Conservation of cofitness between CSW01_04590 and CSW01_00790 in Vibrio cholerae E7946 ATCC 55056

78 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_04590 transcriptional regulator GcvA 1.0 CSW01_00790 vitamin B12 transporter BtuB 0.53 19
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.73 GFF4865 Glycine cleavage system transcriptional activator GcvA 0.31 GFF2352 Outer membrane vitamin B12 receptor BtuB low > 78
Serratia liquefaciens MT49 0.72 IAI46_20340 transcriptional regulator GcvA 0.30 IAI46_24450 TonB-dependent vitamin B12 receptor BtuB low > 87
Rahnella sp. WP5 0.72 EX31_RS13110 transcriptional regulator GcvA 0.29 EX31_RS14135 TonB-dependent vitamin B12 receptor BtuB low > 89
Escherichia coli ECRC62 0.72 BNILDI_10505 gcvA glycine cleavage system transcriptional regulator GcvA 0.30 BNILDI_05850 btuB TonB-dependent vitamin B12 receptor BtuB low > 75
Escherichia coli BW25113 0.72 b2808 gcvA DNA-binding transcriptional dual regulator (NCBI) 0.30 b3966 btuB vitamin B12/cobalamin outer membrane transporter (NCBI) low > 76
Escherichia coli ECOR38 0.72 HEPCGN_19375 gcvA glycine cleavage system transcriptional regulator GcvA 0.30 HEPCGN_12185 btuB TonB-dependent vitamin B12 receptor BtuB low > 88
Escherichia coli Nissle 1917 0.72 ECOLIN_RS15650 glycine cleavage system transcriptional regulator GcvA 0.31 ECOLIN_RS22905 TonB-dependent vitamin B12 receptor BtuB low > 55
Escherichia fergusonii Becca 0.72 EFB2_01109 Glycine cleavage system transcriptional activator 0.28 EFB2_04644 Vitamin B12 transporter BtuB low > 86
Escherichia coli ECRC100 0.72 OKFHMN_20120 gcvA glycine cleavage system transcriptional regulator GcvA 0.30 OKFHMN_13530 btuB TonB-dependent vitamin B12 receptor BtuB low > 79
Escherichia coli HS(pFamp)R (ATCC 700891) 0.72 OHPLBJKB_00923 Glycine cleavage system transcriptional activator 0.30 OHPLBJKB_04084 Vitamin B12 transporter BtuB low > 74
Escherichia coli ECRC101 0.72 MCAODC_10645 gcvA glycine cleavage system transcriptional regulator GcvA 0.30 MCAODC_04030 btuB TonB-dependent vitamin B12 receptor BtuB low > 87
Escherichia coli ECRC99 0.72 KEDOAH_08010 gcvA glycine cleavage system transcriptional regulator GcvA 0.30 KEDOAH_14630 btuB TonB-dependent vitamin B12 receptor BtuB — —
Escherichia coli ECRC102 0.72 NIAGMN_17890 gcvA glycine cleavage system transcriptional regulator GcvA 0.30 NIAGMN_11280 btuB TonB-dependent vitamin B12 receptor BtuB low > 80
Escherichia coli ECRC98 0.72 JDDGAC_23785 gcvA glycine cleavage system transcriptional regulator GcvA 0.30 JDDGAC_17155 btuB TonB-dependent vitamin B12 receptor BtuB low > 87
Escherichia coli ECOR27 0.72 NOLOHH_12000 gcvA glycine cleavage system transcriptional regulator GcvA 0.30 NOLOHH_05675 btuB TonB-dependent vitamin B12 receptor BtuB low > 76
Enterobacter sp. TBS_079 0.71 MPMX20_03671 Glycine cleavage system transcriptional activator 0.28 MPMX20_04514 Vitamin B12 transporter BtuB 0.30 15
Klebsiella michiganensis M5al 0.71 BWI76_RS22955 transcriptional regulator GcvA 0.29 BWI76_RS00890 vitamin B12/cobalamin outer membrane transporter low > 92
