| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Shewanella oneidensis MR-1 | SO2738 | bioC | biotin synthesis protein BioC (NCBI ptt file) | strong | 100 | 100 |
| o | Shewanella sp. ANA-3 | Shewana3_2517 | | biotin biosynthesis protein BioC (RefSeq) | no data | 84 | 100 |
| o | Shewanella loihica PV-4 | Shew_1721 | | methyltransferase type 11 (RefSeq) | no data | 48 | 92 |
| o | Shewanella amazonensis SB2B | Sama_1440 | | biotin synthesis protein BioC (RefSeq) | no data | 45 | 93 |
| o | Pseudomonas stutzeri RCH2 | Psest_0414 | | biotin biosynthesis protein BioC | strong | 35 | 92 |
| o | Pseudomonas sp. S08-1 | OH686_10340 | | malonyl-acyl carrier protein O-methyltransferase BioC | strong | 35 | 89 |
| o | Dickeya dianthicola 67-19 | HGI48_RS08685 | | malonyl-ACP O-methyltransferase BioC | insig. | 36 | 93 |
| o | Dickeya dadantii 3937 | DDA3937_RS08520 | | malonyl-ACP O-methyltransferase BioC | insig. | 35 | 93 |
| o | Pseudomonas sp. SVBP6 | COO64_RS22710 | bioC | malonyl-ACP O-methyltransferase BioC | strong | 35 | 82 |
| o | Dickeya dianthicola ME23 | DZA65_RS08975 | | malonyl-ACP O-methyltransferase BioC | insig. | 36 | 93 |
| o | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_4763 | | Biotin synthesis protein BioC | strong | 34 | 88 |
| o | Pseudomonas fluorescens SBW25 | PFLU_RS27635 | | malonyl-ACP O-methyltransferase BioC | strong | 33 | 82 |
| o | Pseudomonas fluorescens SBW25-INTG | PFLU_RS27635 | | malonyl-ACP O-methyltransferase BioC | strong | 33 | 82 |
| o | Pseudomonas fluorescens FW300-N2C3 | AO356_14150 | | malonyl-[acyl-carrier protein] O-methyltransferase BioC | strong | 33 | 88 |
| o | Pseudomonas fluorescens FW300-N2E3 | AO353_07510 | | malonyl-[acyl-carrier protein] O-methyltransferase BioC | strong | 33 | 82 |
| o | Pseudomonas segetis P6 | ACVTMO_RS03775 | bioC | malonyl-ACP O-methyltransferase BioC | strong | 33 | 84 |
| o | Pseudomonas simiae WCS417 | PS417_25990 | | malonyl-CoA O-methyltransferase | strong | 32 | 82 |
| o | Pseudomonas fluorescens GW456-L13 | PfGW456L13_1150 | | Biotin synthesis protein BioC | strong | 34 | 82 |
| o | Pseudomonas aeruginosa MRSN321 | DY961_RS22520 | bioC;go_function=malonyl-CoA | malonyl-ACP O-methyltransferase BioC | no data | 33 | 82 |
| o | Pseudomonas aeruginosa PUPa3 | DQ20_RS36810 | bioC;go_function=malonyl-CoA | malonyl-ACP O-methyltransferase BioC | insig. | 33 | 82 |
| o | Pseudomonas aeruginosa PA14 | IKLFDK_22920 | | malonyl-ACP O-methyltransferase BioC | strong | 33 | 82 |
| o | Vibrio cholerae E7946 ATCC 55056 | CSW01_05655 | | malonyl-[acyl-carrier protein] O-methyltransferase BioC | insig. | 33 | 88 |
| o | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_2490 | | Biotin synthesis protein BioC | strong | 30 | 82 |
| o | Pseudomonas sp. BP01 | JOY50_RS17945 | bioC | malonyl-ACP O-methyltransferase BioC | cofit | 31 | 87 |
| o | Rahnella sp. WP5 | EX31_RS23705 | | malonyl-ACP O-methyltransferase BioC | insig. | 34 | 71 |
| o | Pseudomonas lactucae CFBP13502 | GEMAOFIL_05319 | | Malonyl-[acyl-carrier protein] O-methyltransferase | insig. | 32 | 82 |
| o | Pseudomonas sp. RS175 | PFR28_04100 | | Malonyl-[acyl-carrier protein] O-methyltransferase | strong | 32 | 82 |
| o | Pseudomonas putida KT2440 | PP_0365 | | Malonyl-[acyl-carrier protein] O-methyltransferase | strong | 31 | 87 |
| o | Pseudomonas syringae pv. syringae B728a | Psyr_4684 | | biotin synthesis protein BioC | strong | 31 | 88 |
| o | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_4684 | | biotin synthesis protein BioC | strong | 31 | 88 |
| | Pantoea sp. MT58 | IAI47_13520 | | malonyl-ACP O-methyltransferase BioC | insig. | 36 | 71 |
| o | Pseudomonas sp. DMC3 | GFF73 | | Malonyl-[acyl-carrier protein] O-methyltransferase | insig. | 31 | 82 |
| | Klebsiella michiganensis M5al | BWI76_RS08770 | | malonyl-ACP O-methyltransferase BioC | sig. | 33 | 67 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS03780 | | malonyl-ACP O-methyltransferase BioC | cofit | 35 | 71 |
