| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Azospirillum sp. SherDot2 | 1.0 | MPMX19_05727 | | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 1.0 | MPMX19_01998 | | 3-isopropylmalate dehydratase large subunit | 0.91 | 11 |
| Azospirillum brasilense Sp245 | 0.83 | AZOBR_RS18325 | | phosphoribosylaminoimidazole-succinocarboxamide synthase | 0.93 | AZOBR_RS03545 | | isopropylmalate isomerase | — | — |
| Bosea sp. OAE506 | 0.70 | ABIE41_RS20895 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.73 | ABIE41_RS11660 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Rhizobium sp. OAE497 | 0.68 | ABIE40_RS15345 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.73 | ABIE40_RS18380 | | 3-isopropylmalate dehydratase large subunit | 0.76 | 20 |
| Agrobacterium fabrum C58 | 0.65 | Atu2548 | | phosphoribosylaminoimidazole-succinocarboxamide synthase | 0.74 | Atu2709 | | 3-isopropylmalate dehydratase, large subunit | 0.83 | 12 |
| Magnetospirillum magneticum AMB-1 | 0.64 | AMB_RS10255 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.80 | AMB_RS20560 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Caulobacter crescentus NA1000 | 0.63 | CCNA_03351 | | phosphoribosylamidoimidazole-succinocarboxamide synthase | 0.69 | CCNA_00196 | | 3-isopropylmalate dehydratase large subunit | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.63 | CCNA_03351 | | phosphoribosylamidoimidazole-succinocarboxamide synthase | 0.69 | CCNA_00196 | | 3-isopropylmalate dehydratase large subunit | low | > 67 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.37 | BT4217 | | phosphoribosylamidoimidazole-succinocarboxamide synthase (NCBI ptt file) | 0.56 | BT1860 | | 3-isopropylmalate dehydratase large subunit (NCBI ptt file) | — | — |
| Bacteroides ovatus ATCC 8483 | 0.37 | BACOVA_05068 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.56 | BACOVA_04603 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Phocaeicola dorei CL03T12C01 | 0.37 | ABI39_RS12675 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.56 | ABI39_RS10200 | | 3-isopropylmalate dehydratase large subunit | 0.75 | 8 |
| Phocaeicola vulgatus CL09T03C04 | 0.37 | HMPREF1058_RS16760 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.56 | HMPREF1058_RS14550 | | 3-isopropylmalate dehydratase large subunit | 0.60 | 36 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.36 | Echvi_3707 | | Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase | 0.54 | Echvi_2059 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Parabacteroides merdae CL09T00C40 | 0.36 | HMPREF1078_RS14210 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.55 | HMPREF1078_RS16660 | | 3-isopropylmalate dehydratase large subunit | low | > 61 |
| Bacteroides stercoris CC31F | 0.36 | HMPREF1181_RS06310 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.56 | HMPREF1181_RS14145 | | 3-isopropylmalate dehydratase large subunit | 0.80 | 44 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.35 | CA265_RS09030 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.54 | CA265_RS15830 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.35 | CA264_09280 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.53 | CA264_09435 | | 3-isopropylmalate dehydratase large subunit | low | > 74 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.34 | ABZR88_RS09265 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.55 | ABZR88_RS11595 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Cellulophaga baltica 18 | 0.34 | M666_RS12890 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.52 | M666_RS15060 | | 3-isopropylmalate dehydratase large subunit | low | > 67 |
| Variovorax sp. SCN45 | 0.29 | GFF5509 | | Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) | 0.68 | GFF3890 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | low | > 127 |
| Variovorax sp. OAS795 | 0.29 | ABID97_RS01730 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.68 | ABID97_RS08465 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Acidovorax sp. GW101-3H11 | 0.29 | Ac3H11_679 | | Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) | 0.66 | Ac3H11_1525 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Rhodanobacter sp000427505 FW510-R12 | 0.29 | LRK53_RS04265 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.55 | LRK53_RS16375 | | 3-isopropylmalate dehydratase large subunit | low | > 59 |
| Methylophilus sp. DMC18 | 0.28 | GFF1712 | | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 0.70 | GFF646 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.28 | LRK54_RS11375 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.57 | LRK54_RS07375 | | 3-isopropylmalate dehydratase large subunit | low | > 59 |
| Rhodanobacter denitrificans MT42 | 0.28 | LRK55_RS11105 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.58 | LRK55_RS07105 | | 3-isopropylmalate dehydratase large subunit | low | > 63 |
| Cupriavidus basilensis FW507-4G11 | 0.28 | RR42_RS03220 | | phosphoribosylaminoimidazole-succinocarboxamide synthase | 0.70 | RR42_RS14400 | | isopropylmalate isomerase | — | — |
