Conservation of cofitness between PP_0586 and PP_2327 in Pseudomonas putida KT2440

65 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_0586 cadmium translocating P-type ATPase 1.0 PP_2327 transcriptional dual regulator / CysB-O-acetyl-L-serine 0.20 20
Pseudomonas fluorescens GW456-L13 0.79 PfGW456L13_24 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.97 PfGW456L13_2230 Cys regulon transcriptional activator CysB low > 87
Pseudomonas fluorescens FW300-N2E3 0.79 AO353_06155 copper-transporting ATPase 0.97 AO353_19060 CysB family transcriptional regulator 0.45 16
Pseudomonas fluorescens FW300-N2E2 0.79 Pf6N2E2_3487 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.97 Pf6N2E2_2465 Cys regulon transcriptional activator CysB low > 103
Pseudomonas fluorescens FW300-N2C3 0.79 AO356_08065 copper-transporting ATPase 0.97 AO356_03180 CysB family transcriptional regulator low > 104
Pseudomonas sp. RS175 0.78 PFR28_05244 Copper-exporting P-type ATPase 0.96 PFR28_00966 HTH-type transcriptional regulator CysB low > 88
Pseudomonas fluorescens FW300-N1B4 0.77 Pf1N1B4_1262 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.96 Pf1N1B4_283 Cys regulon transcriptional activator CysB
Pseudomonas simiae WCS417 0.72 PS417_03160 metal ABC transporter ATPase 0.96 PS417_08460 CysB family transcriptional regulator
Pseudomonas stutzeri RCH2 0.72 Psest_0738 copper-(or silver)-translocating P-type ATPase 0.91 Psest_2329 Transcriptional regulator low > 67
Pseudomonas fluorescens SBW25 0.72 PFLU_RS03240 copper-translocating P-type ATPase 0.96 PFLU_RS08410 HTH-type transcriptional regulator CysB low > 109
Pseudomonas fluorescens SBW25-INTG 0.72 PFLU_RS03240 copper-translocating P-type ATPase 0.96 PFLU_RS08410 HTH-type transcriptional regulator CysB low > 109
Pseudomonas sp. S08-1 0.68 OH686_07395 copper-translocating P-type ATPase 0.93 OH686_01730 Cys regulon transcriptional activator CysB low > 80
Pseudomonas syringae pv. syringae B728a ΔmexB 0.68 Psyr_0654 Copper-translocating P-type ATPase:Heavy metal translocating P-type ATPase 0.93 Psyr_2077 regulatory protein, LysR:LysR, substrate-binding protein low > 86
Pseudomonas syringae pv. syringae B728a 0.68 Psyr_0654 Copper-translocating P-type ATPase:Heavy metal translocating P-type ATPase 0.93 Psyr_2077 regulatory protein, LysR:LysR, substrate-binding protein 0.41 13
Paraburkholderia sabiae LMG 24235 0.55 QEN71_RS17330 heavy metal translocating P-type ATPase 0.48 QEN71_RS22570 CysB family HTH-type transcriptional regulator low > 153
Acidovorax sp. GW101-3H11 0.55 Ac3H11_4218 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.44 Ac3H11_2403 Alkanesulfonate utilization operon LysR-family regulator CbI low > 79
Burkholderia phytofirmans PsJN 0.54 BPHYT_RS34125 heavy metal translocating P-type ATPase 0.49 BPHYT_RS08810 CysB family transcriptional regulator low > 109
Lysobacter sp. OAE881 0.53 ABIE51_RS09555 heavy metal translocating P-type ATPase 0.34 ABIE51_RS15850 LysR family transcriptional regulator low > 62
Paraburkholderia bryophila 376MFSha3.1 0.51 H281DRAFT_03512 Cu+-exporting ATPase 0.49 H281DRAFT_00782 transcriptional regulator, LysR family low > 103
Ralstonia sp. UNC404CL21Col 0.51 ABZR87_RS04235 heavy metal translocating P-type ATPase 0.47 ABZR87_RS11555 CysB family HTH-type transcriptional regulator low > 80
Cupriavidus basilensis FW507-4G11 0.50 RR42_RS20305 metal ABC transporter ATPase 0.45 RR42_RS12245 transcriptional regulator low > 128
