydratase; sulfur acceptor for CsdA low > 60
Escherichia coli HS(pFamp)R (ATCC 700891) 0.49 OHPLBJKB_00937 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.56 OHPLBJKB_00919 tRNA threonylcarbamoyladenosine dehydratase low > 73
Escherichia coli BW25113 0.48 b2794 yqcD hypothetical protein (NCBI) 0.56 b2812 ygdL hypothetical protein (NCBI) low > 76
Shewanella oneidensis MR-1 0.48 SO1608 conserved hypothetical protein (NCBI ptt file) 0.54 SO3895 HesA/MoeB/ThiF family protein (NCBI ptt file) low > 76
Enterobacter asburiae PDN3 0.48 EX28DRAFT_2876 7-cyano-7-deazaguanine reductase 0.54 EX28DRAFT_2888 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.48 GFF4849 NADPH dependent preQ0 reductase (EC 1.7.1.13) 0.56 GFF4870 CsdL (EC-YgdL) protein of the HesA/MoeB/ThiF family, part of the CsdA-E-L sulfur transfer pathway low > 78
Shewanella sp. ANA-3 0.48 Shewana3_2835 queF 7-cyano-7-deazaguanine reductase (RefSeq) 0.56 Shewana3_0735 UBA/THIF-type NAD/FAD binding protein (RefSeq) low > 73
Enterobacter sp. TBS_079 0.48 MPMX20_03664 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.54 MPMX20_03675 tRNA threonylcarbamoyladenosine dehydratase low > 85
Pantoea sp. MT58 0.48 IAI47_04050 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.56 IAI47_04005 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 76
Erwinia tracheiphila SCR3 0.47 LU632_RS06280 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.56 LU632_RS06230 tcdA tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 74
Klebsiella michiganensis M5al 0.47 BWI76_RS22865 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.53 BWI76_RS22975 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 92
Hydrogenophaga sp. GW460-11-11-14-LB1 0.47 GFF722 NADPH dependent preQ0 reductase (EC 1.7.1.13) 0.30 GFF4538 Probable HesA/MoeB/ThiF family protein low > 90
Paraburkholderia sabiae LMG 24235 0.47 QEN71_RS01975 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.42 QEN71_RS02715 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 153
Shewanella amazonensis SB2B 0.47 Sama_1120 queF 7-cyano-7-deazaguanine reductase (RefSeq) 0.57 Sama_0546 HesA/MoeB/ThiF family protein (RefSeq) low > 62
Dickeya dadantii 3937 0.47 DDA3937_RS04655 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.55 DDA3937_RS05030 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 74
Burkholderia phytofirmans PsJN 0.46 BPHYT_RS03135 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.44 BPHYT_RS15990 heme biosynthesis protein HemY low > 109
Paraburkholderia bryophila 376MFSha3.1 0.46 H281DRAFT_01889 7-cyano-7-deazaguanine reductase 0.44 H281DRAFT_04134 tRNA A37 threonylcarbamoyladenosine dehydratase low > 103
Dickeya dianthicola 67-19 0.46 HGI48_RS04615 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.54 HGI48_RS05035 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 71
Paraburkholderia graminis OAS925 0.46 ABIE53_000759 7-cyano-7-deazaguanine reductase 0.45 ABIE53_003371 tRNA A37 threonylcarbamoyladenosine dehydratase low > 113
Dickeya dianthicola ME23 0.46 DZA65_RS04535 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.54 DZA65_RS05375 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 75
Pectobacterium carotovorum WPP14 0.46 HER17_RS16390 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.56 HER17_RS16435 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA low > 75
Herbaspirillum seropedicae SmR1 0.45 HSERO_RS19515 7-cyano-7-deazaguanine reductase 0.40 HSERO_RS06230 heme biosynthesis protein HemY low > 78
Kangiella aquimarina DSM 16071 0.45 B158DRAFT_2159 7-cyano-7-deazaguanine reductase 0.44 B158DRAFT_0922 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 low > 40
Acidovorax sp. GW101-3H11 0.45 Ac3H11_1595 NADPH dependent preQ0 reductase (EC 1.7.1.13) 0.36 Ac3H11_2482 Probable HesA/MoeB/ThiF family protein low > 79
Variovorax sp. SCN45 0.45 GFF6017 NADPH-dependent 7-cyano-7-deazaguanine reductase (EC 1.7.1.13) 0.29 GFF289 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 low > 127
Xanthomonas campestris pv. campestris strain 8004 0.44 Xcc-8004.4789.1 NADPH dependent preQ0 reductase (EC 1.7.1.13) 0.40 Xcc-8004.3494.1 Molybdopterin biosynthesis protein MoeB low > 74
Lysobacter sp. OAE881 0.44 ABIE51_RS00515 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.45 ABIE51_RS12585 tRNA threonylcarbamoyladenosine dehydratase low > 62
Alteromonas macleodii MIT1002 0.44 MIT1002_00988 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.55 MIT1002_01936 Molybdopterin-synthase adenylyltransferase low > 70
Variovorax sp. OAS795 0.43 ABID97_RS07920 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.35 ABID97_RS16680 tRNA threonylcarbamoyladenosine dehydratase low > 91
Marinobacter adhaerens HP15 0.42 HP15_1463 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.56 HP15_266 UBA/THIF-type NAD/FAD binding protein low > 73
Castellaniella sp019104865 MT123 0.42 ABCV34_RS06920 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.28 ABCV34_RS00665 tRNA threonylcarbamoyladenosine dehydratase — —
Acinetobacter radioresistens SK82 0.38 MPMX26_02105 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.38 MPMX26_00481 tRNA threonylcarbamoyladenosine dehydratase low > 36

Not shown: 0 genomes with orthologs for PP_2160 only; 5 genomes with orthologs for PP_1527 only