Conservation of cofitness between CSW01_11565 and CSW01_19080 in Vibrio cholerae E7946 ATCC 55056

87 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_11565 transcriptional regulator NrdR 1.0 CSW01_19080 alkene reductase 0.46 13
Pantoea sp. MT58 0.81 IAI47_14775 transcriptional regulator NrdR 0.52 IAI47_20720 alkene reductase low > 76
Pantoea agglomerans CFBP13505 P0401 0.81 PagCFBP13516_RS15025 nrdR transcriptional regulator NrdR 0.52 PagCFBP13516_RS21080 alkene reductase
Escherichia coli ECRC101 0.81 MCAODC_27685 nrdR transcriptional regulator NrdR 0.46 MCAODC_17975 nemA N-ethylmaleimide reductase low > 87
Escherichia coli BL21 0.81 ECD_00361 Nrd regulon repressor 0.46 ECD_01620 chromate reductase, quinone reductase, FMN-linked; N-Ethylmaleimide reductase; old yellow enzyme low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.81 OHPLBJKB_03263 Transcriptional repressor NrdR 0.46 OHPLBJKB_02075 N-ethylmaleimide reductase low > 74
Escherichia coli ECOR38 0.81 HEPCGN_07085 nrdR transcriptional regulator NrdR 0.46 HEPCGN_05820 nemA N-ethylmaleimide reductase low > 88
Escherichia coli ECRC102 0.81 NIAGMN_06515 nrdR transcriptional regulator NrdR 0.46 NIAGMN_00630 nemA N-ethylmaleimide reductase low > 80
Escherichia coli Nissle 1917 0.81 ECOLIN_RS02500 transcriptional regulator NrdR 0.46 ECOLIN_RS09200 N-ethylmaleimide reductase low > 55
Escherichia coli ECRC100 0.81 OKFHMN_08460 nrdR transcriptional regulator NrdR 0.46 OKFHMN_27435 nemA N-ethylmaleimide reductase low > 79
Escherichia coli ECRC62 0.81 BNILDI_22820 nrdR transcriptional regulator NrdR 0.46 BNILDI_16745 nemA N-ethylmaleimide reductase
Escherichia coli ECRC98 0.81 JDDGAC_12115 nrdR transcriptional regulator NrdR 0.46 JDDGAC_02025 nemA N-ethylmaleimide reductase low > 87
Escherichia fergusonii Becca 0.81 EFB2_03644 Transcriptional repressor NrdR 0.46 EFB2_02342 N-ethylmaleimide reductase low > 86
Escherichia coli ECOR27 0.81 NOLOHH_01405 nrdR transcriptional regulator NrdR 0.46 NOLOHH_17955 nemA N-ethylmaleimide reductase low > 75
Escherichia coli ECRC99 0.81 KEDOAH_19505 nrdR transcriptional regulator NrdR 0.46 KEDOAH_00675 nemA N-ethylmaleimide reductase
Escherichia coli BW25113 0.81 b0413 ybaD hypothetical protein (NCBI) 0.46 b1650 nemA N-ethylmaleimide reductase, FMN-linked (NCBI)
Enterobacter asburiae PDN3 0.80 EX28DRAFT_2557 transcriptional regulator NrdR 0.59 EX28DRAFT_1386 NADH:flavin oxidoreductases, Old Yellow Enzyme family
Enterobacter sp. TBS_079 0.80 MPMX20_01005 Transcriptional repressor NrdR 0.59 MPMX20_02166 N-ethylmaleimide reductase low > 85
Rahnella sp. WP5 0.80 EX31_RS22120 transcriptional regulator NrdR 0.47 EX31_RS13805 alkene reductase low > 89
Dickeya dianthicola 67-19 0.79 HGI48_RS05560 transcriptional regulator NrdR 0.45 HGI48_RS12730 alkene reductase low > 71
Dickeya dianthicola ME23 0.79 DZA65_RS05885 transcriptional regulator NrdR 0.45 DZA65_RS04670 alkene reductase low > 75
Dickeya dadantii 3937 0.79 DDA3937_RS05500 transcriptional regulator NrdR 0.37 DDA3937_RS14735 alkene reductase low > 74
