Conservation of cofitness between PP_2327 and PP_1025 in Pseudomonas putida KT2440

68 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_2327 transcriptional dual regulator / CysB-O-acetyl-L-serine 1.0 PP_1025 2-isopropylmalate synthase 0.81 14
Pseudomonas fluorescens FW300-N2E3 0.97 AO353_19060 CysB family transcriptional regulator 0.91 AO353_15925 2-isopropylmalate synthase 0.68 7
Pseudomonas fluorescens FW300-N2C3 0.97 AO356_03180 CysB family transcriptional regulator 0.91 AO356_06550 2-isopropylmalate synthase 0.50 24
Pseudomonas fluorescens FW300-N2E2 0.97 Pf6N2E2_2465 Cys regulon transcriptional activator CysB 0.91 Pf6N2E2_3170 2-isopropylmalate synthase (EC 2.3.3.13) 0.75 11
Pseudomonas fluorescens GW456-L13 0.97 PfGW456L13_2230 Cys regulon transcriptional activator CysB 0.91 PfGW456L13_4854 2-isopropylmalate synthase (EC 2.3.3.13) 0.90 9
Pseudomonas fluorescens FW300-N1B4 0.96 Pf1N1B4_283 Cys regulon transcriptional activator CysB 0.91 Pf1N1B4_847 2-isopropylmalate synthase (EC 2.3.3.13) — —
Pseudomonas sp. RS175 0.96 PFR28_00966 HTH-type transcriptional regulator CysB 0.91 PFR28_00305 2-isopropylmalate synthase 0.35 58
Pseudomonas fluorescens SBW25 0.96 PFLU_RS08410 HTH-type transcriptional regulator CysB 0.91 PFLU_RS24765 2-isopropylmalate synthase low > 109
Pseudomonas fluorescens SBW25-INTG 0.96 PFLU_RS08410 HTH-type transcriptional regulator CysB 0.91 PFLU_RS24765 2-isopropylmalate synthase 0.41 21
Pseudomonas simiae WCS417 0.96 PS417_08460 CysB family transcriptional regulator 0.91 PS417_23110 2-isopropylmalate synthase — —
Pseudomonas sp. S08-1 0.93 OH686_01730 Cys regulon transcriptional activator CysB 0.78 OH686_17570 2-isopropylmalate synthase low > 80
Pseudomonas syringae pv. syringae B728a ΔmexB 0.93 Psyr_2077 regulatory protein, LysR:LysR, substrate-binding protein 0.91 Psyr_1257 2-isopropylmalate synthase 0.64 44
Pseudomonas syringae pv. syringae B728a 0.93 Psyr_2077 regulatory protein, LysR:LysR, substrate-binding protein 0.91 Psyr_1257 2-isopropylmalate synthase 0.83 6
Pseudomonas stutzeri RCH2 0.91 Psest_2329 Transcriptional regulator 0.83 Psest_1277 2-isopropylmalate synthase, yeast type 0.68 26
Marinobacter adhaerens HP15 0.80 HP15_1854 transcriptional regulator, LysR family 0.53 HP15_2055 2-isopropylmalate synthase — —
Vibrio cholerae E7946 ATCC 55056 0.70 CSW01_09545 HTH-type transcriptional regulator CysB 0.11 CSW01_12595 2-isopropylmalate synthase — —
Dickeya dianthicola 67-19 0.69 HGI48_RS10540 HTH-type transcriptional regulator CysB 0.11 HGI48_RS18055 2-isopropylmalate synthase low > 71
Dickeya dadantii 3937 0.68 DDA3937_RS10540 HTH-type transcriptional regulator CysB 0.52 DDA3937_RS02895 2-isopropylmalate synthase low > 74
Alteromonas macleodii MIT1002 0.68 MIT1002_02005 Cys regulon transcriptional activator 0.11 MIT1002_00949 2-isopropylmalate synthase — —
Rahnella sp. WP5 0.68 EX31_RS09890 HTH-type transcriptional regulator CysB 0.57 EX31_RS24130 2-isopropylmalate synthase low > 89
Dickeya dianthicola ME23 0.68 DZA65_RS11020 HTH-type transcriptional regulator CysB 0.11 DZA65_RS19200 2-isopropylmalate synthase 0.66 20
Pectobacterium carotovorum WPP14 0.68 HER17_RS10870 HTH-type transcriptional regulator CysB 0.09 HER17_RS03085 2-isopropylmalate synthase 0.96 2
Serratia liquefaciens MT49 0.68 IAI46_13965 HTH-type transcriptional regulator CysB 0.58 IAI46_09630 2-isopropylmalate synthase — —
