| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_06545 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 1.0 | CSW01_06100 | | histidine utilization repressor | 0.48 | 15 |
| Bosea sp. OAE506 | 0.45 | ABIE41_RS21620 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.29 | ABIE41_RS23630 | | histidine utilization repressor | — | — |
| Serratia liquefaciens MT49 | 0.45 | IAI46_19100 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.44 | IAI46_10615 | | histidine utilization repressor | low | > 87 |
| Xanthobacter sp. DMC5 | 0.45 | GFF1029 | | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.14 | GFF474 | | HTH-type transcriptional repressor NagR | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.43 | QEN71_RS06305 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.43 | QEN71_RS23510 | | histidine utilization repressor | — | — |
| Enterobacter asburiae PDN3 | 0.43 | EX28DRAFT_0469 | | hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.41 | EX28DRAFT_2221 | | histidine utilization repressor, proteobacterial | low | > 76 |
| Pectobacterium carotovorum WPP14 | 0.42 | HER17_RS06265 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.13 | HER17_RS13540 | | GntR family transcriptional regulator | low | > 75 |
| Escherichia coli BW25113 | 0.42 | b2103 | thiD | phosphomethylpyrimidine kinase (NCBI) | 0.17 | b3375 | yhfR | putative transcriptional regulator (VIMSS) | low | > 76 |
| Escherichia coli ECRC102 | 0.42 | NIAGMN_22020 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.18 | NIAGMN_14915 | phoB | transcriptional regulator PhoB | low | > 80 |
| Escherichia coli ECRC99 | 0.42 | KEDOAH_04075 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.18 | KEDOAH_10995 | phoB | transcriptional regulator PhoB | — | — |
| Escherichia coli ECRC100 | 0.42 | OKFHMN_24075 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.18 | OKFHMN_17145 | phoB | transcriptional regulator PhoB | low | > 79 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.42 | OHPLBJKB_01607 | | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.17 | OHPLBJKB_00328 | | putative fructoselysine utilization operon transcriptional repressor | low | > 74 |
| Escherichia coli ECRC101 | 0.42 | MCAODC_21085 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.18 | MCAODC_07675 | phoB | transcriptional regulator PhoB | low | > 87 |
| Escherichia coli ECRC98 | 0.42 | JDDGAC_28185 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.18 | JDDGAC_20775 | phoB | transcriptional regulator PhoB | low | > 87 |
| Escherichia coli BL21 | 0.42 | ECD_02031 | | hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase | 0.17 | ECD_03225 | | putative DNA-binding transcriptional regulator | low | > 61 |
| Klebsiella pneumoniae MKP103 | 0.42 | KDGMDA_26425 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.40 | KDGMDA_16995 | | histidine utilization repressor | low | > 95 |
| Enterobacter sp. TBS_079 | 0.41 | MPMX20_03076 | | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.43 | MPMX20_01398 | | HTH-type transcriptional repressor NagR | low | > 85 |
| Klebsiella michiganensis M5al | 0.41 | BWI76_RS19375 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.41 | BWI76_RS08730 | | histidine utilization repressor | low | > 92 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.41 | H281DRAFT_00587 | | hydroxymethylpyrimidine kinase /phosphomethylpyrimidine kinase | 0.45 | H281DRAFT_04872 | | transcriptional regulator, histidine utilization repressor, GntR family | — | — |
| Rahnella sp. WP5 | 0.41 | EX31_RS20390 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.44 | EX31_RS06725 | | histidine utilization repressor | low | > 89 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.41 | GFF3834 | | Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) | 0.38 | GFF665 | | Histidine utilization repressor | low | > 78 |
| Burkholderia phytofirmans PsJN | 0.41 | BPHYT_RS12250 | | phosphomethylpyrimidine kinase | 0.44 | BPHYT_RS07560 | | histidine utilization repressor | — | — |
| Paraburkholderia graminis OAS925 | 0.40 | ABIE53_002529 | | hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.45 | ABIE53_001730 | | GntR family histidine utilization transcriptional repressor | — | — |
| Pantoea sp. MT58 | 0.39 | IAI47_06810 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.42 | IAI47_13270 | | histidine utilization repressor | low | > 76 |
| Sinorhizobium meliloti 1021 | 0.39 | SM_b20962 | | phoshomethylpyrimidine kinase | 0.40 | SMc00674 | | histidine utilization repressor transcription regulator protein | low | > 103 |
| Dickeya dadantii 3937 | 0.38 | DDA3937_RS15335 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.48 | DDA3937_RS15020 | | histidine utilization repressor | low | > 74 |