Paraburkholderia graminis OAS925 0.50 ABIE53_004745 Cu+-exporting ATPase 0.49 ABIE53_001994 LysR family cys regulon transcriptional activator low > 113
Ralstonia solanacearum IBSBF1503 0.50 RALBFv3_RS08960 copper-translocating P-type ATPase 0.46 RALBFv3_RS00100 CysB family HTH-type transcriptional regulator low > 76
Ralstonia solanacearum UW163 0.50 UW163_RS04650 copper-translocating P-type ATPase 0.46 UW163_RS13430 CysB family HTH-type transcriptional regulator
Ralstonia solanacearum GMI1000 0.50 RS_RS16775 copper-translocating P-type ATPase 0.46 RS_RS06760 CysB family HTH-type transcriptional regulator low > 80
Ralstonia solanacearum PSI07 0.49 RPSI07_RS08310 copper-translocating P-type ATPase 0.46 RPSI07_RS17385 CysB family HTH-type transcriptional regulator low > 81
Herbaspirillum seropedicae SmR1 0.49 HSERO_RS08020 heavy metal translocating P-type ATPase 0.47 HSERO_RS08245 CysB family transcriptional regulator low > 78
Dechlorosoma suillum PS 0.49 Dsui_1065 copper/silver-translocating P-type ATPase 0.52 Dsui_1988 transcriptional regulator
Rhodanobacter denitrificans MT42 0.49 LRK55_RS18700 heavy metal translocating P-type ATPase 0.35 LRK55_RS00690 LysR substrate-binding domain-containing protein low > 63
Hydrogenophaga sp. GW460-11-11-14-LB1 0.46 GFF2052 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.48 GFF5044 Alkanesulfonate utilization operon LysR-family regulator CbI low > 90
Shewanella amazonensis SB2B 0.46 Sama_1786 copper-translocating P-type ATPase (RefSeq) 0.66 Sama_1324 cysB transcriptional regulator CysB (RefSeq)
Variovorax sp. SCN45 0.45 GFF3317 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.47 GFF3358 Alkanesulfonate utilization operon LysR-family regulator Cbl low > 127
Variovorax sp. OAS795 0.44 ABID97_RS02825 heavy metal translocating P-type ATPase 0.46 ABID97_RS02980 CysB family HTH-type transcriptional regulator low > 91
Acinetobacter radioresistens SK82 0.38 MPMX26_01948 Copper-transporting P-type ATPase 0.40 MPMX26_02171 HTH-type transcriptional regulator SsuR low > 36
Serratia liquefaciens MT49 0.37 IAI46_13395 copper-translocating P-type ATPase 0.68 IAI46_13965 HTH-type transcriptional regulator CysB
Klebsiella michiganensis M5al 0.34 BWI76_RS06905 Cu+ exporting ATPase 0.67 BWI76_RS11930 LysR family transcriptional regulator CysB
Marinobacter adhaerens HP15 0.34 HP15_3546 copper-translocating P-type ATPase 0.80 HP15_1854 transcriptional regulator, LysR family
Kangiella aquimarina DSM 16071 0.33 B158DRAFT_1616 copper-(or silver)-translocating P-type ATPase 0.43 B158DRAFT_2455 Transcriptional regulator low > 40
Enterobacter asburiae PDN3 0.33 EX28DRAFT_2474 copper-(or silver)-translocating P-type ATPase 0.67 EX28DRAFT_0946 Transcriptional regulator
Enterobacter sp. TBS_079 0.33 MPMX20_01084 Copper-exporting P-type ATPase 0.67 MPMX20_02501 HTH-type transcriptional regulator CysB
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.33 GFF4404 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.68 GFF2712 Cys regulon transcriptional activator CysB
Escherichia coli ECOR38 0.32 HEPCGN_06710 copA copper-exporting P-type ATPase CopA 0.67 HEPCGN_25600 cysB HTH-type transcriptional regulator CysB low > 87
Escherichia coli BL21 0.32 ECD_00435 copper transporter 0.67 ECD_01251 N-acetylserine-responsive cysteine regulon transcriptional activator; autorepressor
Escherichia fergusonii Becca 0.32 EFB2_03575 Copper-exporting P-type ATPase 0.67 EFB2_02652 HTH-type transcriptional regulator CysB
