| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_19080 | | alkene reductase | 1.0 | CSW01_15165 | | DNA-binding response regulator | 0.57 | 17 |
| Shewanella loihica PV-4 | 0.69 | Shew_0507 | | NADH:flavin oxidoreductase/NADH oxidase (RefSeq) | 0.40 | Shew_0097 | | two component transcriptional regulator (RefSeq) | low | > 60 |
| Shewanella oneidensis MR-1 | 0.68 | SO4153 | | N-ethylmaleimide reductase, putative (NCBI ptt file) | 0.39 | SO4428 | | DNA-binding response regulator (NCBI ptt file) | low | > 76 |
| Enterobacter sp. TBS_079 | 0.59 | MPMX20_02166 | | N-ethylmaleimide reductase | 0.40 | MPMX20_02319 | | Transcriptional regulatory protein CusR | low | > 85 |
| Enterobacter asburiae PDN3 | 0.59 | EX28DRAFT_1386 | | NADH:flavin oxidoreductases, Old Yellow Enzyme family | 0.41 | EX28DRAFT_1165 | | heavy metal response regulator | low | > 76 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.56 | GFF2159 | | N-ethylmaleimide reductase | 0.40 | GFF1120 | | DNA-binding heavy metal response regulator | low | > 90 |
| Alteromonas macleodii MIT1002 | 0.52 | MIT1002_01213 | | N-ethylmaleimide reductase | 0.47 | MIT1002_03097 | | Transcriptional activator protein CopR | low | > 70 |
| Pseudomonas stutzeri RCH2 | 0.52 | Psest_0753 | | NADH:flavin oxidoreductases, Old Yellow Enzyme family | 0.40 | Psest_0611 | | heavy metal response regulator | low | > 67 |
| Pantoea agglomerans CFBP13505 P0401 | 0.52 | PagCFBP13505_RS14310 | | alkene reductase | 0.36 | PagCFBP13505_RS14010 | | response regulator transcription factor HprR | low | > 74 |
| Paraburkholderia sabiae LMG 24235 | 0.50 | QEN71_RS38950 | | alkene reductase | 0.39 | QEN71_RS15305 | | heavy metal response regulator transcription factor | low | > 153 |
| Pseudomonas putida KT2440 | 0.50 | PP_2486 | | NADH-dependent flavin oxidoreductase, Oye family | 0.42 | PP_1438 | | response regulator | low | > 96 |
| Pseudomonas aeruginosa MRSN321 | 0.49 | DY961_RS02325 | | alkene reductase | 0.40 | DY961_RS03005 | | heavy metal response regulator transcription factor | low | > 100 |
| Pseudomonas aeruginosa PA14 | 0.49 | IKLFDK_14895 | | alkene reductase | 0.40 | IKLFDK_14215 | | DNA-binding response regulator | low | > 98 |
| Pseudomonas aeruginosa PUPa3 | 0.49 | DQ20_RS33265 | | alkene reductase | 0.40 | DQ20_RS32585 | | heavy metal response regulator transcription factor | low | > 101 |
| Pseudomonas simiae WCS417 | 0.49 | PS417_11190 | | oxidoreductase | 0.42 | PS417_11825 | | transcriptional regulator | 0.17 | 18 |
| Pseudomonas fluorescens SBW25 | 0.49 | PFLU_RS11775 | | alkene reductase | 0.42 | PFLU_RS12570 | | response regulator transcription factor | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.49 | PFLU_RS11775 | | alkene reductase | 0.42 | PFLU_RS12570 | | response regulator transcription factor | low | > 109 |
| Pseudomonas sp. DMC3 | 0.49 | GFF2798 | | N-ethylmaleimide reductase | 0.41 | GFF1578 | | Transcriptional regulatory protein CusR | low | > 89 |
| Pseudomonas lactucae CFBP13502 | 0.48 | GEMAOFIL_02538 | | N-ethylmaleimide reductase | 0.42 | GEMAOFIL_02648 | | Transcriptional regulatory protein CusR | low | > 96 |
| Paraburkholderia graminis OAS925 | 0.48 | ABIE53_001750 | | N-ethylmaleimide reductase | 0.36 | ABIE53_005703 | | two-component system copper resistance phosphate regulon response regulator CusR | low | > 113 |
| Ralstonia solanacearum GMI1000 | 0.48 | RS_RS06020 | | alkene reductase | 0.50 | RS_RS24075 | | DNA-binding response regulator | low | > 80 |
| Ralstonia solanacearum PSI07 | 0.48 | RPSI07_RS18165 | | alkene reductase | 0.50 | RPSI07_RS06365 | | DNA-binding response regulator | low | > 81 |
