Conservation of cofitness between BT0409 and BT0532 in Bacteroides thetaiotaomicron VPI-5482

64 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT0409 putative short-chain dehydrogenase (NCBI ptt file) 1.0 BT0532 anthranilate synthase component I (NCBI ptt file) 0.35 4
Bacteroides ovatus ATCC 8483 0.94 BACOVA_01762 hypothetical protein 0.96 BACOVA_03780 chorismate binding enzyme low > 94
Phocaeicola dorei CL03T12C01 0.82 ABI39_RS12400 SDR family oxidoreductase 0.77 ABI39_RS21050 anthranilate synthase component I family protein low > 72
Phocaeicola vulgatus CL09T03C04 0.81 HMPREF1058_RS16480 SDR family oxidoreductase 0.77 HMPREF1058_RS07175 anthranilate synthase component I family protein low > 67
Bacteroides stercoris CC31F 0.77 HMPREF1181_RS12415 SDR family oxidoreductase 0.72 HMPREF1181_RS15325 anthranilate synthase component I family protein low > 56
Pedobacter sp. GW460-11-11-14-LB5 0.53 CA265_RS15110 NAD(P)-dependent oxidoreductase 0.46 CA265_RS22890 anthranilate synthase component I low > 88
Mucilaginibacter yixingensis YX-36 DSM 26809 0.51 ABZR88_RS15830 SDR family NAD(P)-dependent oxidoreductase 0.46 ABZR88_RS16595 anthranilate synthase component I family protein
Fusobacterium nucleatum SB010 0.51 HUW76_08120 SDR family NAD(P)-dependent oxidoreductase 0.18 HUW76_10205 aminodeoxychorismate synthase component I low > 35
Desulfovibrio vulgaris Hildenborough JW710 0.49 DVU1784 oxidoreductase, short-chain dehydrogenase/reductase family (TIGR) 0.26 DVU0465 trpE anthranilate synthase, component I (TIGR) low > 55
Pontibacter actiniarum KMM 6156, DSM 19842 0.47 CA264_00460 NAD(P)-dependent oxidoreductase 0.48 CA264_05055 anthranilate synthase component I low > 74
Rhodospirillum rubrum S1H 0.47 Rru_A2127 Serine 3-dehydrogenase (NCBI) 0.27 Rru_A1891 Anthranilate synthase component I (NCBI) low > 58
Rahnella sp. WP5 0.46 EX31_RS07075 bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG 0.20 EX31_RS09955 anthranilate synthase component 1 low > 89
Echinicola vietnamensis KMM 6221, DSM 17526 0.46 Echvi_1820 Short-chain alcohol dehydrogenase of unknown specificity 0.45 Echvi_2504 Anthranilate/para-aminobenzoate synthases component I low > 79
Pseudomonas syringae pv. syringae B728a ΔmexB 0.45 Psyr_0602 Short-chain dehydrogenase/reductase SDR 0.26 Psyr_4609 anthranilate synthase, component I low > 86
Pseudomonas syringae pv. syringae B728a 0.45 Psyr_0602 Short-chain dehydrogenase/reductase SDR 0.26 Psyr_4609 anthranilate synthase, component I 0.47 1
Pectobacterium carotovorum WPP14 0.45 HER17_RS10705 bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG 0.20 HER17_RS10915 anthranilate synthase component 1 low > 75
Pseudomonas stutzeri RCH2 0.45 Psest_0101 Short-chain alcohol dehydrogenase of unknown specificity 0.26 Psest_3650 anthranilate synthase component I, non-proteobacterial lineages low > 67
Erwinia tracheiphila SCR3 0.45 LU632_RS11720 ydfG bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG 0.19 LU632_RS12755 anthranilate synthase component 1 low > 74
Pseudomonas fluorescens GW456-L13 0.45 PfGW456L13_117 Oxidoreductase, short chain dehydrogenase/reductase family 0.25 PfGW456L13_1217 Anthranilate synthase, aminase component (EC 4.1.3.27) low > 87
Pseudomonas fluorescens FW300-N2E3 0.44 AO353_13380 hypothetical protein 0.26 AO353_07230 anthranilate synthase low > 101
