Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| Klebsiella michiganensis M5al | BWI76_RS23590 | | EAL domain-containing protein | insig. | 100 | 100 |
| Klebsiella michiganensis M5al | BWI76_RS18680 | | EAL domain-containing protein | sig. | 74 | 92 |
o | Enterobacter sp. TBS_079 | MPMX20_02204 | | hypothetical protein | strong | 35 | 88 |
o | Enterobacter asburiae PDN3 | EX28DRAFT_1341 | | FOG: EAL domain | insig. | 32 | 97 |
| Rahnella sp. WP5 | EX31_RS09160 | | EAL domain-containing protein | insig. | 33 | 49 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_4037 | | diguanylate cyclase (GGDEF) domain | insig. | 29 | 48 |
| Pseudomonas sp. S08-1 | OH686_00995 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 29 | 49 |
| Paraburkholderia graminis OAS925 | ABIE53_003996 | | diguanylate cyclase (GGDEF)-like protein | sig. | 30 | 52 |
| Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_01352 | | diguanylate cyclase/phosphodiesterase | insig. | 30 | 51 |
| Pseudomonas sp. RS175 | PFR28_01206 | | hypothetical protein | insig. | 28 | 51 |
| Rhodopseudomonas palustris CGA009 | TX73_002700 | | bifunctional diguanylate cyclase/phosphodiesterase | insig. | 30 | 54 |
| Pantoea sp. MT58 | IAI47_03300 | | EAL domain-containing protein | insig. | 31 | 49 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2284.1 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 31 | 51 |
| Desulfovibrio vulgaris Miyazaki F | DvMF_1907 | | diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) (RefSeq) | insig. | 30 | 53 |
| Acidovorax sp. GW101-3H11 | Ac3H11_1143 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | sig. | 28 | 50 |
| Azospirillum sp. SherDot2 | MPMX19_05708 | | hypothetical protein | insig. | 28 | 56 |
| Shewanella sp. ANA-3 | Shewana3_2201 | | response regulator receiver modulated diguanylate phosphodiesterase (RefSeq) | insig. | 31 | 49 |
| Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2238 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 28 | 52 |
| Sinorhizobium meliloti 1021 | SMa0137 | | Diguanylate cyclase/phosphodiesterase | insig. | 31 | 49 |
| Agrobacterium fabrum C58 | Atu3495 | | diguanylate cyclase | sig. | 30 | 49 |
| Pseudomonas stutzeri RCH2 | Psest_3901 | | diguanylate cyclase (GGDEF) domain | cofit | 29 | 46 |
| Dyella japonica UNC79MFTsu3.2 | ABZR86_RS14405 | | EAL domain-containing protein | insig. | 29 | 51 |
| Acidovorax sp. GW101-3H11 | Ac3H11_2210 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 28 | 50 |
| Burkholderia phytofirmans PsJN | BPHYT_RS23230 | | histidine kinase | insig. | 28 | 51 |
| Vibrio cholerae E7946 ATCC 55056 | CSW01_03465 | | GGDEF-domain containing protein | cofit | 25 | 59 |
| Burkholderia phytofirmans PsJN | BPHYT_RS27880 | | diguanylate phosphodiesterase | insig. | 30 | 51 |
| Enterobacter asburiae PDN3 | EX28DRAFT_1441 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain | insig. | 26 | 58 |
| Ralstonia solanacearum IBSBF1503 | RALBFv3_RS18745 | | histidine kinase | insig. | 30 | 50 |
| Ralstonia solanacearum UW163 | UW163_RS20385 | | histidine kinase | insig. | 30 | 50 |
| Rhodopseudomonas palustris CGA009 | TX73_017630 | | EAL domain-containing protein | insig. | 29 | 45 |
| Pantoea sp. MT58 | IAI47_11105 | | bifunctional diguanylate cyclase/phosphodiesterase | insig. | 26 | 49 |
| Sinorhizobium meliloti 1021 | SMc00992 | | hypothetical protein | insig. | 27 | 47 |
| Synechococcus elongatus PCC 7942 | Synpcc7942_1859 | | diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) | insig. | 28 | 49 |
| Rhizobium sp. OAE497 | ABIE40_RS27590 | | EAL domain-containing protein | insig. | 27 | 50 |