| Rhizobium sp. OAE497 | 0.38 | ABIE40_RS25930 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.43 | ABIE40_RS23900 | | histidine utilization repressor | low | > 107 |
| Pantoea agglomerans CFBP13505 P0401 | 0.38 | PagCFBP13505_RS00915 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.42 | PagCFBP13505_RS04050 | | histidine utilization repressor | low | > 74 |
| Dickeya dianthicola ME23 | 0.38 | DZA65_RS16235 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.47 | DZA65_RS15850 | | histidine utilization repressor | low | > 75 |
| Dickeya dianthicola 67-19 | 0.38 | HGI48_RS15410 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.47 | HGI48_RS15100 | | histidine utilization repressor | low | > 71 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.38 | Echvi_0215 | | phosphomethylpyrimidine kinase | 0.12 | Echvi_0410 | | Transcriptional regulators | low | > 79 |
| Castellaniella sp019104865 MT123 | 0.36 | ABCV34_RS14505 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.36 | ABCV34_RS12825 | | histidine utilization repressor | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.36 | GFF249 | | Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) | 0.37 | GFF3591 | | Histidine utilization repressor | low | > 90 |
| Methylophilus sp. DMC18 | 0.36 | GFF892 | | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.12 | GFF473 | | putative HTH-type transcriptional regulator YurK | low | > 43 |
| Rhodospirillum rubrum S1H | 0.35 | Rru_A1102 | | Phosphomethylpyrimidine kinase (NCBI) | 0.34 | Rru_A1294 | | Transcriptional Regulator, Histidine utilization repressor, GntR family (NCBI) | — | — |
| Acidovorax sp. GW101-3H11 | 0.35 | Ac3H11_1063 | | Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) | 0.40 | Ac3H11_2559 | | Histidine utilization repressor | — | — |
| Caulobacter crescentus NA1000 | 0.34 | CCNA_03331 | | phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase | 0.27 | CCNA_01013 | | histidine utilization repressor | — | — |
| Caulobacter crescentus NA1000 Δfur | 0.34 | CCNA_03331 | | phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase | 0.27 | CCNA_01013 | | histidine utilization repressor | — | — |
| Rhodanobacter sp000427505 FW510-R12 | 0.33 | LRK53_RS03825 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.36 | LRK53_RS08115 | | histidine utilization repressor | low | > 59 |
| Azospirillum brasilense Sp245 | 0.32 | AZOBR_RS07045 | | phosphomethylpyrimidine kinase | 0.15 | AZOBR_RS31515 | | GntR family transcriptional regulator | — | — |
| Azospirillum sp. SherDot2 | 0.32 | MPMX19_06182 | | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.43 | MPMX19_04937 | | Mannosyl-D-glycerate transport/metabolism system repressor MngR | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.32 | Xcc-8004.3091.1 | | hypothetical protein | 0.26 | Xcc-8004.3293.1 | | Histidine utilization repressor | low | > 74 |
| Desulfovibrio vulgaris Miyazaki F | 0.31 | DvMF_1376 | | phosphomethylpyrimidine kinase (RefSeq) | 0.14 | DvMF_0513 | | transcriptional regulator, GntR family (RefSeq) | — | — |
| Variovorax sp. OAS795 | 0.30 | ABID97_RS15330 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.41 | ABID97_RS03415 | | histidine utilization repressor | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.30 | RR42_RS01370 | | phosphomethylpyrimidine kinase | 0.38 | RR42_RS16925 | | histidine utilization repressor | — | — |
| Ralstonia sp. UNC404CL21Col | 0.29 | ABZR87_RS04830 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.41 | ABZR87_RS01035 | | histidine utilization repressor | — | — |
| Sphingobium sp. HT1-2 | 0.29 | GFF2573 | | Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) | 0.39 | GFF4449 | | Histidine utilization repressor | low | > 95 |
| Ralstonia solanacearum GMI1000 | 0.29 | RS_RS00495 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.38 | RS_RS13260 | | histidine utilization repressor | — | — |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.29 | A4249_RS15985 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.25 | A4249_RS06610 | | histidine utilization repressor | — | — |
| Ralstonia solanacearum PSI07 | 0.29 | RPSI07_RS23455 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.40 | RPSI07_RS11905 | | histidine utilization repressor | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.28 | RALBFv3_RS09905 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.39 | RALBFv3_RS05400 | | histidine utilization repressor | — | — |
| Ralstonia solanacearum UW163 | 0.28 | UW163_RS03675 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.39 | UW163_RS08225 | | histidine utilization repressor | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.25 | Psyr_4340 | | phosphomethylpyrimidine kinase, putative | 0.44 | Psyr_0366 | | transcriptional regulator, GntR family | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.25 | Psyr_4340 | | phosphomethylpyrimidine kinase, putative | 0.44 | Psyr_0366 | | transcriptional regulator, GntR family | low | > 86 |