| Rhodanobacter sp. FW510-T8 | 0.28 | OKGIIK_12450 | purC | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.51 | OKGIIK_13585 | leuC | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas stutzeri RCH2 | 0.28 | Psest_1517 | | phosphoribosylaminoimidazole-succinocarboxamide synthase | 0.68 | Psest_2591 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Ralstonia sp. UNC404CL21Col | 0.28 | ABZR87_RS08080 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.68 | ABZR87_RS14540 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Ralstonia solanacearum PSI07 | 0.28 | RPSI07_RS21140 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.67 | RPSI07_RS14695 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Ralstonia solanacearum UW163 | 0.28 | UW163_RS01420 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.67 | UW163_RS11105 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Ralstonia solanacearum GMI1000 | 0.28 | RS_RS02875 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.67 | RS_RS10000 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas segetis P6 | 0.28 | MPMX49_01704 | | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 0.66 | MPMX49_03074 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.28 | RALBFv3_RS12190 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.67 | RALBFv3_RS02620 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas sp. S08-1 | 0.27 | OH686_19225 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.67 | OH686_04480 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Burkholderia phytofirmans PsJN | 0.27 | BPHYT_RS16255 | | phosphoribosylaminoimidazole-succinocarboxamide synthase | 0.68 | BPHYT_RS33915 | | isopropylmalate isomerase | 0.51 | 52 |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.27 | DVU0795 | purC | phosphoribosylaminoimidazole-succinocarboxamide synthase (TIGR) | 0.22 | DVU2982 | leuC | 3-isopropylmalate dehydratase / (R)-citramalate isomerase, large subunit LeuC (EC 4.2.1.33; EC 4.2.1.35) (from data) | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.27 | QEN71_RS02440 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.69 | QEN71_RS17605 | | 3-isopropylmalate dehydratase large subunit | low | > 153 |
| Paraburkholderia graminis OAS925 | 0.27 | ABIE53_003425 | | phosphoribosylaminoimidazole-succinocarboxamide synthase | 0.69 | ABIE53_004801 | | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.27 | H281DRAFT_04187 | | phosphoribosylaminoimidazole-succinocarboxamide synthase | 0.69 | H281DRAFT_06075 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Lysobacter sp. OAE881 | 0.27 | ABIE51_RS04125 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.53 | ABIE51_RS17575 | | 3-isopropylmalate dehydratase large subunit | low | > 62 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.27 | Xcc-8004.601.1 | | Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) | 0.66 | Xcc-8004.1049.1 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.61 | 28 |
| Dyella japonica UNC79MFTsu3.2 | 0.26 | ABZR86_RS12215 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.51 | ABZR86_RS15960 | | 3-isopropylmalate dehydratase large subunit | 0.74 | 35 |
| Herbaspirillum seropedicae SmR1 | 0.26 | HSERO_RS03360 | | phosphoribosylaminoimidazole-succinocarboxamide synthase | 0.69 | HSERO_RS16515 | | isopropylmalate isomerase | — | — |
| Desulfovibrio vulgaris Miyazaki F | 0.26 | DvMF_2815 | | phosphoribosylaminoimidazole-succinocarboxamide synthase (RefSeq) | 0.22 | DvMF_1792 | | 3-isopropylmalate dehydratase large subunit (RefSeq) | 0.41 | 51 |
| Dechlorosoma suillum PS | 0.24 | Dsui_0048 | | phosphoribosylaminoimidazole-succinocarboxamide synthase | 0.65 | Dsui_3201 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Castellaniella sp019104865 MT123 | 0.24 | ABCV34_RS00555 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.68 | ABCV34_RS04290 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.24 | GFF2773 | | Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) | 0.68 | GFF3363 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Rhodopseudomonas palustris CGA009 | 0.24 | TX73_002890 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.73 | TX73_001245 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Mycobacterium tuberculosis H37Rv | 0.24 | Rv0780 | | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC (SAICAR synthetase) | 0.62 | Rv2988c | | Probable 3-isopropylmalate dehydratase (large subunit) LeuC (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) | — | — |
| Shewanella oneidensis MR-1 | 0.17 | SO4066 | | phosphoribosylaminoimidazole-succinocarboxamide synthase, putative (NCBI ptt file) | 0.65 | SO4234 | leuC | 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) | 0.88 | 38 |
| Shewanella amazonensis SB2B | 0.17 | Sama_0491 | | phosphoribosylaminoimidazole-succinocarboxamide synthase (RefSeq) | 0.64 | Sama_0337 | | isopropylmalate isomerase large subunit (RefSeq) | 0.77 | 56 |
| Shewanella loihica PV-4 | 0.17 | Shew_2211 | | phosphoribosylaminoimidazole-succinocarboxamidesynthase (RefSeq) | 0.64 | Shew_3470 | | isopropylmalate isomerase large subunit (RefSeq) | 0.83 | 28 |
| Shewanella sp. ANA-3 | 0.17 | Shewana3_3622 | | phosphoribosylaminoimidazole-succinocarboxamide synthase (RefSeq) | 0.65 | Shewana3_3759 | | isopropylmalate isomerase large subunit (RefSeq) | 0.87 | 34 |
| Vibrio cholerae E7946 ATCC 55056 | 0.17 | CSW01_06025 | | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 0.63 | CSW01_12605 | | 3-isopropylmalate dehydratase large subunit | low | > 62 |
Not shown: 0 genomes with orthologs for MPMX19_05727 only; 62 genomes with orthologs for MPMX19_01998 only