Conservation of cofitness between CSW01_07965 and CSW01_13550 in Vibrio cholerae E7946 ATCC 55056

86 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_07965 LysR family transcriptional regulator 1.0 CSW01_13550 O-succinylhomoserine (thiol)-lyase 0.61 5
Erwinia amylovora T8 0.38 OLJFJH_05375 transcriptional regulator 0.54 OLJFJH_06095 cystathionine gamma-synthase low > 58
Pectobacterium carotovorum WPP14 0.36 HER17_RS18045 LysR family transcriptional regulator 0.60 HER17_RS00910 cystathionine gamma-synthase low > 75
Rahnella sp. WP5 0.36 EX31_RS04240 LysR family transcriptional regulator 0.56 EX31_RS14215 cystathionine gamma-synthase low > 89
Dickeya dadantii 3937 0.36 DDA3937_RS03225 LysR family transcriptional regulator 0.59 DDA3937_RS00950 cystathionine gamma-synthase low > 74
Dickeya dianthicola ME23 0.35 DZA65_RS03420 LysR family transcriptional regulator 0.58 DZA65_RS21470 cystathionine gamma-synthase low > 75
Dickeya dianthicola 67-19 0.35 HGI48_RS03375 LysR family transcriptional regulator 0.58 HGI48_RS20425 cystathionine gamma-synthase low > 71
Pantoea agglomerans CFBP13505 P0401 0.35 PagCFBP13505_RS12040 LysR family transcriptional regulator 0.56 PagCFBP13505_RS18460 cystathionine gamma-synthase low > 74
Klebsiella michiganensis M5al 0.35 BWI76_RS16740 transcriptional regulator 0.58 BWI76_RS00785 cystathionine gamma-synthase low > 92
Enterobacter asburiae PDN3 0.34 EX28DRAFT_2404 Transcriptional regulator 0.59 EX28DRAFT_4411 cystathionine gamma-synthase (EC 2.5.1.48) low > 76
Pantoea sp. MT58 0.34 IAI47_21735 LysR family transcriptional regulator 0.55 IAI47_00880 cystathionine gamma-synthase low > 76
Enterobacter sp. TBS_079 0.34 MPMX20_01221 HTH-type transcriptional regulator BenM 0.59 MPMX20_04531 Cystathionine gamma-synthase low > 85
Klebsiella pneumoniae MKP103 0.34 KDGMDA_23755 transcriptional regulator 0.59 KDGMDA_09295 cystathionine gamma-synthase low > 95
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.32 GFF3076 LysR family transcriptional regulator STM3121 0.59 GFF2323 Cystathionine gamma-synthase (EC 2.5.1.48) low > 78
Rhizobium sp. OAE497 0.31 ABIE40_RS01530 LysR family transcriptional regulator 0.27 ABIE40_RS02340 O-succinylhomoserine sulfhydrylase low > 107
Paraburkholderia sabiae LMG 24235 0.30 QEN71_RS38685 LysR family transcriptional regulator 0.25 QEN71_RS17685 O-succinylhomoserine sulfhydrylase low > 153
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.386.1 LysR family transcriptional regulator STM3121 0.53 Xcc-8004.1596.1 hypothetical protein low > 74
Paraburkholderia bryophila 376MFSha3.1 0.29 H281DRAFT_01885 DNA-binding transcriptional regulator, LysR family 0.26 H281DRAFT_06059 O-succinylhomoserine sulfhydrylase low > 103
Paraburkholderia graminis OAS925 0.29 ABIE53_004883 DNA-binding transcriptional LysR family regulator 0.26 ABIE53_004817 O-succinylhomoserine sulfhydrylase low > 113
Burkholderia phytofirmans PsJN 0.29 BPHYT_RS10210 LysR family transcriptional regulator 0.26 BPHYT_RS33835 O-succinylhomoserine sulfhydrylase — —
Pseudomonas sp. BP01 0.28 JOY50_RS09345 LysR family transcriptional regulator 0.34 JOY50_RS01570 PLP-dependent aspartate aminotransferase family protein low > 84
Pseudomonas aeruginosa PA14 0.28 IKLFDK_28390 LysR family transcriptional regulator 0.37 IKLFDK_23420 cystathionine gamma-synthase 0.34 6
