Conservation of cofitness between b0142 and b3389 in Escherichia coli BW25113

73 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0142 folK 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) 1.0 b3389 aroB 3-dehydroquinate synthase (NCBI) 0.60 4
Escherichia coli BL21 0.97 ECD_00141 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase 1.00 ECD_03241 3-dehydroquinate synthase — —
Escherichia coli ECRC62 0.97 BNILDI_08965 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 1.00 BNILDI_02615 aroB 3-dehydroquinate synthase — —
Escherichia coli ECOR27 0.97 NOLOHH_02705 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 1.00 NOLOHH_08905 aroB 3-dehydroquinate synthase — —
Escherichia coli ECOR38 0.97 HEPCGN_08310 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 1.00 HEPCGN_15935 aroB 3-dehydroquinate synthase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.97 OHPLBJKB_03520 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.99 OHPLBJKB_00314 3-dehydroquinate synthase — —
Escherichia fergusonii Becca 0.90 EFB2_03902 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 1.00 EFB2_00439 3-dehydroquinate synthase low > 86
Escherichia coli Nissle 1917 0.90 ECOLIN_RS00785 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.99 ECOLIN_RS19360 3-dehydroquinate synthase — —
Escherichia coli ECRC102 0.90 NIAGMN_08210 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 0.99 NIAGMN_14885 aroB 3-dehydroquinate synthase — —
Escherichia coli ECRC99 0.90 KEDOAH_17795 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 0.99 KEDOAH_11025 aroB 3-dehydroquinate synthase — —
Escherichia coli ECRC101 0.90 MCAODC_00875 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 0.99 MCAODC_07645 aroB 3-dehydroquinate synthase — —
Escherichia coli ECRC101 0.90 OKFHMN_10360 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 0.99 OKFHMN_17115 aroB 3-dehydroquinate synthase — —
Escherichia coli ECRC98 0.90 JDDGAC_13955 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 0.99 JDDGAC_20745 aroB 3-dehydroquinate synthase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.83 GFF90 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) 0.86 GFF630 3-dehydroquinate synthase (EC 4.2.3.4) — —
Klebsiella michiganensis M5al 0.79 BWI76_RS05000 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.85 BWI76_RS26085 3-dehydroquinate synthase — —
Enterobacter sp. TBS_079 0.79 MPMX20_00828 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.89 MPMX20_04278 3-dehydroquinate synthase — —
Enterobacter asburiae PDN3 0.78 EX28DRAFT_3731 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 0.88 EX28DRAFT_4153 3-dehydroquinate synthase (EC 4.2.3.4) — —
Rahnella sp. WP5 0.67 EX31_RS03265 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.84 EX31_RS04720 3-dehydroquinate synthase — —
Pectobacterium carotovorum WPP14 0.67 HER17_RS05565 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.79 HER17_RS01780 3-dehydroquinate synthase low > 75
Dickeya dadantii 3937 0.64 DDA3937_RS15950 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.81 DDA3937_RS19545 3-dehydroquinate synthase — —
Dickeya dianthicola 67-19 0.64 HGI48_RS16065 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.80 HGI48_RS19675 3-dehydroquinate synthase — —
Dickeya dianthicola ME23 0.64 DZA65_RS17150 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.80 DZA65_RS20760 3-dehydroquinate synthase — —
Pantoea sp. MT58 0.63 IAI47_15650 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.84 IAI47_01895 3-dehydroquinate synthase — —
Serratia liquefaciens MT49 0.63 IAI46_21225 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.81 IAI46_23700 3-dehydroquinate synthase — —
Erwinia tracheiphila SCR3 0.62 LU632_RS20095 folK 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.82 LU632_RS22865 aroB 3-dehydroquinate synthase — —
Vibrio cholerae E7946 ATCC 55056 0.61 CSW01_03140 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.63 CSW01_13300 3-dehydroquinate synthase — —
Pseudomonas stutzeri RCH2 0.56 Psest_0997 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 0.53 Psest_3713 3-dehydroquinate synthase — —
Pseudomonas sp. S08-1 0.54 OH686_17250 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.54 OH686_10015 3-dehydroquinate synthase — —
Alteromonas macleodii MIT1002 0.51 MIT1002_03693 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.60 MIT1002_00447 3-dehydroquinate synthase — —
Pseudomonas fluorescens FW300-N2E3 0.46 AO353_14390 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.54 AO353_12505 3-dehydroquinate synthase — —
Pseudomonas fluorescens SBW25 0.45 PFLU_RS25745 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.55 PFLU_RS02030 3-dehydroquinate synthase — —
Pseudomonas fluorescens SBW25-INTG 0.45 PFLU_RS25745 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.55 PFLU_RS02030 3-dehydroquinate synthase — —
Shewanella amazonensis SB2B 0.45 Sama_0777 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase (RefSeq) 0.62 Sama_3367 3-dehydroquinate synthase (RefSeq) — —
Marinobacter adhaerens HP15 0.44 HP15_325 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.53 HP15_480 3-dehydroquinate synthase — —
Pseudomonas sp. RS175 0.44 PFR28_03720 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.54 PFR28_05013 3-dehydroquinate synthase — —
Shewanella sp. ANA-3 0.42 Shewana3_3407 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (RefSeq) 0.61 Shewana3_3893 aroB 3-dehydroquinate synthase (RefSeq) — —
Kangiella aquimarina DSM 16071 0.42 B158DRAFT_0059 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 0.44 B158DRAFT_0764 3-dehydroquinate synthase (EC 4.2.3.4) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.41 Psyr_0829 7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK 0.54 Psyr_0409 3-dehydroquinate synthase — —