Pantoea agglomerans CFBP13505 P0401 0.71 PagCFBP13505_RS16945 transcriptional regulator GcvA 0.31 PagCFBP13505_RS18385 TonB-dependent vitamin B12 receptor BtuB low > 74
Pantoea sp. MT58 0.71 IAI47_04025 transcriptional regulator GcvA 0.29 IAI47_00955 TonB-dependent vitamin B12 receptor BtuB low > 76
Dickeya dadantii 3937 0.71 DDA3937_RS05050 transcriptional regulator GcvA 0.32 DDA3937_RS00995 TonB-dependent vitamin B12 receptor BtuB low > 74
Dickeya dianthicola ME23 0.71 DZA65_RS05390 transcriptional regulator GcvA 0.30 DZA65_RS21425 TonB-dependent vitamin B12 receptor BtuB low > 75
Enterobacter asburiae PDN3 0.71 EX28DRAFT_2883 Transcriptional regulator 0.30 EX28DRAFT_4429 TonB-dependent vitamin B12 receptor low > 76
Dickeya dianthicola 67-19 0.71 HGI48_RS05050 transcriptional regulator GcvA 0.28 HGI48_RS20380 TonB-dependent vitamin B12 receptor BtuB low > 71
Pectobacterium carotovorum WPP14 0.71 HER17_RS16415 transcriptional regulator GcvA 0.29 HER17_RS00980 TonB-dependent vitamin B12 receptor BtuB low > 75
Alteromonas macleodii MIT1002 0.65 MIT1002_01520 Gcv operon activator 0.13 MIT1002_00716 Outer membrane cobalamin translocator low > 70
Klebsiella pneumoniae MKP103 0.63 KDGMDA_03515 Glycine cleavage system transcriptional activator 0.29 KDGMDA_09405 TonB-dependent vitamin B12 receptor BtuB low > 95
Azospirillum brasilense Sp245 0.39 AZOBR_RS20105 transcriptional regulator 0.08 AZOBR_RS19160 outer membrane cobalamin receptor protein BtuB 0.24 34
Pseudomonas fluorescens FW300-N2E2 0.37 Pf6N2E2_1560 Glycine cleavage system transcriptional activator GcvA 0.15 Pf6N2E2_4930 Outer membrane vitamin B12 receptor BtuB low > 103
Rhodospirillum rubrum S1H 0.37 Rru_A2214 Transcriptional Regulator, LysR family (NCBI) 0.11 Rru_A0488 TonB-dependent receptor (NCBI) low > 58
Paraburkholderia graminis OAS925 0.37 ABIE53_001336 LysR family glycine cleavage system transcriptional activator 0.16 ABIE53_001246 vitamin B12 transporter low > 113
Caulobacter crescentus NA1000 Δfur 0.37 CCNA_01174 LysR-family transcriptional regulator 0.11 CCNA_01826 vitamin B12 receptor low > 67
Caulobacter crescentus NA1000 0.37 CCNA_01174 LysR-family transcriptional regulator 0.11 CCNA_01826 vitamin B12 receptor low > 66
Brevundimonas sp. GW460-12-10-14-LB2 0.36 A4249_RS09680 transcriptional regulator GcvA 0.11 A4249_RS12105 TonB-dependent receptor 0.99 23
Ralstonia solanacearum GMI1000 0.35 RS_RS13815 transcriptional regulator GcvA 0.15 RS_RS12050 TonB-dependent receptor low > 80
Pseudomonas sp. SVBP6 0.34 COO64_RS14470 gcvA transcriptional regulator GcvA 0.16 COO64_RS15835 TonB-dependent receptor domain-containing protein low > 93
Burkholderia phytofirmans PsJN 0.34 BPHYT_RS11810 LysR family transcriptional regulator 0.16 BPHYT_RS04850 TonB-denpendent receptor low > 109
Ralstonia sp. UNC404CL21Col 0.34 ABZR87_RS01495 transcriptional regulator GcvA 0.16 ABZR87_RS00095 TonB-dependent receptor low > 80
Dyella japonica UNC79MFTsu3.2 0.33 ABZR86_RS20860 transcriptional regulator GcvA 0.20 ABZR86_RS10930 TonB-dependent vitamin B12 receptor low > 74