| Pseudomonas sp. SVBP6 | 0.47 | COO64_RS09205 | | alkene reductase | 0.42 | COO64_RS16580 | | heavy metal response regulator transcription factor | low | > 93 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.47 | GFF3624 | | N-ethylmaleimide reductase (EC 1.-.-.-) | 0.36 | GFF3273 | | Putative two-component system response regulator YedW | low | > 78 |
| Escherichia coli Nissle 1917 | 0.46 | ECOLIN_RS09200 | | N-ethylmaleimide reductase | 0.39 | ECOLIN_RS03125 | | copper response regulator transcription factor CusR | — | — |
| Escherichia coli ECRC101 | 0.46 | MCAODC_17975 | nemA | N-ethylmaleimide reductase | 0.39 | MCAODC_26920 | cusR | copper response regulator transcription factor CusR | low | > 87 |
| Escherichia coli ECRC100 | 0.46 | OKFHMN_27435 | nemA | N-ethylmaleimide reductase | 0.39 | OKFHMN_07705 | cusR | copper response regulator transcription factor CusR | low | > 79 |
| Escherichia fergusonii Becca | 0.46 | EFB2_02342 | | N-ethylmaleimide reductase | 0.39 | EFB2_03523 | | Transcriptional regulatory protein CusR | low | > 86 |
| Escherichia coli ECRC98 | 0.46 | JDDGAC_02025 | nemA | N-ethylmaleimide reductase | 0.39 | JDDGAC_11350 | cusR | copper response regulator transcription factor CusR | low | > 87 |
| Escherichia coli ECRC102 | 0.46 | NIAGMN_00630 | nemA | N-ethylmaleimide reductase | 0.39 | NIAGMN_05760 | cusR | copper response regulator transcription factor CusR | low | > 80 |
| Escherichia coli ECOR38 | 0.46 | HEPCGN_05820 | nemA | N-ethylmaleimide reductase | 0.39 | HEPCGN_00585 | cusR | copper response regulator transcription factor CusR | low | > 88 |
| Escherichia coli ECOR27 | 0.46 | NOLOHH_17955 | nemA | N-ethylmaleimide reductase | 0.39 | NOLOHH_24085 | cusR | copper response regulator transcription factor CusR | low | > 76 |
| Escherichia coli BL21 | 0.46 | ECD_01620 | | chromate reductase, quinone reductase, FMN-linked; N-Ethylmaleimide reductase; old yellow enzyme | 0.39 | ECD_00532 | | response regulator in two-component regulatory system with CusS | low | > 61 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.46 | OHPLBJKB_02075 | | N-ethylmaleimide reductase | 0.39 | OHPLBJKB_03138 | | Transcriptional regulatory protein CusR | low | > 74 |
| Escherichia coli ECRC62 | 0.46 | BNILDI_16745 | nemA | N-ethylmaleimide reductase | 0.39 | BNILDI_22095 | cusR | copper response regulator transcription factor CusR | low | > 75 |
| Escherichia coli BW25113 | 0.46 | b1650 | nemA | N-ethylmaleimide reductase, FMN-linked (NCBI) | 0.39 | b0571 | cusR | DNA-binding response regulator in two-component regulatory system with CusS (NCBI) | low | > 76 |
| Acinetobacter baumannii LAC-4 | 0.46 | RR41_RS16240 | | alkene reductase | 0.44 | RR41_RS02755 | | heavy metal response regulator transcription factor | low | > 55 |
| Klebsiella pneumoniae MKP103 | 0.46 | KDGMDA_23420 | | alkene reductase | 0.41 | KDGMDA_00710 | | copper/silver response regulator transcription factor SilR | low | > 95 |
| Escherichia coli ECRC99 | 0.46 | KEDOAH_00675 | nemA | N-ethylmaleimide reductase | 0.39 | KEDOAH_20265 | cusR | copper response regulator transcription factor CusR | — | — |
| Serratia liquefaciens MT49 | 0.46 | IAI46_11280 | | alkene reductase | 0.39 | IAI46_16745 | | heavy metal response regulator transcription factor | low | > 87 |
| Acinetobacter radioresistens SK82 | 0.46 | MPMX26_00886 | | N-ethylmaleimide reductase | 0.44 | MPMX26_03114 | | Transcriptional regulatory protein CusR | low | > 36 |
| Dickeya dianthicola 67-19 | 0.45 | HGI48_RS12730 | | alkene reductase | 0.40 | HGI48_RS03485 | | heavy metal response regulator transcription factor | low | > 71 |
| Burkholderia phytofirmans PsJN | 0.45 | BPHYT_RS27240 | | N-ethylmaleimide reductase | 0.38 | BPHYT_RS25955 | | transcriptional regulator | low | > 109 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.45 | H281DRAFT_06090 | | N-ethylmaleimide reductase | 0.35 | H281DRAFT_01736 | | two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR | low | > 103 |
