Conservation of cofitness between CSW01_13305 and CSW01_02450 in Vibrio cholerae E7946 ATCC 55056

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_13305 shikimate kinase 1.0 CSW01_02450 pyrroline-5-carboxylate reductase 0.62 7
Serratia liquefaciens MT49 0.83 IAI46_23705 shikimate kinase AroK 0.69 IAI46_21415 pyrroline-5-carboxylate reductase — —
Klebsiella pneumoniae MKP103 0.82 KDGMDA_06915 shikimate kinase AroK 0.27 KDGMDA_14250 pyrroline-5-carboxylate reductase — —
Klebsiella pneumoniae MRSN742743 0.82 GJGHJB_00353 aroK shikimate kinase AroK 0.27 GJGHJB_03942 proC pyrroline-5-carboxylate reductase low > 83
Enterobacter asburiae PDN3 0.82 EX28DRAFT_4152 shikimate kinase (EC 2.7.1.71) 0.27 EX28DRAFT_2585 pyrroline-5-carboxylate reductase low > 76
Enterobacter sp. TBS_079 0.82 MPMX20_04279 Shikimate kinase 1 0.27 MPMX20_00976 Pyrroline-5-carboxylate reductase 0.32 20
Klebsiella michiganensis M5al 0.82 BWI76_RS26090 shikimate kinase 0.27 BWI76_RS06170 pyrroline-5-carboxylate reductase — —
Erwinia amylovora T8 0.82 OLJFJH_04095 shikimate kinase AroK 0.26 OLJFJH_18285 pyrroline-5-carboxylate reductase — —
Pectobacterium carotovorum WPP14 0.82 HER17_RS01775 shikimate kinase AroK 0.69 HER17_RS03805 pyrroline-5-carboxylate reductase — —
Pantoea agglomerans CFBP13505 P0401 0.81 PagCFBP13516_RS01890 aroK shikimate kinase AroK 0.26 PagCFBP13516_RS15240 proC pyrroline-5-carboxylate reductase — —
Pantoea sp. MT58 0.81 IAI47_01890 shikimate kinase AroK 0.26 IAI47_14945 pyrroline-5-carboxylate reductase — —
Escherichia coli ECRC62 0.81 BNILDI_02620 aroK shikimate kinase AroK 0.27 BNILDI_22950 proC pyrroline-5-carboxylate reductase — —
Rahnella sp. WP5 0.81 EX31_RS04725 shikimate kinase AroK 0.65 EX31_RS02690 pyrroline-5-carboxylate reductase 0.79 27
Escherichia fergusonii Becca 0.81 EFB2_00438 Shikimate kinase 1 0.27 EFB2_03670 Pyrroline-5-carboxylate reductase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.81 OHPLBJKB_00313 Shikimate kinase 1 0.27 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase — —
Escherichia coli BL21 0.81 ECD_03242 shikimate kinase I 0.27 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding low > 61
Escherichia coli ECOR27 0.81 NOLOHH_08900 aroK shikimate kinase AroK 0.27 NOLOHH_01535 proC pyrroline-5-carboxylate reductase 0.24 44
Escherichia coli BW25113 0.81 b3390 aroK shikimate kinase I (NCBI) 0.27 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 0.45 49
Escherichia coli ECOR38 0.81 HEPCGN_15930 aroK shikimate kinase AroK 0.27 HEPCGN_07250 proC pyrroline-5-carboxylate reductase low > 88
Escherichia coli Nissle 1917 0.81 ECOLIN_RS19365 shikimate kinase AroK 0.27 ECOLIN_RS02345 pyrroline-5-carboxylate reductase — —
Shewanella sp. ANA-3 0.79 Shewana3_3894 aroK shikimate kinase I (RefSeq) 0.56 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) — —
Shewanella amazonensis SB2B 0.79 Sama_3368 aroK shikimate kinase I (RefSeq) 0.50 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) — —
Shewanella oneidensis MR-1 0.79 SO0286 aroK shikimate kinase (NCBI ptt file) 0.57 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) — —
Shewanella loihica PV-4 0.78 Shew_0213 shikimate kinase I (RefSeq) 0.52 Shew_1136 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) — —
Alteromonas macleodii MIT1002 0.75 MIT1002_00448 Shikimate kinase 1 0.60 MIT1002_03062 Pyrroline-5-carboxylate reductase — —
Dickeya dianthicola 67-19 0.75 HGI48_RS19680 shikimate kinase AroK 0.68 HGI48_RS17350 pyrroline-5-carboxylate reductase — —
Dickeya dadantii 3937 0.75 DDA3937_RS19550 shikimate kinase AroK 0.68 DDA3937_RS17305 pyrroline-5-carboxylate reductase — —
