| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Azospirillum sp. SherDot2 | MPMX19_06703 | | HTH-type transcriptional regulator HmrR | insig. | 100 | 100 |
| | Azospirillum sp. SherDot2 | MPMX19_06374 | | HTH-type transcriptional regulator HmrR | insig. | 77 | 92 |
| | Rhodospirillum rubrum S1H | Rru_A1026 | | Transcriptional Regulator, MerR family (NCBI) | insig. | 68 | 92 |
| | Rhizobium sp. OAE497 | ABIE40_RS15545 | | helix-turn-helix domain-containing protein | insig. | 58 | 91 |
| | Dinoroseobacter shibae DFL-12 | Dshi_3623 | | transcriptional regulator, MerR family (RefSeq) | no data | 56 | 89 |
| o | Dinoroseobacter shibae DFL-12 | Dshi_3961 | | transcriptional regulator, MerR family (RefSeq) | no data | 56 | 89 |
| o | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS11775 | | helix-turn-helix domain-containing protein | cofit | 54 | 91 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS03105 | | helix-turn-helix domain-containing protein | insig. | 57 | 88 |
| o | Xanthobacter sp. DMC5 | GFF2151 | | hypothetical protein | no data | 54 | 91 |
| o | Phaeobacter inhibens DSM 17395 | PGA1_262p00460 | | transcriptional regulator, MerR family | strong | 54 | 91 |
| | Sphingobium sp. HT1-2 | GFF5186 | | Heavy metal resistance transcriptional regulator HmrR | cofit | 52 | 85 |
| | Agrobacterium fabrum C58 | Atu0888 | | transcriptional regulator, MerR family | strong | 48 | 87 |
| | Sinorhizobium meliloti 1021 | SMc00109 | | transcriptional regulator | insig. | 49 | 87 |
| o | Bosea sp. OAE506 | ABIE41_RS05340 | | helix-turn-helix domain-containing protein | insig. | 49 | 91 |
| o | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3027 | | Predicted transcriptional regulators | insig. | 47 | 84 |
| | Pseudomonas segetis P6 | MPMX49_02844 | | Mercuric resistance operon regulatory protein | insig. | 45 | 91 |
| o | Magnetospirillum magneticum AMB-1 | AMB_RS05180 | | MerR family DNA-binding transcriptional regulator | insig. | 48 | 85 |
| o | Azospirillum brasilense Sp245 | AZOBR_RS27570 | | MerR family transcriptional regulator | insig. | 47 | 85 |
| | Rhodopseudomonas palustris CGA009 | TX73_016860 | | helix-turn-helix domain-containing protein | insig. | 46 | 84 |
| | Pseudomonas stutzeri RCH2 | Psest_2758 | | Predicted transcriptional regulators | insig. | 46 | 85 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS08670 | | heavy metal-responsive transcriptional regulator | insig. | 44 | 89 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS08955 | | Cu(I)-responsive transcriptional regulator | insig. | 39 | 94 |
| | Ralstonia solanacearum UW163 | UW163_RS04655 | | Cu(I)-responsive transcriptional regulator | insig. | 39 | 94 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS08315 | | Cu(I)-responsive transcriptional regulator | insig. | 39 | 94 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS01745 | | heavy metal-responsive transcriptional regulator | insig. | 45 | 85 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_05540 | | heavy metal-responsive transcriptional regulator | insig. | 44 | 89 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS08015 | | MerR family transcriptional regulator | insig. | 39 | 91 |
| o | Rhodanobacter denitrificans MT42 | LRK55_RS17035 | | helix-turn-helix domain-containing protein | insig. | 44 | 83 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_06310 | | MerR family transcriptional regulator | insig. | 44 | 83 |
| | Azospirillum sp. SherDot2 | MPMX19_04396 | | HTH-type transcriptional regulator HmrR | insig. | 42 | 84 |
| | Azospirillum brasilense Sp245 | AZOBR_RS19845 | | MerR family transcriptional regulator | insig. | 40 | 89 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS04230 | | Cu(I)-responsive transcriptional regulator | insig. | 38 | 89 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1242 | | transcriptional regulator, MerR family | insig. | 43 | 90 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS01130 | | MerR family transcriptional regulator | insig. | 45 | 88 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS01365 | | heavy metal-responsive transcriptional regulator | strong | 45 | 88 |
