| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_11965 | | threonine synthase | 1.0 | CSW01_19025 | | LysR family transcriptional regulator | 0.53 | 4 |
| Rahnella sp. WP5 | 0.69 | EX31_RS03935 | | threonine synthase | 0.30 | EX31_RS16730 | | LysR family transcriptional regulator | low | > 89 |
| Klebsiella pneumoniae MKP103 | 0.68 | KDGMDA_12520 | | threonine synthase | 0.28 | KDGMDA_05040 | | LysR family transcriptional regulator | low | > 95 |
| Dickeya dianthicola 67-19 | 0.68 | HGI48_RS18335 | | threonine synthase | 0.26 | HGI48_RS19010 | | LysR family transcriptional regulator | low | > 71 |
| Klebsiella michiganensis M5al | 0.68 | BWI76_RS04255 | | threonine synthase | 0.27 | BWI76_RS27965 | | LysR family transcriptional regulator | low | > 92 |
| Erwinia amylovora T8 | 0.68 | OLJFJH_01485 | | threonine synthase | 0.25 | OLJFJH_06945 | | HTH-type transcriptional activator AaeR | low | > 58 |
| Pantoea sp. MT58 | 0.68 | IAI47_16205 | | threonine synthase | 0.28 | IAI47_20580 | | LysR family transcriptional regulator | low | > 76 |
| Pantoea agglomerans CFBP13505 P0401 | 0.68 | PagCFBP13505_RS21900 | | threonine synthase | 0.27 | PagCFBP13505_RS08890 | | LysR family transcriptional regulator | low | > 74 |
| Serratia liquefaciens MT49 | 0.68 | IAI46_03040 | | threonine synthase | 0.55 | IAI46_20610 | | LysR family transcriptional regulator | low | > 86 |
| Escherichia coli Nissle 1917 | 0.66 | ECOLIN_RS00020 | | threonine synthase | 0.25 | ECOLIN_RS20140 | | LysR family transcriptional regulator | low | > 55 |
| Escherichia coli ECOR38 | 0.66 | HEPCGN_09105 | thrC | threonine synthase | 0.25 | HEPCGN_15135 | yhjC | Uncharacterized HTH-type transcriptional regulator YhjC | low | > 88 |
| Escherichia coli BL21 | 0.66 | ECD_00004 | | L-threonine synthase | 0.25 | ECD_03369 | | LysR family putative transcriptional regulator | low | > 61 |
| Escherichia coli ECRC99 | 0.66 | KEDOAH_17055 | thrC | threonine synthase | 0.25 | KEDOAH_10390 | aaeR | HTH-type transcriptional activator AaeR | — | — |
| Escherichia coli BW25113 | 0.66 | b0004 | thrC | threonine synthase (NCBI) | 0.25 | b3521 | yhjC | predicted DNA-binding transcriptional regulator (RefSeq) | low | > 76 |
| Escherichia coli ECRC100 | 0.66 | OKFHMN_11100 | thrC | threonine synthase | 0.25 | OKFHMN_17760 | aaeR | HTH-type transcriptional activator AaeR | low | > 79 |
| Escherichia coli ECRC62 | 0.66 | BNILDI_08170 | thrC | threonine synthase | 0.25 | BNILDI_03360 | yhjC | Uncharacterized HTH-type transcriptional regulator YhjC | low | > 75 |
| Escherichia coli ECOR27 | 0.66 | NOLOHH_03430 | thrC | threonine synthase | 0.25 | NOLOHH_08195 | yhjC | Uncharacterized HTH-type transcriptional regulator YhjC | low | > 76 |
| Escherichia coli ECRC102 | 0.66 | NIAGMN_08950 | thrC | threonine synthase | 0.25 | NIAGMN_15520 | aaeR | HTH-type transcriptional activator AaeR | low | > 80 |
| Escherichia coli ECRC101 | 0.66 | MCAODC_01615 | thrC | threonine synthase | 0.25 | MCAODC_08280 | aaeR | HTH-type transcriptional activator AaeR | low | > 88 |
| Escherichia coli ECRC98 | 0.66 | JDDGAC_14695 | thrC | threonine synthase | 0.25 | JDDGAC_21385 | aaeR | HTH-type transcriptional activator AaeR | low | > 87 |
| Escherichia fergusonii Becca | 0.66 | EFB2_04039 | | Threonine synthase | 0.25 | EFB2_00287 | | HTH-type transcriptional regulator DmlR | low | > 86 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.66 | OHPLBJKB_03656 | | Threonine synthase | 0.25 | OHPLBJKB_00181 | | HTH-type transcriptional regulator DmlR | low | > 74 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.66 | GFF1080 | | Threonine synthase (EC 4.2.3.1) | 0.25 | GFF2141 | | LysR family transcriptional regulator QseA | low | > 78 |
