Conservation of cofitness between CSW01_04470 and CSW01_18760 in Vibrio cholerae E7946 ATCC 55056

83 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_04470 phosphoribosylformylglycinamidine synthase 1.0 CSW01_18760 dihydroorotase 0.57 10
Serratia liquefaciens MT49 0.76 IAI46_19475 phosphoribosylformylglycinamidine synthase 0.57 IAI46_09740 dihydroorotase low > 87
Escherichia coli BL21 0.76 ECD_02449 phosphoribosylformyl-glycineamide synthetase 0.55 ECD_01058 dihydro-orotase 0.83 12
Escherichia coli BW25113 0.76 b2557 purL phosphoribosylformylglycinamidine synthase (NCBI) 0.55 b1062 pyrC dihydroorotase (NCBI) 0.92 8
Escherichia coli ECOR27 0.76 NOLOHH_13145 purL phosphoribosylformylglycinamidine synthase 0.55 NOLOHH_21260 pyrC dihydroorotase 0.96 8
Escherichia coli HS(pFamp)R (ATCC 700891) 0.76 OHPLBJKB_01150 Phosphoribosylformylglycinamidine synthase 0.55 OHPLBJKB_02603 Dihydroorotase 0.47 11
Escherichia fergusonii Becca 0.76 EFB2_01339 Phosphoribosylformylglycinamidine synthase 0.55 EFB2_02912 Dihydroorotase low > 86
Escherichia coli ECRC102 0.76 NIAGMN_19240 purL phosphoribosylformylglycinamidine synthase 0.55 NIAGMN_24100 pyrC dihydroorotase 0.82 37
Escherichia coli ECRC99 0.76 KEDOAH_06750 purL phosphoribosylformylglycinamidine synthase 0.55 KEDOAH_24025 pyrC dihydroorotase — —
Escherichia coli ECRC98 0.76 JDDGAC_25135 purL phosphoribosylformylglycinamidine synthase 0.55 JDDGAC_07390 pyrC dihydroorotase low > 87
Escherichia coli ECRC100 0.76 OKFHMN_21470 purL phosphoribosylformylglycinamidine synthase 0.55 OKFHMN_03730 pyrC dihydroorotase 0.94 8
Escherichia coli ECRC101 0.76 MCAODC_12000 purL phosphoribosylformylglycinamidine synthase 0.55 MCAODC_23090 pyrC dihydroorotase low > 87
Escherichia coli ECRC62 0.76 BNILDI_11945 purL phosphoribosylformylglycinamidine synthase 0.55 BNILDI_19420 pyrC dihydroorotase 0.96 8
Escherichia coli Nissle 1917 0.76 ECOLIN_RS14470 phosphoribosylformylglycinamidine synthase 0.55 ECOLIN_RS06160 dihydroorotase 0.81 6
Enterobacter asburiae PDN3 0.76 EX28DRAFT_0092 phosphoribosylformylglycinamidine synthase, single chain form 0.57 EX28DRAFT_1869 dihydroorotase (EC 3.5.2.3) — —
Escherichia coli ECOR38 0.76 HEPCGN_20615 purL phosphoribosylformylglycinamidine synthase 0.55 HEPCGN_23760 pyrC dihydroorotase 0.94 11
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.75 GFF2459 Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) 0.53 GFF3342 Dihydroorotase (EC 3.5.2.3) low > 78
Enterobacter sp. TBS_079 0.75 MPMX20_03426 Phosphoribosylformylglycinamidine synthase 0.57 MPMX20_01741 Dihydroorotase 0.83 43
Klebsiella pneumoniae MKP103 0.75 KDGMDA_28395 phosphoribosylformylglycinamidine synthase 0.56 KDGMDA_18610 dihydroorotase low > 95
Rahnella sp. WP5 0.75 EX31_RS21895 phosphoribosylformylglycinamidine synthase 0.55 EX31_RS24385 dihydroorotase 0.90 48
Pantoea agglomerans CFBP13505 P0401 0.75 PagCFBP13505_RS14820 phosphoribosylformylglycinamidine synthase 0.55 PagCFBP13505_RS05115 dihydroorotase low > 74
