Conservation of cofitness between CSW01_02515 and CSW01_01420 in Vibrio cholerae E7946 ATCC 55056

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02515 transketolase 1.0 CSW01_01420 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 0.69 15
Escherichia coli HS(pFamp)R (ATCC 700891) 0.78 OHPLBJKB_00781 Transketolase 1 0.80 OHPLBJKB_04043 Bifunctional purine biosynthesis protein PurH — —
Klebsiella pneumoniae MKP103 0.78 KDGMDA_04465 transketolase 0.80 KDGMDA_10100 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Escherichia coli ECRC99 0.78 KEDOAH_08815 tkt transketolase 0.80 KEDOAH_14850 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Escherichia fergusonii Becca 0.78 EFB2_00966 Transketolase 1 0.80 EFB2_04604 Bifunctional purine biosynthesis protein PurH low > 86
Klebsiella michiganensis M5al 0.78 BWI76_RS24015 transketolase 0.80 BWI76_RS01615 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase — —
Escherichia coli ECRC62 0.78 BNILDI_09775 tkt transketolase 0.80 BNILDI_06065 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 75
Escherichia coli ECRC102 0.78 NIAGMN_17090 tkt transketolase 0.80 NIAGMN_11060 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 80
Escherichia coli ECRC100 0.78 OKFHMN_19325 tkt transketolase 0.80 OKFHMN_13310 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Escherichia coli BL21 0.78 ECD_02765 transketolase 1, thiamine triphosphate-binding 0.80 ECD_03883 IMP cyclohydrolase and phosphoribosylaminoimidazolecarboxamide formyltransferase low > 61
Escherichia coli ECRC101 0.78 MCAODC_09845 tkt transketolase 0.80 MCAODC_03810 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Escherichia coli ECOR38 0.78 HEPCGN_18630 tkt transketolase 0.80 HEPCGN_11950 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 88
Escherichia coli ECRC98 0.78 JDDGAC_22955 tkt transketolase 0.80 JDDGAC_16935 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 87
Escherichia coli BW25113 0.78 b2935 tktA transketolase 1, thiamin-binding (NCBI) 0.80 b4006 purH bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) low > 76
Escherichia coli ECOR27 0.78 NOLOHH_11230 tkt transketolase 0.80 NOLOHH_05455 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 76
Escherichia coli Nissle 1917 0.78 ECOLIN_RS16330 transketolase 0.80 ECOLIN_RS23100 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 55
Enterobacter sp. TBS_079 0.78 MPMX20_03780 Transketolase 1 0.79 MPMX20_00226 Bifunctional purine biosynthesis protein PurH 0.42 40
Enterobacter asburiae PDN3 0.78 EX28DRAFT_2974 transketolase, bacterial and yeast 0.80 EX28DRAFT_4545 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) — —
Dickeya dadantii 3937 0.78 DDA3937_RS18525 transketolase 0.79 DDA3937_RS01220 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.78 GFF3028 Transketolase (EC 2.2.1.1) 0.80 GFF4186 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) low > 78
Erwinia tracheiphila HP pepo 2.2 0.78 IJEDHG_03385 tkt transketolase 0.79 IJEDHG_10930 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Erwinia tracheiphila SCR3 0.78 LU632_RS05520 tkt transketolase 0.79 LU632_RS01020 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.41 53
Erwinia amylovora T8 0.78 OLJFJH_08645 transketolase 0.79 OLJFJH_06785 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 58
Dickeya dianthicola 67-19 0.77 HGI48_RS18450 transketolase 0.79 HGI48_RS01215 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Dickeya dianthicola ME23 0.77 DZA65_RS19585 transketolase 0.79 DZA65_RS01260 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pectobacterium carotovorum WPP14 0.77 HER17_RS02680 transketolase 0.78 HER17_RS20335 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 75
Pantoea agglomerans CFBP13505 P0401 0.77 PagCFBP13505_RS16020 transketolase 0.80 PagCFBP13505_RS22575 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 74
