Conservation of cofitness between NOLOHH_13075 and NOLOHH_12070 in Escherichia coli ECOR27

70 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR27 1.0 NOLOHH_13075 lepA translation elongation factor 4 1.0 NOLOHH_12070 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.66 19
Escherichia coli ECRC98 1.00 JDDGAC_25065 lepA translation elongation factor 4 0.99 JDDGAC_23855 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 86
Escherichia coli ECRC102 1.00 NIAGMN_19170 lepA translation elongation factor 4 0.99 NIAGMN_17960 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF — —
Escherichia coli ECRC99 1.00 KEDOAH_06820 lepA translation elongation factor 4 0.99 KEDOAH_07940 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF — —
Escherichia coli ECRC100 1.00 OKFHMN_21400 lepA translation elongation factor 4 0.99 OKFHMN_20190 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 80
Escherichia coli Nissle 1917 1.00 ECOLIN_RS14540 translation elongation factor 4 1.00 ECOLIN_RS15580 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 55
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01138 Elongation factor 4 0.99 OHPLBJKB_00937 NADPH-dependent 7-cyano-7-deazaguanine reductase low > 73
Escherichia coli ECOR38 1.00 HEPCGN_20545 lepA translation elongation factor 4 1.00 HEPCGN_19445 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 87
Escherichia coli ECRC62 1.00 BNILDI_11875 lepA translation elongation factor 4 1.00 BNILDI_10575 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.57 13
Escherichia coli BL21 1.00 ECD_02463 back-translocating elongation factor EF4, GTPase 0.99 ECD_02639 7-cyano-7-deazaguanine reductase (NADPH-dependent) low > 61
Escherichia coli BW25113 1.00 b2569 lepA GTP-binding protein LepA (NCBI) 0.99 b2794 yqcD hypothetical protein (NCBI) low > 76
Escherichia coli ECRC101 1.00 MCAODC_11930 lepA translation elongation factor 4 0.99 MCAODC_10715 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.59 2
Escherichia fergusonii Becca 1.00 EFB2_01327 Elongation factor 4 1.00 EFB2_01123 NADPH-dependent 7-cyano-7-deazaguanine reductase low > 86
Klebsiella michiganensis M5al 0.94 BWI76_RS21335 elongation factor 4 0.87 BWI76_RS22865 NADPH-dependent 7-cyano-7-deazaguanine reductase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF2477 Translation elongation factor LepA 0.90 GFF4849 NADPH dependent preQ0 reductase (EC 1.7.1.13) low > 78
Enterobacter asburiae PDN3 0.94 EX28DRAFT_0076 elongation factor 4 0.88 EX28DRAFT_2876 7-cyano-7-deazaguanine reductase low > 76
Enterobacter sp. TBS_079 0.93 MPMX20_03440 Elongation factor 4 0.87 MPMX20_03664 NADPH-dependent 7-cyano-7-deazaguanine reductase low > 85
Dickeya dadantii 3937 0.92 DDA3937_RS15745 elongation factor 4 0.55 DDA3937_RS04655 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 74
Dickeya dianthicola 67-19 0.92 HGI48_RS15830 elongation factor 4 0.54 HGI48_RS04615 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.68 36
Dickeya dianthicola ME23 0.92 DZA65_RS16910 elongation factor 4 0.54 DZA65_RS04535 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 75
Erwinia tracheiphila SCR3 0.92 LU632_RS15395 lepA translation elongation factor 4 0.77 LU632_RS06280 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 74
Pectobacterium carotovorum WPP14 0.92 HER17_RS05805 translation elongation factor 4 0.75 HER17_RS16390 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 75
Serratia liquefaciens MT49 0.91 IAI46_19560 elongation factor 4 0.56 IAI46_21580 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 86