| Sphingomonas koreensis DSMZ 15582 | 0.25 | Ga0059261_1961 | | hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.23 | Ga0059261_3966 | | Transcriptional regulators | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.25 | PFLU_RS26530 | | hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.44 | PFLU_RS01765 | | histidine utilization repressor | low | > 109 |
| Pseudomonas orientalis W4I3 | 0.25 | QF045_RS26885 | | hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.44 | QF045_RS04775 | | histidine utilization repressor | low | > 93 |
| Pseudomonas fluorescens FW300-N2C3 | 0.25 | AO356_15435 | | hydrogenase | 0.43 | AO356_09640 | | histidine utilization repressor | low | > 104 |
| Dechlorosoma suillum PS | 0.25 | Dsui_0662 | | phosphomethylpyrimidine kinase | 0.15 | Dsui_2210 | | transcriptional regulator | — | — |
| Pseudomonas fluorescens SBW25 | 0.25 | PFLU_RS26530 | | hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.44 | PFLU_RS01765 | | histidine utilization repressor | low | > 109 |
| Pseudomonas simiae WCS417 | 0.25 | PS417_24600 | | hydrogenase | 0.44 | PS417_01710 | | histidine utilization repressor | low | > 88 |
| Mycobacterium tuberculosis H37Rv | 0.24 | Rv0422c | | Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase) | 0.13 | Rv0792c | | Probable transcriptional regulatory protein (probably GntR-family) | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.24 | AO353_06350 | | hydrogenase | 0.44 | AO353_12240 | | histidine utilization repressor | low | > 101 |
| Pseudomonas sp. S08-1 | 0.24 | OH686_09185 | | Hydroxymethylpyrimidine phosphate kinase ThiD | 0.46 | OH686_16760 | | histidine utilization repressor | low | > 80 |
| Pseudomonas putida KT2440 | 0.23 | PP_4782 | | Phosphomethylpyrimidine kinase | 0.43 | PP_5035 | | Histidine utilization repressor | 0.47 | 36 |
| Pseudomonas fluorescens GW456-L13 | 0.23 | PfGW456L13_1385 | | Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) | 0.44 | PfGW456L13_329 | | Histidine utilization repressor | low | > 87 |
| Pseudomonas sp. DMC3 | 0.23 | GFF3905 | | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.43 | GFF4064 | | HTH-type transcriptional repressor NagR | low | > 89 |
| Pseudomonas sp. BP01 | 0.23 | JOY50_RS21745 | | hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.43 | JOY50_RS09510 | hutC | histidine utilization repressor | low | > 84 |
| Pseudomonas aeruginosa PUPa3 | 0.23 | DQ20_RS48300 | | hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.44 | DQ20_RS50745 | hutC;go_function=DNA-binding | histidine utilization repressor | low | > 101 |
| Pseudomonas sp. SVBP6 | 0.23 | COO64_RS15485 | | hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.42 | COO64_RS13400 | hutC | histidine utilization repressor | low | > 93 |
| Pseudomonas aeruginosa MRSN321 | 0.23 | DY961_RS12975 | | hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.44 | DY961_RS11350 | hutC;go_function=DNA-binding | histidine utilization repressor | low | > 100 |
| Pseudomonas aeruginosa PA14 | 0.23 | IKLFDK_20515 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.44 | IKLFDK_27995 | | histidine utilization repressor | low | > 98 |
| Acinetobacter baumannii LAC-4 | 0.23 | RR41_RS15160 | | hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.40 | RR41_RS00370 | | histidine utilization repressor | — | — |
| Pseudomonas sp. RS175 | 0.22 | PFR28_03843 | | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.43 | PFR28_04963 | | HTH-type transcriptional repressor NagR | low | > 88 |
| Pseudomonas segetis P6 | 0.22 | MPMX49_01077 | | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.47 | MPMX49_03959 | | HTH-type transcriptional repressor NagR | low | > 75 |
| Pseudomonas lactucae CFBP13502 | 0.21 | GEMAOFIL_05068 | | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.44 | GEMAOFIL_00565 | | HTH-type transcriptional repressor NagR | low | > 96 |
| Pseudomonas fluorescens FW300-N2E2 | 0.21 | Pf6N2E2_5024 | | Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) | 0.43 | Pf6N2E2_3807 | | Histidine utilization repressor | low | > 103 |
| Pseudomonas fluorescens FW300-N1B4 | 0.20 | Pf1N1B4_2718 | | Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) | 0.44 | Pf1N1B4_1590 | | Histidine utilization repressor | low | > 87 |
| Herbaspirillum seropedicae SmR1 | 0.20 | HSERO_RS02135 | | phosphomethylpyrimidine kinase | 0.17 | HSERO_RS14920 | | GntR family transcriptional regulator | — | — |
| Phaeobacter inhibens DSM 17395 | 0.17 | PGA1_c09030 | | phosphomethylpyrimidine kinase ThiD | 0.21 | PGA1_c36370 | | HTH-type transcriptional regulator, GntR family | low | > 62 |
Not shown: 31 genomes with orthologs for CSW01_06545 only; 6 genomes with orthologs for CSW01_06100 only