| | Azospirillum sp. SherDot2 | MPMX19_06429 | | HTH-type transcriptional regulator HmrR | insig. | 41 | 81 |
| | Paraburkholderia graminis OAS925 | ABIE53_001636 | | MerR family copper efflux transcriptional regulator | insig. | 41 | 94 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS06865 | | MerR family transcriptional regulator | insig. | 43 | 85 |
| | Shewanella amazonensis SB2B | Sama_1785 | | MerR family transcriptional regulator (RefSeq) | insig. | 39 | 84 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS16990 | | Cd(II)/Pb(II)-responsive transcriptional regulator | insig. | 42 | 85 |
| | Ralstonia solanacearum GMI1000 | RS_RS16770 | | Cu(I)-responsive transcriptional regulator | insig. | 38 | 90 |
| | Methylophilus sp. DMC18 | GFF1813 | | HTH-type transcriptional regulator HmrR | insig. | 37 | 85 |
| | Dechlorosoma suillum PS | Dsui_1064 | | Cu(I)-responsive transcriptional regulator | cofit | 37 | 88 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS23915 | | Cu(I)-responsive transcriptional regulator | insig. | 43 | 84 |
| | Marinobacter adhaerens HP15 | HP15_89 | | transcriptional regulator, MerR family protein | insig. | 41 | 85 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_04982 | | transcriptional regulator, MerR family | insig. | 44 | 85 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS20300 | | MerR family transcriptional regulator | insig. | 40 | 83 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02296 | | transcriptional regulator, MerR family | cofit | 41 | 85 |
| | Bosea sp. OAE506 | ABIE41_RS15580 | | Cu(I)-responsive transcriptional regulator | insig. | 40 | 84 |
| o | Shewanella sp. ANA-3 | Shewana3_4323 | | MerR family transcriptional regulator (RefSeq) | insig. | 39 | 83 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_18835 | | Cd(II)/Pb(II)-responsive transcriptional regulator | insig. | 47 | 74 |
| | Sinorhizobium meliloti 1021 | SM_b21579 | | MerR family transcriptional regulator | insig. | 39 | 85 |
| | Pseudomonas sp. S08-1 | OH686_16085 | | Transcriptional regulator, MerR family | insig. | 45 | 89 |
| | Pseudomonas segetis P6 | MPMX49_01108 | | HTH-type transcriptional regulator HmrR | insig. | 38 | 83 |
| | Pseudomonas simiae WCS417 | PS417_03155 | | transcriptional regulator | insig. | 38 | 87 |
| | Pseudomonas sp. DMC3 | GFF3355 | | HTH-type transcriptional regulator HmrR | cofit | 39 | 84 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_0653 | | transcriptional regulator, MerR family | sig. | 38 | 87 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_0653 | | transcriptional regulator, MerR family | insig. | 38 | 87 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_00846 | | HTH-type transcriptional regulator HmrR | cofit | 37 | 87 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS09150 | | Cu(I)-responsive transcriptional regulator | cofit | 39 | 84 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_08070 | | transcriptional regulator | strong | 39 | 84 |
| | Sphingobium sp. HT1-2 | GFF3389 | | Heavy metal resistance transcriptional regulator HmrR | cofit | 40 | 83 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_3488 | | Cu(I)-responsive transcriptional regulator | strong | 39 | 84 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS03235 | | Cu(I)-responsive transcriptional regulator | insig. | 37 | 87 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS03235 | | Cu(I)-responsive transcriptional regulator | strong | 37 | 87 |
| | Variovorax sp. SCN45 | GFF3315 | | Cu(I)-responsive transcriptional regulator | insig. | 36 | 85 |