| Pseudomonas sp. BP01 | 0.45 | JOY50_RS12375 | | alkene reductase | 0.42 | JOY50_RS14720 | | heavy metal response regulator transcription factor | — | — |
| Klebsiella michiganensis M5al | 0.45 | BWI76_RS16475 | | alkene reductase | 0.32 | BWI76_RS18590 | | DNA-binding response regulator | low | > 92 |
| Dickeya dianthicola ME23 | 0.45 | DZA65_RS04670 | | alkene reductase | 0.41 | DZA65_RS03595 | | copper/silver response regulator transcription factor SilR | low | > 75 |
| Azospirillum sp. SherDot2 | 0.44 | MPMX19_04479 | | N-ethylmaleimide reductase | 0.47 | MPMX19_00794 | | Transcriptional activator protein CopR | low | > 112 |
| Agrobacterium fabrum C58 | 0.44 | Atu5445 | | oxidoreductase | 0.41 | Atu0629 | | two component response regulator | low | > 89 |
| Synechococcus elongatus PCC 7942 | 0.44 | Synpcc7942_0473 | | NADH:flavin oxidoreductase Old Yellow Enzyme family-like | 0.42 | Synpcc7942_1873 | | two component transcriptional regulator, winged helix family | 0.49 | 35 |
| Pectobacterium carotovorum WPP14 | 0.43 | HER17_RS14310 | | alkene reductase | 0.38 | HER17_RS13650 | | heavy metal response regulator transcription factor | low | > 75 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.43 | CA264_18315 | | alkene reductase | 0.44 | CA264_02615 | | DNA-binding response regulator | low | > 74 |
| Xanthobacter sp. DMC5 | 0.43 | GFF2396 | | N-ethylmaleimide reductase | 0.45 | GFF3127 | | Transcriptional regulatory protein CusR | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.43 | Pf6N2E2_1345 | | NADH:flavin oxidoreductases, Old Yellow Enzyme family | 0.41 | Pf6N2E2_504 | | DNA-binding response regulator | low | > 103 |
| Pseudomonas fluorescens FW300-N1B4 | 0.43 | Pf1N1B4_4194 | | 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) | 0.42 | Pf1N1B4_4267 | | DNA-binding response regulator | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.43 | AO356_25340 | | NADH:flavin oxidoreductase | 0.42 | AO356_23125 | | transcriptional regulator | low | > 104 |
| Herbaspirillum seropedicae SmR1 | 0.43 | HSERO_RS15610 | | NADH:flavin oxidoreductase | 0.37 | HSERO_RS12420 | | transcriptional regulator | low | > 78 |
| Rhodopseudomonas palustris CGA009 | 0.42 | TX73_022825 | | alkene reductase | 0.43 | TX73_009945 | | response regulator transcription factor | low | > 86 |
| Pseudomonas fluorescens FW300-N2E3 | 0.42 | AO353_28430 | | N-ethylmaleimide reductase | 0.43 | AO353_17925 | | transcriptional regulator | low | > 101 |
| Variovorax sp. SCN45 | 0.42 | GFF3328 | | NADH:flavin oxidoreductases, Old Yellow Enzyme family | 0.41 | GFF4686 | | Copper-sensing two-component system response regulator CusR | low | > 127 |
| Sinorhizobium meliloti 1021 | 0.42 | SMc01227 | | glycerol trinitrate (GTN) reductase | 0.39 | SMc02366 | | transcriptional regulator | low | > 103 |
| Azospirillum brasilense Sp245 | 0.41 | AZOBR_RS04305 | | 1 2-oxophytodienoate reductase | 0.48 | AZOBR_RS10800 | | XRE family transcriptional regulator | low | > 97 |
| Rhizobium sp. OAE497 | 0.41 | ABIE40_RS12885 | | alkene reductase | 0.40 | ABIE40_RS05700 | | response regulator transcription factor | low | > 107 |
| Pseudomonas orientalis W4I3 | 0.41 | QF045_RS09550 | | alkene reductase | 0.43 | QF045_RS14560 | | response regulator transcription factor | low | > 93 |
| Pseudomonas segetis P6 | 0.40 | MPMX49_03751 | | N-ethylmaleimide reductase | 0.41 | MPMX49_00081 | | Transcriptional activator protein CzcR | low | > 75 |
| Dechlorosoma suillum PS | 0.40 | Dsui_1877 | | NADH:flavin oxidoreductase | 0.40 | Dsui_2644 | | heavy metal response regulator | low | > 51 |
