| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli BL21 | 1.0 | ECD_01634 | | multidrug efflux system transporter | 1.0 | ECD_04041 | | modulator for HflB protease specific for phage lambda cII repressor | 0.60 | 7 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 1.00 | OHPLBJKB_02061 | | Multidrug resistance protein MdtK | 1.00 | OHPLBJKB_03868 | | Modulator of FtsH protease HflK | low | > 73 |
| Escherichia fergusonii Becca | 1.00 | EFB2_02329 | | Multidrug resistance protein MdtK | 1.00 | EFB2_04361 | | Modulator of FtsH protease HflK | low | > 86 |
| Escherichia coli BW25113 | 1.00 | b1663 | mdtK | multidrug efflux protein NorM (NCBI) | 1.00 | b4174 | hflK | modulator for HflB protease specific for phage lambda cII repressor (NCBI) | low | > 76 |
| Escherichia coli ECOR38 | 1.00 | HEPCGN_05745 | mdtK | multidrug efflux MATE transporter MdtK | 1.00 | HEPCGN_10475 | hflK | FtsH protease activity modulator HflK | low | > 85 |
| Escherichia coli Nissle 1917 | 1.00 | ECOLIN_RS09270 | | multidrug efflux MATE transporter MdtK | 1.00 | ECOLIN_RS24240 | | FtsH protease activity modulator HflK | — | — |
| Escherichia coli ECOR27 | 1.00 | NOLOHH_17880 | mdtK | multidrug efflux MATE transporter MdtK | 1.00 | NOLOHH_04510 | hflK | FtsH protease activity modulator HflK | — | — |
| Escherichia coli ECRC62 | 1.00 | BNILDI_16670 | mdtK | multidrug efflux MATE transporter MdtK | 1.00 | BNILDI_06980 | hflK | FtsH protease activity modulator HflK | — | — |
| Escherichia coli ECRC101 | 1.00 | MCAODC_18050 | mdtK | multidrug efflux MATE transporter MdtK | 1.00 | MCAODC_02760 | hflK | FtsH protease activity modulator HflK | — | — |
| Escherichia coli ECRC101 | 1.00 | OKFHMN_27360 | mdtK | multidrug efflux MATE transporter MdtK | 1.00 | OKFHMN_12245 | hflK | FtsH protease activity modulator HflK | — | — |
| Escherichia coli ECRC99 | 1.00 | KEDOAH_00750 | mdtK | multidrug efflux MATE transporter MdtK | 1.00 | KEDOAH_15910 | hflK | FtsH protease activity modulator HflK | — | — |
| Escherichia coli ECRC102 | 1.00 | NIAGMN_00705 | mdtK | multidrug efflux MATE transporter MdtK | 1.00 | NIAGMN_10095 | hflK | FtsH protease activity modulator HflK | — | — |
| Escherichia coli ECRC98 | 1.00 | JDDGAC_01950 | mdtK | multidrug efflux MATE transporter MdtK | 1.00 | JDDGAC_15885 | hflK | FtsH protease activity modulator HflK | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.92 | GFF3613 | | Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps | 0.83 | GFF827 | | HflK protein | low | > 78 |
| Enterobacter sp. TBS_079 | 0.91 | MPMX20_01973 | | Multidrug resistance protein MdtK | 0.74 | MPMX20_00455 | | Modulator of FtsH protease HflK | 0.25 | 73 |
| Klebsiella michiganensis M5al | 0.89 | BWI76_RS16535 | | MATE family efflux transporter | 0.74 | BWI76_RS02545 | | protease modulator HflK | low | > 92 |
| Enterobacter asburiae PDN3 | 0.89 | EX28DRAFT_1660 | | putative efflux protein, MATE family | 0.81 | EX28DRAFT_3371 | | HflK protein | low | > 76 |
| Serratia liquefaciens MT49 | 0.77 | IAI46_11210 | | MATE family efflux transporter | 0.69 | IAI46_01635 | | FtsH protease activity modulator HflK | low | > 86 |
| Pantoea sp. MT58 | 0.76 | IAI47_10820 | | MATE family efflux transporter | 0.67 | IAI47_02600 | | FtsH protease activity modulator HflK | low | > 76 |
| Pectobacterium carotovorum WPP14 | 0.73 | HER17_RS09220 | | MATE family efflux transporter | 0.70 | HER17_RS02595 | | FtsH protease activity modulator HflK | 0.74 | 25 |
| Dickeya dianthicola 67-19 | 0.73 | HGI48_RS12700 | | MATE family efflux transporter | 0.68 | HGI48_RS18535 | | FtsH protease activity modulator HflK | low | > 71 |
| Dickeya dianthicola ME23 | 0.73 | DZA65_RS13155 | | MATE family efflux transporter | 0.69 | DZA65_RS19670 | | FtsH protease activity modulator HflK | low | > 75 |
| Erwinia tracheiphila SCR3 | 0.72 | LU632_RS11170 | | MATE family efflux transporter | 0.67 | LU632_RS02065 | hflK | FtsH protease activity modulator HflK | low | > 74 |
