Conservation of cofitness between QEN71_RS12390 and QEN71_RS12865 in Paraburkholderia sabiae LMG 24235

52 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Paraburkholderia sabiae LMG 24235 1.0 QEN71_RS12390 3-hydroxyisobutyrate dehydrogenase 1.0 QEN71_RS12865 carboxyl transferase domain-containing protein 0.68 6
Burkholderia phytofirmans PsJN 0.78 BPHYT_RS28025 3-hydroxyisobutyrate dehydrogenase 0.95 BPHYT_RS23265 methylcrotonoyl-CoA carboxylase low > 109
Ralstonia sp. UNC404CL21Col 0.77 ABZR87_RS17475 3-hydroxyisobutyrate dehydrogenase 0.86 ABZR87_RS06280 carboxyl transferase domain-containing protein low > 80
Paraburkholderia bryophila 376MFSha3.1 0.77 H281DRAFT_01201 3-hydroxyisobutyrate dehydrogenase 0.94 H281DRAFT_01345 3-methylcrotonyl-CoA carboxylase beta subunit 0.51 7
Paraburkholderia graminis OAS925 0.76 ABIE53_005735 3-hydroxyisobutyrate dehydrogenase 0.94 ABIE53_005466 3-methylcrotonyl-CoA carboxylase beta subunit low > 113
Ralstonia solanacearum PSI07 0.74 RPSI07_RS02325 3-hydroxyisobutyrate dehydrogenase 0.85 RPSI07_RS22835 methylcrotonoyl-CoA carboxylase low > 81
Ralstonia solanacearum UW163 0.73 UW163_RS18760 3-hydroxyisobutyrate dehydrogenase 0.85 UW163_RS03100 methylcrotonoyl-CoA carboxylase — —
Ralstonia solanacearum IBSBF1503 0.73 RALBFv3_RS20415 3-hydroxyisobutyrate dehydrogenase 0.85 RALBFv3_RS10480 methylcrotonoyl-CoA carboxylase low > 76
Ralstonia solanacearum GMI1000 0.70 RS_RS20225 3-hydroxyisobutyrate dehydrogenase 0.85 RS_RS01320 methylcrotonoyl-CoA carboxylase low > 80
Cupriavidus basilensis FW507-4G11 0.65 RR42_RS28555 3-hydroxyisobutyrate dehydrogenase 0.87 RR42_RS26905 methylcrotonoyl-CoA carboxylase — —
Pseudomonas simiae WCS417 0.64 PS417_23720 3-hydroxyisobutyrate dehydrogenase 0.73 PS417_17020 methylcrotonoyl-CoA carboxylase — —
Pseudomonas fluorescens SBW25-INTG 0.64 PFLU_RS25535 3-hydroxyisobutyrate dehydrogenase 0.73 PFLU_RS18970 methylcrotonoyl-CoA carboxylase 0.25 30
Pseudomonas fluorescens SBW25 0.64 PFLU_RS25535 3-hydroxyisobutyrate dehydrogenase 0.73 PFLU_RS18970 methylcrotonoyl-CoA carboxylase low > 109
Pseudomonas fluorescens FW300-N2C3 0.63 AO356_07865 3-hydroxyisobutyrate dehydrogenase 0.72 AO356_01585 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) 0.25 101
Pseudomonas sp. RS175 0.63 PFR28_00014 3-hydroxyisobutyrate dehydrogenase 0.72 PFR28_01259 Methylmalonyl-CoA carboxyltransferase 12S subunit 0.44 23
Pseudomonas fluorescens FW300-N2E2 0.63 Pf6N2E2_3451 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) 0.72 Pf6N2E2_2192 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) 0.27 16
Pseudomonas syringae pv. syringae B728a 0.62 Psyr_0690 3-hydroxyisobutyrate dehydrogenase 0.71 Psyr_2469 Propionyl-CoA carboxylase low > 86
Pseudomonas putida KT2440 0.62 PP_4666 3-hydroxyisobutyrate dehydrogenase 0.72 PP_4065 methylcrotonyl-CoA carboxylase biotin-containing subunit beta 0.20 31
Pseudomonas syringae pv. syringae B728a ΔmexB 0.62 Psyr_0690 3-hydroxyisobutyrate dehydrogenase 0.71 Psyr_2469 Propionyl-CoA carboxylase low > 86
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_5145 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data) 0.73 PfGW456L13_2590 Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) 0.67 15
Pseudomonas fluorescens FW300-N1B4 0.61 Pf1N1B4_1228 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) 0.73 Pf1N1B4_3986 Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) 0.24 25
Pseudomonas fluorescens FW300-N2E3 0.61 AO353_05985 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data) 0.72 AO353_20345 methylcrotonoyl-CoA carboxylase 0.31 36
Pseudomonas stutzeri RCH2 0.61 Psest_2438 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data) 0.72 Psest_1083 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) 0.41 4
Acinetobacter radioresistens SK82 0.56 MPMX26_01549 3-hydroxyisobutyrate dehydrogenase 0.78 MPMX26_00631 Propionyl-CoA carboxylase beta chain — —
Marinobacter adhaerens HP15 0.51 HP15_910 3-hydroxyisobutyrate dehydrogenase 0.74 HP15_1004 3-methylcrotonyl CoA carboxylase, beta subunit low > 73
Xanthomonas campestris pv. campestris strain 8004 0.49 Xcc-8004.3685.1 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) 0.77 Xcc-8004.319.1 Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) 0.34 54