Pantoea sp. MT58 0.75 IAI47_04930 phosphoribosylformylglycinamidine synthase 0.54 IAI47_12215 dihydroorotase 0.98 6
Erwinia amylovora T8 0.75 OLJFJH_10305 phosphoribosylformylglycinamidine synthase 0.56 OLJFJH_15670 dihydroorotase low > 58
Dickeya dadantii 3937 0.75 DDA3937_RS15655 phosphoribosylformylglycinamidine synthase 0.56 DDA3937_RS13170 dihydroorotase 0.86 13
Klebsiella michiganensis M5al 0.74 BWI76_RS21265 phosphoribosylformylglycinamidine synthase 0.55 BWI76_RS10990 dihydroorotase 0.54 88
Dickeya dianthicola ME23 0.74 DZA65_RS16830 phosphoribosylformylglycinamidine synthase 0.55 DZA65_RS13710 dihydroorotase 0.69 31
Dickeya dianthicola 67-19 0.74 HGI48_RS15750 phosphoribosylformylglycinamidine synthase 0.55 HGI48_RS13235 dihydroorotase 0.93 2
Pectobacterium carotovorum WPP14 0.74 HER17_RS05910 phosphoribosylformylglycinamidine synthase 0.56 HER17_RS08600 dihydroorotase 0.97 5
Shewanella oneidensis MR-1 0.73 SO3287 purL phosphoribosylformylglycinamidine synthase (NCBI ptt file) 0.75 SO3695 pyrC dihydroorotase, homodimeric type (NCBI ptt file) 0.87 26
Erwinia tracheiphila HP pepo 2.2 0.73 IJEDHG_02970 Phosphoribosylformylglycinamidine synthase 0.57 IJEDHG_20990 pyrC dihydroorotase 0.83 21
Shewanella sp. ANA-3 0.73 Shewana3_1240 phosphoribosylformylglycinamidine synthase (RefSeq) 0.77 Shewana3_3263 dihydroorotase (RefSeq) 0.83 65
Erwinia tracheiphila SCR3 0.73 LU632_RS17975 purL phosphoribosylformylglycinamidine synthase 0.57 LU632_RS10340 pyrC dihydroorotase 0.97 5
Shewanella amazonensis SB2B 0.72 Sama_2350 phosphoribosylformylglycinamidine synthase (RefSeq) 0.77 Sama_2870 dihydroorotase (RefSeq) low > 62
Shewanella loihica PV-4 0.72 Shew_1301 phosphoribosylformylglycinamidine synthase (RefSeq) 0.74 Shew_0728 dihydroorotase (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.71 MIT1002_01027 Phosphoribosylformylglycinamidine synthase 0.61 MIT1002_03750 Dihydroorotase — —
Pseudomonas aeruginosa PUPa3 0.67 DQ20_RS42970 purL;go_function=phosphoribosylformylglycinamidine phosphoribosylformylglycinamidine synthase 0.66 DQ20_RS41770 pyrC;go_function=dihydroorotase dihydroorotase — —
Pseudomonas aeruginosa PA14 0.67 IKLFDK_19210 phosphoribosylformylglycinamidine synthase 0.66 IKLFDK_18005 dihydroorotase — —
Pseudomonas aeruginosa MRSN321 0.67 DY961_RS14145 purL;go_function=phosphoribosylformylglycinamidine phosphoribosylformylglycinamidine synthase 0.66 DY961_RS15380 pyrC;go_function=dihydroorotase dihydroorotase — —
Pseudomonas sp. SVBP6 0.67 COO64_RS04695 purL phosphoribosylformylglycinamidine synthase 0.67 COO64_RS16860 pyrC dihydroorotase — —
Pseudomonas putida KT2440 0.67 PP_1037 Phosphoribosylformylglycinamidine synthase 0.66 PP_1086 dihydroorotase — —
Pseudomonas sp. BP01 0.67 JOY50_RS11525 purL phosphoribosylformylglycinamidine synthase 0.66 JOY50_RS14925 pyrC dihydroorotase — —
Pseudomonas segetis P6 0.67 MPMX49_01557 Phosphoribosylformylglycinamidine synthase 0.67 MPMX49_01445 Dihydroorotase — —