| Shewanella oneidensis MR-1 | SO2539 | | response regulator (NCBI ptt file) | insig. | 27 | 50 |
| Enterobacter sp. TBS_079 | MPMX20_02056 | | hypothetical protein | insig. | 28 | 54 |
| Ralstonia solanacearum PSI07 | RPSI07_RS04850 | | PAS domain S-box protein | insig. | 30 | 50 |
| Marinobacter adhaerens HP15 | HP15_845 | | sensory box/GGDEF family protein | insig. | 27 | 49 |
| Azospirillum sp. SherDot2 | MPMX19_00900 | | hypothetical protein | insig. | 26 | 53 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_0097 | | diguanylate cyclase (GGDEF) domain | insig. | 31 | 44 |
| Pectobacterium carotovorum WPP14 | HER17_RS11575 | | EAL domain-containing protein | cofit | 28 | 52 |
| Pseudomonas syringae pv. syringae B728a | Psyr_2711 | | diguanylate cyclase/phosphodiesterase | insig. | 29 | 46 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_2711 | | diguanylate cyclase/phosphodiesterase | insig. | 29 | 46 |
| Dechlorosoma suillum PS | Dsui_0983 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein | insig. | 28 | 48 |
| Escherichia coli ECOR38 | HEPCGN_24630 | pdeG | putative cyclic di-GMP phosphodiesterase PdeG | cofit | 26 | 51 |
| Sinorhizobium meliloti 1021 | SMa1548 | | Diguanylate cyclase/phosphodiesterase | insig. | 28 | 47 |
| Agrobacterium fabrum C58 | Atu3244 | | diguanylate cyclase | insig. | 26 | 49 |
| Rhizobium sp. OAE497 | ABIE40_RS15540 | | EAL domain-containing protein | insig. | 28 | 50 |
| Escherichia coli ECRC99 | KEDOAH_25170 | pdeG | putative cyclic di-GMP phosphodiesterase PdeG | no data | 26 | 51 |
| Caulobacter crescentus NA1000 | CCNA_03191 | | PAS-family GGDEF/EAL family protein | cofit | 27 | 52 |
| Caulobacter crescentus NA1000 Δfur | CCNA_03191 | | PAS-family GGDEF/EAL family protein | cofit | 27 | 52 |
| Escherichia coli BL21 | ECD_01143 | | putative membrane-anchored cyclic-di-GMP phosphodiesterase | no data | 26 | 51 |
| Escherichia coli ECOR27 | NOLOHH_20845 | pdeG | putative cyclic di-GMP phosphodiesterase PdeG | no data | 26 | 51 |
| Escherichia coli ECRC62 | BNILDI_19005 | pdeG | putative cyclic di-GMP phosphodiesterase PdeG | insig. | 26 | 51 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02523 | | putative cyclic di-GMP phosphodiesterase PdeG | insig. | 26 | 51 |
| Azospirillum sp. SherDot2 | MPMX19_02219 | | hypothetical protein | insig. | 30 | 48 |
| Marinobacter adhaerens HP15 | HP15_3728 | | sensory box/GGDEF/GAF/EAL domain protein | insig. | 28 | 48 |
| Rhizobium sp. OAE497 | ABIE40_RS16745 | | EAL domain-containing protein | insig. | 26 | 52 |
| Azospirillum sp. SherDot2 | MPMX19_06128 | | hypothetical protein | insig. | 25 | 52 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS28225 | | diguanylate cyclase | insig. | 29 | 43 |
| Desulfovibrio vulgaris Hildenborough JW710 | DVU0022 | | HAMP domain/GGDEF domain/EAL domain protein (TIGR) | insig. | 28 | 49 |
| Marinobacter adhaerens HP15 | HP15_1415 | | diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) | insig. | 27 | 49 |
| Vibrio cholerae E7946 ATCC 55056 | CSW01_09670 | | bifunctional diguanylate cyclase/phosphodiesterase | insig. | 27 | 51 |
| Escherichia coli BW25113 | b1168 | b1168 | putative proteases (VIMSS) | sig. | 26 | 51 |
| Phaeobacter inhibens DSM 17395 | PGA1_c16740 | | diguanylate cyclase domain-containing transport protein | insig. | 29 | 50 |
| Shewanella loihica PV-4 | Shew_0951 | | response regulator receiver modulated diguanylate phosphodiesterase (RefSeq) | insig. | 27 | 56 |