Rahnella sp. WP5 0.91 EX31_RS21825 elongation factor 4 0.80 EX31_RS13085 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 89
Pantoea sp. MT58 0.89 IAI47_04870 elongation factor 4 0.75 IAI47_04050 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 76
Vibrio cholerae E7946 ATCC 55056 0.85 CSW01_12465 elongation factor 4 0.63 CSW01_04620 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 62
Shewanella sp. ANA-3 0.83 Shewana3_3028 GTP-binding protein LepA (RefSeq) 0.64 Shewana3_2835 queF 7-cyano-7-deazaguanine reductase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.83 SO1346 lepA GTP-binding protein LepA (NCBI ptt file) 0.64 SO1608 conserved hypothetical protein (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.82 Shew_1052 GTP-binding protein LepA (RefSeq) 0.63 Shew_2654 queF 7-cyano-7-deazaguanine reductase (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.81 MIT1002_02715 Elongation factor 4 0.54 MIT1002_00988 NADPH-dependent 7-cyano-7-deazaguanine reductase low > 70
Kangiella aquimarina DSM 16071 0.81 B158DRAFT_2184 GTP-binding protein LepA 0.51 B158DRAFT_2159 7-cyano-7-deazaguanine reductase low > 40
Shewanella amazonensis SB2B 0.80 Sama_0878 GTP-binding protein LepA (RefSeq) 0.60 Sama_1120 queF 7-cyano-7-deazaguanine reductase (RefSeq) low > 62
Pseudomonas sp. S08-1 0.76 OH686_20065 elongation factor 4 0.47 OH686_22700 queuine synthase low > 80
Pseudomonas sp. RS175 0.76 PFR28_03525 Elongation factor 4 0.48 PFR28_01136 NADPH-dependent 7-cyano-7-deazaguanine reductase — —
Pseudomonas putida KT2440 0.76 PP_1431 Elongation factor 4 0.47 PP_2160 NADPH-dependent 7-cyano-7-deazaguanine reductase — —
Pseudomonas fluorescens SBW25 0.75 PFLU_RS05250 elongation factor 4 0.48 PFLU_RS07770 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 109
Pseudomonas fluorescens SBW25-INTG 0.75 PFLU_RS05250 elongation factor 4 0.48 PFLU_RS07770 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 109
Pseudomonas fluorescens GW456-L13 0.75 PfGW456L13_4842 Translation elongation factor LepA 0.47 PfGW456L13_4015 NADPH dependent preQ0 reductase (EC 1.7.1.13) 0.53 7
Pseudomonas fluorescens FW300-N2E2 0.75 Pf6N2E2_5423 Translation elongation factor LepA 0.48 Pf6N2E2_2264 NADPH dependent preQ0 reductase (EC 1.7.1.13) — —
Pseudomonas fluorescens FW300-N2C3 0.75 AO356_17485 elongation factor 4 0.48 AO356_02205 NADPH-dependent 7-cyano-7-deazaguanine reductase low > 104
Pseudomonas simiae WCS417 0.75 PS417_05180 elongation factor 4 0.48 PS417_07695 NADPH-dependent 7-cyano-7-deazaguanine reductase — —
Pseudomonas stutzeri RCH2 0.75 Psest_3095 GTP-binding protein LepA 0.49 Psest_2714 7-cyano-7-deazaguanine reductase — —
Pseudomonas fluorescens FW300-N2E3 0.75 AO353_04520 elongation factor 4 0.48 AO353_00345 NADPH-dependent 7-cyano-7-deazaguanine reductase low > 101
Pseudomonas fluorescens FW300-N1B4 0.75 Pf1N1B4_895 Translation elongation factor LepA 0.48 Pf1N1B4_65 NADPH dependent preQ0 reductase (EC 1.7.1.13) — —
Pseudomonas syringae pv. syringae B728a 0.74 Psyr_3954 GTP-binding protein LepA 0.48 Psyr_1907 GTP cyclohydrolase I 0.59 2
Pseudomonas syringae pv. syringae B728a ΔmexB 0.74 Psyr_3954 GTP-binding protein LepA 0.48 Psyr_1907 GTP cyclohydrolase I — —
Marinobacter adhaerens HP15 0.74 HP15_781 GTP-binding protein LepA 0.43 HP15_1463 NADPH-dependent 7-cyano-7-deazaguanine reductase low > 73
Acinetobacter radioresistens SK82 0.73 MPMX26_02159 Elongation factor 4 0.36 MPMX26_02105 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.62 31