Serratia liquefaciens MT49 0.79 IAI46_04890 transcriptional regulator NrdR 0.46 IAI46_11280 alkene reductase low > 87
Shewanella oneidensis MR-1 0.79 SO3470 conserved hypothetical protein TIGR00244 (NCBI ptt file) 0.68 SO4153 N-ethylmaleimide reductase, putative (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.79 Shew_1186 transcriptional regulator NrdR (RefSeq) 0.69 Shew_0507 NADH:flavin oxidoreductase/NADH oxidase (RefSeq) low > 60
Klebsiella michiganensis M5al 0.79 BWI76_RS06345 transcriptional regulator NrdR 0.45 BWI76_RS16475 alkene reductase
Erwinia amylovora T8 0.79 OLJFJH_18095 transcriptional regulator NrdR 0.49 OLJFJH_03220 alkene reductase low > 58
Pectobacterium carotovorum WPP14 0.79 HER17_RS15965 transcriptional regulator NrdR 0.43 HER17_RS14310 alkene reductase low > 75
Klebsiella pneumoniae MKP103 0.78 KDGMDA_14435 transcriptional regulator NrdR 0.46 KDGMDA_23420 alkene reductase low > 94
Klebsiella pneumoniae MRSN742743 0.78 GJGHJB_03905 nrdR transcriptional regulator NrdR 0.46 GJGHJB_02192 fadH Alkene reductase low > 83
Alteromonas macleodii MIT1002 0.76 MIT1002_02701 Transcriptional repressor NrdR 0.52 MIT1002_01213 N-ethylmaleimide reductase low > 70
Pseudomonas sp. S08-1 0.75 OH686_15690 transcriptional regulator NrdR 0.39 OH686_06200 NADH:flavin , Old Yellow Enzyme family low > 80
Pseudomonas stutzeri RCH2 0.74 Psest_3553 transcriptional regulator NrdR 0.52 Psest_0753 NADH:flavin oxidoreductases, Old Yellow Enzyme family
Pseudomonas protegens RBAN4 0.73 FABNJH_27800 nrdR transcriptional regulator NrdR 0.42 FABNJH_14595 N-ethylmaleimide reductase
Pseudomonas fluorescens FW300-N2E3 0.73 AO353_06720 NrdR family transcriptional regulator 0.42 AO353_28430 N-ethylmaleimide reductase low > 101
Pseudomonas syringae pv. syringae B728a ΔmexB 0.72 Psyr_4463 Protein of unknown function DUF193 0.39 Psyr_4053 NADH:flavin oxidoreductase/NADH oxidase low > 86
Pseudomonas simiae WCS417 0.72 PS417_25270 NrdR family transcriptional regulator 0.49 PS417_11190 oxidoreductase low > 88
Pseudomonas syringae pv. syringae B728a 0.72 Psyr_4463 Protein of unknown function DUF193 0.39 Psyr_4053 NADH:flavin oxidoreductase/NADH oxidase low > 86
Pseudomonas orientalis W4I3 0.72 QF045_RS27235 transcriptional regulator NrdR 0.41 QF045_RS09550 alkene reductase low > 93
Pseudomonas fluorescens FW300-N2C3 0.72 AO356_14925 NrdR family transcriptional regulator 0.43 AO356_25340 NADH:flavin oxidoreductase
Pseudomonas fluorescens FW300-N1B4 0.72 Pf1N1B4_2648 Ribonucleotide reductase transcriptional regulator NrdR 0.43 Pf1N1B4_4194 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)
Pseudomonas fluorescens GW456-L13 0.72 PfGW456L13_1312 Ribonucleotide reductase transcriptional regulator NrdR 0.39 PfGW456L13_4578 NADH:flavin oxidoreductases, Old Yellow Enzyme family low > 87
Pseudomonas segetis P6 0.72 ACVTMO_RS04900 nrdR transcriptional regulator NrdR 0.40 ACVTMO_RS18580 alkene reductase low > 75
Pseudomonas sp. SVBP6 0.72 COO64_RS15895 nrdR transcriptional regulator NrdR 0.47 COO64_RS09205 alkene reductase low > 91