Pseudomonas fluorescens FW300-N1B4 0.44 Pf1N1B4_1376 Oxidoreductase, short chain dehydrogenase/reductase family 0.25 Pf1N1B4_2545 Anthranilate synthase, aminase component (EC 4.1.3.27) low > 87
Serratia liquefaciens MT49 0.44 IAI46_11720 bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG 0.19 IAI46_14020 anthranilate synthase component 1 low > 86
Dickeya dianthicola 67-19 0.44 HGI48_RS10690 bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG 0.19 HGI48_RS10485 anthranilate synthase component 1 low > 71
Pseudomonas fluorescens FW300-N2E2 0.44 Pf6N2E2_3575 Oxidoreductase, short chain dehydrogenase/reductase family 0.26 Pf6N2E2_4822 Anthranilate synthase, aminase component (EC 4.1.3.27) low > 103
Pseudomonas sp. RS175 0.44 PFR28_05158 Sulfoacetaldehyde reductase 0.26 PFR28_04047 Anthranilate synthase component 1
Pseudomonas fluorescens FW300-N2C3 0.44 AO356_08475 hypothetical protein 0.26 AO356_14420 anthranilate synthase low > 104
Paraburkholderia bryophila 376MFSha3.1 0.43 H281DRAFT_04724 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase 0.26 H281DRAFT_05715 anthranilate synthase, component I low > 103
Dickeya dadantii 3937 0.43 DDA3937_RS10695 bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG 0.19 DDA3937_RS10485 anthranilate synthase component 1 0.30 64
Pantoea sp. MT58 0.43 IAI47_09805 bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG 0.20 IAI47_08795 aminodeoxychorismate synthase component 1 low > 76
Xanthomonas campestris pv. campestris strain 8004 0.43 Xcc-8004.4903.1 Oxidoreductase 0.26 Xcc-8004.608.1 Anthranilate synthase, aminase component (EC 4.1.3.27) low > 74
Desulfovibrio vulgaris Miyazaki F 0.43 DvMF_0398 short-chain dehydrogenase/reductase SDR (RefSeq) 0.24 DvMF_1746 Anthranilate synthase (RefSeq) low > 51
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS26240 bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG 0.26 QEN71_RS27550 anthranilate synthase component I low > 153
Ralstonia solanacearum GMI1000 0.43 RS_RS03675 NAD(P)-dependent oxidoreductase 0.25 RS_RS14430 anthranilate synthase component I low > 80
Ralstonia sp. UNC404CL21Col 0.42 ABZR87_RS08960 bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG 0.25 ABZR87_RS02140 anthranilate synthase component I low > 80
Burkholderia phytofirmans PsJN 0.42 BPHYT_RS03720 malonic semialdehyde reductase 0.26 BPHYT_RS17390 anthranilate synthase subunit I low > 109
Enterobacter sp. TBS_079 0.42 MPMX20_02099 NADP-dependent 3-hydroxy acid dehydrogenase YdfG 0.21 MPMX20_02717 Aminodeoxychorismate synthase component 1 low > 85
Ralstonia solanacearum UW163 0.42 UW163_RS00665 NAD(P)-dependent oxidoreductase 0.25 UW163_RS07140 anthranilate synthase component I
Pseudomonas putida KT2440 0.42 PP_4862 3-hydroxy acid dehydrogenase, NADP-dependent / malonic semialdehyde reductase 0.26 PP_0417 Anthranilate synthase component 1 low > 96
Ralstonia solanacearum IBSBF1503 0.42 RALBFv3_RS12900 NAD(P)-dependent oxidoreductase 0.25 RALBFv3_RS06485 anthranilate synthase component I low > 76
Ralstonia solanacearum PSI07 0.42 RPSI07_RS20325 NAD(P)-dependent oxidoreductase 0.25 RPSI07_RS10755 anthranilate synthase component I
Enterobacter asburiae PDN3 0.42 EX28DRAFT_1450 Short-chain alcohol dehydrogenase of unknown specificity 0.20 EX28DRAFT_0747 aminodeoxychorismate synthase, component I, bacterial clade low > 76
Herbaspirillum seropedicae SmR1 0.41 HSERO_RS06135 malonic semialdehyde reductase 0.25 HSERO_RS19435 anthranilate synthase subunit I low > 78