| Alteromonas macleodii MIT1002 | 0.62 | MIT1002_03084 | | Threonine synthase | 0.76 | MIT1002_03329 | | D-malate degradation protein R | low | > 70 |
| Shewanella sp. ANA-3 | 0.60 | Shewana3_1141 | | threonine synthase (RefSeq) | 0.37 | Shewana3_3800 | | LysR family transcriptional regulator (RefSeq) | low | > 73 |
| Shewanella oneidensis MR-1 | 0.59 | SO3413 | thrC | threonine synthase (NCBI ptt file) | 0.38 | SO0369 | | transcriptional regulator, LysR family (NCBI ptt file) | low | > 76 |
| Lysobacter sp. OAE881 | 0.31 | ABIE51_RS17530 | | threonine synthase | 0.30 | ABIE51_RS12770 | | LysR family transcriptional regulator | low | > 62 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.31 | Xcc-8004.2954.1 | | Threonine synthase (EC 4.2.3.1) | 0.27 | Xcc-8004.52.1 | | transcriptional regulator lysR family | low | > 74 |
| Rhodanobacter denitrificans FW104-10B01 | 0.29 | LRK54_RS10355 | | threonine synthase | 0.32 | LRK54_RS12790 | | LysR family transcriptional regulator | low | > 59 |
| Rhodanobacter denitrificans MT42 | 0.28 | LRK55_RS09995 | | threonine synthase | 0.32 | LRK55_RS12490 | | LysR family transcriptional regulator | low | > 63 |
| Phaeobacter inhibens DSM 17395 | 0.28 | PGA1_c06310 | | threonine synthase ThrC | 0.29 | PGA1_c29160 | | HTH-type transcriptional regulator, LysR family | — | — |
| Rhodospirillum rubrum S1H | 0.28 | Rru_A3233 | | Threonine synthase (NCBI) | 0.35 | Rru_A1041 | | Transcriptional Regulator, LysR family (NCBI) | — | — |
| Rhodanobacter sp000427505 FW510-R12 | 0.27 | LRK53_RS03155 | | threonine synthase | 0.31 | LRK53_RS15810 | | LysR family transcriptional regulator | low | > 59 |
| Bosea sp. OAE506 | 0.27 | ABIE41_RS22985 | | threonine synthase | 0.30 | ABIE41_RS20280 | | LysR family transcriptional regulator | — | — |
| Azospirillum sp. SherDot2 | 0.27 | MPMX19_00671 | | Threonine synthase | 0.34 | MPMX19_04565 | | HTH-type transcriptional regulator PgrR | — | — |
| Caulobacter crescentus NA1000 | 0.27 | CCNA_03510 | | threonine synthase | 0.29 | CCNA_02602 | | LysR-family transcriptional regulator | — | — |
| Caulobacter crescentus NA1000 Δfur | 0.27 | CCNA_03510 | | threonine synthase | 0.29 | CCNA_02602 | | LysR-family transcriptional regulator | — | — |
| Dinoroseobacter shibae DFL-12 | 0.27 | Dshi_1146 | | threonine synthase (RefSeq) | 0.27 | Dshi_0123 | | transcriptional regulator, LysR family (RefSeq) | — | — |
| Marinobacter adhaerens HP15 | 0.26 | HP15_765 | | threonine synthase | 0.31 | HP15_936 | | transcriptional regulator, LysR family protein | — | — |
| Pseudomonas aeruginosa PA14 | 0.26 | IKLFDK_19070 | | threonine synthase | 0.31 | IKLFDK_11955 | | LysR family transcriptional regulator | low | > 100 |
| Pseudomonas syringae pv. syringae B728a | 0.25 | Psyr_1291 | | L-threonine synthase | 0.32 | Psyr_2951 | | transcriptional regulator, LysR family | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.25 | Psyr_1291 | | L-threonine synthase | 0.32 | Psyr_2951 | | transcriptional regulator, LysR family | — | — |
| Pseudomonas sp. S08-1 | 0.25 | OH686_17765 | | threonine synthase | 0.31 | OH686_18145 | | Transcriptional regulator, LysR family, in formaldehyde detoxification operon | low | > 80 |
| Pseudomonas putida KT2440 | 0.25 | PP_1471 | | Threonine synthase | 0.32 | PP_3811 | | Transcriptional regulator, LysR family | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.25 | AO353_04350 | | threonine synthase | 0.31 | AO353_22295 | | LysR family transcriptional regulator | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.25 | Pf6N2E2_3142 | | Threonine synthase (EC 4.2.3.1) | 0.32 | Pf6N2E2_259 | | Transcriptional regulator, LysR family | — | — |
| Pseudomonas simiae WCS417 | 0.25 | PS417_22880 | | threonine synthase | 0.32 | PS417_16085 | | LysR family transcriptional regulator | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.25 | AO356_06370 | | threonine synthase | 0.31 | AO356_21990 | | LysR family transcriptional regulator | — | — |
