Conservation of cofitness between BT1607 and BT3733 in Bacteroides thetaiotaomicron VPI-5482

56 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT1607 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase (NCBI ptt file) 1.0 BT3733 arginosuccinate lyase (EC 4.3.2.1) (from data) 0.83 4
Bacteroides ovatus ATCC 8483 0.97 BACOVA_04344 tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein 0.96 BACOVA_03551 argininosuccinate lyase 0.88 42
Bacteroides stercoris CC31F 0.97 HMPREF1181_RS11305 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.92 HMPREF1181_RS03410 argininosuccinate lyase 0.81 14
Phocaeicola vulgatus CL09T03C04 0.96 HMPREF1058_RS15075 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.89 HMPREF1058_RS09585 argininosuccinate lyase low > 67
Phocaeicola dorei CL03T12C01 0.96 ABI39_RS10870 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.90 ABI39_RS07095 argininosuccinate lyase low > 72
Parabacteroides merdae CL09T00C40 0.84 HMPREF1078_RS14700 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.82 HMPREF1078_RS11315 argininosuccinate lyase 0.76 51
Pontibacter actiniarum KMM 6156, DSM 19842 0.68 CA264_07145 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase 0.65 CA264_06225 argininosuccinate lyase
Pedobacter sp. GW460-11-11-14-LB5 0.65 CA265_RS08950 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase 0.62 CA265_RS18485 arginosuccinate lyase (EC 4.3.2.1) (from data)
Echinicola vietnamensis KMM 6221, DSM 17526 0.65 Echvi_4643 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase 0.59 Echvi_3852 arginosuccinate lyase (EC 4.3.2.1) (from data)
Mucilaginibacter yixingensis YX-36 DSM 26809 0.64 ABZR88_RS09400 bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase 0.63 ABZR88_RS12070 argininosuccinate lyase
Bosea sp. OAE506 0.44 ABIE41_RS08995 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.25 ABIE41_RS08750 argininosuccinate lyase
Dechlorosoma suillum PS 0.44 Dsui_0093 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase 0.22 Dsui_0111 argininosuccinate lyase
Kangiella aquimarina DSM 16071 0.44 B158DRAFT_1028 methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)/5,10-methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) 0.31 B158DRAFT_1980 argininosuccinate lyase
Hydrogenophaga sp. GW460-11-11-14-LB1 0.44 GFF4894 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.23 GFF736 Argininosuccinate lyase (EC 4.3.2.1)
Erwinia tracheiphila SCR3 0.44 LU632_RS15195 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.26 LU632_RS19600 argH argininosuccinate lyase
Vibrio cholerae E7946 ATCC 55056 0.44 CSW01_09720 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.23 CSW01_13360 argininosuccinate lyase low > 62
Dickeya dianthicola 67-19 0.43 HGI48_RS15155 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.23 HGI48_RS00885 argininosuccinate lyase
Dickeya dadantii 3937 0.43 DDA3937_RS15075 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.25 DDA3937_RS20340 argininosuccinate lyase
Shewanella sp. ANA-3 0.43 Shewana3_2663 methenyltetrahydrofolate cyclohydrolase (RefSeq) 0.22 Shewana3_3901 argininosuccinate lyase (RefSeq)
Shewanella oneidensis MR-1 0.43 SO1792 folD methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase (NCBI ptt file) 0.22 SO0279 argH argininosuccinate lyase (NCBI ptt file)
Shewanella loihica PV-4 0.42 Shew_2510 methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq) 0.23 Shew_0206 argininosuccinate lyase (RefSeq)
Pantoea sp. MT58 0.42 IAI47_14320 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.25 IAI47_00920 argininosuccinate lyase
Ralstonia solanacearum GMI1000 0.42 RS_RS08040 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.21 RS_RS11865 argininosuccinate lyase
Pseudomonas putida KT2440 0.42 PP_1945 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.26 PP_0184 Argininosuccinate lyase low > 96
Pseudomonas syringae pv. syringae B728a 0.42 Psyr_2225 methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+) 0.26 Psyr_0065 argininosuccinate lyase
Pseudomonas syringae pv. syringae B728a ΔmexB 0.42 Psyr_2225 methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+) 0.26 Psyr_0065 argininosuccinate lyase
Synechococcus elongatus PCC 7942 0.41 Synpcc7942_0777 folD Methenyltetrahydrofolate cyclohydrolase 0.25 Synpcc7942_2475 argH argininosuccinate lyase
Paraburkholderia graminis OAS925 0.41 ABIE53_002796 methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase 0.23 ABIE53_001311 argininosuccinate lyase
