| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli ECRC100 | 1.0 | OKFHMN_20250 | relA | GTP diphosphokinase | 1.0 | OKFHMN_05575 | lrp | leucine-responsive transcriptional regulator Lrp | 0.80 | 5 |
| Escherichia coli ECRC101 | 1.00 | MCAODC_10775 | relA | GTP diphosphokinase | 1.00 | MCAODC_24965 | lrp | leucine-responsive transcriptional regulator Lrp | low | > 87 |
| Escherichia coli Nissle 1917 | 1.00 | ECOLIN_RS15515 | | GTP diphosphokinase | 1.00 | ECOLIN_RS04730 | | leucine-responsive transcriptional regulator Lrp | low | > 55 |
| Escherichia coli BL21 | 1.00 | ECD_02629 | | (p)ppGpp synthetase I/GTP pyrophosphokinase | 1.00 | ECD_00893 | | leucine-responsive global transcriptional regulator | low | > 61 |
| Escherichia coli ECRC102 | 1.00 | NIAGMN_18020 | relA | GTP diphosphokinase | 1.00 | NIAGMN_03295 | lrp | leucine-responsive transcriptional regulator Lrp | — | — |
| Escherichia coli ECOR38 | 1.00 | HEPCGN_19500 | relA | GTP diphosphokinase | 1.00 | HEPCGN_22935 | lrp | leucine-responsive transcriptional regulator Lrp | low | > 87 |
| Escherichia coli ECRC99 | 1.00 | KEDOAH_07880 | relA | GTP diphosphokinase | 1.00 | KEDOAH_22160 | lrp | leucine-responsive transcriptional regulator Lrp | — | — |
| Escherichia coli ECRC98 | 1.00 | JDDGAC_23915 | relA | GTP diphosphokinase | 1.00 | JDDGAC_09385 | lrp | leucine-responsive transcriptional regulator Lrp | low | > 86 |
| Escherichia coli ECRC62 | 1.00 | BNILDI_10630 | relA | GTP diphosphokinase | 1.00 | BNILDI_20400 | lrp | leucine-responsive transcriptional regulator Lrp | low | > 75 |
| Escherichia coli ECOR27 | 1.00 | NOLOHH_12125 | relA | GTP diphosphokinase | 1.00 | NOLOHH_22145 | lrp | leucine-responsive transcriptional regulator Lrp | low | > 75 |
| Escherichia coli BW25113 | 1.00 | b2784 | relA | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | 1.00 | b0889 | lrp | DNA-binding transcriptional dual regulator, leucine-binding (NCBI) | low | > 76 |
| Escherichia fergusonii Becca | 1.00 | EFB2_01133 | | GTP pyrophosphokinase | 1.00 | EFB2_03172 | | Leucine-responsive regulatory protein | low | > 86 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 1.00 | OHPLBJKB_00947 | | GTP pyrophosphokinase | 1.00 | OHPLBJKB_02779 | | Leucine-responsive regulatory protein | low | > 73 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.96 | GFF4837 | | 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 | 1.00 | GFF4893 | | Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system | low | > 78 |
| Klebsiella michiganensis M5al | 0.94 | BWI76_RS22805 | | GTP diphosphokinase | 1.00 | BWI76_RS09655 | | leucine-responsive regulatory protein | low | > 92 |
| Enterobacter asburiae PDN3 | 0.94 | EX28DRAFT_2864 | | (p)ppGpp synthetase, RelA/SpoT family | 1.00 | EX28DRAFT_2043 | | transcriptional regulator, AsnC family | low | > 76 |
| Enterobacter sp. TBS_079 | 0.93 | MPMX20_03653 | | GTP pyrophosphokinase | 1.00 | MPMX20_01551 | | Leucine-responsive regulatory protein | low | > 85 |
| Dickeya dadantii 3937 | 0.87 | DDA3937_RS17015 | | GTP diphosphokinase | 0.98 | DDA3937_RS09590 | | leucine-responsive transcriptional regulator Lrp | low | > 74 |
| Dickeya dianthicola 67-19 | 0.87 | HGI48_RS17070 | | GTP diphosphokinase | 0.98 | HGI48_RS09605 | | leucine-responsive transcriptional regulator Lrp | low | > 71 |
| Dickeya dianthicola ME23 | 0.87 | DZA65_RS18145 | | GTP diphosphokinase | 0.98 | DZA65_RS09915 | | leucine-responsive transcriptional regulator Lrp | low | > 75 |
| Pectobacterium carotovorum WPP14 | 0.86 | HER17_RS04115 | | GTP diphosphokinase | 0.98 | HER17_RS12360 | | leucine-responsive transcriptional regulator Lrp | low | > 75 |
| Erwinia tracheiphila SCR3 | 0.86 | LU632_RS06350 | relA | GTP diphosphokinase | 0.97 | LU632_RS09740 | lrp | leucine-responsive transcriptional regulator Lrp | 0.73 | 22 |
| Serratia liquefaciens MT49 | 0.85 | IAI46_03600 | | GTP diphosphokinase | 0.98 | IAI46_08555 | | leucine-responsive transcriptional regulator Lrp | low | > 86 |
| Rahnella sp. WP5 | 0.85 | EX31_RS07955 | | GTP diphosphokinase | 0.98 | EX31_RS18530 | | leucine-responsive transcriptional regulator Lrp | 0.81 | 65 |
