| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_11565 | | transcriptional regulator NrdR | 1.0 | CSW01_19080 | | alkene reductase | 0.46 | 13 |
| Pantoea sp. MT58 | 0.81 | IAI47_14775 | | transcriptional regulator NrdR | 0.52 | IAI47_20720 | | alkene reductase | low | > 76 |
| Pantoea agglomerans CFBP13505 P0401 | 0.81 | PagCFBP13516_RS15025 | nrdR | transcriptional regulator NrdR | 0.52 | PagCFBP13516_RS21080 | | alkene reductase | — | — |
| Escherichia coli ECRC101 | 0.81 | MCAODC_27685 | nrdR | transcriptional regulator NrdR | 0.46 | MCAODC_17975 | nemA | N-ethylmaleimide reductase | low | > 87 |
| Escherichia coli BL21 | 0.81 | ECD_00361 | | Nrd regulon repressor | 0.46 | ECD_01620 | | chromate reductase, quinone reductase, FMN-linked; N-Ethylmaleimide reductase; old yellow enzyme | low | > 61 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.81 | OHPLBJKB_03263 | | Transcriptional repressor NrdR | 0.46 | OHPLBJKB_02075 | | N-ethylmaleimide reductase | low | > 74 |
| Escherichia coli ECOR38 | 0.81 | HEPCGN_07085 | nrdR | transcriptional regulator NrdR | 0.46 | HEPCGN_05820 | nemA | N-ethylmaleimide reductase | low | > 88 |
| Escherichia coli ECRC102 | 0.81 | NIAGMN_06515 | nrdR | transcriptional regulator NrdR | 0.46 | NIAGMN_00630 | nemA | N-ethylmaleimide reductase | low | > 80 |
| Escherichia coli Nissle 1917 | 0.81 | ECOLIN_RS02500 | | transcriptional regulator NrdR | 0.46 | ECOLIN_RS09200 | | N-ethylmaleimide reductase | low | > 55 |
| Escherichia coli ECRC100 | 0.81 | OKFHMN_08460 | nrdR | transcriptional regulator NrdR | 0.46 | OKFHMN_27435 | nemA | N-ethylmaleimide reductase | low | > 79 |
| Escherichia coli ECRC62 | 0.81 | BNILDI_22820 | nrdR | transcriptional regulator NrdR | 0.46 | BNILDI_16745 | nemA | N-ethylmaleimide reductase | — | — |
| Escherichia coli ECRC98 | 0.81 | JDDGAC_12115 | nrdR | transcriptional regulator NrdR | 0.46 | JDDGAC_02025 | nemA | N-ethylmaleimide reductase | low | > 87 |
| Escherichia fergusonii Becca | 0.81 | EFB2_03644 | | Transcriptional repressor NrdR | 0.46 | EFB2_02342 | | N-ethylmaleimide reductase | low | > 86 |
| Escherichia coli ECOR27 | 0.81 | NOLOHH_01405 | nrdR | transcriptional regulator NrdR | 0.46 | NOLOHH_17955 | nemA | N-ethylmaleimide reductase | low | > 75 |
| Escherichia coli ECRC99 | 0.81 | KEDOAH_19505 | nrdR | transcriptional regulator NrdR | 0.46 | KEDOAH_00675 | nemA | N-ethylmaleimide reductase | — | — |
| Escherichia coli BW25113 | 0.81 | b0413 | ybaD | hypothetical protein (NCBI) | 0.46 | b1650 | nemA | N-ethylmaleimide reductase, FMN-linked (NCBI) | — | — |
| Enterobacter asburiae PDN3 | 0.80 | EX28DRAFT_2557 | | transcriptional regulator NrdR | 0.59 | EX28DRAFT_1386 | | NADH:flavin oxidoreductases, Old Yellow Enzyme family | — | — |
| Enterobacter sp. TBS_079 | 0.80 | MPMX20_01005 | | Transcriptional repressor NrdR | 0.59 | MPMX20_02166 | | N-ethylmaleimide reductase | low | > 85 |
| Rahnella sp. WP5 | 0.80 | EX31_RS22120 | | transcriptional regulator NrdR | 0.47 | EX31_RS13805 | | alkene reductase | low | > 89 |
| Dickeya dianthicola 67-19 | 0.79 | HGI48_RS05560 | | transcriptional regulator NrdR | 0.45 | HGI48_RS12730 | | alkene reductase | low | > 71 |
| Dickeya dianthicola ME23 | 0.79 | DZA65_RS05885 | | transcriptional regulator NrdR | 0.45 | DZA65_RS04670 | | alkene reductase | low | > 75 |
| Dickeya dadantii 3937 | 0.79 | DDA3937_RS05500 | | transcriptional regulator NrdR | 0.37 | DDA3937_RS14735 | | alkene reductase | low | > 74 |