Herbaspirillum seropedicae SmR1 0.73 HSERO_RS09650 elongation factor 4 0.47 HSERO_RS19515 7-cyano-7-deazaguanine reductase low > 78
Burkholderia phytofirmans PsJN 0.73 BPHYT_RS14380 elongation factor 4 0.47 BPHYT_RS03135 NADPH-dependent 7-cyano-7-deazaguanine reductase low > 109
Paraburkholderia bryophila 376MFSha3.1 0.72 H281DRAFT_04360 GTP-binding protein LepA 0.47 H281DRAFT_01889 7-cyano-7-deazaguanine reductase 0.65 3
Paraburkholderia graminis OAS925 0.72 ABIE53_003038 GTP-binding protein LepA 0.46 ABIE53_000759 7-cyano-7-deazaguanine reductase 0.56 14
Rhodanobacter sp. FW510-T8 0.71 OKGIIK_07885 Elongation factor 4 0.49 OKGIIK_13395 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 52
Cupriavidus basilensis FW507-4G11 0.71 RR42_RS14055 elongation factor 4 0.48 RR42_RS02310 NADPH-dependent 7-cyano-7-deazaguanine reductase low > 128
Rhodanobacter denitrificans MT42 0.70 LRK55_RS16670 translation elongation factor 4 0.47 LRK55_RS10150 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 63
Rhodanobacter denitrificans FW104-10B01 0.70 LRK54_RS16955 translation elongation factor 4 0.47 LRK54_RS10510 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 59
Paraburkholderia sabiae LMG 24235 0.70 QEN71_RS04600 translation elongation factor 4 0.47 QEN71_RS01975 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 153
Dyella japonica UNC79MFTsu3.2 0.70 ABZR86_RS07165 translation elongation factor 4 0.49 ABZR86_RS16195 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 74
Dechlorosoma suillum PS 0.70 Dsui_2457 GTP-binding protein LepA 0.49 Dsui_0505 7-cyano-7-deazaguanine reductase low > 51
Ralstonia solanacearum PSI07 0.70 RPSI07_RS18990 elongation factor 4 0.49 RPSI07_RS21815 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 81
Lysobacter sp. OAE881 0.70 ABIE51_RS13875 translation elongation factor 4 0.42 ABIE51_RS00515 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 62
Castellaniella sp019104865 MT123 0.70 ABCV34_RS08335 translation elongation factor 4 0.40 ABCV34_RS06920 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF — —
Ralstonia sp. UNC404CL21Col 0.69 ABZR87_RS10190 translation elongation factor 4 0.48 ABZR87_RS07355 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.60 61
Xanthomonas campestris pv. campestris strain 8004 0.69 Xcc-8004.3676.1 Translation elongation factor LepA 0.42 Xcc-8004.4789.1 NADPH dependent preQ0 reductase (EC 1.7.1.13) low > 74
Variovorax sp. SCN45 0.68 GFF3867 Translation elongation factor LepA 0.45 GFF6017 NADPH-dependent 7-cyano-7-deazaguanine reductase (EC 1.7.1.13) low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.68 GFF3343 Translation elongation factor LepA 0.47 GFF722 NADPH dependent preQ0 reductase (EC 1.7.1.13) low > 90
Acidovorax sp. GW101-3H11 0.68 Ac3H11_1569 Translation elongation factor LepA 0.45 Ac3H11_1595 NADPH dependent preQ0 reductase (EC 1.7.1.13) low > 79
Variovorax sp. OAS795 0.68 ABID97_RS08350 translation elongation factor 4 0.44 ABID97_RS07920 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 91
Ralstonia solanacearum IBSBF1503 0.68 RALBFv3_RS14470 elongation factor 4 0.49 RALBFv3_RS11390 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 76
Ralstonia solanacearum UW163 0.68 UW163_RS11935 elongation factor 4 0.49 UW163_RS02195 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF — —
Ralstonia solanacearum GMI1000 0.68 RS_RS05250 elongation factor 4 0.49 RS_RS02220 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF — —

Not shown: 31 genomes with orthologs for NOLOHH_13075 only; 0 genomes with orthologs for NOLOHH_12070 only