Pantoea sp. MT58 0.77 IAI47_03680 transketolase 0.80 IAI47_18040 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 76
Serratia liquefaciens MT49 0.76 IAI46_21045 transketolase 0.80 IAI46_01365 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Rahnella sp. WP5 0.76 EX31_RS21400 transketolase 0.81 EX31_RS16860 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.77 27
Shewanella sp. ANA-3 0.75 Shewana3_3353 transketolase (RefSeq) 0.77 Shewana3_0441 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) — —
Shewanella loihica PV-4 0.75 Shew_0752 transketolase (RefSeq) 0.79 Shew_3412 purH bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) — —
Shewanella oneidensis MR-1 0.74 SO0930 tkt transketolase (NCBI ptt file) 0.76 SO0442 purH phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI ptt file) — —
Alteromonas macleodii MIT1002 0.74 MIT1002_00861 Transketolase 1 0.77 MIT1002_03959 Bifunctional purine biosynthesis protein PurH — —
Pseudomonas sp. S08-1 0.73 OH686_10770 transketolase 0.71 OH686_07620 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas sp. SVBP6 0.72 COO64_RS17555 tkt transketolase 0.69 COO64_RS18305 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas sp. DMC3 0.72 GFF158 Transketolase 1 0.69 GFF3308 Bifunctional purine biosynthesis protein PurH — —
Pseudomonas putida KT2440 0.72 PP_4965 transketolase A 0.69 PP_4822 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas segetis P6 0.72 ACVTMO_RS03240 tkt transketolase 0.69 ACVTMO_RS20370 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas sp. RS175 0.71 PFR28_04188 Transketolase 1 0.69 PFR28_05214 Bifunctional purine biosynthesis protein PurH — —
Marinobacter adhaerens HP15 0.71 HP15_2913 bacterial transketolase 0.73 HP15_3227 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas sp. BP01 0.71 JOY50_RS09870 tkt transketolase 0.69 JOY50_RS17625 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas lactucae CFBP13502 0.71 GEMAOFIL_05420 Transketolase 1 0.69 GEMAOFIL_00820 Bifunctional purine biosynthesis protein PurH — —
Pseudomonas fluorescens FW300-N2C3 0.71 AO356_13680 transketolase 0.68 AO356_08225 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas fluorescens SBW25-INTG 0.71 PFLU_RS28095 transketolase 0.69 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Pseudomonas fluorescens SBW25 0.71 PFLU_RS28095 transketolase 0.69 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Pseudomonas fluorescens FW300-N2E2 0.71 Pf6N2E2_4655 Transketolase (EC 2.2.1.1) 0.68 Pf6N2E2_3519 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Pseudomonas fluorescens FW300-N2E3 0.71 AO353_07955 transketolase 0.68 AO353_13650 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Kangiella aquimarina DSM 16071 0.71 B158DRAFT_0510 transketolase, bacterial and yeast 0.73 B158DRAFT_0166 IMP cyclohydrolase (EC 3.5.4.10)/phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Pseudomonas orientalis W4I3 0.71 QF045_RS00840 transketolase 0.69 QF045_RS05975 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas aeruginosa PA14 0.71 IKLFDK_22685 transketolase 0.67 IKLFDK_29290 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas aeruginosa MRSN321 0.71 DY961_RS22760 tkt;go_component=cytoplasm|0005737||IEA;go_function=transketolase transketolase 0.67 DY961_RS10050 purH;go_function=catalytic bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas stutzeri RCH2 0.71 Psest_0328 transketolase, bacterial and yeast 0.68 Psest_1014 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas simiae WCS417 0.71 PS417_26440 transketolase 0.69 PS417_02940 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas fluorescens FW300-N1B4 0.70 Pf1N1B4_2397 Transketolase (EC 2.2.1.1) 0.69 Pf1N1B4_1315 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Pseudomonas fluorescens GW456-L13 0.68 PfGW456L13_1064 Transketolase (EC 2.2.1.1) 0.69 PfGW456L13_57 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Dechlorosoma suillum PS 0.65 Dsui_1561 transketolase 0.54 Dsui_1595 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Ralstonia sp. UNC404CL21Col 0.64 ABZR87_RS01440 transketolase 0.58 ABZR87_RS07640 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Methylophilus sp. DMC18 0.63 GFF2501 Transketolase 1 0.57 GFF1644 Bifunctional purine biosynthesis protein PurH — —