Escherichia coli BW25113 0.32 b0484 copA copper transporter (NCBI) 0.67 b1275 cysB DNA-binding transcriptional dual regulator, O-acetyl-L-serine-binding (NCBI)
Escherichia coli ECRC99 0.32 KEDOAH_19895 copA copper-exporting P-type ATPase CopA 0.67 KEDOAH_26165 cysB HTH-type transcriptional regulator CysB
Escherichia coli ECRC102 0.32 NIAGMN_06125 copA copper-exporting P-type ATPase CopA 0.67 NIAGMN_26770 cysB HTH-type transcriptional regulator CysB
Escherichia coli ECRC100 0.32 OKFHMN_08075 copA copper-exporting P-type ATPase CopA 0.67 OKFHMN_02600 cysB HTH-type transcriptional regulator CysB
Escherichia coli ECRC101 0.32 MCAODC_27295 copA copper-exporting P-type ATPase CopA 0.67 MCAODC_15665 cysB HTH-type transcriptional regulator CysB
Escherichia coli ECRC98 0.32 JDDGAC_11720 copA copper-exporting P-type ATPase CopA 0.67 JDDGAC_05145 cysB HTH-type transcriptional regulator CysB
Pantoea sp. MT58 0.32 IAI47_14400 copper-exporting P-type ATPase CopA 0.67 IAI47_09240 HTH-type transcriptional regulator CysB low > 76
Escherichia coli ECOR27 0.32 NOLOHH_01015 copA copper-exporting P-type ATPase CopA 0.67 NOLOHH_20265 cysB HTH-type transcriptional regulator CysB
Escherichia coli Nissle 1917 0.32 ECOLIN_RS02865 copper-exporting P-type ATPase CopA 0.67 ECOLIN_RS07680 HTH-type transcriptional regulator CysB low > 55
Alteromonas macleodii MIT1002 0.32 MIT1002_00284 Copper-exporting P-type ATPase A 0.68 MIT1002_02005 Cys regulon transcriptional activator
Castellaniella sp019104865 MT123 0.32 ABCV34_RS04200 heavy metal translocating P-type ATPase 0.37 ABCV34_RS08230 CysB family HTH-type transcriptional regulator low > 48
Escherichia coli HS(pFamp)R (ATCC 700891) 0.32 OHPLBJKB_03190 Copper-exporting P-type ATPase 0.67 OHPLBJKB_02409 HTH-type transcriptional regulator CysB low > 73
Escherichia coli ECRC62 0.32 BNILDI_22435 copA copper-exporting P-type ATPase CopA 0.67 BNILDI_18415 cysB HTH-type transcriptional regulator CysB
Erwinia tracheiphila SCR3 0.32 LU632_RS15300 copA copper-exporting P-type ATPase CopA 0.67 LU632_RS12550 cysB HTH-type transcriptional regulator CysB
Shewanella loihica PV-4 0.31 Shew_3818 copper-translocating P-type ATPase (RefSeq) 0.66 Shew_1624 cysB transcriptional regulator CysB (RefSeq)
Shewanella sp. ANA-3 0.31 Shewana3_4145 copper-translocating P-type ATPase (RefSeq) 0.65 Shewana3_1731 cysB transcriptional regulator CysB (RefSeq)
Rahnella sp. WP5 0.31 EX31_RS22575 copper-exporting P-type ATPase CopA 0.68 EX31_RS09890 HTH-type transcriptional regulator CysB low > 89
Vibrio cholerae E7946 ATCC 55056 0.31 CSW01_11300 copper-exporting P-type ATPase A 0.70 CSW01_09545 HTH-type transcriptional regulator CysB
Pectobacterium carotovorum WPP14 0.30 HER17_RS15625 copper-exporting P-type ATPase CopA 0.68 HER17_RS10870 HTH-type transcriptional regulator CysB low > 75
Shewanella oneidensis MR-1 0.30 SO1689 cation transport ATPase, E1-E2 family (NCBI ptt file) 0.66 SO2649 cysB cys regulon transcriptional activator (NCBI ptt file) low > 76
Dickeya dianthicola ME23 0.30 DZA65_RS06225 copper-exporting P-type ATPase CopA 0.68 DZA65_RS11020 HTH-type transcriptional regulator CysB low > 75
Rhodanobacter denitrificans FW104-10B01 0.29 LRK54_RS01945 heavy metal translocating P-type ATPase 0.35 LRK54_RS00915 LysR substrate-binding domain-containing protein low > 59

Not shown: 24 genomes with orthologs for PP_0586 only; 5 genomes with orthologs for PP_2327 only