| Serratia liquefaciens MT49 | 0.79 | IAI46_04890 | | transcriptional regulator NrdR | 0.46 | IAI46_11280 | | alkene reductase | low | > 87 |
| Shewanella oneidensis MR-1 | 0.79 | SO3470 | | conserved hypothetical protein TIGR00244 (NCBI ptt file) | 0.68 | SO4153 | | N-ethylmaleimide reductase, putative (NCBI ptt file) | low | > 76 |
| Shewanella loihica PV-4 | 0.79 | Shew_1186 | | transcriptional regulator NrdR (RefSeq) | 0.69 | Shew_0507 | | NADH:flavin oxidoreductase/NADH oxidase (RefSeq) | low | > 60 |
| Klebsiella michiganensis M5al | 0.79 | BWI76_RS06345 | | transcriptional regulator NrdR | 0.45 | BWI76_RS16475 | | alkene reductase | — | — |
| Erwinia amylovora T8 | 0.79 | OLJFJH_18095 | | transcriptional regulator NrdR | 0.49 | OLJFJH_03220 | | alkene reductase | low | > 58 |
| Pectobacterium carotovorum WPP14 | 0.79 | HER17_RS15965 | | transcriptional regulator NrdR | 0.43 | HER17_RS14310 | | alkene reductase | low | > 75 |
| Klebsiella pneumoniae MKP103 | 0.78 | KDGMDA_14435 | | transcriptional regulator NrdR | 0.46 | KDGMDA_23420 | | alkene reductase | low | > 94 |
| Klebsiella pneumoniae MRSN742743 | 0.78 | GJGHJB_03905 | nrdR | transcriptional regulator NrdR | 0.46 | GJGHJB_02192 | fadH | Alkene reductase | low | > 83 |
| Alteromonas macleodii MIT1002 | 0.76 | MIT1002_02701 | | Transcriptional repressor NrdR | 0.52 | MIT1002_01213 | | N-ethylmaleimide reductase | low | > 70 |
| Pseudomonas sp. S08-1 | 0.75 | OH686_15690 | | transcriptional regulator NrdR | 0.39 | OH686_06200 | | NADH:flavin , Old Yellow Enzyme family | low | > 80 |
| Pseudomonas stutzeri RCH2 | 0.74 | Psest_3553 | | transcriptional regulator NrdR | 0.52 | Psest_0753 | | NADH:flavin oxidoreductases, Old Yellow Enzyme family | — | — |
| Pseudomonas protegens RBAN4 | 0.73 | FABNJH_27800 | nrdR | transcriptional regulator NrdR | 0.42 | FABNJH_14595 | | N-ethylmaleimide reductase | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.73 | AO353_06720 | | NrdR family transcriptional regulator | 0.42 | AO353_28430 | | N-ethylmaleimide reductase | low | > 101 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.72 | Psyr_4463 | | Protein of unknown function DUF193 | 0.39 | Psyr_4053 | | NADH:flavin oxidoreductase/NADH oxidase | low | > 86 |
| Pseudomonas simiae WCS417 | 0.72 | PS417_25270 | | NrdR family transcriptional regulator | 0.49 | PS417_11190 | | oxidoreductase | low | > 88 |
| Pseudomonas syringae pv. syringae B728a | 0.72 | Psyr_4463 | | Protein of unknown function DUF193 | 0.39 | Psyr_4053 | | NADH:flavin oxidoreductase/NADH oxidase | low | > 86 |
| Pseudomonas orientalis W4I3 | 0.72 | QF045_RS27235 | | transcriptional regulator NrdR | 0.41 | QF045_RS09550 | | alkene reductase | low | > 93 |
| Pseudomonas fluorescens FW300-N2C3 | 0.72 | AO356_14925 | | NrdR family transcriptional regulator | 0.43 | AO356_25340 | | NADH:flavin oxidoreductase | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.72 | Pf1N1B4_2648 | | Ribonucleotide reductase transcriptional regulator NrdR | 0.43 | Pf1N1B4_4194 | | 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.72 | PfGW456L13_1312 | | Ribonucleotide reductase transcriptional regulator NrdR | 0.39 | PfGW456L13_4578 | | NADH:flavin oxidoreductases, Old Yellow Enzyme family | low | > 87 |
| Pseudomonas segetis P6 | 0.72 | ACVTMO_RS04900 | nrdR | transcriptional regulator NrdR | 0.40 | ACVTMO_RS18580 | | alkene reductase | low | > 75 |
| Pseudomonas sp. SVBP6 | 0.72 | COO64_RS15895 | nrdR | transcriptional regulator NrdR | 0.47 | COO64_RS09205 | | alkene reductase | low | > 91 |