Rhodanobacter sp000427505 FW510-R12 0.63 LRK53_RS17110 transketolase 0.59 LRK53_RS01585 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 59
Dyella japonica UNC79MFTsu3.2 0.63 ABZR86_RS18655 transketolase 0.60 ABZR86_RS17045 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Rhodanobacter denitrificans FW104-10B01 0.63 LRK54_RS05750 transketolase 0.59 LRK54_RS06825 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Rhodanobacter denitrificans MT42 0.63 LRK55_RS05505 transketolase 0.59 LRK55_RS06570 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 63
Rhodanobacter sp. FW510-T8 0.63 OKGIIK_01095 tkt transketolase 0.59 OKGIIK_16805 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 53
Cupriavidus basilensis FW507-4G11 0.62 RR42_RS17575 transketolase 0.58 RR42_RS02720 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Ralstonia solanacearum IBSBF1503 0.62 RALBFv3_RS05870 transketolase 0.58 RALBFv3_RS11685 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Ralstonia solanacearum UW163 0.62 UW163_RS07755 transketolase 0.58 UW163_RS01900 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Ralstonia solanacearum GMI1000 0.61 RS_RS13760 transketolase 0.58 RS_RS02505 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase — —
Ralstonia solanacearum PSI07 0.61 RPSI07_RS11430 transketolase 0.58 RPSI07_RS21530 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Xanthobacter sp. DMC5 0.56 GFF2443 Transketolase 2 0.49 GFF3847 Bifunctional purine biosynthesis protein PurH — —
Variovorax sp. SCN45 0.54 GFF7176 Transketolase (EC 2.2.1.1) 0.56 GFF2146 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Sinorhizobium meliloti 1021 0.53 SMc02342 transketolase 0.45 SMc04088 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 103
Mucilaginibacter yixingensis YX-36 DSM 26809 0.48 ABZR88_RS02950 transketolase 0.33 ABZR88_RS16970 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Rhodopseudomonas palustris CGA009 0.46 TX73_024110 transketolase 0.50 TX73_000145 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Azospirillum brasilense Sp245 0.45 AZOBR_RS09010 transketolase 0.49 AZOBR_RS00225 purine biosynthesis protein purH — —
Magnetospirillum magneticum AMB-1 0.43 AMB_RS06990 transketolase 0.49 AMB_RS00505 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Dinoroseobacter shibae DFL-12 0.42 Dshi_1738 transketolase (RefSeq) 0.49 Dshi_0358 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) — —
Brevundimonas sp. GW460-12-10-14-LB2 0.41 A4249_RS00780 transketolase 0.42 A4249_RS13150 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Mycobacterium tuberculosis H37Rv 0.36 Rv1449c Transketolase Tkt (TK) 0.38 Rv0957 Probable bifunctional purine biosynthesis protein PurH: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) (5'-phosphoribosyl-5-aminoimidazole-4-carboxamide formyltransferase) + inosinemonophosphate cyclohydrolase (imp cyclohydrolase) (inosinicase) (imp synthetase) (ATIC) — —
Parabacteroides merdae CL09T00C40 0.29 HMPREF1078_RS08725 transketolase 0.33 HMPREF1078_RS16130 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Cellulophaga baltica 18 0.27 M666_RS17560 transketolase 0.32 M666_RS02365 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —

Not shown: 2 genomes with orthologs for CSW01_02515 only; 39 genomes with orthologs for CSW01_01420 only