Pseudomonas fluorescens SBW25 0.41 PFLU_RS02750 SDR family oxidoreductase 0.25 PFLU_RS27380 anthranilate synthase component I low > 109
Pseudomonas simiae WCS417 0.41 PS417_02680 hypothetical protein 0.25 PS417_25725 anthranilate synthase component I low > 88
Pseudomonas fluorescens SBW25-INTG 0.41 PFLU_RS02750 SDR family oxidoreductase 0.25 PFLU_RS27380 anthranilate synthase component I low > 109
Rhodanobacter denitrificans MT42 0.39 LRK55_RS08680 SDR family NAD(P)-dependent oxidoreductase 0.26 LRK55_RS11145 anthranilate synthase component I low > 63
Rhodanobacter sp. FW510-T8 0.39 OKGIIK_15640 NADP-dependent 3-hydroxy acid dehydrogenase 0.26 OKGIIK_12405 trpE anthranilate synthase component I low > 52
Rhodanobacter denitrificans FW104-10B01 0.39 LRK54_RS09150 SDR family NAD(P)-dependent oxidoreductase 0.26 LRK54_RS11415 anthranilate synthase component I low > 59
Magnetospirillum magneticum AMB-1 0.39 AMB_RS12070 NADP-dependent 3-hydroxy acid dehydrogenase 0.26 AMB_RS09175 anthranilate synthase component I
Castellaniella sp019104865 MT123 0.38 ABCV34_RS03925 SDR family NAD(P)-dependent oxidoreductase 0.24 ABCV34_RS10280 anthranilate synthase component I low > 48
Azospirillum sp. SherDot2 0.37 MPMX19_02817 Serine 3-dehydrogenase 0.28 MPMX19_00893 Anthranilate synthase component 1 low > 112
Sphingomonas koreensis DSMZ 15582 0.37 Ga0059261_2041 Short-chain alcohol dehydrogenase of unknown specificity 0.24 Ga0059261_0256 anthranilate synthase component I, non-proteobacterial lineages low > 68
Bosea sp. OAE506 0.34 ABIE41_RS08870 SDR family NAD(P)-dependent oxidoreductase 0.26 ABIE41_RS15730 anthranilate synthase component I
Mycobacterium tuberculosis H37Rv 0.32 Rv0484c Probable short-chain type oxidoreductase 0.23 Rv1609 Anthranilate synthase component I TrpE (glutamine amidotransferase)
Variovorax sp. SCN45 0.31 GFF4612 Short-chain dehydrogenase/reductase SDR 0.22 GFF5896 Anthranilate synthase, aminase component (EC 4.1.3.27) low > 127
Acinetobacter radioresistens SK82 0.30 MPMX26_00858 putative oxidoreductase 0.26 MPMX26_00199 Anthranilate synthase component 1 low > 36
Variovorax sp. OAS795 0.30 ABID97_RS05845 SDR family oxidoreductase 0.23 ABID97_RS05250 anthranilate synthase component I low > 91
Alteromonas macleodii MIT1002 0.29 MIT1002_02336 putative oxidoreductase 0.19 MIT1002_02008 Para-aminobenzoate synthase component 1 low > 70
Cupriavidus basilensis FW507-4G11 0.29 RR42_RS36075 oxidoreductase 0.25 RR42_RS18295 anthranilate synthase component I low > 128
Brevundimonas sp. GW460-12-10-14-LB2 0.28 A4249_RS03515 SDR family oxidoreductase 0.23 A4249_RS06155 anthranilate synthase component I low > 48
Lysobacter sp. OAE881 0.28 ABIE51_RS11295 SDR family oxidoreductase 0.25 ABIE51_RS04150 anthranilate synthase component I low > 62
Azospirillum brasilense Sp245 0.28 AZOBR_RS05975 oxidoreductase 0.27 AZOBR_RS07490 anthranilate synthase subunit I low > 97
Pseudomonas sp. S08-1 0.25 OH686_18360 Short-chain dehydrogenase/reductase SDR 0.27 OH686_15125 anthranilate synthase component I low > 80
Phaeobacter inhibens DSM 17395 0.20 PGA1_c08820 putative oxidoreductase 0.22 PGA1_c16860 anthranilate synthase component 1
Acidovorax sp. GW101-3H11 0.20 Ac3H11_2710 short-chain dehydrogenase/reductase SDR 0.24 Ac3H11_767 Anthranilate synthase, aminase component (EC 4.1.3.27) low > 79

Not shown: 23 genomes with orthologs for BT0409 only; 12 genomes with orthologs for BT0532 only