| Pantoea sp. MT58 | 0.84 | IAI47_04120 | | GTP diphosphokinase | 0.97 | IAI47_12915 | | leucine-responsive transcriptional regulator Lrp | low | > 76 |
| Vibrio cholerae E7946 ATCC 55056 | 0.67 | CSW01_12405 | | GTP diphosphokinase | 0.92 | CSW01_09530 | | leucine-responsive transcriptional regulator Lrp | — | — |
| Shewanella sp. ANA-3 | 0.59 | Shewana3_1111 | | (p)ppGpp synthetase I, SpoT/RelA (RefSeq) | 0.80 | Shewana3_2049 | | leucine-responsive transcriptional regulator (RefSeq) | low | > 73 |
| Shewanella amazonensis SB2B | 0.58 | Sama_1033 | | GTP diphosphokinase (RefSeq) | 0.82 | Sama_1771 | | leucine-responsive transcriptional regulator (RefSeq) | low | > 62 |
| Shewanella oneidensis MR-1 | 0.58 | SO3455 | relA | GTP pyrophosphokinase (NCBI ptt file) | 0.80 | SO2305 | lrp | leucine-responsive regulatory protein (NCBI ptt file) | low | > 76 |
| Shewanella loihica PV-4 | 0.58 | Shew_1202 | | (p)ppGpp synthetase I, SpoT/RelA (RefSeq) | 0.83 | Shew_2025 | | leucine-responsive transcriptional regulator (RefSeq) | low | > 60 |
| Alteromonas macleodii MIT1002 | 0.53 | MIT1002_00794 | | GTP pyrophosphokinase | 0.66 | MIT1002_02181 | | Leucine-responsive regulatory protein | low | > 70 |
| Pseudomonas sp. RS175 | 0.47 | PFR28_03223 | | GTP pyrophosphokinase | 0.58 | PFR28_04400 | | Leucine-responsive regulatory protein | low | > 88 |
| Pseudomonas fluorescens GW456-L13 | 0.47 | PfGW456L13_2035 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.58 | PfGW456L13_811 | | Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system | low | > 87 |
| Pseudomonas fluorescens FW300-N2C3 | 0.47 | AO356_19060 | | (p)ppGpp synthetase | 0.58 | AO356_12615 | | AsnC family transcriptional regulator | low | > 104 |
| Pseudomonas sp. S08-1 | 0.47 | OH686_18960 | | Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase , (p)ppGpp synthetase I | 0.58 | OH686_13680 | | Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system | low | > 80 |
| Pseudomonas fluorescens FW300-N2E2 | 0.47 | Pf6N2E2_5723 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.58 | Pf6N2E2_4390 | | Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system | low | > 103 |
| Pseudomonas fluorescens FW300-N2E3 | 0.47 | AO353_02710 | | (p)ppGpp synthetase | 0.58 | AO353_09160 | | AsnC family transcriptional regulator | low | > 101 |
| Pseudomonas fluorescens SBW25-INTG | 0.47 | PFLU_RS22095 | | GTP diphosphokinase | 0.58 | PFLU_RS29385 | | AsnC family transcriptional regulator | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.47 | PFLU_RS22095 | | GTP diphosphokinase | 0.58 | PFLU_RS29385 | | AsnC family transcriptional regulator | low | > 109 |
| Pseudomonas simiae WCS417 | 0.47 | PS417_20150 | | (p)ppGpp synthetase | 0.58 | PS417_27710 | | AsnC family transcriptional regulator | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.47 | Pf1N1B4_3508 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.58 | Pf1N1B4_2143 | | Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system | low | > 87 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.47 | Psyr_3695 | | RelA/SpoT protein | 0.59 | Psyr_0234 | | transcriptional regulator, AsnC family | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.47 | Psyr_3695 | | RelA/SpoT protein | 0.59 | Psyr_0234 | | transcriptional regulator, AsnC family | low | > 86 |
| Pseudomonas putida KT2440 | 0.46 | PP_1656 | | ATP:GTP 3'-pyrophosphotransferase | 0.58 | PP_5271 | | DNA-binding transcriptional dual regulator, leucine-binding | low | > 96 |
| Pseudomonas stutzeri RCH2 | 0.46 | Psest_1640 | | (p)ppGpp synthetase, RelA/SpoT family | 0.57 | Psest_3794 | | Transcriptional regulators | low | > 67 |
| Marinobacter adhaerens HP15 | 0.45 | HP15_791 | | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA | 0.47 | HP15_2690 | | transcriptional regulator, AsnC family | low | > 73 |
| Kangiella aquimarina DSM 16071 | 0.43 | B158DRAFT_2277 | | (p)ppGpp synthetase, RelA/SpoT family | 0.67 | B158DRAFT_1822 | | Transcriptional regulators | low | > 40 |
| Rhodanobacter sp. FW510-T8 | 0.39 | OKGIIK_02170 | relA | GTP diphosphokinase | 0.55 | OKGIIK_06660 | lrp | AsnC family transcriptional regulator | low | > 52 |
