Conservation of cofitness between CSW01_02430 and CSW01_05825 in Vibrio cholerae E7946 ATCC 55056

76 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02430 non-canonical purine NTP pyrophosphatase 1.0 CSW01_05825 transcriptional regulator HexR 0.54 9
Escherichia coli ECRC99 0.66 KEDOAH_08900 rdgB XTP/dITP diphosphatase 0.73 KEDOAH_01780 hexR DNA-binding transcriptional regulator HexR
Escherichia coli ECRC98 0.66 JDDGAC_22870 rdgB XTP/dITP diphosphatase 0.73 JDDGAC_00900 hexR DNA-binding transcriptional regulator HexR low > 87
Escherichia coli ECRC100 0.66 OKFHMN_19240 rdgB XTP/dITP diphosphatase 0.73 OKFHMN_26325 hexR DNA-binding transcriptional regulator HexR low > 79
Escherichia coli ECRC102 0.66 NIAGMN_17005 rdgB XTP/dITP diphosphatase 0.73 NIAGMN_01735 hexR DNA-binding transcriptional regulator HexR low > 80
Escherichia coli Nissle 1917 0.66 ECOLIN_RS16430 XTP/dITP diphosphatase 0.73 ECOLIN_RS10325 DNA-binding transcriptional regulator HexR low > 55
Escherichia fergusonii Becca 0.66 EFB2_00948 dITP/XTP pyrophosphatase 0.73 EFB2_02089 HTH-type transcriptional regulator HexR low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.66 OHPLBJKB_00762 dITP/XTP pyrophosphatase 0.73 OHPLBJKB_01875 HTH-type transcriptional regulator HexR low > 74
Escherichia coli ECOR27 0.66 NOLOHH_11110 rdgB XTP/dITP diphosphatase 0.73 NOLOHH_16840 hexR DNA-binding transcriptional regulator HexR low > 76
Enterobacter asburiae PDN3 0.66 EX28DRAFT_2992 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.74 EX28DRAFT_0703 transcriptional regulator, RpiR family low > 76
Escherichia coli ECRC62 0.66 BNILDI_09690 rdgB XTP/dITP diphosphatase 0.73 BNILDI_15635 hexR DNA-binding transcriptional regulator HexR low > 75
Enterobacter sp. TBS_079 0.65 MPMX20_03812 dITP/XTP pyrophosphatase 0.74 MPMX20_02758 HTH-type transcriptional regulator HexR low > 85
Escherichia coli BW25113 0.65 b2954 yggV putative deoxyribonucleotide triphosphate pyrophosphatase (NCBI) 0.73 b1853 yebK predicted DNA-binding transcriptional regulator (NCBI) low > 76
Escherichia coli ECOR38 0.65 HEPCGN_18545 rdgB XTP/dITP diphosphatase 0.73 HEPCGN_04730 hexR DNA-binding transcriptional regulator HexR low > 88
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.65 GFF3057 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.72 GFF1632 Phosphogluconate repressor HexR, RpiR family low > 78
Rahnella sp. WP5 0.65 EX31_RS02705 XTP/dITP diphosphatase 0.76 EX31_RS10635 MurR/RpiR family transcriptional regulator low > 89
Escherichia coli BL21 0.65 ECD_02784 dITP/XTP pyrophosphatase 0.73 ECD_01824 putative DNA-binding transcriptional regulator
Klebsiella pneumoniae MKP103 0.65 KDGMDA_04630 XTP/dITP diphosphatase 0.72 KDGMDA_25375 transcriptional regulator HexR low > 95
Escherichia coli ECRC101 0.65 MCAODC_09760 rdgB XTP/dITP diphosphatase 0.73 MCAODC_19080 hexR DNA-binding transcriptional regulator HexR low > 88
Klebsiella michiganensis M5al 0.65 BWI76_RS24115 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.72 BWI76_RS18110 transcriptional regulator HexR low > 92
Serratia liquefaciens MT49 0.65 IAI46_21430 XTP/dITP diphosphatase 0.78 IAI46_14580 MurR/RpiR family transcriptional regulator low > 86
Dickeya dianthicola ME23 0.64 DZA65_RS18455 XTP/dITP diphosphatase 0.75 DZA65_RS10575 MurR/RpiR family transcriptional regulator low > 75
Pantoea sp. MT58 0.64 IAI47_03585 XTP/dITP diphosphatase 0.63 IAI47_08490 MurR/RpiR family transcriptional regulator low > 76
Dickeya dadantii 3937 0.64 DDA3937_RS17320 XTP/dITP diphosphatase 0.75 DDA3937_RS10130 MurR/RpiR family transcriptional regulator low > 74
Dickeya dianthicola 67-19 0.63 HGI48_RS17365 XTP/dITP diphosphatase 0.75 HGI48_RS10160 MurR/RpiR family transcriptional regulator low > 71
Pantoea agglomerans CFBP13505 P0401 0.61 PagCFBP13505_RS16110 XTP/dITP diphosphatase 0.61 PagCFBP13505_RS02370 transcriptional regulator HexR low > 74
Erwinia tracheiphila HP pepo 2.2 0.61 IJEDHG_03460 rdgB XTP/dITP diphosphatase 0.64 IJEDHG_22185 transcriptional regulator HexR low > 61
