Conservation of cofitness between Atu0043 and Atu2264 in Agrobacterium fabrum C58

52 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu0043 imidazoleglycerol-phosphate dehydratase 1.0 Atu2264 2-isopropylmalate synthase 0.83 17
Rhizobium sp. OAE497 0.91 ABIE40_RS19460 imidazoleglycerol-phosphate dehydratase HisB 0.87 ABIE40_RS13330 2-isopropylmalate synthase 0.95 18
Sinorhizobium meliloti 1021 0.88 SMc02574 imidazoleglycerol-phosphate dehydratase 0.88 SMc02717 2-isopropylmalate synthase 0.74 24
Bosea sp. OAE506 0.69 ABIE41_RS03965 imidazoleglycerol-phosphate dehydratase HisB 0.11 ABIE41_RS13000 2-isopropylmalate synthase low > 77
Dinoroseobacter shibae DFL-12 0.66 Dshi_0794 Imidazoleglycerol-phosphate dehydratase (RefSeq) 0.12 Dshi_0596 2-isopropylmalate synthase (RefSeq) — —
Phaeobacter inhibens DSM 17395 0.65 PGA1_c09330 imidazoleglycerol-phosphate dehydratase HisB 0.11 PGA1_c26470 2-isopropylmalate synthase LeuA — —
Rhodospirillum rubrum S1H 0.65 Rru_A3597 Imidazoleglycerol-phosphate dehydratase (NCBI) 0.59 Rru_A1928 Yeast 2-isopropylmalate synthase (NCBI) — —
Sphingomonas koreensis DSMZ 15582 0.65 Ga0059261_1044 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.51 Ga0059261_4031 2-isopropylmalate synthase, yeast type 0.98 16
Azospirillum sp. SherDot2 0.63 MPMX19_02546 Histidine biosynthesis bifunctional protein HisB 0.59 MPMX19_01822 2-isopropylmalate synthase — —
Azospirillum brasilense Sp245 0.63 AZOBR_RS01665 imidazoleglycerol-phosphate dehydratase 0.58 AZOBR_RS12155 2-isopropylmalate synthase 0.88 14
Magnetospirillum magneticum AMB-1 0.62 AMB_RS22940 imidazoleglycerol-phosphate dehydratase 0.55 AMB_RS17550 2-isopropylmalate synthase — —
Rhodopseudomonas palustris CGA009 0.59 TX73_001605 imidazoleglycerol-phosphate dehydratase HisB 0.50 TX73_024250 2-isopropylmalate synthase — —
Acidovorax sp. GW101-3H11 0.59 Ac3H11_4730 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.46 Ac3H11_5000 2-isopropylmalate synthase (EC 2.3.3.13) — —
Caulobacter crescentus NA1000 0.59 CCNA_03850 imidazoleglycerol-phosphate dehydratase 0.10 CCNA_01610 2-isopropylmalate synthase low > 66
Variovorax sp. OAS795 0.59 ABID97_RS23140 imidazoleglycerol-phosphate dehydratase HisB 0.50 ABID97_RS14905 2-isopropylmalate synthase — —
Variovorax sp. SCN45 0.59 GFF5349 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.50 GFF1164 2-isopropylmalate synthase (EC 2.3.3.13) — —
Caulobacter crescentus NA1000 Δfur 0.59 CCNA_03850 imidazoleglycerol-phosphate dehydratase 0.10 CCNA_01610 2-isopropylmalate synthase 0.69 23
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS17700 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) (from data) 0.50 BPHYT_RS13280 2-isopropylmalate synthase low > 109
Paraburkholderia graminis OAS925 0.58 ABIE53_003699 imidazoleglycerol-phosphate dehydratase 0.50 ABIE53_002867 2-isopropylmalate synthase — —
Paraburkholderia bryophila 376MFSha3.1 0.58 H281DRAFT_05655 imidazoleglycerol-phosphate dehydratase 0.51 H281DRAFT_00385 2-isopropylmalate synthase — —
Dechlorosoma suillum PS 0.57 Dsui_1415 imidazoleglycerol-phosphate dehydratase 0.51 Dsui_3227 2-isopropylmalate synthase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.57 GFF1312 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.50 GFF4280 2-isopropylmalate synthase (EC 2.3.3.13) — —
Pseudomonas sp. S08-1 0.56 OH686_14575 Imidazoleglycerol-phosphate dehydratase 0.52 OH686_17570 2-isopropylmalate synthase 0.64 28
Ralstonia solanacearum GMI1000 0.56 RS_RS14780 imidazoleglycerol-phosphate dehydratase 0.51 RS_RS18695 2-isopropylmalate synthase 2 — —
Ralstonia sp. UNC404CL21Col 0.56 ABZR87_RS02490 imidazoleglycerol-phosphate dehydratase HisB 0.52 ABZR87_RS22365 2-isopropylmalate synthase — —
Ralstonia solanacearum PSI07 0.56 RPSI07_RS10400 imidazoleglycerol-phosphate dehydratase HisB 0.52 RPSI07_RS01320 2-isopropylmalate synthase — —
Herbaspirillum seropedicae SmR1 0.56 HSERO_RS20330 imidazoleglycerol-phosphate dehydratase 0.52 HSERO_RS17185 2-isopropylmalate synthase 0.88 12