Castellaniella sp019104865 MT123 0.48 ABCV34_RS03985 3-hydroxyisobutyrate dehydrogenase 0.76 ABCV34_RS12355 carboxyl transferase domain-containing protein 0.87 5
Herbaspirillum seropedicae SmR1 0.48 HSERO_RS15390 3-hydroxyisobutyrate dehydrogenase 0.84 HSERO_RS23455 methylcrotonoyl-CoA carboxylase low > 78
Acidovorax sp. GW101-3H11 0.48 Ac3H11_2362 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) 0.82 Ac3H11_3010 Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) — —
Shewanella oneidensis MR-1 0.48 SO1682 mmsB 3-hydroxyisobutyrate dehydrogenase (NCBI ptt file) 0.76 SO1896 pccB-1 3-methylcrotonyl CoA carboxylase, beta subunit (NCBI ptt file) low > 76
Magnetospirillum magneticum AMB-1 0.46 AMB_RS18155 3-hydroxyisobutyrate dehydrogenase 0.77 AMB_RS03475 methylcrotonoyl-CoA carboxylase low > 64
Variovorax sp. SCN45 0.46 GFF7381 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) 0.80 GFF2008 Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) 0.88 79
Variovorax sp. OAS795 0.45 ABID97_RS19405 3-hydroxyisobutyrate dehydrogenase 0.79 ABID97_RS25130 carboxyl transferase domain-containing protein 0.34 48
Shewanella amazonensis SB2B 0.45 Sama_1380 3-hydroxyisobutyrate dehydrogenase (RefSeq) 0.76 Sama_1361 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) low > 62
Azospirillum brasilense Sp245 0.45 AZOBR_RS22360 3-hydroxyisobutyrate dehydrogenase 0.80 AZOBR_RS22295 methylcrotonoyl-CoA carboxylase low > 97
Shewanella sp. ANA-3 0.44 Shewana3_2766 3-hydroxyisobutyrate dehydrogenase (RefSeq) 0.76 Shewana3_1671 carboxyl transferase (RefSeq) low > 73
Brevundimonas sp. GW460-12-10-14-LB2 0.43 A4249_RS03595 3-hydroxyisobutyrate dehydrogenase 0.71 A4249_RS03795 carboxyl transferase domain-containing protein low > 48
Shewanella loihica PV-4 0.42 Shew_1672 3-hydroxyisobutyrate dehydrogenase (RefSeq) 0.76 Shew_2571 propionyl-CoA carboxylase (RefSeq) low > 60
Rhizobium sp. OAE497 0.42 ABIE40_RS24830 3-hydroxyisobutyrate dehydrogenase 0.75 ABIE40_RS20780 carboxyl transferase domain-containing protein low > 107
Agrobacterium fabrum C58 0.42 Atu4129 3-hydroxyisobutyrate dehydrogenase 0.77 Atu3478 3-methylcrotonoyl-CoA carboxylase beta subunit low > 89
Pseudomonas sp. S08-1 0.41 OH686_05885 3-hydroxyisobutyrate dehydrogenase 0.71 OH686_00850 Methylcrotonyl-CoA carboxylase carboxyl transferase subunit low > 80
Azospirillum sp. SherDot2 0.40 MPMX19_05421 putative 3-hydroxyisobutyrate dehydrogenase 0.78 MPMX19_03938 Methylmalonyl-CoA carboxyltransferase 12S subunit low > 112
Bosea sp. OAE506 0.40 ABIE41_RS23930 3-hydroxyisobutyrate dehydrogenase 0.72 ABIE41_RS14815 carboxyl transferase domain-containing protein 0.36 8
Sinorhizobium meliloti 1021 0.40 SM_b20751 3-hydroxyisobutyrate dehydrogenase 0.74 SM_b21122 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) low > 103
Sphingomonas koreensis DSMZ 15582 0.39 Ga0059261_3686 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) 0.74 Ga0059261_4055 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) low > 68
Rhodopseudomonas palustris CGA009 0.37 TX73_017835 3-hydroxyisobutyrate dehydrogenase 0.74 TX73_013115 carboxyl transferase domain-containing protein low > 86
Caulobacter crescentus NA1000 Δfur 0.36 CCNA_01416 3-hydroxyisobutyrate dehydrogenase 0.72 CCNA_02252 methylcrotonyl-CoA carboxylase carboxyl transferase subunit low > 67
Caulobacter crescentus NA1000 0.36 CCNA_01416 3-hydroxyisobutyrate dehydrogenase 0.72 CCNA_02252 methylcrotonyl-CoA carboxylase carboxyl transferase subunit low > 66
Rhodospirillum rubrum S1H 0.36 Rru_A1833 3-hydroxyisobutyrate dehydrogenase (NCBI) 0.73 Rru_A1943 Propionyl-CoA carboxylase (NCBI) low > 58
Alteromonas macleodii MIT1002 0.36 MIT1002_03327 3-hydroxyisobutyrate dehydrogenase 0.75 MIT1002_01668 Methylmalonyl-CoA carboxyltransferase 12S subunit low > 70
Phaeobacter inhibens DSM 17395 0.34 PGA1_c17360 3-hydroxyisobutyrate dehydrogenase MmsB 0.71 PGA1_c10320 methylcrotonoyl-CoA carboxylase beta chain — —
Mycobacterium tuberculosis H37Rv 0.34 Rv0751c Probable 3-hydroxyisobutyrate dehydrogenase MmsB (hibadh) 0.68 Rv2502c Probable acetyl-/propionyl-CoA carboxylase (beta subunit) AccD1 low > 58
Dinoroseobacter shibae DFL-12 0.34 Dshi_1752 3-hydroxyisobutyrate dehydrogenase (RefSeq) 0.69 Dshi_1300 Propionyl-CoA carboxylase (RefSeq) low > 64

Not shown: 1 genomes with orthologs for QEN71_RS12390 only; 20 genomes with orthologs for QEN71_RS12865 only