Pantoea sp. MT58 0.67 IAI47_09240 HTH-type transcriptional regulator CysB 0.53 IAI47_10235 2-isopropylmalate synthase low > 76
Enterobacter sp. TBS_079 0.67 MPMX20_02501 HTH-type transcriptional regulator CysB 0.56 MPMX20_03565 2-isopropylmalate synthase — —
Enterobacter asburiae PDN3 0.67 EX28DRAFT_0946 Transcriptional regulator 0.57 EX28DRAFT_2770 2-isopropylmalate synthase, yeast type — —
Klebsiella michiganensis M5al 0.67 BWI76_RS11930 LysR family transcriptional regulator CysB 0.55 BWI76_RS22105 2-isopropylmalate synthase — —
Escherichia coli ECOR38 0.67 HEPCGN_25600 cysB HTH-type transcriptional regulator CysB 0.09 HEPCGN_08695 2-isopropylmalate synthase — —
Erwinia tracheiphila SCR3 0.67 LU632_RS12550 cysB HTH-type transcriptional regulator CysB 0.10 LU632_RS02880 leuA 2-isopropylmalate synthase — —
Escherichia coli ECRC101 0.67 OKFHMN_02600 cysB HTH-type transcriptional regulator CysB 0.09 OKFHMN_10715 2-isopropylmalate synthase — —
Escherichia coli ECRC62 0.67 BNILDI_18415 cysB HTH-type transcriptional regulator CysB 0.09 BNILDI_08550 2-isopropylmalate synthase — —
Escherichia coli ECRC101 0.67 MCAODC_15665 cysB HTH-type transcriptional regulator CysB 0.09 MCAODC_01230 2-isopropylmalate synthase — —
Escherichia coli ECRC102 0.67 NIAGMN_26770 cysB HTH-type transcriptional regulator CysB 0.09 NIAGMN_08565 2-isopropylmalate synthase — —
Escherichia coli ECRC99 0.67 KEDOAH_26165 cysB HTH-type transcriptional regulator CysB 0.09 KEDOAH_17440 2-isopropylmalate synthase — —
Escherichia coli ECOR27 0.67 NOLOHH_20265 cysB HTH-type transcriptional regulator CysB 0.09 NOLOHH_03060 2-isopropylmalate synthase — —
Escherichia coli BW25113 0.67 b1275 cysB DNA-binding transcriptional dual regulator, O-acetyl-L-serine-binding (NCBI) 0.09 b0074 leuA 2-isopropylmalate synthase (NCBI) — —
Escherichia fergusonii Becca 0.67 EFB2_02652 HTH-type transcriptional regulator CysB 0.09 EFB2_03971 2-isopropylmalate synthase — —
Escherichia coli BL21 0.67 ECD_01251 N-acetylserine-responsive cysteine regulon transcriptional activator; autorepressor 0.09 ECD_00076 2-isopropylmalate synthase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.67 OHPLBJKB_02409 HTH-type transcriptional regulator CysB 0.09 OHPLBJKB_03583 2-isopropylmalate synthase low > 73
Escherichia coli ECRC98 0.67 JDDGAC_05145 cysB HTH-type transcriptional regulator CysB 0.09 JDDGAC_14310 2-isopropylmalate synthase — —
Escherichia coli Nissle 1917 0.67 ECOLIN_RS07680 HTH-type transcriptional regulator CysB 0.09 ECOLIN_RS00400 2-isopropylmalate synthase low > 52
Shewanella amazonensis SB2B 0.66 Sama_1324 cysB transcriptional regulator CysB (RefSeq) 0.10 Sama_0335 2-isopropylmalate synthase (RefSeq) — —
Shewanella oneidensis MR-1 0.66 SO2649 cysB cys regulon transcriptional activator (NCBI ptt file) 0.10 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.84 18
Shewanella loihica PV-4 0.66 Shew_1624 cysB transcriptional regulator CysB (RefSeq) 0.10 Shew_3472 2-isopropylmalate synthase (RefSeq) — —
Shewanella sp. ANA-3 0.65 Shewana3_1731 cysB transcriptional regulator CysB (RefSeq) 0.10 Shewana3_3761 2-isopropylmalate synthase (RefSeq) — —
Dechlorosoma suillum PS 0.52 Dsui_1988 transcriptional regulator 0.59 Dsui_3227 2-isopropylmalate synthase — —
Burkholderia phytofirmans PsJN 0.49 BPHYT_RS08810 CysB family transcriptional regulator 0.64 BPHYT_RS13280 2-isopropylmalate synthase low > 109