Pseudomonas stutzeri RCH2 0.67 Psest_3159 phosphoribosylformylglycinamidine synthase, single chain form 0.66 Psest_3123 dihydroorotase, homodimeric type 0.65 7
Pseudomonas sp. S08-1 0.67 OH686_17630 phosphoribosylformylglycinamidine synthase 0.66 OH686_03940 dihydroorotase, homodimeric type — —
Pseudomonas syringae pv. syringae B728a 0.67 Psyr_1269 phosphoribosylformylglycinamidine synthase 0.67 Psyr_3894 dihydroorotase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.67 Psyr_1269 phosphoribosylformylglycinamidine synthase 0.67 Psyr_3894 dihydroorotase — —
Pseudomonas simiae WCS417 0.67 PS417_23020 phosphoribosylformylglycinamidine synthase 0.66 PS417_05630 dihydroorotase — —
Pseudomonas fluorescens SBW25 0.66 PFLU_RS24685 phosphoribosylformylglycinamidine synthase 0.66 PFLU_RS05715 dihydroorotase — —
Pseudomonas fluorescens SBW25-INTG 0.66 PFLU_RS24685 phosphoribosylformylglycinamidine synthase 0.66 PFLU_RS05715 dihydroorotase — —
Pseudomonas sp. DMC3 0.66 GFF1962 Phosphoribosylformylglycinamidine synthase 0.67 GFF5094 Dihydroorotase — —
Pseudomonas sp. RS175 0.66 PFR28_03518 Phosphoribosylformylglycinamidine synthase 0.67 PFR28_03355 Dihydroorotase — —
Pseudomonas orientalis W4I3 0.66 QF045_RS25230 phosphoribosylformylglycinamidine synthase 0.66 QF045_RS08555 dihydroorotase — —
Pseudomonas lactucae CFBP13502 0.66 GEMAOFIL_04757 Phosphoribosylformylglycinamidine synthase 0.66 GEMAOFIL_01313 Dihydroorotase — —
Pseudomonas fluorescens FW300-N2C3 0.66 AO356_17520 phosphoribosylformylglycinamidine synthase 0.66 AO356_18315 dihydroorotase — —
Pseudomonas fluorescens FW300-N1B4 0.66 Pf1N1B4_887 Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) 0.67 Pf1N1B4_744 Dihydroorotase (EC 3.5.2.3) — —
Pseudomonas fluorescens FW300-N2E2 0.66 Pf6N2E2_5432 Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) 0.66 Pf6N2E2_5588 Dihydroorotase (EC 3.5.2.3) — —
Pseudomonas fluorescens FW300-N2E3 0.66 AO353_04485 phosphoribosylformylglycinamidine synthase 0.67 AO353_04115 dihydroorotase — —
Pseudomonas fluorescens GW456-L13 0.66 PfGW456L13_4835 Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) 0.67 PfGW456L13_1747 Dihydroorotase (EC 3.5.2.3) — —
Marinobacter adhaerens HP15 0.65 HP15_1239 phosphoribosylformylglycinamidine synthase 0.65 HP15_1216 dihydroorotase, homodimeric type — —
Kangiella aquimarina DSM 16071 0.64 B158DRAFT_2244 phosphoribosylformylglycinamidine synthase, single chain form 0.67 B158DRAFT_1241 dihydroorotase (EC 3.5.2.3) — —
Methylophilus sp. DMC18 0.62 GFF809 Phosphoribosylformylglycinamidine synthase 0.61 GFF2451 Dihydroorotase — —
Herbaspirillum seropedicae SmR1 0.58 HSERO_RS11190 phosphoribosylformylglycinamidine synthase 0.62 HSERO_RS19235 dihydroorotase — —
Cupriavidus basilensis FW507-4G11 0.57 RR42_RS09140 phosphoribosylformylglycinamidine synthase 0.62 RR42_RS02610 dihydroorotase — —