Pseudomonas aeruginosa MRSN321 0.28 DY961_RS10965 LysR family transcriptional regulator 0.37 DY961_RS21980 cystathionine gamma-synthase low > 100
Pseudomonas aeruginosa PUPa3 0.28 DQ20_RS51110 LysR family transcriptional regulator 0.37 DQ20_RS37320 cystathionine gamma-synthase low > 101
Cupriavidus basilensis FW507-4G11 0.28 RR42_RS12375 LysR family transcriptional regulator 0.26 RR42_RS06465 O-acetylhomoserine aminocarboxypropyltransferase low > 128
Pseudomonas stutzeri RCH2 0.28 Psest_3707 Transcriptional regulator 0.32 Psest_2578 O-succinylhomoserine sulfhydrylase low > 67
Pseudomonas syringae pv. syringae B728a 0.27 Psyr_0421 transcriptional regulator, LysR family 0.30 Psyr_1669 O-succinylhomoserine sulfhydrylase low > 86
Pseudomonas putida KT2440 0.27 PP_5071 putative DNA-binding transcriptional regulator 0.34 PP_4594 putative Cystathionine gamma-synthase low > 96
Pseudomonas syringae pv. syringae B728a ΔmexB 0.27 Psyr_0421 transcriptional regulator, LysR family 0.30 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.44 27
Pseudomonas sp. SVBP6 0.27 COO64_RS13110 LysR family transcriptional regulator 0.37 COO64_RS14890 cystathionine gamma-synthase low > 93
Pseudomonas orientalis W4I3 0.27 QF045_RS05080 LysR substrate-binding domain-containing protein 0.36 QF045_RS15175 cystathionine gamma-synthase low > 93
Pseudomonas simiae WCS417 0.27 PS417_02020 LysR family transcriptional regulator 0.32 PS417_11735 methionine gamma-lyase low > 88
Herbaspirillum seropedicae SmR1 0.27 HSERO_RS17295 LysR family transcriptional regulator 0.22 HSERO_RS18310 O-acetylhomoserine aminocarboxypropyltransferase low > 78
Pseudomonas sp. RS175 0.27 PFR28_05019 HTH-type transcriptional regulator BenM 0.30 PFR28_02810 O-succinylhomoserine sulfhydrylase low > 88
Pseudomonas fluorescens FW300-N2E2 0.26 Pf6N2E2_3735 LysR family transcriptional regulator YnfL 0.30 Pf6N2E2_77 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 103
Pseudomonas fluorescens SBW25 0.26 PFLU_RS02065 LysR family transcriptional regulator 0.36 PFLU_RS16625 cystathionine gamma-synthase low > 109
Pseudomonas fluorescens FW300-N2C3 0.26 AO356_09290 LysR family transcriptional regulator 0.30 AO356_21470 O-succinylhomoserine sulfhydrylase low > 104
Pseudomonas fluorescens SBW25-INTG 0.26 PFLU_RS02065 LysR family transcriptional regulator 0.36 PFLU_RS16625 cystathionine gamma-synthase low > 109
Pseudomonas lactucae CFBP13502 0.26 GEMAOFIL_00636 HTH-type transcriptional regulator BenM 0.37 GEMAOFIL_02861 Cystathionine beta-lyase low > 96
Serratia liquefaciens MT49 0.26 IAI46_11680 LysR family transcriptional regulator 0.59 IAI46_24540 cystathionine gamma-synthase low > 87
Pseudomonas fluorescens GW456-L13 0.26 PfGW456L13_255 LysR family transcriptional regulator YnfL 0.30 PfGW456L13_3934 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 87
Azospirillum brasilense Sp245 0.26 AZOBR_RS19665 LysR family transcripitonal regulator 0.27 AZOBR_RS11340 O-acetylhomoserine aminocarboxypropyltransferase 0.33 5
Pseudomonas sp. DMC3 0.25 GFF3108 HTH-type transcriptional regulator BenM 0.38 GFF3060 Cystathionine beta-lyase low > 89
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_1530 LysR family transcriptional regulator YnfL 0.38 Pf1N1B4_4890 Cystathionine gamma-lyase (EC 4.4.1.1) low > 87