| Acidovorax sp. GW101-3H11 | 0.40 | Ac3H11_4975 | | Oxidoreductase, FMN-binding | 0.39 | Ac3H11_4210 | | DNA-binding heavy metal response regulator | low | > 79 |
| Ralstonia solanacearum IBSBF1503 | 0.40 | RALBFv3_RS20595 | | alkene reductase | 0.50 | RALBFv3_RS17335 | | DNA-binding response regulator | low | > 76 |
| Ralstonia solanacearum UW163 | 0.40 | UW163_RS18580 | | alkene reductase | 0.50 | UW163_RS21815 | | DNA-binding response regulator | — | — |
| Pseudomonas sp. S08-1 | 0.39 | OH686_06200 | | NADH:flavin , Old Yellow Enzyme family | 0.41 | OH686_22680 | | Copper-sensing two-component system response regulator CusR | low | > 80 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.39 | Psyr_4053 | | NADH:flavin oxidoreductase/NADH oxidase | 0.42 | Psyr_3127 | | Response regulator receiver:Transcriptional regulatory protein, C-terminal | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.39 | Psyr_4053 | | NADH:flavin oxidoreductase/NADH oxidase | 0.42 | Psyr_3127 | | Response regulator receiver:Transcriptional regulatory protein, C-terminal | low | > 86 |
| Pseudomonas fluorescens GW456-L13 | 0.39 | PfGW456L13_4578 | | NADH:flavin oxidoreductases, Old Yellow Enzyme family | 0.40 | PfGW456L13_4017 | | Copper-sensing two-component system response regulator CusR | low | > 87 |
| Bosea sp. OAE506 | 0.39 | ABIE41_RS08040 | | alkene reductase | 0.52 | ABIE41_RS01150 | | response regulator transcription factor | low | > 77 |
| Rhodospirillum rubrum S1H | 0.38 | Rru_A0475 | | NADH:flavin oxidoreductase/NADH oxidase (NCBI) | 0.47 | Rru_A2913 | | Two component Transcriptional regulator, Winged helix family (NCBI) | low | > 58 |
| Sphingobium sp. HT1-2 | 0.37 | GFF3259 | | NADH:flavin oxidoreductases, Old Yellow Enzyme family | 0.40 | GFF2992 | | Two-component transcriptional response regulator SMc02366, LuxR family | low | > 95 |
| Magnetospirillum magneticum AMB-1 | 0.37 | AMB_RS16690 | | alkene reductase | 0.46 | AMB_RS14570 | | DNA-binding response regulator | — | — |
| Dickeya dadantii 3937 | 0.37 | DDA3937_RS14735 | | alkene reductase | 0.34 | DDA3937_RS03385 | | heavy metal response regulator transcription factor | low | > 74 |
| Marinobacter adhaerens HP15 | 0.23 | HP15_2651 | | NADH:flavin oxidoreductase/NADH oxidase | 0.48 | HP15_3484 | | DNA-binding response regulator | — | — |
| Lysobacter sp. OAE881 | 0.19 | ABIE51_RS06830 | | NADH:flavin oxidoreductase/NADH oxidase | 0.44 | ABIE51_RS04165 | | response regulator transcription factor | low | > 62 |
| Caulobacter crescentus NA1000 | 0.18 | CCNA_01879 | | NADH:flavin oxidoreductases, old yellow enzyme family | 0.54 | CCNA_01351 | | two-component response regulator protein | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.18 | CCNA_01879 | | NADH:flavin oxidoreductases, old yellow enzyme family | 0.54 | CCNA_01351 | | two-component response regulator protein | low | > 67 |
| Parabacteroides merdae CL09T00C40 | 0.16 | HMPREF1078_RS15680 | | NADH:flavin oxidoreductase | 0.40 | HMPREF1078_RS01665 | | response regulator transcription factor | low | > 61 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.16 | BT2067 | | putative NADH:flavin oxidoreductase (NCBI ptt file) | 0.39 | BT0682 | | two-component system response regulator (NCBI ptt file) | 0.17 | 36 |
| Phocaeicola dorei CL03T12C01 | 0.16 | ABI39_RS09980 | | NADH:flavin oxidoreductase | 0.37 | ABI39_RS05370 | | response regulator transcription factor | low | > 72 |
| Bacteroides ovatus ATCC 8483 | 0.15 | BACOVA_03314 | | oxidoreductase, FAD/FMN-binding protein | 0.39 | BACOVA_02385 | | response regulator receiver domain protein | low | > 96 |
Not shown: 13 genomes with orthologs for CSW01_19080 only; 17 genomes with orthologs for CSW01_15165 only