Ralstonia solanacearum PSI07 0.33 RPSI07_RS11375 transcriptional regulator GcvA 0.15 RPSI07_RS12875 TonB-dependent receptor low > 81
Ralstonia solanacearum IBSBF1503 0.32 RALBFv3_RS22095 transcriptional regulator GcvA 0.15 RALBFv3_RS04495 TonB-dependent receptor low > 76
Ralstonia solanacearum UW163 0.32 UW163_RS22635 transcriptional regulator GcvA 0.15 UW163_RS09175 TonB-dependent receptor — —
Paraburkholderia sabiae LMG 24235 0.32 QEN71_RS01310 transcriptional regulator GcvA 0.15 QEN71_RS25145 TonB-dependent receptor low > 153
Variovorax sp. SCN45 0.32 GFF1355 Transcriptional regulator, LysR family 0.17 GFF450 Outer membrane vitamin B12 receptor BtuB low > 127
Cupriavidus basilensis FW507-4G11 0.31 RR42_RS34190 LysR family transcriptional regulator 0.14 RR42_RS16140 TonB-dependent receptor low > 128
Pseudomonas aeruginosa PA14 0.31 IKLFDK_23190 LysR family transcriptional regulator 0.19 IKLFDK_06025 TonB-dependent vitamin B12 receptor low > 98
Pseudomonas sp. RS175 0.31 PFR28_04727 Glycine cleavage system transcriptional activator 0.15 PFR28_03938 Vitamin B12 transporter BtuB low > 88
Pseudomonas fluorescens FW300-N2C3 0.31 AO356_15125 LysR family transcriptional regulator 0.14 AO356_14985 TonB-dependent receptor low > 104
Pseudomonas aeruginosa PUPa3 0.31 DQ20_RS37090 LysR family transcriptional regulator 0.19 DQ20_RS46725 btuB;go_component=outer TonB-dependent vitamin B12 receptor low > 101
Variovorax sp. OAS795 0.31 ABID97_RS29015 transcriptional regulator GcvA 0.17 ABID97_RS17425 TonB-dependent receptor low > 91
Pseudomonas aeruginosa MRSN321 0.31 DY961_RS22230 LysR family transcriptional regulator 0.20 DY961_RS06055 btuB;go_component=outer TonB-dependent vitamin B12 receptor low > 100
Paraburkholderia bryophila 376MFSha3.1 0.31 H281DRAFT_02051 LysR family transcriptional regulator, glycine cleavage system transcriptional activator 0.16 H281DRAFT_00136 vitamin B12 transporter low > 103
Pseudomonas sp. S08-1 0.31 OH686_11695 Transcriptional regulator, LysR family 0.15 OH686_15755 Outer membrane vitamin B12 receptor BtuB low > 80
Sphingomonas koreensis DSMZ 15582 0.31 Ga0059261_4130 Transcriptional regulator 0.11 Ga0059261_0620 Outer membrane cobalamin receptor protein low > 68
Pseudomonas lactucae CFBP13502 0.30 GEMAOFIL_02417 Glycine cleavage system transcriptional activator 0.16 GEMAOFIL_05148 Vitamin B12 transporter BtuB low > 96
Pseudomonas sp. BP01 0.30 JOY50_RS09180 LysR family transcriptional regulator 0.14 JOY50_RS20070 TonB-dependent receptor domain-containing protein low > 84
Pseudomonas putida KT2440 0.30 PP_0661 putative Transcriptional regulator AmpR 0.15 PP_0525 TonB-dependent receptor, B12 family low > 96
Pseudomonas stutzeri RCH2 0.30 Psest_2739 Transcriptional regulator 0.20 Psest_3016 TonB-dependent vitamin B12 receptor low > 67
Pseudomonas simiae WCS417 0.30 PS417_23350 LysR family transcriptional regulator 0.16 PS417_25210 TonB-dependent receptor low > 88