| Rahnella sp. WP5 | 0.72 | EX31_RS13855 | | MATE family efflux transporter | 0.64 | EX31_RS08810 | | FtsH protease activity modulator HflK | low | > 89 |
| Vibrio cholerae E7946 ATCC 55056 | 0.56 | CSW01_07735 | | multidrug resistance protein NorM | 0.46 | CSW01_01845 | | protease modulator HflK | low | > 62 |
| Shewanella sp. ANA-3 | 0.50 | Shewana3_2039 | | MATE efflux family protein (RefSeq) | 0.46 | Shewana3_0599 | | HflK protein (RefSeq) | low | > 73 |
| Shewanella loihica PV-4 | 0.50 | Shew_2037 | | MATE efflux family protein (RefSeq) | 0.45 | Shew_0568 | | HflK protein (RefSeq) | low | > 60 |
| Shewanella oneidensis MR-1 | 0.50 | SO2295 | | MATE efflux family protein (NCBI ptt file) | 0.45 | SO0605 | hflK | hflK protein (NCBI ptt file) | low | > 76 |
| Shewanella amazonensis SB2B | 0.49 | Sama_1761 | | MATE efflux family protein (RefSeq) | 0.46 | Sama_3023 | | hflK protein (RefSeq) | low | > 62 |
| Pseudomonas sp. S08-1 | 0.43 | OH686_02075 | | Na(+)/drug antiporter, MATE family of MDR efflux pumps | 0.32 | OH686_09460 | | HflK protein | low | > 80 |
| Alteromonas macleodii MIT1002 | 0.42 | MIT1002_02233 | | Na(+)/drug antiporter | 0.45 | MIT1002_03786 | | Modulator of FtsH protease HflK | low | > 70 |
| Pseudomonas fluorescens SBW25 | 0.41 | PFLU_RS07610 | | MATE family efflux transporter | 0.36 | PFLU_RS02580 | | FtsH protease activity modulator HflK | low | > 109 |
| Pseudomonas fluorescens GW456-L13 | 0.41 | PfGW456L13_4049 | | Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps | 0.34 | PfGW456L13_152 | | HflK protein | low | > 87 |
| Pseudomonas fluorescens SBW25-INTG | 0.41 | PFLU_RS07610 | | MATE family efflux transporter | 0.36 | PFLU_RS02580 | | FtsH protease activity modulator HflK | low | > 109 |
| Pseudomonas fluorescens FW300-N2E3 | 0.41 | AO353_00550 | | MATE family efflux transporter | 0.35 | AO353_13155 | | hypothetical protein | low | > 101 |
| Pseudomonas fluorescens FW300-N1B4 | 0.41 | Pf1N1B4_3892 | | Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps | 0.36 | Pf1N1B4_1410 | | HflK protein | — | — |
| Pseudomonas sp. RS175 | 0.41 | PFR28_01102 | | Multidrug resistance protein NorM | 0.35 | PFR28_05123 | | Modulator of FtsH protease HflK | low | > 88 |
| Pseudomonas simiae WCS417 | 0.41 | PS417_07530 | | multidrug transporter | 0.35 | PS417_02500 | | membrane protein | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.41 | Pf6N2E2_2298 | | Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps | 0.34 | Pf6N2E2_3612 | | HflK protein | low | > 103 |
| Pseudomonas fluorescens FW300-N2C3 | 0.41 | AO356_02370 | | MATE family efflux transporter | 0.35 | AO356_08645 | | hypothetical protein | low | > 104 |
| Pseudomonas stutzeri RCH2 | 0.40 | Psest_2549 | | putative efflux protein, MATE family | 0.34 | Psest_0685 | | HflK protein | — | — |
| Marinobacter adhaerens HP15 | 0.35 | HP15_3913 | | multidrug resistance protein NorM | 0.33 | HP15_2497 | | HflK | low | > 73 |
| Dyella japonica UNC79MFTsu3.2 | 0.31 | ABZR86_RS12525 | | MATE family efflux transporter | 0.25 | ABZR86_RS08355 | | FtsH protease activity modulator HflK | low | > 74 |
| Rhodanobacter denitrificans FW104-10B01 | 0.30 | LRK54_RS11085 | | MATE family efflux transporter | 0.28 | LRK54_RS00620 | | FtsH protease activity modulator HflK | low | > 59 |
| Rhodanobacter denitrificans MT42 | 0.30 | LRK55_RS10790 | | MATE family efflux transporter | 0.28 | LRK55_RS00390 | | FtsH protease activity modulator HflK | low | > 63 |
| Rhodanobacter sp. FW510-T8 | 0.29 | OKGIIK_12790 | norM | MATE family efflux transporter | 0.28 | OKGIIK_06640 | hflK | FtsH protease activity modulator HflK | low | > 52 |
| Kangiella aquimarina DSM 16071 | 0.26 | B158DRAFT_2495 | | putative efflux protein, MATE family | 0.28 | B158DRAFT_1954 | | protease FtsH subunit HflK | low | > 40 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.24 | Xcc-8004.4760.1 | | Multidrug and toxin extrusion (MATE) family efflux pump YdhE/NorM | 0.22 | Xcc-8004.3955.1 | | HflK protein | 0.38 | 55 |