Pseudomonas stutzeri RCH2 0.56 Psest_0152 Imidazoleglycerol-phosphate dehydratase 0.55 Psest_1277 2-isopropylmalate synthase, yeast type 0.66 35
Ralstonia solanacearum UW163 0.56 UW163_RS06780 imidazoleglycerol-phosphate dehydratase 0.53 UW163_RS17345 2-isopropylmalate synthase — —
Ralstonia solanacearum IBSBF1503 0.56 RALBFv3_RS06835 imidazoleglycerol-phosphate dehydratase 0.53 RALBFv3_RS21840 2-isopropylmalate synthase — —
Synechococcus elongatus PCC 7942 0.55 Synpcc7942_0125 hisB imidazoleglycerol-phosphate dehydratase 0.09 Synpcc7942_1410 leuA 2-isopropylmalate synthase — —
Pseudomonas fluorescens FW300-N2E3 0.55 AO353_12070 imidazoleglycerol-phosphate dehydratase 0.53 AO353_15925 2-isopropylmalate synthase 0.88 18
Cupriavidus basilensis FW507-4G11 0.55 RR42_RS18905 imidazoleglycerol-phosphate dehydratase 0.49 RR42_RS21205 2-isopropylmalate synthase — —
Acinetobacter radioresistens SK82 0.54 MPMX26_02845 Histidine biosynthesis bifunctional protein HisB 0.50 MPMX26_00404 2-isopropylmalate synthase 0.85 31
Pseudomonas simiae WCS417 0.54 PS417_01560 imidazoleglycerol-phosphate dehydratase 0.53 PS417_23110 2-isopropylmalate synthase 0.62 28
Pseudomonas syringae pv. syringae B728a ΔmexB 0.54 Psyr_4897 imidazoleglycerol-phosphate dehydratase 0.53 Psyr_1257 2-isopropylmalate synthase 0.75 12
Pseudomonas syringae pv. syringae B728a 0.54 Psyr_4897 imidazoleglycerol-phosphate dehydratase 0.53 Psyr_1257 2-isopropylmalate synthase 0.85 13
Pseudomonas sp. RS175 0.54 PFR28_04929 Histidine biosynthesis bifunctional protein HisB 0.53 PFR28_00305 2-isopropylmalate synthase 0.66 10
Pseudomonas fluorescens FW300-N2C3 0.54 AO356_09815 imidazoleglycerol-phosphate dehydratase 0.53 AO356_06550 2-isopropylmalate synthase 0.88 25
Pseudomonas fluorescens GW456-L13 0.54 PfGW456L13_362 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.52 PfGW456L13_4854 2-isopropylmalate synthase (EC 2.3.3.13) 0.89 20
Pseudomonas fluorescens FW300-N2E2 0.54 Pf6N2E2_3842 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.53 Pf6N2E2_3170 2-isopropylmalate synthase (EC 2.3.3.13) 0.82 21
Pseudomonas fluorescens SBW25 0.54 PFLU_RS01605 imidazoleglycerol-phosphate dehydratase HisB 0.53 PFLU_RS24765 2-isopropylmalate synthase 0.65 16
Pseudomonas fluorescens SBW25-INTG 0.54 PFLU_RS01605 imidazoleglycerol-phosphate dehydratase HisB 0.53 PFLU_RS24765 2-isopropylmalate synthase 0.79 16
Pseudomonas fluorescens FW300-N1B4 0.53 Pf1N1B4_1627 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.53 Pf1N1B4_847 2-isopropylmalate synthase (EC 2.3.3.13) 0.83 14
Marinobacter adhaerens HP15 0.53 HP15_3012 imidazoleglycerol-phosphate dehydratase 0.48 HP15_2055 2-isopropylmalate synthase — —
Pseudomonas putida KT2440 0.52 PP_0289 Imidazoleglycerol-phosphate dehydratase 0.54 PP_1025 2-isopropylmalate synthase 0.84 27
Castellaniella sp019104865 MT123 0.52 ABCV34_RS11235 imidazoleglycerol-phosphate dehydratase HisB 0.48 ABCV34_RS12420 2-isopropylmalate synthase 0.61 44
Bifidobacterium breve UCC2003 0.44 BBR_RS17045 imidazoleglycerol-phosphate dehydratase 0.50 BBR_RS11170 2-isopropylmalate synthase low > 34
Mycobacterium tuberculosis H37Rv 0.42 Rv1601 Probable imidazole glycerol-phosphate dehydratase HisB 0.52 Rv3710 2-isopropylmalate synthase LeuA (alpha-isopropylmalate synthase) (alpha-IPM synthetase) (IPMS) — —
Methanococcus maripaludis JJ 0.39 MMJJ_RS02175 imidazoleglycerol-phosphate dehydratase HisB 0.10 MMJJ_RS08870 2-isopropylmalate synthase — —
Methanococcus maripaludis S2 0.39 MMP_RS02900 imidazoleglycerol-phosphate dehydratase HisB 0.10 MMP_RS05500 2-isopropylmalate synthase low > 25
Desulfovibrio vulgaris Hildenborough JW710 0.38 DVU1040 hisB imidazoleglycerol-phosphate dehydratase (TIGR) 0.12 DVU2981 leuA 2-isopropylmalate synthase (TIGR) 0.82 21
Desulfovibrio vulgaris Miyazaki F 0.35 DvMF_3122 Imidazoleglycerol-phosphate dehydratase (RefSeq) 0.13 DvMF_1791 2-isopropylmalate synthase (RefSeq) 0.86 21

Not shown: 2 genomes with orthologs for Atu0043 only; 42 genomes with orthologs for Atu2264 only