Variovorax sp. SCN45 0.25 GFF286 Transcriptional regulator, LysR family 0.28 GFF3088 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.25 GFF103 LysR family transcriptional regulator YnfL 0.29 GFF301 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.35 82
Ralstonia solanacearum IBSBF1503 0.25 RALBFv3_RS17920 LysR family transcriptional regulator 0.25 RALBFv3_RS01870 O-acetylhomoserine aminocarboxypropyltransferase — —
Ralstonia solanacearum UW163 0.25 UW163_RS21220 LysR family transcriptional regulator 0.25 UW163_RS15180 O-acetylhomoserine aminocarboxypropyltransferase — —
Pseudomonas fluorescens FW300-N2E3 0.25 AO353_12600 LysR family transcriptional regulator 0.38 AO353_23295 cystathionine beta-lyase low > 101
Ralstonia solanacearum PSI07 0.25 RPSI07_RS05680 LysR family transcriptional regulator 0.25 RPSI07_RS15620 O-acetylhomoserine aminocarboxypropyltransferase low > 81
Ralstonia solanacearum GMI1000 0.24 RS_RS23100 LysR family transcriptional regulator 0.25 RS_RS07865 O-acetylhomoserine aminocarboxypropyltransferase low > 80
Acinetobacter baumannii LAC-4 0.24 RR41_RS11480 LysR family transcriptional regulator 0.31 RR41_RS12630 O-succinylhomoserine sulfhydrylase low > 55
Ralstonia sp. UNC404CL21Col 0.23 ABZR87_RS12870 LysR family transcriptional regulator 0.27 ABZR87_RS17575 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme low > 80
Escherichia coli BL21 0.23 ECD_01564 LysR family putative transcriptional regulator 0.59 ECD_03825 cystathionine gamma-synthase, PLP-dependent — —
Pedobacter sp. GW460-11-11-14-LB5 0.23 CA265_RS13490 LysR family transcriptional regulator 0.37 CA265_RS06375 cystathionine gamma-synthase low > 88
Escherichia coli ECRC99 0.23 KEDOAH_00370 ynfL Uncharacterized HTH-type transcriptional regulator YnfL 0.59 KEDOAH_14485 metB cystathionine gamma-synthase — —
Escherichia coli ECRC101 0.23 MCAODC_17675 ynfL Uncharacterized HTH-type transcriptional regulator YnfL 0.59 MCAODC_04175 metB cystathionine gamma-synthase low > 87
Escherichia coli ECRC62 0.23 BNILDI_17030 ynfL Uncharacterized HTH-type transcriptional regulator YnfL 0.59 BNILDI_05715 metB cystathionine gamma-synthase low > 75
Escherichia fergusonii Becca 0.23 EFB2_02397 Hca operon transcriptional activator HcaR 0.59 EFB2_04679 Cystathionine gamma-synthase low > 86
Agrobacterium fabrum C58 0.23 Atu4021 LysR family transcriptional regulator 0.27 Atu0432 O-succinylhomoserine sulfhydrylase low > 89
Escherichia coli ECRC98 0.23 JDDGAC_02325 ynfL Uncharacterized HTH-type transcriptional regulator YnfL 0.59 JDDGAC_17300 metB cystathionine gamma-synthase low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.23 OHPLBJKB_02131 Hca operon transcriptional activator HcaR 0.59 OHPLBJKB_04111 Cystathionine gamma-synthase low > 74
Escherichia coli ECOR38 0.23 HEPCGN_06110 ynfL Uncharacterized HTH-type transcriptional regulator YnfL 0.59 HEPCGN_12345 metB cystathionine gamma-synthase low > 88
Escherichia coli ECOR27 0.23 NOLOHH_18240 ynfL Uncharacterized HTH-type transcriptional regulator YnfL 0.59 NOLOHH_05820 metB cystathionine gamma-synthase low > 76
Escherichia coli ECRC102 0.23 NIAGMN_00340 ynfL Uncharacterized HTH-type transcriptional regulator YnfL 0.59 NIAGMN_11430 metB cystathionine gamma-synthase low > 80
Escherichia coli Nissle 1917 0.23 ECOLIN_RS08910 LysR family transcriptional regulator 0.59 ECOLIN_RS22725 cystathionine gamma-synthase — —