| Ralstonia sp. UNC404CL21Col | 0.23 | ABZR87_RS10730 | | MATE family efflux transporter | 0.29 | ABZR87_RS10950 | | FtsH protease activity modulator HflK | 0.43 | 19 |
| Cupriavidus basilensis FW507-4G11 | 0.22 | RR42_RS13335 | | multidrug transporter MatE | 0.28 | RR42_RS13105 | | membrane protein | — | — |
| Ralstonia solanacearum UW163 | 0.22 | UW163_RS12570 | | MATE family efflux transporter | 0.30 | UW163_RS12775 | | FtsH protease activity modulator HflK | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.22 | RALBFv3_RS15100 | | MATE family efflux transporter | 0.30 | RALBFv3_RS15310 | | FtsH protease activity modulator HflK | low | > 76 |
| Variovorax sp. OAS795 | 0.22 | ABID97_RS14630 | | MATE family efflux transporter | 0.28 | ABID97_RS14260 | | FtsH protease activity modulator HflK | low | > 91 |
| Dinoroseobacter shibae DFL-12 | 0.22 | Dshi_0755 | | MATE efflux family protein (RefSeq) | 0.23 | Dshi_2736 | | HflK protein (RefSeq) | low | > 64 |
| Ralstonia solanacearum GMI1000 | 0.21 | RS_RS05915 | | MATE family efflux transporter | 0.28 | RS_RS06120 | | FtsH protease activity modulator HflK | low | > 80 |
| Sinorhizobium meliloti 1021 | 0.21 | SMc01211 | | hypothetical protein | 0.23 | SMc01441 | | membrane bound protease | low | > 103 |
| Ralstonia solanacearum PSI07 | 0.21 | RPSI07_RS18275 | | MATE family efflux transporter | 0.30 | RPSI07_RS18065 | | FtsH protease activity modulator HflK | low | > 81 |
| Rhodopseudomonas palustris CGA009 | 0.21 | TX73_004890 | | MATE family efflux transporter | 0.25 | TX73_018080 | | FtsH protease activity modulator HflK | low | > 86 |
| Paraburkholderia sabiae LMG 24235 | 0.21 | QEN71_RS04380 | | MATE family efflux transporter | 0.25 | QEN71_RS06010 | | FtsH protease activity modulator HflK | low | > 153 |
| Agrobacterium fabrum C58 | 0.20 | Atu2172 | | multidrug efflux protein | 0.22 | Atu2045 | | HFLK protein | low | > 89 |
| Rhizobium sp. OAE497 | 0.20 | ABIE40_RS12780 | | MATE family efflux transporter | 0.22 | ABIE40_RS11535 | | FtsH protease activity modulator HflK | low | > 107 |
| Phaeobacter inhibens DSM 17395 | 0.20 | PGA1_c21310 | | multidrug resistance protein NorM | 0.24 | PGA1_c23710 | | putative protein HflK | low | > 62 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.19 | Psyr_0073 | | Multi antimicrobial extrusion protein MatE | 0.34 | Psyr_0574 | | protease FtsH subunit HflK | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.19 | Psyr_0073 | | Multi antimicrobial extrusion protein MatE | 0.34 | Psyr_0574 | | protease FtsH subunit HflK | low | > 86 |
| Bosea sp. OAE506 | 0.19 | ABIE41_RS08515 | | MATE family efflux transporter | 0.23 | ABIE41_RS12850 | | FtsH protease activity modulator HflK | low | > 77 |
| Rhodospirillum rubrum S1H | 0.19 | Rru_A0697 | | Multi antimicrobial extrusion protein MatE (NCBI) | 0.22 | Rru_A2203 | | HflK (NCBI) | — | — |
| Variovorax sp. SCN45 | 0.19 | GFF1099 | | Na+-driven multidrug efflux pump | 0.27 | GFF1002 | | HflK protein | low | > 127 |
| Pseudomonas putida KT2440 | 0.19 | PP_5262 | | Probable multidrug resistance protein NorM | 0.33 | PP_4892 | | integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex | low | > 96 |
| Acidovorax sp. GW101-3H11 | 0.17 | Ac3H11_463 | | Multidrug and toxin extrusion (MATE) family efflux pump YdhE/NorM, homolog | 0.27 | Ac3H11_1801 | | HflK protein | low | > 79 |
| Dechlorosoma suillum PS | 0.16 | Dsui_1442 | | putative efflux protein, MATE family | 0.32 | Dsui_3135 | | HflK protein | — | — |
| Azospirillum sp. SherDot2 | 0.12 | MPMX19_01223 | | Multidrug resistance protein NorM | 0.22 | MPMX19_01251 | | Modulator of FtsH protease HflK | — | — |
Not shown: 22 genomes with orthologs for ECD_01634 only; 4 genomes with orthologs for ECD_04041 only