| Pseudomonas aeruginosa PUPa3 | 0.72 | NPBIFN_00905 | nrdR | transcriptional regulator NrdR | 0.49 | NPBIFN_02080 | | Alkene reductase | low | > 101 |
| Pseudomonas sp. BP01 | 0.72 | JOY50_RS20130 | nrdR | transcriptional regulator NrdR | 0.45 | JOY50_RS12375 | | alkene reductase | — | — |
| Pseudomonas aeruginosa PA14 | 0.72 | IKLFDK_20915 | | transcriptional regulator NrdR | 0.49 | IKLFDK_14895 | | alkene reductase | low | > 98 |
| Pseudomonas aeruginosa MRSN321 | 0.72 | PFGADD_00900 | nrdR | transcriptional regulator NrdR | 0.49 | PFGADD_02041 | | Alkene reductase | low | > 99 |
| Pseudomonas putida KT2440 | 0.72 | PP_0513 | | DNA-binding transcriptional repressor NrdR-Zn2+-ATP/dATP | 0.50 | PP_2486 | | NADH-dependent flavin oxidoreductase, Oye family | low | > 96 |
| Pseudomonas sp. DMC3 | 0.72 | GFF3826 | | Transcriptional repressor NrdR | 0.49 | GFF2798 | | N-ethylmaleimide reductase | low | > 89 |
| Pseudomonas fluorescens SBW25 | 0.71 | PFLU_RS26905 | | transcriptional regulator NrdR | 0.49 | PFLU_RS11775 | | alkene reductase | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.71 | PFLU_RS26905 | | transcriptional regulator NrdR | 0.49 | PFLU_RS11775 | | alkene reductase | low | > 109 |
| Pseudomonas lactucae CFBP13502 | 0.71 | GEMAOFIL_05159 | | Transcriptional repressor NrdR | 0.48 | GEMAOFIL_02538 | | N-ethylmaleimide reductase | low | > 96 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.69 | GFF4317 | | Ribonucleotide reductase transcriptional regulator NrdR | 0.47 | GFF3624 | | N-ethylmaleimide reductase (EC 1.-.-.-) | low | > 78 |
| Acinetobacter baumannii LAC-4 | 0.61 | RR41_RS17860 | | transcriptional regulator NrdR | 0.46 | RR41_RS16240 | | alkene reductase | low | > 55 |
| Acinetobacter radioresistens SK82 | 0.60 | MPMX26_00151 | | Transcriptional repressor NrdR | 0.46 | MPMX26_00886 | | N-ethylmaleimide reductase | low | > 36 |
| Herbaspirillum seropedicae SmR1 | 0.59 | HSERO_RS06145 | | NrdR family transcriptional regulator | 0.43 | HSERO_RS15610 | | NADH:flavin oxidoreductase | low | > 78 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.58 | Xcc-8004.4397.1 | | Ribonucleotide reductase transcriptional regulator NrdR | 0.40 | Xcc-8004.3623.1 | | 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) | — | — |
| Methylophilus sp. DMC18 | 0.55 | GFF73 | | Transcriptional repressor NrdR | 0.43 | GFF937 | | N-ethylmaleimide reductase | low | > 43 |
| Cupriavidus basilensis FW507-4G11 | 0.54 | RR42_RS15490 | | NrdR family transcriptional regulator | 0.47 | RR42_RS06385 | | N-ethylmaleimide reductase | low | > 128 |
| Ralstonia solanacearum GMI1000 | 0.52 | RS_RS03665 | | transcriptional regulator NrdR | 0.48 | RS_RS06020 | | alkene reductase | low | > 80 |
| Ralstonia solanacearum IBSBF1503 | 0.52 | RALBFv3_RS12890 | | transcriptional regulator NrdR | 0.40 | RALBFv3_RS20595 | | alkene reductase | low | > 76 |
| Ralstonia solanacearum PSI07 | 0.52 | RPSI07_RS20335 | | transcriptional regulator NrdR | 0.48 | RPSI07_RS18165 | | alkene reductase | low | > 81 |
| Ralstonia solanacearum UW163 | 0.52 | UW163_RS00675 | | transcriptional regulator NrdR | 0.40 | UW163_RS18580 | | alkene reductase | — | — |
| Ralstonia sp. UNC404CL21Col | 0.52 | ABZR87_RS08950 | | transcriptional regulator NrdR | 0.47 | ABZR87_RS10850 | | alkene reductase | low | > 80 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.51 | H281DRAFT_04727 | | transcriptional repressor NrdR | 0.45 | H281DRAFT_06090 | | N-ethylmaleimide reductase | low | > 103 |