Dickeya dianthicola ME23 0.75 DZA65_RS20765 shikimate kinase AroK 0.67 DZA65_RS18440 pyrroline-5-carboxylate reductase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.74 GFF629 Shikimate kinase I (EC 2.7.1.71) 0.26 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) low > 78
Kangiella aquimarina DSM 16071 0.67 B158DRAFT_0763 shikimate kinase (EC 2.7.1.71) 0.42 B158DRAFT_0197 pyrroline-5-carboxylate reductase — —
Pseudomonas sp. S08-1 0.55 OH686_10020 Shikimate kinase I 0.35 OH686_10980 pyrroline-5-carboxylate reductase 0.62 45
Pseudomonas segetis P6 0.54 ACVTMO_RS21000 aroK shikimate kinase AroK 0.36 ACVTMO_RS03015 proC pyrroline-5-carboxylate reductase — —
Pseudomonas stutzeri RCH2 0.54 Psest_3714 Shikimate kinase 0.34 Psest_0283 pyrroline-5-carboxylate reductase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.53 Psyr_0408 shikimate kinase 0.36 Psyr_0476 pyrroline-5-carboxylate reductase — —
Pseudomonas syringae pv. syringae B728a 0.53 Psyr_0408 shikimate kinase 0.36 Psyr_0476 pyrroline-5-carboxylate reductase — —
Pseudomonas aeruginosa PUPa3 0.52 NPBIFN_05354 aroK Shikimate kinase 0.35 NPBIFN_00406 proC pyrroline-5-carboxylate reductase — —
Acinetobacter baumannii LAC-4 0.52 RR41_RS01580 shikimate kinase AroK 0.38 RR41_RS15925 pyrroline-5-carboxylate reductase — —
Pseudomonas aeruginosa MRSN321 0.52 PFGADD_05278 aroK Shikimate kinase 0.35 PFGADD_00402 proC pyrroline-5-carboxylate reductase — —
Acinetobacter radioresistens SK82 0.52 MPMX26_02811 Shikimate kinase 1 0.38 MPMX26_00572 Pyrroline-5-carboxylate reductase — —
Pseudomonas aeruginosa PA14 0.52 IKLFDK_28335 Shikimate kinase 0.35 IKLFDK_23455 pyrroline-5-carboxylate reductase — —
Pseudomonas sp. SVBP6 0.52 COO64_RS13070 aroK shikimate kinase AroK 0.36 COO64_RS12995 proC pyrroline-5-carboxylate reductase — —
Pseudomonas fluorescens FW300-N2C3 0.52 AO356_09390 shikimate kinase 0.36 AO356_13420 pyrroline-5-carboxylate reductase — —
Pseudomonas simiae WCS417 0.51 PS417_01980 shikimate kinase 0.36 PS417_26730 pyrroline-5-carboxylate reductase — —
Pseudomonas fluorescens SBW25-INTG 0.51 PFLU_RS02025 shikimate kinase AroK 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase — —
Marinobacter adhaerens HP15 0.51 HP15_479 shikimate kinase I 0.38 HP15_287 pyrroline-5-carboxylate reductase — —
Pseudomonas fluorescens FW300-N2E3 0.51 AO353_12500 shikimate kinase 0.36 AO353_08165 pyrroline-5-carboxylate reductase 0.66 8
Pseudomonas orientalis W4I3 0.51 QF045_RS05045 shikimate kinase AroK 0.37 QF045_RS01130 pyrroline-5-carboxylate reductase — —
Pseudomonas fluorescens SBW25 0.51 PFLU_RS02025 shikimate kinase AroK 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase — —
Pseudomonas sp. BP01 0.51 JOY50_RS09300 aroK shikimate kinase AroK 0.37 JOY50_RS20905 proC pyrroline-5-carboxylate reductase — —
Pseudomonas putida KT2440 0.50 PP_5079 Shikimate kinase 0.37 PP_5095 pyrroline-5-carboxylate reductase — —
Pseudomonas fluorescens GW456-L13 0.48 PfGW456L13_276 Shikimate kinase I (EC 2.7.1.71) 0.35 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.80 15
Pseudomonas protegens RBAN4 0.48 FABNJH_02350 aroK shikimate kinase AroK 0.36 FABNJH_29430 proC pyrroline-5-carboxylate reductase — —
Pseudomonas sp. RS175 0.48 PFR28_05012 Shikimate kinase 1 0.35 PFR28_04243 Pyrroline-5-carboxylate reductase — —
Pseudomonas fluorescens FW300-N2E2 0.48 Pf6N2E2_3755 Shikimate kinase I (EC 2.7.1.71) 0.35 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) — —