| | Shewanella sp. ANA-3 | Shewana3_4158 | | MerR family transcriptional regulator (RefSeq) | cofit | 34 | 87 |
| | Acinetobacter baumannii LAC-4 | RR41_RS10230 | | Cu(I)-responsive transcriptional regulator | insig. | 34 | 82 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4249 | | Cu(I)-responsive transcriptional regulator | insig. | 36 | 84 |
| | Rahnella sp. WP5 | EX31_RS16005 | | Zn(2+)-responsive transcriptional regulator | insig. | 37 | 85 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_1263 | | Cu(I)-responsive transcriptional regulator | sig. | 38 | 84 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0423 | | Cu(I)-responsive transcriptional regulator | insig. | 38 | 85 |
| | Pseudomonas sp. RS175 | PFR28_05243 | | HTH-type transcriptional regulator HmrR | insig. | 38 | 84 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_06160 | | transcriptional regulator | strong | 38 | 84 |
| | Serratia liquefaciens MT49 | IAI46_13405 | | Cu(I)-responsive transcriptional regulator | insig. | 36 | 86 |
| | Dickeya dadantii 3937 | DDA3937_RS02550 | | Cd(II)/Pb(II)-responsive transcriptional regulator | sig. | 39 | 84 |
| | Acinetobacter radioresistens SK82 | MPMX26_02989 | | HTH-type transcriptional regulator CueR | insig. | 35 | 83 |
| | Paraburkholderia graminis OAS925 | ABIE53_000366 | | Cd(II)/Pb(II)-responsive transcriptional regulator | insig. | 39 | 85 |
| | Pseudomonas stutzeri RCH2 | Psest_0737 | | Cu(I)-responsive transcriptional regulator | sig. | 38 | 82 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_25 | | Cu(I)-responsive transcriptional regulator | insig. | 37 | 83 |
| | Dickeya dianthicola 67-19 | HGI48_RS02580 | | Cd(II)/Pb(II)-responsive transcriptional regulator | insig. | 39 | 84 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1161 | | Cu(I)-responsive transcriptional regulator | insig. | 38 | 85 |
| o | Klebsiella michiganensis M5al | BWI76_RS25700 | | heavy metal-responsive transcriptional regulator | strong | 39 | 85 |
| | Acinetobacter baumannii LAC-4 | RR41_RS09250 | | MerR family transcriptional regulator | insig. | 35 | 85 |
| | Acinetobacter radioresistens SK82 | MPMX26_01947 | | HTH-type transcriptional regulator HmrR | no data | 34 | 82 |
| | Agrobacterium fabrum C58 | Atu1197 | | transcriptional regulator, MerR family | insig. | 36 | 88 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3023 | | Predicted transcriptional regulators | insig. | 41 | 87 |
| | Dickeya dianthicola ME23 | DZA65_RS02685 | | Cd(II)/Pb(II)-responsive transcriptional regulator | insig. | 39 | 84 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS11645 | | helix-turn-helix domain-containing protein | insig. | 39 | 80 |
| | Pseudomonas sp. BP01 | JOY50_RS23260 | cueR | Cu(I)-responsive transcriptional regulator | insig. | 36 | 89 |
| | Variovorax sp. SCN45 | GFF4030 | | Transcriptional regulator, MerR family | insig. | 40 | 77 |
| o | Klebsiella pneumoniae MKP103 | KDGMDA_06570 | | Zn(2+)-responsive transcriptional regulator | insig. | 39 | 85 |
| | Acinetobacter radioresistens SK82 | MPMX26_03101 | | Mercuric resistance operon regulatory protein | insig. | 38 | 84 |
| o | Escherichia coli BL21 | ECD_03143 | | zntA gene transcriptional activator | cofit | 38 | 85 |
| o | Escherichia coli ECOR27 | NOLOHH_09300 | zntR | Zn(2+)-responsive transcriptional regulator | insig. | 38 | 85 |
| o | Escherichia coli ECOR38 | HEPCGN_16330 | zntR | Zn(2+)-responsive transcriptional regulator | insig. | 38 | 85 |
| o | Escherichia coli ECRC100 | OKFHMN_17500 | zntR | Zn(2+)-responsive transcriptional regulator | insig. | 38 | 85 |
| o | Escherichia coli ECRC101 | MCAODC_08030 | zntR | Zn(2+)-responsive transcriptional regulator | insig. | 38 | 85 |
| o | Escherichia coli ECRC102 | NIAGMN_15270 | zntR | Zn(2+)-responsive transcriptional regulator | cofit | 38 | 85 |
| o | Escherichia coli ECRC62 | BNILDI_02220 | zntR | Zn(2+)-responsive transcriptional regulator | cofit | 38 | 85 |