Escherichia coli BW25113 0.23 b1595 ynfL predicted DNA-binding transcriptional regulator (NCBI) 0.59 b3939 metB cystathionine gamma-synthase (NCBI) low > 76
Escherichia coli ECRC100 0.23 OKFHMN_27735 ynfL Uncharacterized HTH-type transcriptional regulator YnfL 0.59 OKFHMN_13675 metB cystathionine gamma-synthase low > 79
Sphingobium sp. HT1-2 0.23 GFF3022 Transcriptional regulator, LysR family 0.27 GFF3455 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 95
Rhodanobacter sp. FW510-T8 0.23 OKGIIK_07285 lysR LysR family transcriptional regulator 0.55 OKGIIK_01515 metB cystathionine gamma-synthase low > 53
Rhodanobacter sp000427505 FW510-R12 0.23 LRK53_RS11345 LysR family transcriptional regulator 0.54 LRK53_RS04700 cystathionine gamma-synthase low > 59
Cellulophaga baltica 18 0.22 M666_RS12060 LysR substrate-binding domain-containing protein 0.39 M666_RS03785 cystathionine gamma-synthase low > 67
Rhodanobacter denitrificans FW104-10B01 0.22 LRK54_RS18015 LysR family transcriptional regulator 0.55 LRK54_RS05305 cystathionine gamma-synthase low > 59
Acidovorax sp. GW101-3H11 0.22 Ac3H11_4928 LysR family transcriptional regulator STM3121 0.31 Ac3H11_34 Methionine gamma-lyase (EC 4.4.1.11) low > 79
Rhodanobacter denitrificans MT42 0.22 LRK55_RS17870 LysR family transcriptional regulator 0.56 LRK55_RS05085 cystathionine gamma-synthase low > 63
Echinicola vietnamensis KMM 6221, DSM 17526 0.22 Echvi_0203 Transcriptional regulator 0.36 Echvi_2080 Cystathionine beta-lyases/cystathionine gamma-synthases low > 79
Dyella japonica UNC79MFTsu3.2 0.21 ABZR86_RS05585 LysR substrate-binding domain-containing protein 0.54 ABZR86_RS19030 cystathionine gamma-synthase low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.21 ABZR88_RS08630 LysR family transcriptional regulator 0.35 ABZR88_RS06685 cystathionine gamma-synthase low > 71
Acinetobacter radioresistens SK82 0.21 MPMX26_01690 HTH-type transcriptional regulator BenM 0.32 MPMX26_01645 O-succinylhomoserine sulfhydrylase low > 36
Dechlorosoma suillum PS 0.21 Dsui_3101 transcriptional regulator 0.35 Dsui_2042 cystathionine beta-lyase/cystathionine gamma-synthase low > 51
Caulobacter crescentus NA1000 0.20 CCNA_03140 LysR-family transcriptional regulator 0.31 CCNA_03271 methionine gamma-lyase low > 66
Caulobacter crescentus NA1000 Δfur 0.20 CCNA_03140 LysR-family transcriptional regulator 0.31 CCNA_03271 methionine gamma-lyase low > 67
Variovorax sp. OAS795 0.20 ABID97_RS17495 LysR family transcriptional regulator 0.27 ABID97_RS21630 O-succinylhomoserine sulfhydrylase — —
Rhodopseudomonas palustris CGA009 0.20 TX73_002855 LysR family transcriptional regulator 0.30 TX73_012185 PLP-dependent aspartate aminotransferase family protein low > 86
Pseudomonas segetis P6 0.19 ACVTMO_RS04005 LysR family transcriptional regulator 0.33 ACVTMO_RS05450 trans-sulfuration enzyme family protein low > 75
Azospirillum sp. SherDot2 0.19 MPMX19_03900 Hca operon transcriptional activator HcaR 0.32 MPMX19_06514 L-methionine gamma-lyase low > 112
Pontibacter actiniarum KMM 6156, DSM 19842 0.19 CA264_09455 LysR family transcriptional regulator 0.37 CA264_20315 cystathionine gamma-synthase low > 74

Not shown: 2 genomes with orthologs for CSW01_07965 only; 32 genomes with orthologs for CSW01_13550 only