Paraburkholderia graminis OAS925 0.49 ABIE53_001994 LysR family cys regulon transcriptional activator 0.63 ABIE53_002867 2-isopropylmalate synthase low > 113
Paraburkholderia bryophila 376MFSha3.1 0.49 H281DRAFT_00782 transcriptional regulator, LysR family 0.63 H281DRAFT_00385 2-isopropylmalate synthase low > 103
Paraburkholderia sabiae LMG 24235 0.48 QEN71_RS22570 CysB family HTH-type transcriptional regulator 0.57 QEN71_RS01640 2-isopropylmalate synthase low > 153
Hydrogenophaga sp. GW460-11-11-14-LB1 0.48 GFF5044 Alkanesulfonate utilization operon LysR-family regulator CbI 0.62 GFF4280 2-isopropylmalate synthase (EC 2.3.3.13) low > 90
Variovorax sp. SCN45 0.47 GFF3358 Alkanesulfonate utilization operon LysR-family regulator Cbl 0.60 GFF1164 2-isopropylmalate synthase (EC 2.3.3.13) low > 127
Ralstonia sp. UNC404CL21Col 0.47 ABZR87_RS11555 CysB family HTH-type transcriptional regulator 0.63 ABZR87_RS22365 2-isopropylmalate synthase low > 80
Herbaspirillum seropedicae SmR1 0.47 HSERO_RS08245 CysB family transcriptional regulator 0.66 HSERO_RS17185 2-isopropylmalate synthase low > 78
Ralstonia solanacearum UW163 0.46 UW163_RS13430 CysB family HTH-type transcriptional regulator 0.65 UW163_RS17345 2-isopropylmalate synthase — —
Ralstonia solanacearum PSI07 0.46 RPSI07_RS17385 CysB family HTH-type transcriptional regulator 0.64 RPSI07_RS01320 2-isopropylmalate synthase 0.50 65
Ralstonia solanacearum IBSBF1503 0.46 RALBFv3_RS00100 CysB family HTH-type transcriptional regulator 0.65 RALBFv3_RS21840 2-isopropylmalate synthase low > 76
Ralstonia solanacearum GMI1000 0.46 RS_RS06760 CysB family HTH-type transcriptional regulator 0.63 RS_RS18695 2-isopropylmalate synthase 2 low > 80
Variovorax sp. OAS795 0.46 ABID97_RS02980 CysB family HTH-type transcriptional regulator 0.60 ABID97_RS14905 2-isopropylmalate synthase low > 91
Cupriavidus basilensis FW507-4G11 0.45 RR42_RS12245 transcriptional regulator 0.62 RR42_RS21205 2-isopropylmalate synthase low > 128
Acidovorax sp. GW101-3H11 0.44 Ac3H11_2403 Alkanesulfonate utilization operon LysR-family regulator CbI 0.55 Ac3H11_5000 2-isopropylmalate synthase (EC 2.3.3.13) low > 79
Acinetobacter radioresistens SK82 0.40 MPMX26_02171 HTH-type transcriptional regulator SsuR 0.62 MPMX26_00404 2-isopropylmalate synthase low > 36
Castellaniella sp019104865 MT123 0.37 ABCV34_RS08230 CysB family HTH-type transcriptional regulator 0.61 ABCV34_RS12420 2-isopropylmalate synthase 0.61 4
Dyella japonica UNC79MFTsu3.2 0.37 ABZR86_RS05885 LysR substrate-binding domain-containing protein 0.09 ABZR86_RS15970 2-isopropylmalate synthase 0.97 10
Rhodanobacter sp. FW510-T8 0.37 OKGIIK_05975 lysR CysB family transcriptional regulator 0.09 OKGIIK_13575 leuA 2-isopropylmalate synthase low > 52
Rhodanobacter denitrificans FW104-10B01 0.35 LRK54_RS00915 LysR substrate-binding domain-containing protein 0.10 LRK54_RS10345 2-isopropylmalate synthase 0.69 19
Rhodanobacter denitrificans MT42 0.35 LRK55_RS00690 LysR substrate-binding domain-containing protein 0.10 LRK55_RS09985 2-isopropylmalate synthase low > 63
Lysobacter sp. OAE881 0.34 ABIE51_RS15850 LysR family transcriptional regulator 0.10 ABIE51_RS17570 2-isopropylmalate synthase 0.88 57
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.1249.1 Transcriptional regulator 0.10 Xcc-8004.1056.1 2-isopropylmalate synthase (EC 2.3.3.13) low > 74

Not shown: 2 genomes with orthologs for PP_2327 only; 27 genomes with orthologs for PP_1025 only