Pseudomonas aeruginosa PUPa3 0.72 NPBIFN_00905 nrdR transcriptional regulator NrdR 0.49 NPBIFN_02080 Alkene reductase low > 101
Pseudomonas sp. BP01 0.72 JOY50_RS20130 nrdR transcriptional regulator NrdR 0.45 JOY50_RS12375 alkene reductase
Pseudomonas aeruginosa PA14 0.72 IKLFDK_20915 transcriptional regulator NrdR 0.49 IKLFDK_14895 alkene reductase low > 98
Pseudomonas aeruginosa MRSN321 0.72 PFGADD_00900 nrdR transcriptional regulator NrdR 0.49 PFGADD_02041 Alkene reductase low > 99
Pseudomonas putida KT2440 0.72 PP_0513 DNA-binding transcriptional repressor NrdR-Zn2+-ATP/dATP 0.50 PP_2486 NADH-dependent flavin oxidoreductase, Oye family low > 96
Pseudomonas sp. DMC3 0.72 GFF3826 Transcriptional repressor NrdR 0.49 GFF2798 N-ethylmaleimide reductase low > 89
Pseudomonas fluorescens SBW25 0.71 PFLU_RS26905 transcriptional regulator NrdR 0.49 PFLU_RS11775 alkene reductase low > 109
Pseudomonas fluorescens SBW25-INTG 0.71 PFLU_RS26905 transcriptional regulator NrdR 0.49 PFLU_RS11775 alkene reductase low > 109
Pseudomonas lactucae CFBP13502 0.71 GEMAOFIL_05159 Transcriptional repressor NrdR 0.48 GEMAOFIL_02538 N-ethylmaleimide reductase low > 96
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.69 GFF4317 Ribonucleotide reductase transcriptional regulator NrdR 0.47 GFF3624 N-ethylmaleimide reductase (EC 1.-.-.-) low > 78
Acinetobacter baumannii LAC-4 0.61 RR41_RS17860 transcriptional regulator NrdR 0.46 RR41_RS16240 alkene reductase low > 55
Acinetobacter radioresistens SK82 0.60 MPMX26_00151 Transcriptional repressor NrdR 0.46 MPMX26_00886 N-ethylmaleimide reductase low > 36
Herbaspirillum seropedicae SmR1 0.59 HSERO_RS06145 NrdR family transcriptional regulator 0.43 HSERO_RS15610 NADH:flavin oxidoreductase low > 78
Xanthomonas campestris pv. campestris strain 8004 0.58 Xcc-8004.4397.1 Ribonucleotide reductase transcriptional regulator NrdR 0.40 Xcc-8004.3623.1 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)
Methylophilus sp. DMC18 0.55 GFF73 Transcriptional repressor NrdR 0.43 GFF937 N-ethylmaleimide reductase low > 43
Cupriavidus basilensis FW507-4G11 0.54 RR42_RS15490 NrdR family transcriptional regulator 0.47 RR42_RS06385 N-ethylmaleimide reductase low > 128
Ralstonia solanacearum GMI1000 0.52 RS_RS03665 transcriptional regulator NrdR 0.48 RS_RS06020 alkene reductase low > 80
Ralstonia solanacearum IBSBF1503 0.52 RALBFv3_RS12890 transcriptional regulator NrdR 0.40 RALBFv3_RS20595 alkene reductase low > 76
Ralstonia solanacearum PSI07 0.52 RPSI07_RS20335 transcriptional regulator NrdR 0.48 RPSI07_RS18165 alkene reductase low > 81
Ralstonia solanacearum UW163 0.52 UW163_RS00675 transcriptional regulator NrdR 0.40 UW163_RS18580 alkene reductase
Ralstonia sp. UNC404CL21Col 0.52 ABZR87_RS08950 transcriptional regulator NrdR 0.47 ABZR87_RS10850 alkene reductase low > 80
Paraburkholderia bryophila 376MFSha3.1 0.51 H281DRAFT_04727 transcriptional repressor NrdR 0.45 H281DRAFT_06090 N-ethylmaleimide reductase low > 103
