| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Shewanella loihica PV-4 | Shew_1396 | | response regulator receiver protein (RefSeq) | insig. | 100 | 100 |
| o | Shewanella oneidensis MR-1 | SO3196 | | response regulator (NCBI ptt file) | strong | 65 | 100 |
| o | Shewanella sp. ANA-3 | Shewana3_1372 | | response regulator receiver protein (RefSeq) | strong | 64 | 100 |
| o | Shewanella amazonensis SB2B | Sama_2267 | | response regulator receiver protein (RefSeq) | strong | 66 | 100 |
| | Pseudomonas sp. DMC3 | GFF1302 | | Regulator of RpoS | no data | 33 | 73 |
| | Pseudomonas sp. BP01 | JOY50_RS25185 | rssB | two-component system response regulator RssB | no data | 33 | 73 |
| | Pseudomonas putida KT2440 | PP_2165 | | Response regulator | no data | 33 | 73 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS07795 | | SpoIIE family protein phosphatase | no data | 33 | 73 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS07795 | | SpoIIE family protein phosphatase | no data | 33 | 73 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4011 | | Serine phosphatase RsbU, regulator of sigma subunit | no data | 33 | 73 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_60 | | Serine phosphatase RsbU, regulator of sigma subunit | no data | 33 | 73 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_00320 | | chemotaxis protein CheY | no data | 33 | 73 |
| | Pseudomonas sp. SVBP6 | COO64_RS09545 | rssB | two-component system response regulator RssB | no data | 33 | 73 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01676 | | Regulator of RpoS | no data | 33 | 73 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_02185 | | chemotaxis protein CheY | no data | 33 | 73 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2260 | | Serine phosphatase RsbU, regulator of sigma subunit | no data | 33 | 73 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1912 | | Response regulator receiver:Stage II sporulation E | no data | 32 | 76 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1912 | | Response regulator receiver:Stage II sporulation E | no data | 32 | 76 |
| | Pseudomonas simiae WCS417 | PS417_07720 | | chemotaxis protein CheY | no data | 33 | 73 |
| | Pseudomonas sp. RS175 | PFR28_01140 | | Regulator of RpoS | no data | 33 | 73 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_14160 | | fused response regulator/phosphatase | no data | 31 | 73 |
| o | Pseudomonas stutzeri RCH2 | Psest_2710 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | no data | 28 | 88 |
| | Pseudomonas sp. S08-1 | OH686_22730 | | Serine phosphatase RsbU, regulator of sigma subunit | no data | 30 | 72 |
| o | Pseudomonas segetis P6 | MPMX49_01910 | | Regulator of RpoS | no data | 29 | 90 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_05345 | | two-component system response regulator | insig. | 30 | 64 |
| | Pectobacterium carotovorum WPP14 | HER17_RS11050 | | two-component system response regulator RssB | cofit | 28 | 62 |
| | Dickeya dianthicola 67-19 | HGI48_RS10350 | | two-component system response regulator RssB | cofit | 28 | 62 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1544 | | response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) (RefSeq) | insig. | 38 | 40 |
| | Dickeya dianthicola ME23 | DZA65_RS10825 | | two-component system response regulator RssB | sig. | 30 | 51 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_22690 | rssB | two-component system response regulator RssB | strong | 28 | 69 |
| | Erwinia tracheiphila SCR3 | LU632_RS12925 | rssB | two-component system response regulator RssB | cofit | 28 | 69 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_3074 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | cofit | 41 | 32 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_24505 | | two-component system response regulator RssB | sig. | 30 | 54 |
| | Rahnella sp. WP5 | EX31_RS10100 | | two-component system response regulator RssB | insig. | 27 | 69 |
| | Escherichia coli ECOR27 | NOLOHH_20465 | rssB | two-component system response regulator RssB | insig. | 30 | 52 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF2753 | | Hnr protein | strong | 31 | 52 |
| | Erwinia amylovora T8 | OLJFJH_13285 | | two-component system response regulator RssB | strong | 27 | 69 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS02865 | | two-component system response regulator RssB | no data | 27 | 54 |
| | Klebsiella michiganensis M5al | BWI76_RS17275 | | two-component system response regulator RssB | insig. | 28 | 54 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0408 | | response regulator/sensory box/GGDEF domain/EAL domain protein (TIGR) | sig. | 34 | 43 |
| | Pantoea sp. MT58 | IAI47_09025 | | two-component system response regulator RssB | no data | 27 | 54 |
| | Escherichia fergusonii Becca | EFB2_02691 | | Regulator of RpoS | sig. | 30 | 54 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS07475 | | two-component system response regulator RssB | no data | 30 | 54 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0482 | | sensory box histidine kinase/response regulator (TIGR) | insig. | 38 | 39 |
| | Escherichia coli BL21 | ECD_01211 | | PcnB-degradosome interaction factor; response regulator | strong | 30 | 52 |
| | Escherichia coli ECOR38 | HEPCGN_25045 | rssB | two-component system response regulator RssB | strong | 30 | 52 |
| | Escherichia coli ECRC100 | OKFHMN_28585 | rssB | two-component system response regulator RssB | cofit | 30 | 52 |
| | Escherichia coli ECRC101 | MCAODC_21675 | rssB | two-component system response regulator RssB | strong | 30 | 52 |
| | Escherichia coli ECRC102 | NIAGMN_27650 | rssB | two-component system response regulator RssB | no data | 30 | 52 |
| | Escherichia coli ECRC62 | BNILDI_18620 | rssB | two-component system response regulator RssB | strong | 30 | 52 |