Pseudomonas fluorescens FW300-N1B4 0.30 Pf1N1B4_1817 Glycine cleavage system transcriptional activator 0.15 Pf1N1B4_2660 Outer membrane vitamin B12 receptor BtuB low > 87
Pseudomonas fluorescens SBW25-INTG 0.30 PFLU_RS25165 LysR family transcriptional regulator 0.15 PFLU_RS26850 TonB-dependent receptor low > 109
Pseudomonas fluorescens SBW25 0.30 PFLU_RS25165 LysR family transcriptional regulator 0.15 PFLU_RS26850 TonB-dependent receptor low > 109
Pseudomonas segetis P6 0.29 ACVTMO_RS01970 LysR family transcriptional regulator 0.20 ACVTMO_RS09005 btuB TonB-dependent vitamin B12 receptor low > 75
Pseudomonas fluorescens GW456-L13 0.29 PfGW456L13_555 Glycine cleavage system transcriptional activator 0.16 PfGW456L13_1324 Outer membrane vitamin B12 receptor BtuB low > 87
Sphingobium sp. HT1-2 0.29 GFF1432 Transcriptional regulator, LysR family 0.12 GFF830 Outer membrane vitamin B12 receptor BtuB low > 95
Pseudomonas orientalis W4I3 0.29 QF045_RS03520 LysR family transcriptional regulator 0.15 QF045_RS27180 TonB-dependent receptor low > 93
Pseudomonas fluorescens FW300-N2E3 0.29 AO353_15505 LysR family transcriptional regulator 0.15 AO353_06660 TonB-dependent receptor low > 101
Pseudomonas sp. DMC3 0.29 GFF687 Glycine cleavage system transcriptional activator 0.16 GFF3838 Vitamin B12 transporter BtuB low > 89
Hydrogenophaga sp. GW460-11-11-14-LB1 0.28 GFF4407 Glycine cleavage system transcriptional activator 0.17 GFF3976 Outer membrane vitamin B12 receptor BtuB — —
Acidovorax sp. GW101-3H11 0.28 Ac3H11_902 Glycine cleavage system transcriptional activator 0.17 Ac3H11_985 Outer membrane vitamin B12 receptor BtuB — —
Castellaniella sp019104865 MT123 0.27 ABCV34_RS01790 LysR substrate-binding domain-containing protein 0.14 ABCV34_RS14545 TonB-dependent receptor low > 48
Rhodanobacter denitrificans FW104-10B01 0.27 LRK54_RS06630 transcriptional regulator GcvA 0.17 LRK54_RS07830 TonB-dependent vitamin B12 receptor low > 59
Rhodanobacter denitrificans MT42 0.27 LRK55_RS06375 transcriptional regulator GcvA 0.17 LRK55_RS07560 TonB-dependent vitamin B12 receptor low > 63
Rhodanobacter sp000427505 FW510-R12 0.26 LRK53_RS10360 LysR substrate-binding domain-containing protein 0.18 LRK53_RS00695 TonB-dependent vitamin B12 receptor low > 59
Lysobacter sp. OAE881 0.26 ABIE51_RS00605 LysR substrate-binding domain-containing protein 0.21 ABIE51_RS04930 TonB-dependent vitamin B12 receptor low > 62
Marinobacter adhaerens HP15 0.24 HP15_1669 transcriptional regulator, LysR family protein 0.15 HP15_3953 outer membrane receptor for transport of vitamin B low > 73
Xanthomonas campestris pv. campestris strain 8004 0.22 Xcc-8004.1418.1 Glycine cleavage system transcriptional activator 0.19 Xcc-8004.1388.1 Outer membrane vitamin B12 receptor BtuB — —
Xanthobacter sp. DMC5 0.22 GFF4114 HTH-type transcriptional regulator TrpI 0.14 GFF2992 Vitamin B12 transporter BtuB — —
Rhodanobacter sp. FW510-T8 0.18 OKGIIK_16180 Biotin transporter BioY 0.20 OKGIIK_05465 btuB TonB-dependent vitamin B12 receptor low > 53

Not shown: 25 genomes with orthologs for CSW01_04590 only; 4 genomes with orthologs for CSW01_00790 only