| Pseudomonas sp. BP01 | 0.25 | JOY50_RS11715 | thrC | threonine synthase | 0.32 | JOY50_RS04745 | | LysR family transcriptional regulator | — | — |
| Pseudomonas stutzeri RCH2 | 0.25 | Psest_3125 | | threonine synthase | 0.31 | Psest_2163 | | Transcriptional regulator | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.25 | Pf1N1B4_3014 | | Threonine synthase (EC 4.2.3.1) | 0.32 | Pf1N1B4_5905 | | Transcriptional regulator, LysR family | — | — |
| Pseudomonas fluorescens SBW25 | 0.25 | PFLU_RS24545 | | threonine synthase | 0.33 | PFLU_RS18050 | | LysR family transcriptional regulator | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.25 | PFLU_RS24545 | | threonine synthase | 0.33 | PFLU_RS18050 | | LysR family transcriptional regulator | — | — |
| Pseudomonas lactucae CFBP13502 | 0.25 | GEMAOFIL_04726 | | Threonine synthase | 0.32 | GEMAOFIL_02593 | | HTH-type transcriptional regulator DmlR | low | > 93 |
| Pseudomonas segetis P6 | 0.25 | MPMX49_01578 | | Threonine synthase | 0.29 | MPMX49_03437 | | HTH-type transcriptional regulator DmlR | low | > 75 |
| Pseudomonas sp. RS175 | 0.25 | PFR28_00334 | | Threonine synthase | 0.30 | PFR28_00531 | | HTH-type transcriptional regulator DmlR | — | — |
| Pseudomonas sp. DMC3 | 0.25 | GFF1990 | | Threonine synthase | 0.32 | GFF943 | | HTH-type transcriptional regulator DmlR | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.24 | PfGW456L13_1724 | | Threonine synthase (EC 4.2.3.1) | 0.32 | PfGW456L13_3857 | | Transcriptional regulator, LysR family | — | — |
| Ralstonia sp. UNC404CL21Col | 0.24 | ABZR87_RS05865 | | threonine synthase | 0.29 | ABZR87_RS21445 | | LysR family transcriptional regulator | low | > 80 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.24 | A4249_RS00020 | | threonine synthase | 0.27 | A4249_RS06710 | | LysR family transcriptional regulator | low | > 48 |
| Magnetospirillum magneticum AMB-1 | 0.24 | AMB_RS17140 | | threonine synthase | 0.31 | AMB_RS01140 | | LysR family transcriptional regulator | — | — |
| Methylophilus sp. DMC18 | 0.23 | GFF1164 | | Threonine synthase | 0.31 | GFF2818 | | HTH-type transcriptional regulator DmlR | — | — |
| Castellaniella sp019104865 MT123 | 0.23 | ABCV34_RS02300 | | threonine synthase | 0.33 | ABCV34_RS01420 | | LysR family transcriptional regulator | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.23 | Ga0059261_1999 | | threonine synthase | 0.27 | Ga0059261_3700 | | Transcriptional regulator | low | > 68 |
| Variovorax sp. SCN45 | 0.22 | GFF2800 | | Threonine synthase (EC 4.2.3.1) | 0.29 | GFF6589 | | Transcriptional regulator, LysR family | — | — |
| Dechlorosoma suillum PS | 0.22 | Dsui_2904 | | threonine synthase | 0.32 | Dsui_2353 | | transcriptional regulator | — | — |
| Paraburkholderia graminis OAS925 | 0.22 | ABIE53_002027 | | threonine synthase | 0.31 | ABIE53_004366 | | DNA-binding transcriptional LysR family regulator | — | — |
| Herbaspirillum seropedicae SmR1 | 0.20 | HSERO_RS10470 | | threonine synthase | 0.32 | HSERO_RS02935 | | LysR family transcriptional regulator | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.20 | RR42_RS12535 | | threonine synthase | 0.32 | RR42_RS04600 | | LysR family transcriptional regulator | — | — |
| Ralstonia solanacearum UW163 | 0.18 | UW163_RS13325 | | threonine synthase | 0.32 | UW163_RS06915 | | LysR family transcriptional regulator | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.18 | RALBFv3_RS15880 | | threonine synthase | 0.32 | RALBFv3_RS06700 | | LysR family transcriptional regulator | — | — |
Not shown: 38 genomes with orthologs for CSW01_11965 only; 1 genomes with orthologs for CSW01_19025 only