Conservation of cofitness between GFF722 and GFF5493 in Hydrogenophaga sp. GW460-11-11-14-LB1

66 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Hydrogenophaga sp. GW460-11-11-14-LB1 1.0 GFF722 NADPH dependent preQ0 reductase (EC 1.7.1.13) 1.0 GFF5493 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) 0.74 18
Acidovorax sp. GW101-3H11 0.79 Ac3H11_1595 NADPH dependent preQ0 reductase (EC 1.7.1.13) 0.47 Ac3H11_2076 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) low > 79
Variovorax sp. SCN45 0.72 GFF6017 NADPH-dependent 7-cyano-7-deazaguanine reductase (EC 1.7.1.13) 0.47 GFF5261 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) low > 127
Variovorax sp. OAS795 0.70 ABID97_RS07920 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.47 ABID97_RS07065 glucose-6-phosphate dehydrogenase low > 91
Burkholderia phytofirmans PsJN 0.59 BPHYT_RS03135 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.70 BPHYT_RS24370 glucose-6-phosphate 1-dehydrogenase low > 109
Ralstonia solanacearum PSI07 0.59 RPSI07_RS21815 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.52 RPSI07_RS07315 glucose-6-phosphate dehydrogenase low > 81
Ralstonia solanacearum GMI1000 0.58 RS_RS02220 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.52 RS_RS24615 glucose-6-phosphate dehydrogenase low > 80
Paraburkholderia sabiae LMG 24235 0.58 QEN71_RS01975 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.70 QEN71_RS08005 glucose-6-phosphate dehydrogenase low > 153
Paraburkholderia bryophila 376MFSha3.1 0.58 H281DRAFT_01889 7-cyano-7-deazaguanine reductase 0.71 H281DRAFT_05358 glucose-6-phosphate 1-dehydrogenase low > 103
Ralstonia solanacearum IBSBF1503 0.57 RALBFv3_RS11390 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.52 RALBFv3_RS16390 glucose-6-phosphate dehydrogenase 0.48 46
Ralstonia solanacearum UW163 0.57 UW163_RS02195 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.52 UW163_RS17130 glucose-6-phosphate dehydrogenase — —
Paraburkholderia graminis OAS925 0.57 ABIE53_000759 7-cyano-7-deazaguanine reductase 0.70 ABIE53_006464 glucose-6-phosphate 1-dehydrogenase low > 113
Cupriavidus basilensis FW507-4G11 0.57 RR42_RS02310 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.52 RR42_RS37405 glucose-6-phosphate dehydrogenase low > 128
Ralstonia sp. UNC404CL21Col 0.55 ABZR87_RS07355 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.52 ABZR87_RS22915 glucose-6-phosphate dehydrogenase low > 80
Herbaspirillum seropedicae SmR1 0.53 HSERO_RS19515 7-cyano-7-deazaguanine reductase 0.55 HSERO_RS05510 glucose-6-phosphate 1-dehydrogenase — —
Rhodanobacter sp. FW510-T8 0.52 OKGIIK_13395 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.52 OKGIIK_14360 zwf glucose-6-phosphate dehydrogenase — —
Dyella japonica UNC79MFTsu3.2 0.51 ABZR86_RS16195 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.51 ABZR86_RS14700 glucose-6-phosphate dehydrogenase low > 74
Rhodanobacter denitrificans MT42 0.51 LRK55_RS10150 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.51 LRK55_RS07600 glucose-6-phosphate dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.51 LRK54_RS10510 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.51 LRK54_RS07870 glucose-6-phosphate dehydrogenase — —
Shewanella loihica PV-4 0.50 Shew_2654 queF 7-cyano-7-deazaguanine reductase (RefSeq) 0.45 Shew_2048 glucose-6-phosphate 1-dehydrogenase (RefSeq) — —
Shewanella oneidensis MR-1 0.50 SO1608 conserved hypothetical protein (NCBI ptt file) 0.46 SO2489 zwf glucose-6-phosphate 1-dehydrogenase (NCBI ptt file) low > 76