| Sinorhizobium meliloti 1021 | SM_b20447 | | hypothetical protein | insig. | 25 | 51 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS34815 | | diguanylate cyclase | strong | 26 | 49 |
| Klebsiella michiganensis M5al | BWI76_RS15995 | | bifunctional diguanylate cyclase/phosphodiesterase | insig. | 28 | 52 |
| Enterobacter asburiae PDN3 | EX28DRAFT_1790 | | FOG: EAL domain | insig. | 26 | 53 |
| Shewanella amazonensis SB2B | Sama_0388 | | putative diguanylate phosphodiesterase (RefSeq) | strong | 28 | 51 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_3704 | | diguanylate cyclase (GGDEF) domain | insig. | 27 | 49 |
| Pseudomonas sp. S08-1 | OH686_03800 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 27 | 49 |
| Paraburkholderia graminis OAS925 | ABIE53_001117 | | diguanylate cyclase (GGDEF)-like protein | insig. | 30 | 50 |
| Klebsiella michiganensis M5al | BWI76_RS18710 | | GGDEF-domain containing protein | strong | 28 | 58 |
| Kangiella aquimarina DSM 16071 | B158DRAFT_2502 | | periplasmic sensor diguanylate cyclase/phosphodiesterase | insig. | 26 | 49 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_1521 | | diguanylate cyclase (GGDEF) domain | cofit | 27 | 52 |
| Ralstonia sp. UNC404CL21Col | ABZR87_RS19215 | | EAL domain-containing protein | cofit | 28 | 49 |
| Azospirillum sp. SherDot2 | MPMX19_04558 | | hypothetical protein | insig. | 27 | 50 |
| Marinobacter adhaerens HP15 | HP15_3980 | | diguanylate cyclase/phosphodiesterase | insig. | 27 | 44 |
| Magnetospirillum magneticum AMB-1 | AMB_RS11515 | | DUF3365 domain-containing protein | insig. | 27 | 45 |
| Rhizobium sp. OAE497 | ABIE40_RS05245 | | EAL domain-containing protein | insig. | 27 | 62 |
| Shewanella loihica PV-4 | Shew_3724 | | diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) (RefSeq) | insig. | 26 | 51 |
| Burkholderia phytofirmans PsJN | BPHYT_RS05950 | | dGTP triphosphohydrolase | insig. | 25 | 62 |
| Desulfovibrio vulgaris Miyazaki F | DvMF_1530 | | diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) (RefSeq) | insig. | 25 | 54 |
| Klebsiella michiganensis M5al | BWI76_RS16255 | | histidine kinase | insig. | 30 | 50 |
| Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_39 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 27 | 50 |
| Pseudomonas sp. RS175 | PFR28_04179 | | Sensor histidine kinase RcsC | sig. | 25 | 74 |
| Rhizobium sp. OAE497 | ABIE40_RS28405 | | EAL domain-containing protein | insig. | 29 | 49 |
| Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS00470 | | bifunctional diguanylate cyclase/phosphodiesterase | insig. | 28 | 44 |
| Herbaspirillum seropedicae SmR1 | HSERO_RS03135 | | diguanylate cyclase | sig. | 27 | 54 |
| Rhodopseudomonas palustris CGA009 | TX73_002030 | | EAL domain-containing protein | insig. | 27 | 52 |
| Shewanella oneidensis MR-1 | SO4145 | | conserved hypothetical protein (NCBI ptt file) | insig. | 27 | 47 |
| Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_4666 | | Sensory box/GGDEF family protein | insig. | 25 | 74 |
| Azospirillum sp. SherDot2 | MPMX19_00480 | | hypothetical protein | insig. | 25 | 48 |
| Paraburkholderia graminis OAS925 | ABIE53_001451 | | diguanylate cyclase (GGDEF)-like protein/PAS domain S-box-containing protein | insig. | 29 | 50 |
| Pseudomonas simiae WCS417 | PS417_18610 | | histidine kinase | sig. | 28 | 46 |
| Magnetospirillum magneticum AMB-1 | AMB_RS23225 | | GGDEF domain-containing protein | insig. | 27 | 46 |
| Ralstonia solanacearum IBSBF1503 | RALBFv3_RS21640 | | GGDEF domain-containing protein | insig. | 25 | 49 |
| Ralstonia solanacearum UW163 | UW163_RS17545 | | GGDEF domain-containing protein | insig. | 25 | 49 |