Dechlorosoma suillum PS 0.56 Dsui_2892 phosphoribosylformylglycinamidine synthase, single chain form 0.60 Dsui_0250 dihydroorotase, homodimeric type — —
Acinetobacter baumannii LAC-4 0.56 RR41_RS04700 phosphoribosylformylglycinamidine synthase 0.59 RR41_RS09355 dihydroorotase — —
Burkholderia phytofirmans PsJN 0.56 BPHYT_RS09515 phosphoribosylformylglycinamidine synthase 0.61 BPHYT_RS16675 dihydroorotase 0.85 6
Acinetobacter radioresistens SK82 0.56 MPMX26_02183 Phosphoribosylformylglycinamidine synthase 0.59 MPMX26_02262 Dihydroorotase — —
Paraburkholderia bryophila 376MFSha3.1 0.56 H281DRAFT_00909 phosphoribosylformylglycinamidine synthase 0.61 H281DRAFT_04265 dihydroorotase — —
Paraburkholderia sabiae LMG 24235 0.55 QEN71_RS21920 phosphoribosylformylglycinamidine synthase 0.61 QEN71_RS26855 dihydroorotase low > 153
Paraburkholderia graminis OAS925 0.55 ABIE53_002141 phosphoribosylformylglycinamidine synthase 0.62 ABIE53_003505 dihydroorotase — —
Ralstonia solanacearum PSI07 0.54 RPSI07_RS16190 phosphoribosylformylglycinamidine synthase 0.64 RPSI07_RS21625 dihydroorotase — —
Ralstonia solanacearum GMI1000 0.54 RS_RS08710 phosphoribosylformylglycinamidine synthase 0.65 RS_RS02420 dihydroorotase — —
Ralstonia sp. UNC404CL21Col 0.54 ABZR87_RS12730 phosphoribosylformylglycinamidine synthase 0.65 ABZR87_RS07550 dihydroorotase — —
Ralstonia solanacearum UW163 0.53 UW163_RS14595 phosphoribosylformylglycinamidine synthase 0.64 UW163_RS01995 dihydroorotase — —
Ralstonia solanacearum IBSBF1503 0.53 RALBFv3_RS01285 phosphoribosylformylglycinamidine synthase 0.64 RALBFv3_RS11590 dihydroorotase — —
Rhodanobacter sp. FW510-T8 0.53 OKGIIK_11505 purL phosphoribosylformylglycinamidine synthase 0.57 OKGIIK_12970 pyrC dihydroorotase — —
Rhodanobacter denitrificans MT42 0.53 LRK55_RS04500 phosphoribosylformylglycinamidine synthase 0.57 LRK55_RS10600 dihydroorotase low > 63
Variovorax sp. SCN45 0.53 GFF1324 Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) 0.59 GFF4557 Dihydroorotase (EC 3.5.2.3) low > 127
Rhodanobacter denitrificans FW104-10B01 0.53 LRK54_RS04720 phosphoribosylformylglycinamidine synthase 0.59 LRK54_RS10900 dihydroorotase — —
Variovorax sp. OAS795 0.53 ABID97_RS15675 phosphoribosylformylglycinamidine synthase 0.59 ABID97_RS06040 dihydroorotase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.52 GFF4566 Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) 0.61 GFF523 Dihydroorotase (EC 3.5.2.3) — —
Acidovorax sp. GW101-3H11 0.52 Ac3H11_539 Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) 0.62 Ac3H11_1963 Dihydroorotase (EC 3.5.2.3) — —
Rhodanobacter sp000427505 FW510-R12 0.52 LRK53_RS05295 phosphoribosylformylglycinamidine synthase 0.59 LRK53_RS03690 dihydroorotase low > 59
Castellaniella sp019104865 MT123 0.50 ABCV34_RS04940 phosphoribosylformylglycinamidine synthase 0.57 ABCV34_RS09730 dihydroorotase — —

Not shown: 14 genomes with orthologs for CSW01_04470 only; 8 genomes with orthologs for CSW01_18760 only