Paraburkholderia sabiae LMG 24235 0.41 QEN71_RS05700 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.22 QEN71_RS24970 argininosuccinate lyase
Pseudomonas sp. S08-1 0.41 OH686_03670 Methenyltetrahydrofolate cyclohydrolase / Methylenetetrahydrofolate dehydrogenase (NADP+) 0.26 OH686_13885 argininosuccinate lyase
Shewanella amazonensis SB2B 0.41 Sama_1222 methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq) 0.23 Sama_0260 argininosuccinate lyase (RefSeq)
Pseudomonas fluorescens FW300-N2E3 0.41 AO353_20145 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase 0.26 AO353_09000 argininosuccinate lyase
Sinorhizobium meliloti 1021 0.41 SMc03059 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 0.22 SMc00725 argininosuccinate lyase
Castellaniella sp019104865 MT123 0.41 ABCV34_RS04175 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.22 ABCV34_RS03060 argininosuccinate lyase
Pseudomonas stutzeri RCH2 0.41 Psest_2301 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase 0.26 Psest_3751 argininosuccinate lyase
Pseudomonas simiae WCS417 0.40 PS417_17265 methenyltetrahydrofolate cyclohydrolase 0.26 PS417_27540 argininosuccinate lyase
Pseudomonas fluorescens FW300-N2E2 0.40 Pf6N2E2_2221 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.26 Pf6N2E2_4429 Argininosuccinate lyase (EC 4.3.2.1)
Pseudomonas fluorescens GW456-L13 0.40 PfGW456L13_2550 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.25 PfGW456L13_854 Argininosuccinate lyase (EC 4.3.2.1)
Pseudomonas sp. RS175 0.40 PFR28_01223 Bifunctional protein FolD protein 0.26 PFR28_04367 Argininosuccinate lyase
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_01775 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase 0.26 AO356_12780 argininosuccinate lyase
Pseudomonas fluorescens FW300-N1B4 0.40 Pf1N1B4_3943 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.25 Pf1N1B4_2183 Argininosuccinate lyase (EC 4.3.2.1)
Phaeobacter inhibens DSM 17395 0.40 PGA1_c06010 bifunctional protein FolD 0.22 PGA1_c03450 argininosuccinate lyase ArgH
Brevundimonas sp. GW460-12-10-14-LB2 0.40 A4249_RS06645 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.23 A4249_RS12555 argininosuccinate lyase
Rhizobium sp. OAE497 0.40 ABIE40_RS03150 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.22 ABIE40_RS17520 argininosuccinate lyase
Pseudomonas fluorescens SBW25 0.40 PFLU_RS19200 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.26 PFLU_RS29220 argininosuccinate lyase
Marinobacter adhaerens HP15 0.40 HP15_2187 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.26 HP15_243 argininosuccinate lyase
Pseudomonas fluorescens SBW25-INTG 0.40 PFLU_RS19200 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.26 PFLU_RS29220 argininosuccinate lyase
Sphingomonas koreensis DSMZ 15582 0.40 Ga0059261_2527 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase 0.21 Ga0059261_2049 argininosuccinate lyase
Rhodopseudomonas palustris CGA009 0.38 TX73_002145 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.20 TX73_024645 argininosuccinate lyase
Rhodanobacter denitrificans MT42 0.38 LRK55_RS18095 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.28 LRK55_RS02135 argininosuccinate lyase
Rhodanobacter denitrificans FW104-10B01 0.38 LRK54_RS00100 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.28 LRK54_RS02380 argininosuccinate lyase
Acinetobacter radioresistens SK82 0.38 MPMX26_00777 Bifunctional protein FolD protein 0.24 MPMX26_00185 Argininosuccinate lyase
Dyella japonica UNC79MFTsu3.2 0.38 ABZR86_RS05415 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.28 ABZR86_RS08695 arginosuccinate lyase (EC 4.3.2.1) (from data)
Dinoroseobacter shibae DFL-12 0.37 Dshi_1285 Methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq) 0.22 Dshi_3062 argininosuccinate lyase (RefSeq)
Rhodanobacter sp. FW510-T8 0.37 OKGIIK_07100 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.27 OKGIIK_09430 argH argininosuccinate lyase
Lysobacter sp. OAE881 0.36 ABIE51_RS09470 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.30 ABIE51_RS13380 argininosuccinate lyase
Xanthomonas campestris pv. campestris strain 8004 0.34 Xcc-8004.2390.1 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.27 Xcc-8004.2323.1 Argininosuccinate lyase (EC 4.3.2.1)

Not shown: 45 genomes with orthologs for BT1607 only; 0 genomes with orthologs for BT3733 only