Alteromonas macleodii MIT1002 0.49 MIT1002_00988 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.47 MIT1002_02407 Glucose-6-phosphate 1-dehydrogenase low > 70
Shewanella sp. ANA-3 0.49 Shewana3_2835 queF 7-cyano-7-deazaguanine reductase (RefSeq) 0.46 Shewana3_2151 glucose-6-phosphate 1-dehydrogenase (RefSeq) — —
Vibrio cholerae E7946 ATCC 55056 0.49 CSW01_04620 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.39 CSW01_18625 glucose-6-phosphate dehydrogenase low > 62
Rahnella sp. WP5 0.48 EX31_RS13085 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.45 EX31_RS10630 glucose-6-phosphate dehydrogenase — —
Enterobacter asburiae PDN3 0.48 EX28DRAFT_2876 7-cyano-7-deazaguanine reductase 0.44 EX28DRAFT_0704 glucose-6-phosphate 1-dehydrogenase — —
Shewanella amazonensis SB2B 0.48 Sama_1120 queF 7-cyano-7-deazaguanine reductase (RefSeq) 0.45 Sama_1812 glucose-6-phosphate 1-dehydrogenase (RefSeq) — —
Enterobacter sp. TBS_079 0.47 MPMX20_03664 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.44 MPMX20_02757 Glucose-6-phosphate 1-dehydrogenase low > 85
Pseudomonas fluorescens GW456-L13 0.47 PfGW456L13_4015 NADPH dependent preQ0 reductase (EC 1.7.1.13) 0.47 PfGW456L13_1901 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.47 GFF4849 NADPH dependent preQ0 reductase (EC 1.7.1.13) 0.44 GFF1631 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) low > 78
Escherichia fergusonii Becca 0.47 EFB2_01123 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.44 EFB2_02091 Glucose-6-phosphate 1-dehydrogenase low > 86
Pantoea sp. MT58 0.47 IAI47_04050 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.44 IAI47_08495 glucose-6-phosphate dehydrogenase — —
Escherichia coli Nissle 1917 0.47 ECOLIN_RS15580 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.44 ECOLIN_RS10315 glucose-6-phosphate dehydrogenase — —
Klebsiella michiganensis M5al 0.47 BWI76_RS22865 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.44 BWI76_RS18105 glucose-6-phosphate dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.47 OHPLBJKB_00937 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.44 OHPLBJKB_01877 Glucose-6-phosphate 1-dehydrogenase low > 73
Escherichia coli ECRC101 0.47 MCAODC_10715 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.44 MCAODC_19070 zwf glucose-6-phosphate dehydrogenase — —
Escherichia coli ECRC99 0.47 KEDOAH_07940 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.44 KEDOAH_01770 zwf glucose-6-phosphate dehydrogenase — —
Escherichia coli ECOR27 0.47 NOLOHH_12070 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.44 NOLOHH_16845 zwf glucose-6-phosphate dehydrogenase — —
Pseudomonas simiae WCS417 0.47 PS417_07695 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.46 PS417_22110 glucose-6-phosphate dehydrogenase — —
Escherichia coli ECRC101 0.47 OKFHMN_20190 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.44 OKFHMN_26335 zwf glucose-6-phosphate dehydrogenase — —
Pseudomonas syringae pv. syringae B728a 0.47 Psyr_1907 GTP cyclohydrolase I 0.47 Psyr_1120 glucose-6-phosphate 1-dehydrogenase low > 86
Escherichia coli ECOR38 0.47 HEPCGN_19445 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.44 HEPCGN_04740 zwf glucose-6-phosphate dehydrogenase low > 85
Escherichia coli BL21 0.47 ECD_02639 7-cyano-7-deazaguanine reductase (NADPH-dependent) 0.44 ECD_01823 glucose-6-phosphate 1-dehydrogenase — —
Escherichia coli ECRC62 0.47 BNILDI_10575 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.44 BNILDI_15640 zwf glucose-6-phosphate dehydrogenase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.47 Psyr_1907 GTP cyclohydrolase I 0.47 Psyr_1120 glucose-6-phosphate 1-dehydrogenase — —