| o | Pseudomonas orientalis W4I3 | QF045_RS00400 | | malonyl-ACP O-methyltransferase BioC | insig. | 32 | 82 |
| o | Erwinia amylovora T8 | OLJFJH_16750 | | malonyl-ACP O-methyltransferase BioC | insig. | 33 | 85 |
| o | Methylophilus sp. DMC18 | GFF1685 | | Malonyl-[acyl-carrier protein] O-methyltransferase | cofit | 29 | 87 |
| | Escherichia coli ECRC100 | OKFHMN_06390 | bioC | malonyl-ACP O-methyltransferase BioC | insig. | 31 | 67 |
| | Escherichia coli ECRC101 | MCAODC_25605 | bioC | malonyl-ACP O-methyltransferase BioC | insig. | 31 | 67 |
| | Escherichia coli ECRC102 | NIAGMN_04435 | bioC | malonyl-ACP O-methyltransferase BioC | strong | 31 | 67 |
| | Escherichia coli ECRC98 | JDDGAC_10025 | bioC | malonyl-ACP O-methyltransferase BioC | insig. | 31 | 67 |
| | Escherichia coli ECRC99 | KEDOAH_21520 | bioC | malonyl-ACP O-methyltransferase BioC | no data | 31 | 67 |
| | Escherichia fergusonii Becca | EFB2_03328 | | Malonyl-[acyl-carrier protein] O-methyltransferase | insig. | 31 | 67 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS04140 | | malonyl-ACP O-methyltransferase BioC | insig. | 31 | 67 |
| o | Pectobacterium carotovorum WPP14 | HER17_RS13450 | | malonyl-ACP O-methyltransferase BioC | cofit | 32 | 88 |
| | Escherichia coli ECOR38 | HEPCGN_01650 | bioC | malonyl-ACP O-methyltransferase BioC | insig. | 31 | 67 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_19575 | bioC | malonyl-ACP O-methyltransferase BioC | no data | 34 | 71 |
| | Erwinia tracheiphila SCR3 | LU632_RS09140 | bioC | malonyl-ACP O-methyltransferase BioC | no data | 34 | 71 |
| | Alteromonas macleodii MIT1002 | MIT1002_01381 | | Malonyl-CoA O-methyltransferase BioC | strong | 28 | 92 |
| o | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF673 | | Biotin synthesis protein BioC | insig. | 33 | 67 |
| | Escherichia coli ECOR27 | NOLOHH_22760 | bioC | malonyl-ACP O-methyltransferase BioC | insig. | 31 | 67 |
| | Escherichia coli BL21 | ECD_00744 | | malonyl-ACP O-methyltransferase, SAM-dependent | insig. | 31 | 67 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02936 | | Malonyl-[acyl-carrier protein] O-methyltransferase | insig. | 31 | 67 |
| | Escherichia coli BW25113 | b0777 | bioC | predicted methltransferase, enzyme of biotin synthesis (NCBI) | sig. | 31 | 67 |
| | Escherichia coli ECRC62 | BNILDI_21030 | bioC | malonyl-ACP O-methyltransferase BioC | cofit | 31 | 67 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_13670 | bioC | malonyl-ACP O-methyltransferase BioC | no data | 32 | 69 |
| | Serratia liquefaciens MT49 | IAI46_06535 | | malonyl-ACP O-methyltransferase BioC | insig. | 33 | 71 |
| o | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS03020 | | malonyl-ACP O-methyltransferase BioC | no data | 27 | 89 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS09880 | | malonyl-ACP O-methyltransferase BioC | no data | 31 | 69 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS10240 | | malonyl-ACP O-methyltransferase BioC | no data | 31 | 69 |
| o | Klebsiella pneumoniae MKP103 | KDGMDA_17035 | | malonyl-ACP O-methyltransferase BioC | sig. | 30 | 84 |
| | Marinobacter adhaerens HP15 | HP15_2483 | | protein containing methyltransferase type 11 domain | insig. | 32 | 57 |
| o | Dechlorosoma suillum PS | Dsui_2883 | | biotin biosynthesis protein BioC | strong | 28 | 90 |
| | Enterobacter sp. TBS_079 | MPMX20_01405 | | Malonyl-[acyl-carrier protein] O-methyltransferase | sig. | 30 | 68 |
| o | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS15820 | | malonyl-ACP O-methyltransferase BioC | no data | 28 | 87 |
| o | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.498.1 | | Biotin synthesis protein BioC | no data | 30 | 82 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_2214 | | malonyl-acyl carrier protein O-methyltransferase BioC | insig. | 28 | 67 |
| o | Kangiella aquimarina DSM 16071 | B158DRAFT_0867 | | biotin biosynthesis protein BioC | no data | 26 | 88 |