| Rhodanobacter denitrificans FW104-10B01 | 0.39 | LRK54_RS12725 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.54 | LRK54_RS00595 | | winged helix-turn-helix transcriptional regulator | low | > 59 |
| Rhodanobacter denitrificans MT42 | 0.39 | LRK55_RS12430 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.54 | LRK55_RS00365 | | winged helix-turn-helix transcriptional regulator | low | > 63 |
| Dechlorosoma suillum PS | 0.37 | Dsui_2816 | | (p)ppGpp synthetase, RelA/SpoT family | 0.38 | Dsui_3228 | | transcriptional regulator | low | > 51 |
| Herbaspirillum seropedicae SmR1 | 0.36 | HSERO_RS09855 | | GTP pyrophosphokinase | 0.59 | HSERO_RS00865 | | AsnC family transcriptional regulator | low | > 78 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.36 | Xcc-8004.1489.1 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I | 0.58 | Xcc-8004.4622.1 | | Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system | low | > 74 |
| Ralstonia sp. UNC404CL21Col | 0.36 | ABZR87_RS13745 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.57 | ABZR87_RS09565 | | Lrp/AsnC ligand binding domain-containing protein | low | > 80 |
| Acinetobacter radioresistens SK82 | 0.36 | MPMX26_00539 | | GTP pyrophosphokinase | 0.49 | MPMX26_01467 | | Leucine-responsive regulatory protein | low | > 36 |
| Ralstonia solanacearum PSI07 | 0.36 | RPSI07_RS15685 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.57 | RPSI07_RS19595 | | AsnC family transcriptional regulator | low | > 81 |
| Ralstonia solanacearum GMI1000 | 0.36 | RS_RS07930 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.56 | RS_RS04610 | | AsnC family transcriptional regulator | low | > 80 |
| Paraburkholderia sabiae LMG 24235 | 0.36 | QEN71_RS05265 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.55 | QEN71_RS04195 | | Lrp/AsnC ligand binding domain-containing protein | low | > 153 |
| Ralstonia solanacearum UW163 | 0.35 | UW163_RS15115 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.56 | UW163_RS15935 | | AsnC family transcriptional regulator | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.35 | RALBFv3_RS01805 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.56 | RALBFv3_RS13875 | | AsnC family transcriptional regulator | low | > 76 |
| Cupriavidus basilensis FW507-4G11 | 0.35 | RR42_RS06585 | | GTP pyrophosphokinase | 0.53 | RR42_RS04590 | | AsnC family transcriptional regulator | low | > 128 |
| Burkholderia phytofirmans PsJN | 0.35 | BPHYT_RS13655 | | GTP pyrophosphokinase | 0.55 | BPHYT_RS14785 | | AsnC family transcriptional regulator | 0.31 | 7 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.34 | H281DRAFT_04499 | | GTP pyrophosphokinase | 0.54 | H281DRAFT_04288 | | transcriptional regulator, AsnC family | low | > 103 |
| Paraburkholderia graminis OAS925 | 0.34 | ABIE53_002905 | | GTP pyrophosphokinase | 0.54 | ABIE53_003132 | | Lrp/AsnC family leucine-responsive transcriptional regulator | low | > 113 |
| Lysobacter sp. OAE881 | 0.34 | ABIE51_RS05170 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.38 | ABIE51_RS00930 | | Lrp/AsnC family transcriptional regulator | low | > 62 |
| Acidovorax sp. GW101-3H11 | 0.33 | Ac3H11_362 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I | 0.56 | Ac3H11_2849 | | PutR, transcriptional activator of PutA and PutP | low | > 79 |
| Castellaniella sp019104865 MT123 | 0.33 | ABCV34_RS08440 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.51 | ABCV34_RS10805 | | winged helix-turn-helix transcriptional regulator | 0.82 | 33 |
| Variovorax sp. SCN45 | 0.32 | GFF403 | | Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I | 0.55 | GFF3756 | | Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system | low | > 127 |
| Bacteroides ovatus ATCC 8483 | 0.24 | BACOVA_02404 | | RelA/SpoT family protein | 0.33 | BACOVA_03031 | | transcriptional regulator, AsnC family | low | > 94 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.24 | BT0700 | | GTP pyrophosphokinase (NCBI ptt file) | 0.33 | BT2386 | | AsnC family transcriptional regulator (NCBI ptt file) | 0.48 | 43 |
Not shown: 2 genomes with orthologs for OKFHMN_20250 only; 21 genomes with orthologs for OKFHMN_05575 only