Escherichia coli ECRC98 0.47 JDDGAC_23855 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.44 JDDGAC_00910 zwf glucose-6-phosphate dehydrogenase — —
Escherichia coli ECRC102 0.47 NIAGMN_17960 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.44 NIAGMN_01725 zwf glucose-6-phosphate dehydrogenase — —
Pseudomonas fluorescens SBW25 0.47 PFLU_RS07770 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.46 PFLU_RS23725 glucose-6-phosphate dehydrogenase low > 109
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_00345 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.47 AO353_03360 glucose-6-phosphate dehydrogenase low > 101
Escherichia coli BW25113 0.47 b2794 yqcD hypothetical protein (NCBI) 0.44 b1852 zwf glucose-6-phosphate 1-dehydrogenase (NCBI) — —
Pseudomonas fluorescens SBW25-INTG 0.47 PFLU_RS07770 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.46 PFLU_RS23725 glucose-6-phosphate dehydrogenase low > 109
Dickeya dadantii 3937 0.46 DDA3937_RS04655 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.44 DDA3937_RS10135 glucose-6-phosphate dehydrogenase low > 74
Dickeya dianthicola 67-19 0.46 HGI48_RS04615 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.44 HGI48_RS10165 glucose-6-phosphate dehydrogenase low > 71
Erwinia tracheiphila SCR3 0.46 LU632_RS06280 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.44 LU632_RS13360 zwf glucose-6-phosphate dehydrogenase low > 74
Dickeya dianthicola ME23 0.46 DZA65_RS04535 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.44 DZA65_RS10580 glucose-6-phosphate dehydrogenase low > 75
Pseudomonas fluorescens FW300-N1B4 0.46 Pf1N1B4_65 NADPH dependent preQ0 reductase (EC 1.7.1.13) 0.47 Pf1N1B4_589 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) — —
Xanthomonas campestris pv. campestris strain 8004 0.46 Xcc-8004.4789.1 NADPH dependent preQ0 reductase (EC 1.7.1.13) 0.36 Xcc-8004.2450.1 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) low > 74
Pseudomonas sp. RS175 0.46 PFR28_01136 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.47 PFR28_00573 Glucose-6-phosphate 1-dehydrogenase low > 88
Pseudomonas sp. S08-1 0.46 OH686_22700 queuine synthase 0.50 OH686_13085 glucose-6-phosphate dehydrogenase low > 80
Pseudomonas fluorescens FW300-N2C3 0.46 AO356_02205 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.47 AO356_05160 glucose-6-phosphate dehydrogenase low > 104
Pseudomonas putida KT2440 0.46 PP_2160 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.51 PP_5351 glucose-6-phosphate 1-dehydrogenase low > 96
Pseudomonas fluorescens FW300-N2E2 0.46 Pf6N2E2_2264 NADPH dependent preQ0 reductase (EC 1.7.1.13) 0.47 Pf6N2E2_2885 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) low > 103
Serratia liquefaciens MT49 0.45 IAI46_21580 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.46 IAI46_14575 glucose-6-phosphate dehydrogenase — —
Pectobacterium carotovorum WPP14 0.45 HER17_RS16390 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.45 HER17_RS11780 glucose-6-phosphate dehydrogenase low > 75
Pseudomonas stutzeri RCH2 0.44 Psest_2714 7-cyano-7-deazaguanine reductase 0.52 Psest_4089 glucose-6-phosphate 1-dehydrogenase low > 67
Lysobacter sp. OAE881 0.43 ABIE51_RS00515 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.49 ABIE51_RS01620 glucose-6-phosphate dehydrogenase — —
Marinobacter adhaerens HP15 0.42 HP15_1463 NADPH-dependent 7-cyano-7-deazaguanine reductase 0.45 HP15_2179 glucose-6-phosphate 1-dehydrogenase low > 73

Not shown: 4 genomes with orthologs for GFF722 only; 24 genomes with orthologs for GFF5493 only