Erwinia tracheiphila SCR3 0.61 LU632_RS05450 XTP/dITP diphosphatase 0.64 LU632_RS13365 MurR/RpiR family transcriptional regulator low > 74
Alteromonas macleodii MIT1002 0.60 MIT1002_00940 dITP/XTP pyrophosphatase 0.73 MIT1002_02408 putative HTH-type transcriptional regulator YbbH
Shewanella loihica PV-4 0.60 Shew_1132 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase (RefSeq) 0.78 Shew_2049 DNA-binding transcriptional regulator HexR (RefSeq)
Pectobacterium carotovorum WPP14 0.59 HER17_RS03790 XTP/dITP diphosphatase 0.77 HER17_RS11785 MurR/RpiR family transcriptional regulator low > 75
Shewanella sp. ANA-3 0.59 Shewana3_1189 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase (RefSeq) 0.77 Shewana3_2152 DNA-binding transcriptional regulator HexR (RefSeq) low > 73
Shewanella oneidensis MR-1 0.58 SO3358 HAM1 protein (NCBI ptt file) 0.77 SO2490 transcriptional regulator, RpiR family (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.56 Sama_2482 Ham1-like protein (RefSeq) 0.77 Sama_1813 DNA-binding transcriptional regulator HexR (RefSeq) low > 62
Marinobacter adhaerens HP15 0.56 HP15_281 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.55 HP15_2180 transcriptional regulator, RpiR family protein low > 73
Pseudomonas syringae pv. syringae B728a ΔmexB 0.54 Psyr_0472 Ham1-like protein 0.56 Psyr_1119 Helix-turn-helix protein RpiR:Sugar isomerase (SIS) low > 86
Pseudomonas syringae pv. syringae B728a 0.54 Psyr_0472 Ham1-like protein 0.56 Psyr_1119 Helix-turn-helix protein RpiR:Sugar isomerase (SIS) low > 86
Pseudomonas fluorescens FW300-N2C3 0.53 AO356_13395 non-canonical purine NTP pyrophosphatase 0.57 AO356_05165 transcriptional regulator low > 104
Pseudomonas segetis P6 0.53 MPMX49_00604 dITP/XTP pyrophosphatase 0.57 MPMX49_02832 HTH-type transcriptional regulator HexR low > 75
Pseudomonas sp. RS175 0.53 PFR28_04248 dITP/XTP pyrophosphatase 0.57 PFR28_00572 HTH-type transcriptional regulator HexR low > 88
Pseudomonas fluorescens FW300-N2E2 0.52 Pf6N2E2_4594 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.57 Pf6N2E2_2886 Phosphogluconate repressor HexR, RpiR family low > 103
Pseudomonas sp. SVBP6 0.52 COO64_RS12970 rdgB RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.58 COO64_RS04585 hexR DNA-binding transcriptional regulator HexR low > 93
Pseudomonas lactucae CFBP13502 0.52 GEMAOFIL_05488 dITP/XTP pyrophosphatase 0.57 GEMAOFIL_04559 HTH-type transcriptional regulator HexR low > 93
Pseudomonas simiae WCS417 0.52 PS417_26755 nucleoside-triphosphate diphosphatase 0.57 PS417_22115 transcriptional regulator low > 88
Pseudomonas sp. DMC3 0.52 GFF215 dITP/XTP pyrophosphatase 0.58 GFF5141 HTH-type transcriptional regulator HexR low > 89
Pseudomonas putida KT2440 0.52 PP_5100 dITP/XTP pyrophosphatase 0.57 PP_1021 DNA-binding transcriptional regulator low > 96
Pseudomonas aeruginosa PA14 0.52 IKLFDK_23490 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.55 IKLFDK_16180 HTH-type transcriptional regulator HexR low > 100
Pseudomonas sp. BP01 0.52 JOY50_RS20880 rdgB RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.57 JOY50_RS11445 hexR DNA-binding transcriptional regulator HexR low > 84
Pseudomonas fluorescens FW300-N2E3 0.51 AO353_08195 non-canonical purine NTP pyrophosphatase 0.57 AO353_03365 transcriptional regulator low > 101
Paraburkholderia bryophila 376MFSha3.1 0.51 H281DRAFT_04009 XTP/dITP diphosphohydrolase 0.33 H281DRAFT_04279 transcriptional regulator, RpiR family low > 103
Paraburkholderia sabiae LMG 24235 0.51 QEN71_RS03640 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.30 QEN71_RS26925 MurR/RpiR family transcriptional regulator low > 153
Pseudomonas fluorescens SBW25-INTG 0.51 PFLU_RS28400 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.57 PFLU_RS23730 MurR/RpiR family transcriptional regulator low > 109
Pseudomonas fluorescens SBW25 0.51 PFLU_RS28400 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.57 PFLU_RS23730 MurR/RpiR family transcriptional regulator low > 109