| | Escherichia coli ECRC98 | JDDGAC_05990 | rssB | two-component system response regulator RssB | strong | 30 | 52 |
| | Escherichia coli ECRC99 | KEDOAH_25580 | rssB | two-component system response regulator RssB | no data | 30 | 52 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02450 | | Regulator of RpoS | strong | 30 | 52 |
| | Escherichia coli BW25113 | b1235 | rssB | response regulator of RpoS (NCBI) | strong | 30 | 52 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_0064 | | histidine kinase (RefSeq) | sig. | 37 | 32 |
| o | Serratia liquefaciens MT49 | IAI46_14250 | | two-component system response regulator RssB | insig. | 24 | 81 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1419 | | signal transduction histidine kinase (RefSeq) | cofit | 33 | 38 |
| | Enterobacter sp. TBS_079 | MPMX20_02593 | | Regulator of RpoS | strong | 33 | 47 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0888 | | response regulator (TIGR) | sig. | 29 | 43 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2550 | | multi-sensor signal transduction histidine kinase (RefSeq) | insig. | 38 | 31 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_0861 | | Response regulator receiver domain | strong | 31 | 47 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_1146 | | Serine phosphatase RsbU, regulator of sigma subunit | insig. | 25 | 90 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1181 | | response regulator (TIGR) | cofit | 36 | 32 |
| | Marinobacter adhaerens HP15 | HP15_806 | | response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) | insig. | 37 | 30 |
| | Dinoroseobacter shibae DFL-12 | Dshi_0823 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | cofit | 36 | 31 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1730 | | multi-sensor signal transduction histidine kinase (RefSeq) | insig. | 35 | 31 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU2967 | | sensor histidine kinase/response regulator (TIGR) | sig. | 35 | 31 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0258 | | sensory box histidine kinase/response regulator (TIGR) | strong | 34 | 29 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU3381 | ntrC | transcriptional regulatory protein zraR (TIGR) | strong | 33 | 29 |
| | Rhodospirillum rubrum S1H | Rru_A1282 | | Two component Transcriptional regulator, Winged helix family (NCBI) | insig. | 38 | 28 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_04380 | | response regulator | strong | 36 | 27 |
| | Dechlorosoma suillum PS | Dsui_0331 | | PAS domain S-box | insig. | 33 | 38 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_18195 | | chemotaxis protein CheY | insig. | 32 | 32 |
| | Pseudomonas sp. RS175 | PFR28_01496 | | Sensor histidine kinase RcsC | insig. | 31 | 32 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2107 | | response regulator receiver protein (RefSeq) | strong | 30 | 34 |
| | Cellulophaga baltica 18 | M666_RS19210 | | sigma-54 dependent transcriptional regulator | insig. | 37 | 27 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS08760 | | XRE family transcriptional regulator | no data | 36 | 32 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2149 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | strong | 35 | 28 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2109 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | strong | 39 | 27 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c07670 | | two component regulatory sytem | insig. | 36 | 31 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU3303 | lon | ATP-dependent protease La, truncation (TIGR) | cofit | 34 | 28 |
| | Dechlorosoma suillum PS | Dsui_3449 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein | cofit | 32 | 30 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0145 | | response regulator (TIGR) | sig. | 40 | 27 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1991 | | response regulator receiver protein (RefSeq) | no data | 35 | 31 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0732 | | two-component system response regulator (NCBI ptt file) | no data | 34 | 29 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS01790 | | LuxR family transcriptional regulator | strong | 36 | 32 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_1292 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | strong | 34 | 27 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS02280 | | hybrid sensor histidine kinase/response regulator | cofit | 34 | 33 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS21460 | | response regulator | insig. | 30 | 51 |
| | Marinobacter adhaerens HP15 | HP15_1764 | | two-component response regulator | strong | 25 | 52 |
| | Pseudomonas sp. SVBP6 | COO64_RS21290 | | sigma-54 dependent transcriptional regulator | insig. | 32 | 35 |
| | Rhodopseudomonas palustris CGA009 | TX73_008385 | | response regulator transcription factor | no data | 34 | 35 |
| | Azospirillum sp. SherDot2 | MPMX19_00002 | | Response regulator PleD | insig. | 32 | 31 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS03150 | | response regulator transcription factor | insig. | 31 | 41 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS03150 | | response regulator transcription factor | sig. | 31 | 41 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.5008.1 | | Two-component system regulatory protein | no data | 33 | 34 |
| | Cellulophaga baltica 18 | M666_RS17625 | | response regulator transcription factor | no data | 31 | 33 |
| | Paraburkholderia graminis OAS925 | ABIE53_000448 | | two-component system invasion response regulator UvrY | strong | 36 | 32 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS05625 | | response regulator | insig. | 33 | 34 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS00325 | | response regulator transcription factor | no data | 31 | 40 |