Pseudomonas syringae pv. syringae B728a 0.41 Psyr_0829 7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK 0.54 Psyr_0409 3-dehydroquinate synthase — —
Shewanella oneidensis MR-1 0.41 SO0871 folK-1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (NCBI ptt file) 0.61 SO0287 aroB 3-dehydroquinate synthase (NCBI ptt file) 0.63 73
Pseudomonas fluorescens FW300-N2C3 0.41 AO356_16065 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.55 AO356_09385 3-dehydroquinate synthase — —
Pseudomonas fluorescens GW456-L13 0.41 PfGW456L13_1522 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) 0.55 PfGW456L13_275 3-dehydroquinate synthase (EC 4.2.3.4) — —
Pseudomonas fluorescens FW300-N2E2 0.41 Pf6N2E2_5154 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) 0.55 Pf6N2E2_3754 3-dehydroquinate synthase (EC 4.2.3.4) — —
Pseudomonas fluorescens FW300-N1B4 0.40 Pf1N1B4_2855 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) 0.55 Pf1N1B4_1537 3-dehydroquinate synthase (EC 4.2.3.4) — —
Xanthomonas campestris pv. campestris strain 8004 0.40 Xcc-8004.3053.1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) 0.41 Xcc-8004.1615.1 3-dehydroquinate synthase (EC 4.2.3.4) — —
Pseudomonas simiae WCS417 0.39 PS417_23905 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.55 PS417_01985 3-dehydroquinate synthase — —
Dyella japonica UNC79MFTsu3.2 0.39 ABZR86_RS00810 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.42 ABZR86_RS10480 3-dehydroquinate synthase — —
Rhodanobacter denitrificans FW104-10B01 0.38 LRK54_RS15110 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.41 LRK54_RS04310 3-dehydroquinate synthase — —
Pseudomonas putida KT2440 0.37 PP_4698 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase 0.55 PP_5078 3-dehydroquinate synthase — —
Rhodanobacter denitrificans MT42 0.37 LRK55_RS14825 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.41 LRK55_RS04085 3-dehydroquinate synthase — —
Rhodanobacter sp. FW510-T8 0.36 OKGIIK_03880 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 0.42 OKGIIK_11185 aroB 3-dehydroquinate synthase — —
Acinetobacter radioresistens SK82 0.35 MPMX26_00544 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.50 MPMX26_02810 3-dehydroquinate synthase — —
Agrobacterium fabrum C58 0.34 Atu1354 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase 0.38 Atu3625 3-dehydroquinate synthase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF3439 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) 0.50 GFF1331 3-dehydroquinate synthase (EC 4.2.3.4) — —
Shewanella loihica PV-4 0.34 Shew_3132 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (RefSeq) 0.60 Shew_0214 3-dehydroquinate synthase (RefSeq) — —
Magnetospirillum magneticum AMB-1 0.33 AMB_RS11625 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.40 AMB_RS19865 3-dehydroquinate synthase — —
Synechococcus elongatus PCC 7942 0.32 Synpcc7942_2272 folK 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.40 Synpcc7942_0525 aroB 3-dehydroquinate synthase — —
Rhodopseudomonas palustris CGA009 0.30 TX73_009450 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.37 TX73_002610 3-dehydroquinate synthase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.30 ABZR88_RS13920 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.25 ABZR88_RS05215 3-dehydroquinate synthase — —
Azospirillum brasilense Sp245 0.29 AZOBR_RS14885 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 0.38 AZOBR_RS03220 3-dehydroquinate synthase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.28 CA264_10765 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.22 CA264_13105 3-dehydroquinate synthase — —
Dechlorosoma suillum PS 0.27 Dsui_1514 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.53 Dsui_1095 3-dehydroquinate synthase — —
Phaeobacter inhibens DSM 17395 0.27 PGA1_c00990 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK 0.38 PGA1_c14100 3-dehydroquinate synthase AroB — —
Ralstonia solanacearum PSI07 0.27 RPSI07_RS11995 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.50 RPSI07_RS10300 3-dehydroquinate synthase — —
Ralstonia solanacearum GMI1000 0.27 RS_RS13170 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.51 RS_RS14880 3-dehydroquinate synthase — —
Ralstonia solanacearum UW163 0.27 UW163_RS08320 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.50 UW163_RS06680 3-dehydroquinate synthase — —
Ralstonia solanacearum IBSBF1503 0.27 RALBFv3_RS05305 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.50 RALBFv3_RS06935 3-dehydroquinate synthase — —
Bacteroides stercoris CC31F 0.27 HMPREF1181_RS01700 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.21 HMPREF1181_RS09265 3-dehydroquinate synthase — —
Rhodospirillum rubrum S1H 0.24 Rru_A1858 7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (NCBI) 0.41 Rru_A3741 3-dehydroquinate synthase (NCBI) — —
Bacteroides ovatus ATCC 8483 0.22 BACOVA_02916 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase 0.21 BACOVA_04629 3-dehydroquinate synthase — —
Sphingomonas koreensis DSMZ 15582 0.19 Ga0059261_1977 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 0.36 Ga0059261_3591 3-dehydroquinate synthase (EC 4.2.3.4) — —
Dinoroseobacter shibae DFL-12 0.18 Dshi_0192 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (RefSeq) 0.36 Dshi_1608 3-dehydroquinate synthase (RefSeq) — —
Caulobacter crescentus NA1000 0.17 CCNA_01620 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.41 CCNA_03104 3-dehydroquinate synthase — —
Caulobacter crescentus NA1000 Δfur 0.17 CCNA_01620 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.41 CCNA_03104 3-dehydroquinate synthase — —

Not shown: 8 genomes with orthologs for b0142 only; 16 genomes with orthologs for b3389 only