Conservation of cofitness between PP_4922 and PP_2327 in Pseudomonas putida KT2440

68 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_4922 Phosphomethylpyrimidine synthase 1.0 PP_2327 transcriptional dual regulator / CysB-O-acetyl-L-serine 0.48 20
Pseudomonas sp. RS175 0.92 PFR28_05091 Phosphomethylpyrimidine synthase 0.96 PFR28_00966 HTH-type transcriptional regulator CysB low > 88
Pseudomonas fluorescens FW300-N2C3 0.92 AO356_08810 thiamine biosynthesis protein ThiC 0.97 AO356_03180 CysB family transcriptional regulator low > 104
Pseudomonas fluorescens FW300-N2E2 0.92 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.97 Pf6N2E2_2465 Cys regulon transcriptional activator CysB low > 103
Pseudomonas syringae pv. syringae B728a 0.92 Psyr_0544 hydroxymethylpyrimidine synthase 0.93 Psyr_2077 regulatory protein, LysR:LysR, substrate-binding protein 0.71 8
Pseudomonas fluorescens SBW25-INTG 0.92 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.96 PFLU_RS08410 HTH-type transcriptional regulator CysB 0.38 22
Pseudomonas fluorescens SBW25 0.92 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.96 PFLU_RS08410 HTH-type transcriptional regulator CysB low > 109
Pseudomonas syringae pv. syringae B728a ΔmexB 0.92 Psyr_0544 hydroxymethylpyrimidine synthase 0.93 Psyr_2077 regulatory protein, LysR:LysR, substrate-binding protein low > 86
Pseudomonas fluorescens GW456-L13 0.92 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.97 PfGW456L13_2230 Cys regulon transcriptional activator CysB low > 87
Pseudomonas fluorescens FW300-N2E3 0.92 AO353_13010 thiamine biosynthesis protein ThiC 0.97 AO353_19060 CysB family transcriptional regulator low > 101
Pseudomonas simiae WCS417 0.91 PS417_02355 thiamine biosynthesis protein ThiC 0.96 PS417_08460 CysB family transcriptional regulator — —
Pseudomonas fluorescens FW300-N1B4 0.91 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.96 Pf1N1B4_283 Cys regulon transcriptional activator CysB — —
Pseudomonas sp. S08-1 0.91 OH686_15885 phosphomethylpyrimidine synthase 0.93 OH686_01730 Cys regulon transcriptional activator CysB low > 80
Pseudomonas stutzeri RCH2 0.90 Psest_0477 thiamine biosynthesis protein ThiC 0.91 Psest_2329 Transcriptional regulator low > 67
Marinobacter adhaerens HP15 0.83 HP15_453 thiamine biosynthesis protein thiC 0.80 HP15_1854 transcriptional regulator, LysR family — —
Paraburkholderia sabiae LMG 24235 0.78 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.48 QEN71_RS22570 CysB family HTH-type transcriptional regulator low > 153
Herbaspirillum seropedicae SmR1 0.78 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC 0.47 HSERO_RS08245 CysB family transcriptional regulator low > 78
Dechlorosoma suillum PS 0.77 Dsui_0422 thiamine biosynthesis protein ThiC 0.52 Dsui_1988 transcriptional regulator — —
Dyella japonica UNC79MFTsu3.2 0.77 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC 0.37 ABZR86_RS05885 LysR substrate-binding domain-containing protein low > 74
Acinetobacter radioresistens SK82 0.77 MPMX26_00180 Phosphomethylpyrimidine synthase 0.40 MPMX26_02171 HTH-type transcriptional regulator SsuR low > 36
Paraburkholderia graminis OAS925 0.77 ABIE53_002857 phosphomethylpyrimidine synthase 0.49 ABIE53_001994 LysR family cys regulon transcriptional activator low > 113
Paraburkholderia bryophila 376MFSha3.1 0.77 H281DRAFT_00395 hydroxymethylpyrimidine synthase 0.49 H281DRAFT_00782 transcriptional regulator, LysR family low > 103
Burkholderia phytofirmans PsJN 0.77 BPHYT_RS13220 phosphomethylpyrimidine synthase 0.49 BPHYT_RS08810 CysB family transcriptional regulator low > 109
Rhodanobacter sp. FW510-T8 0.76 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC 0.37 OKGIIK_05975 lysR CysB family transcriptional regulator low > 52
Castellaniella sp019104865 MT123 0.75 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC 0.37 ABCV34_RS08230 CysB family HTH-type transcriptional regulator low > 48
Lysobacter sp. OAE881 0.75 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC 0.34 ABIE51_RS15850 LysR family transcriptional regulator low > 62
Pectobacterium carotovorum WPP14 0.74 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.68 HER17_RS10870 HTH-type transcriptional regulator CysB 0.79 44
Xanthomonas campestris pv. campestris strain 8004 0.74 Xcc-8004.1066.1 hypothetical protein 0.30 Xcc-8004.1249.1 Transcriptional regulator low > 74
Ralstonia sp. UNC404CL21Col 0.74 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC 0.47 ABZR87_RS11555 CysB family HTH-type transcriptional regulator low > 80
Ralstonia solanacearum PSI07 0.74 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC 0.46 RPSI07_RS17385 CysB family HTH-type transcriptional regulator low > 81
Ralstonia solanacearum IBSBF1503 0.74 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC 0.46 RALBFv3_RS00100 CysB family HTH-type transcriptional regulator low > 76
Ralstonia solanacearum UW163 0.74 UW163_RS03640 phosphomethylpyrimidine synthase ThiC 0.46 UW163_RS13430 CysB family HTH-type transcriptional regulator — —
Ralstonia solanacearum GMI1000 0.74 RS_RS00555 phosphomethylpyrimidine synthase 0.46 RS_RS06760 CysB family HTH-type transcriptional regulator low > 80
Shewanella loihica PV-4 0.74 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.66 Shew_1624 cysB transcriptional regulator CysB (RefSeq) — —