Pseudomonas fluorescens GW456-L13 0.51 PfGW456L13_1004 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.57 PfGW456L13_1900 Phosphogluconate repressor HexR, RpiR family low > 87
Paraburkholderia graminis OAS925 0.51 ABIE53_003235 XTP/dITP diphosphohydrolase 0.35 ABIE53_003518 RpiR family carbohydrate utilization transcriptional regulator low > 113
Pseudomonas fluorescens FW300-N1B4 0.51 Pf1N1B4_2335 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.57 Pf1N1B4_590 Phosphogluconate repressor HexR, RpiR family low > 87
Burkholderia phytofirmans PsJN 0.50 BPHYT_RS15330 nucleoside-triphosphate diphosphatase 0.34 BPHYT_RS16740 transcriptional regulator low > 109
Pseudomonas stutzeri RCH2 0.50 Psest_0277 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family 0.57 Psest_0851 Transcriptional regulators low > 67
Pseudomonas sp. S08-1 0.50 OH686_11015 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.58 OH686_02440 Phosphogluconate repressor HexR, RpiR family low > 80
Herbaspirillum seropedicae SmR1 0.48 HSERO_RS10660 nucleoside-triphosphate diphosphatase 0.32 HSERO_RS05505 transcriptional regulator low > 78
Ralstonia solanacearum UW163 0.45 UW163_RS10370 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.22 UW163_RS20950 MurR/RpiR family transcriptional regulator
Ralstonia solanacearum IBSBF1503 0.45 RALBFv3_RS03350 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.22 RALBFv3_RS18180 MurR/RpiR family transcriptional regulator low > 76
Ralstonia sp. UNC404CL21Col 0.45 ABZR87_RS15260 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.22 ABZR87_RS03145 MurR/RpiR family transcriptional regulator low > 80
Ralstonia solanacearum PSI07 0.44 RPSI07_RS13835 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.22 RPSI07_RS05455 MurR/RpiR family transcriptional regulator
Castellaniella sp019104865 MT123 0.44 ABCV34_RS03520 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.39 ABCV34_RS08655 SIS domain-containing protein low > 48
Ralstonia solanacearum GMI1000 0.43 RS_RS10835 non-canonical purine NTP pyrophosphatase 0.23 RS_RS22855 MurR/RpiR family transcriptional regulator low > 80
Cupriavidus basilensis FW507-4G11 0.43 RR42_RS04885 nucleoside-triphosphate diphosphatase 0.34 RR42_RS06120 transcriptional regulator low > 128
Hydrogenophaga sp. GW460-11-11-14-LB1 0.38 GFF3255 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.33 GFF1364 Phosphogluconate repressor HexR, RpiR family low > 90
Variovorax sp. SCN45 0.36 GFF2382 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.66) 0.20 GFF6715 Transcriptional regulator of RpiR family in catabolic operon low > 127
Variovorax sp. OAS795 0.35 ABID97_RS23635 non-canonical purine NTP pyrophosphatase 0.20 ABID97_RS22860 MurR/RpiR family transcriptional regulator low > 91
Acidovorax sp. GW101-3H11 0.35 Ac3H11_3671 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.34 Ac3H11_2055 Probable transcriptional regulator low > 79
Agrobacterium fabrum C58 0.32 Atu0326 putative deoxyribonucleotide triphosphate pyrophosphatase 0.25 Atu2598 transcriptional regulator, RpiR family
Phaeobacter inhibens DSM 17395 0.31 PGA1_c35040 nucleoside-triphosphatase RdgB 0.10 PGA1_c27130 putative HTH-type transcriptional regulator low > 62
Sinorhizobium meliloti 1021 0.30 SMc01146 deoxyribonucleotide triphosphate pyrophosphatase 0.38 SMc02460 hypothetical protein low > 103
Rhizobium sp. OAE497 0.29 ABIE40_RS01630 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.25 ABIE40_RS21410 MurR/RpiR family transcriptional regulator low > 107
Azospirillum sp. SherDot2 0.27 MPMX19_02575 dITP/XTP pyrophosphatase 0.33 MPMX19_05117 HTH-type transcriptional regulator HexR low > 112
Azospirillum brasilense Sp245 0.27 AZOBR_RS02200 nucleoside-triphosphate diphosphatase 0.35 AZOBR_RS30190 transcriptional regulator low > 97

Not shown: 43 genomes with orthologs for CSW01_02430 only; 0 genomes with orthologs for CSW01_05825 only