| Paraburkholderia graminis OAS925 | 0.51 | ABIE53_000889 | | transcriptional repressor NrdR | 0.48 | ABIE53_001750 | | N-ethylmaleimide reductase | low | > 113 |
| Paraburkholderia sabiae LMG 24235 | 0.51 | QEN71_RS26230 | | transcriptional regulator NrdR | 0.50 | QEN71_RS38950 | | alkene reductase | low | > 153 |
| Burkholderia phytofirmans PsJN | 0.51 | BPHYT_RS03730 | | transcriptional repressor NrdR | 0.45 | BPHYT_RS27240 | | N-ethylmaleimide reductase | low | > 109 |
| Dechlorosoma suillum PS | 0.51 | Dsui_1266 | | transcriptional regulator NrdR | 0.40 | Dsui_1877 | | NADH:flavin oxidoreductase | low | > 51 |
| Magnetospirillum magneticum AMB-1 | 0.49 | AMB_RS10475 | | transcriptional regulator NrdR | 0.37 | AMB_RS16690 | | alkene reductase | low | > 64 |
| Azospirillum brasilense Sp245 | 0.49 | AZOBR_RS10020 | | NrdR family transcriptional regulator | 0.41 | AZOBR_RS04305 | | 1 2-oxophytodienoate reductase | — | — |
| Variovorax sp. SCN45 | 0.49 | GFF561 | | Ribonucleotide reductase transcriptional regulator NrdR | 0.42 | GFF3328 | | NADH:flavin oxidoreductases, Old Yellow Enzyme family | low | > 127 |
| Variovorax sp. OAS795 | 0.49 | ABID97_RS17895 | | transcriptional regulator NrdR | 0.41 | ABID97_RS02870 | | alkene reductase | low | > 91 |
| Azospirillum sp. SherDot2 | 0.49 | MPMX19_00728 | | Transcriptional repressor NrdR | 0.44 | MPMX19_04479 | | N-ethylmaleimide reductase | low | > 112 |
| Castellaniella sp019104865 MT123 | 0.47 | ABCV34_RS10550 | | transcriptional regulator NrdR | 0.42 | ABCV34_RS07505 | | alkene reductase | low | > 48 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.47 | GFF5153 | | Ribonucleotide reductase transcriptional regulator NrdR | 0.56 | GFF2159 | | N-ethylmaleimide reductase | low | > 90 |
| Rhodospirillum rubrum S1H | 0.46 | Rru_A1826 | | Protein of unknown function DUF193 (NCBI) | 0.38 | Rru_A0475 | | NADH:flavin oxidoreductase/NADH oxidase (NCBI) | — | — |
| Sinorhizobium meliloti 1021 | 0.45 | SMc01771 | | transcriptional regulator NrdR | 0.42 | SMc01227 | | glycerol trinitrate (GTN) reductase | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.45 | Ga0059261_1985 | | transcriptional regulator NrdR | 0.37 | Ga0059261_2330 | | NADH:flavin oxidoreductases, Old Yellow Enzyme family | low | > 68 |
| Agrobacterium fabrum C58 | 0.45 | Atu1166 | | hypothetical protein | 0.44 | Atu5445 | | oxidoreductase | — | — |
| Rhodopseudomonas palustris CGA009 | 0.45 | TX73_014120 | | transcriptional regulator NrdR | 0.42 | TX73_022825 | | alkene reductase | — | — |
| Acidovorax sp. GW101-3H11 | 0.44 | Ac3H11_2922 | | Ribonucleotide reductase transcriptional regulator NrdR | 0.40 | Ac3H11_4975 | | Oxidoreductase, FMN-binding | — | — |
| Rhizobium sp. OAE497 | 0.43 | ABIE40_RS06720 | | transcriptional regulator NrdR | 0.41 | ABIE40_RS12885 | | alkene reductase | low | > 107 |
| Bosea sp. OAE506 | 0.42 | ABIE41_RS19765 | | transcriptional regulator NrdR | 0.39 | ABIE41_RS08040 | | alkene reductase | — | — |
| Xanthobacter sp. DMC5 | 0.42 | GFF576 | | Transcriptional repressor NrdR | 0.43 | GFF2396 | | N-ethylmaleimide reductase | — | — |
| Sphingobium sp. HT1-2 | 0.42 | GFF3899 | | Ribonucleotide reductase transcriptional regulator NrdR | 0.37 | GFF3259 | | NADH:flavin oxidoreductases, Old Yellow Enzyme family | — | — |
| Synechococcus elongatus PCC 7942 | 0.41 | Synpcc7942_0695 | | hypothetical protein | 0.44 | Synpcc7942_0473 | | NADH:flavin oxidoreductase Old Yellow Enzyme family-like | low | > 38 |
Not shown: 21 genomes with orthologs for CSW01_11565 only; 4 genomes with orthologs for CSW01_19080 only