Pseudomonas fluorescens FW300-N1B4 0.47 Pf1N1B4_1538 Shikimate kinase I (EC 2.7.1.71) 0.35 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) — —
Pseudomonas lactucae CFBP13502 0.47 GEMAOFIL_00629 Shikimate kinase 1 0.37 GEMAOFIL_05483 Pyrroline-5-carboxylate reductase — —
Pseudomonas sp. DMC3 0.47 GFF3099 Shikimate kinase 1 0.34 GFF210 Pyrroline-5-carboxylate reductase — —
Paraburkholderia sabiae LMG 24235 0.47 QEN71_RS28040 shikimate kinase 0.36 QEN71_RS26600 pyrroline-5-carboxylate reductase 0.92 15
Castellaniella sp019104865 MT123 0.47 ABCV34_RS12700 shikimate kinase 0.32 ABCV34_RS03610 pyrroline-5-carboxylate reductase — —
Paraburkholderia graminis OAS925 0.46 ABIE53_003741 shikimate kinase 0.37 ABIE53_000840 pyrroline-5-carboxylate reductase — —
Paraburkholderia bryophila 376MFSha3.1 0.46 H281DRAFT_05614 shikimate kinase 0.35 H281DRAFT_04679 pyrroline-5-carboxylate reductase — —
Burkholderia phytofirmans PsJN 0.46 BPHYT_RS17890 shikimate kinase 0.35 BPHYT_RS03490 pyrroline-5-carboxylate reductase — —
Cupriavidus basilensis FW507-4G11 0.46 RR42_RS19010 shikimate kinase 0.30 RR42_RS17360 pyrroline-5-carboxylate reductase — —
Rhodanobacter sp000427505 FW510-R12 0.45 LRK53_RS05625 shikimate kinase 0.30 LRK53_RS05680 pyrroline-5-carboxylate reductase low > 59
Rhodanobacter denitrificans MT42 0.45 LRK55_RS04080 shikimate kinase 0.29 LRK55_RS04030 pyrroline-5-carboxylate reductase low > 63
Rhodanobacter denitrificans FW104-10B01 0.45 LRK54_RS04305 shikimate kinase 0.29 LRK54_RS04260 pyrroline-5-carboxylate reductase low > 59
Dechlorosoma suillum PS 0.45 Dsui_1094 shikimate kinase 0.36 Dsui_0602 pyrroline-5-carboxylate reductase — —
Methylophilus sp. DMC18 0.44 GFF2235 Shikimate kinase 1 0.31 GFF863 Pyrroline-5-carboxylate reductase — —
Rhodanobacter sp. FW510-T8 0.44 OKGIIK_11180 Shikimate kinase 0.30 OKGIIK_11135 proC pyrroline-5-carboxylate reductase 0.76 39
Ralstonia sp. UNC404CL21Col 0.43 ABZR87_RS02595 shikimate kinase 0.35 ABZR87_RS01230 pyrroline-5-carboxylate reductase — —
Dyella japonica UNC79MFTsu3.2 0.42 ABZR86_RS10475 shikimate kinase 0.32 ABZR86_RS10425 pyrroline-5-carboxylate reductase 0.86 74
Ralstonia solanacearum PSI07 0.42 RPSI07_RS10295 shikimate kinase 0.32 RPSI07_RS11720 pyrroline-5-carboxylate reductase low > 81
Ralstonia solanacearum IBSBF1503 0.41 RALBFv3_RS06940 shikimate kinase 0.32 RALBFv3_RS05580 pyrroline-5-carboxylate reductase 0.78 4
Ralstonia solanacearum UW163 0.41 UW163_RS06675 shikimate kinase 0.32 UW163_RS08045 pyrroline-5-carboxylate reductase — —
Ralstonia solanacearum GMI1000 0.41 RS_RS14885 shikimate kinase 0.33 RS_RS13440 pyrroline-5-carboxylate reductase — —
Xanthomonas campestris pv. campestris strain 8004 0.40 Xcc-8004.1616.1 Shikimate kinase I (EC 2.7.1.71) 0.30 Xcc-8004.1710.1 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) low > 74
Hydrogenophaga sp. GW460-11-11-14-LB1 0.39 GFF1332 Shikimate kinase I (EC 2.7.1.71) 0.28 GFF2806 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) low > 90
Variovorax sp. OAS795 0.35 ABID97_RS23260 shikimate kinase 0.32 ABID97_RS01555 pyrroline-5-carboxylate reductase — —
Magnetospirillum magneticum AMB-1 0.34 AMB_RS19870 shikimate kinase 0.28 AMB_RS02820 pyrroline-5-carboxylate reductase — —
Acidovorax sp. GW101-3H11 0.32 Ac3H11_3449 Shikimate kinase I (EC 2.7.1.71) 0.32 Ac3H11_788 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) — —
Variovorax sp. SCN45 0.30 GFF5324 Shikimate kinase I (EC 2.7.1.71) 0.31 GFF5553 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) — —

Not shown: 20 genomes with orthologs for CSW01_13305 only; 7 genomes with orthologs for CSW01_02450 only