Pantoea sp. MT58 0.73 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.67 IAI47_09240 HTH-type transcriptional regulator CysB low > 76
Dickeya dadantii 3937 0.73 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.68 DDA3937_RS10540 HTH-type transcriptional regulator CysB low > 74
Rahnella sp. WP5 0.73 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.68 EX31_RS09890 HTH-type transcriptional regulator CysB low > 89
Cupriavidus basilensis FW507-4G11 0.73 RR42_RS01290 thiamine biosynthesis protein ThiC 0.45 RR42_RS12245 transcriptional regulator low > 128
Serratia liquefaciens MT49 0.73 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.68 IAI46_13965 HTH-type transcriptional regulator CysB — —
Escherichia coli ECOR27 0.72 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.67 NOLOHH_20265 cysB HTH-type transcriptional regulator CysB — —
Escherichia coli Nissle 1917 0.72 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.67 ECOLIN_RS07680 HTH-type transcriptional regulator CysB low > 52
Escherichia coli HS(pFamp)R (ATCC 700891) 0.72 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 0.67 OHPLBJKB_02409 HTH-type transcriptional regulator CysB low > 73
Escherichia coli ECRC62 0.72 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.67 BNILDI_18415 cysB HTH-type transcriptional regulator CysB — —
Escherichia fergusonii Becca 0.72 EFB2_04617 Phosphomethylpyrimidine synthase 0.67 EFB2_02652 HTH-type transcriptional regulator CysB — —
Escherichia coli BW25113 0.72 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.67 b1275 cysB DNA-binding transcriptional dual regulator, O-acetyl-L-serine-binding (NCBI) — —
Escherichia coli ECRC98 0.72 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 0.67 JDDGAC_05145 cysB HTH-type transcriptional regulator CysB — —
Escherichia coli ECRC102 0.72 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 0.67 NIAGMN_26770 cysB HTH-type transcriptional regulator CysB — —
Dickeya dianthicola 67-19 0.72 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.69 HGI48_RS10540 HTH-type transcriptional regulator CysB low > 71
Erwinia tracheiphila SCR3 0.72 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC 0.67 LU632_RS12550 cysB HTH-type transcriptional regulator CysB — —
Escherichia coli ECRC99 0.72 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 0.67 KEDOAH_26165 cysB HTH-type transcriptional regulator CysB — —
Escherichia coli ECRC101 0.72 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.67 OKFHMN_02600 cysB HTH-type transcriptional regulator CysB — —
Shewanella amazonensis SB2B 0.72 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.66 Sama_1324 cysB transcriptional regulator CysB (RefSeq) — —
Escherichia coli ECRC101 0.72 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.67 MCAODC_15665 cysB HTH-type transcriptional regulator CysB — —
Kangiella aquimarina DSM 16071 0.72 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.43 B158DRAFT_2455 Transcriptional regulator low > 40
Dickeya dianthicola ME23 0.72 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.68 DZA65_RS11020 HTH-type transcriptional regulator CysB 0.68 51
Enterobacter sp. TBS_079 0.72 MPMX20_00217 Phosphomethylpyrimidine synthase 0.67 MPMX20_02501 HTH-type transcriptional regulator CysB — —
Escherichia coli ECOR38 0.72 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.67 HEPCGN_25600 cysB HTH-type transcriptional regulator CysB — —
Escherichia coli BL21 0.72 ECD_03871 phosphomethylpyrimidine synthase 0.67 ECD_01251 N-acetylserine-responsive cysteine regulon transcriptional activator; autorepressor — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.72 GFF4198 Thiamin biosynthesis protein ThiC 0.68 GFF2712 Cys regulon transcriptional activator CysB — —
Enterobacter asburiae PDN3 0.72 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.67 EX28DRAFT_0946 Transcriptional regulator — —
Klebsiella michiganensis M5al 0.71 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.67 BWI76_RS11930 LysR family transcriptional regulator CysB — —
Alteromonas macleodii MIT1002 0.71 MIT1002_00097 Phosphomethylpyrimidine synthase 0.68 MIT1002_02005 Cys regulon transcriptional activator — —
Shewanella oneidensis MR-1 0.71 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.66 SO2649 cysB cys regulon transcriptional activator (NCBI ptt file) low > 76
Vibrio cholerae E7946 ATCC 55056 0.71 CSW01_00335 phosphomethylpyrimidine synthase 0.70 CSW01_09545 HTH-type transcriptional regulator CysB — —
Shewanella sp. ANA-3 0.70 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.65 Shewana3_1731 cysB transcriptional regulator CysB (RefSeq) — —
Variovorax sp. SCN45 0.69 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.47 GFF3358 Alkanesulfonate utilization operon LysR-family regulator Cbl low > 127
Variovorax sp. OAS795 0.68 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.46 ABID97_RS02980 CysB family HTH-type transcriptional regulator low > 91
Hydrogenophaga sp. GW460-11-11-14-LB1 0.68 GFF4626 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.48 GFF5044 Alkanesulfonate utilization operon LysR-family regulator CbI low > 90
Acidovorax sp. GW101-3H11 0.67 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.44 Ac3H11_2403 Alkanesulfonate utilization operon LysR-family regulator CbI 0.65 59

Not shown: 25 genomes with orthologs for PP_4922 only; 2 genomes with orthologs for PP_2327 only