Paraburkholderia graminis OAS925 0.51 ABIE53_000889 transcriptional repressor NrdR 0.48 ABIE53_001750 N-ethylmaleimide reductase low > 113
Paraburkholderia sabiae LMG 24235 0.51 QEN71_RS26230 transcriptional regulator NrdR 0.50 QEN71_RS38950 alkene reductase low > 153
Burkholderia phytofirmans PsJN 0.51 BPHYT_RS03730 transcriptional repressor NrdR 0.45 BPHYT_RS27240 N-ethylmaleimide reductase low > 109
Dechlorosoma suillum PS 0.51 Dsui_1266 transcriptional regulator NrdR 0.40 Dsui_1877 NADH:flavin oxidoreductase low > 51
Magnetospirillum magneticum AMB-1 0.49 AMB_RS10475 transcriptional regulator NrdR 0.37 AMB_RS16690 alkene reductase low > 64
Azospirillum brasilense Sp245 0.49 AZOBR_RS10020 NrdR family transcriptional regulator 0.41 AZOBR_RS04305 1 2-oxophytodienoate reductase
Variovorax sp. SCN45 0.49 GFF561 Ribonucleotide reductase transcriptional regulator NrdR 0.42 GFF3328 NADH:flavin oxidoreductases, Old Yellow Enzyme family low > 127
Variovorax sp. OAS795 0.49 ABID97_RS17895 transcriptional regulator NrdR 0.41 ABID97_RS02870 alkene reductase low > 91
Azospirillum sp. SherDot2 0.49 MPMX19_00728 Transcriptional repressor NrdR 0.44 MPMX19_04479 N-ethylmaleimide reductase low > 112
Castellaniella sp019104865 MT123 0.47 ABCV34_RS10550 transcriptional regulator NrdR 0.42 ABCV34_RS07505 alkene reductase low > 48
Hydrogenophaga sp. GW460-11-11-14-LB1 0.47 GFF5153 Ribonucleotide reductase transcriptional regulator NrdR 0.56 GFF2159 N-ethylmaleimide reductase low > 90
Rhodospirillum rubrum S1H 0.46 Rru_A1826 Protein of unknown function DUF193 (NCBI) 0.38 Rru_A0475 NADH:flavin oxidoreductase/NADH oxidase (NCBI)
Sinorhizobium meliloti 1021 0.45 SMc01771 transcriptional regulator NrdR 0.42 SMc01227 glycerol trinitrate (GTN) reductase
Sphingomonas koreensis DSMZ 15582 0.45 Ga0059261_1985 transcriptional regulator NrdR 0.37 Ga0059261_2330 NADH:flavin oxidoreductases, Old Yellow Enzyme family low > 68
Agrobacterium fabrum C58 0.45 Atu1166 hypothetical protein 0.44 Atu5445 oxidoreductase
Rhodopseudomonas palustris CGA009 0.45 TX73_014120 transcriptional regulator NrdR 0.42 TX73_022825 alkene reductase
Acidovorax sp. GW101-3H11 0.44 Ac3H11_2922 Ribonucleotide reductase transcriptional regulator NrdR 0.40 Ac3H11_4975 Oxidoreductase, FMN-binding
Rhizobium sp. OAE497 0.43 ABIE40_RS06720 transcriptional regulator NrdR 0.41 ABIE40_RS12885 alkene reductase low > 107
Bosea sp. OAE506 0.42 ABIE41_RS19765 transcriptional regulator NrdR 0.39 ABIE41_RS08040 alkene reductase
Xanthobacter sp. DMC5 0.42 GFF576 Transcriptional repressor NrdR 0.43 GFF2396 N-ethylmaleimide reductase
Sphingobium sp. HT1-2 0.42 GFF3899 Ribonucleotide reductase transcriptional regulator NrdR 0.37 GFF3259 NADH:flavin oxidoreductases, Old Yellow Enzyme family
Synechococcus elongatus PCC 7942 0.41 Synpcc7942_0695 hypothetical protein 0.44 Synpcc7942_0473 NADH:flavin oxidoreductase Old Yellow Enzyme family-like low > 38

Not shown: 21 genomes with orthologs for CSW01_11565 only; 4 genomes with orthologs for CSW01_19080 only