| o | Lysobacter sp. OAE881 | ABIE51_RS01160 | | malonyl-ACP O-methyltransferase BioC | no data | 25 | 87 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS01865 | | amidophosphoribosyltransferase | no data | 27 | 77 |
| | Acinetobacter radioresistens SK82 | MPMX26_02452 | | Malonyl-[acyl-carrier protein] O-methyltransferase | strong | 26 | 72 |
| | Sphingobium sp. HT1-2 | GFF2407 | | Malonyl-[acyl-carrier protein] O-methyltransferase (EC 2.1.1.197) | cofit | 30 | 72 |
| | Methanococcus maripaludis S2 | MMP_RS07855 | | class I SAM-dependent methyltransferase | insig. | 34 | 38 |
| | Klebsiella michiganensis M5al | BWI76_RS01305 | | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase | no data | 33 | 50 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_09795 | | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1 4-benzoquinol methylase UbiE | no data | 33 | 50 |
| | Mycobacterium tuberculosis H37Rv | Rv3342 | | Possible methyltransferase (methylase) | sig. | 35 | 34 |
| | Escherichia coli BL21 | ECD_03726 | | bifunctional 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase/ S-adenosylmethionine:2-DMK methyltransferase | no data | 33 | 50 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_4498 | | ubiquinone/menaquinone biosynthesis methyltransferases | no data | 33 | 50 |
| | Enterobacter sp. TBS_079 | MPMX20_04447 | | Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE | no data | 33 | 50 |
| | Escherichia fergusonii Becca | EFB2_04782 | | Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE | no data | 33 | 50 |
| | Escherichia coli ECOR27 | NOLOHH_06435 | ubiE | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE | no data | 33 | 50 |
| | Escherichia coli ECOR38 | HEPCGN_12935 | ubiE | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE | strong | 33 | 50 |
| | Escherichia coli ECRC100 | OKFHMN_14305 | ubiE | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE | no data | 33 | 50 |
| | Escherichia coli ECRC101 | MCAODC_04810 | ubiE | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE | no data | 33 | 50 |
| | Escherichia coli ECRC102 | NIAGMN_12060 | ubiE | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE | no data | 33 | 50 |
| | Escherichia coli ECRC62 | BNILDI_05095 | ubiE | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE | no data | 33 | 50 |
| | Escherichia coli ECRC98 | JDDGAC_17930 | ubiE | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE | no data | 33 | 50 |
| | Escherichia coli ECRC99 | KEDOAH_13845 | ubiE | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE | no data | 33 | 50 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_04218 | | Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE | no data | 33 | 50 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS22115 | | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE | no data | 33 | 50 |
| | Escherichia coli BW25113 | b3833 | ubiE | ubiquinone/menaquinone biosynthesis methyltransferase (NCBI) | no data | 33 | 50 |
| | Variovorax sp. OAS795 | ABID97_RS16745 | | class I SAM-dependent methyltransferase | cofit | 36 | 37 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS32430 | | SAM-dependent methyltransferase | insig. | 34 | 34 |
| | Methanococcus maripaludis JJ | MMJJ_RS06500 | | class I SAM-dependent methyltransferase | insig. | 33 | 38 |
| | Rhodopseudomonas palustris CGA009 | TX73_018460 | | arsenite methyltransferase | insig. | 29 | 57 |
| o | Acinetobacter baumannii LAC-4 | RR41_RS15225 | | malonyl-ACP O-methyltransferase BioC | no data | 25 | 91 |
| | Serratia liquefaciens MT49 | IAI46_00185 | | class I SAM-dependent methyltransferase | insig. | 31 | 36 |
| | Azospirillum sp. SherDot2 | MPMX19_03826 | | putative methyltransferase | no data | 30 | 47 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS15820 | | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE | no data | 27 | 59 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF260 | | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE (EC 2.1.1.-) @ 2-heptaprenyl-1,4-naphthoquinone methyltransferase (EC 2.1.1.163) | no data | 32 | 50 |