Conservation of cofitness between GFF4211 and GFF1882 in Hydrogenophaga sp. GW460-11-11-14-LB1

67 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Hydrogenophaga sp. GW460-11-11-14-LB1 1.0 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) 1.0 GFF1882 Orotate phosphoribosyltransferase (EC 2.4.2.10) 0.98 2
Variovorax sp. OAS795 0.74 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase 0.71 ABID97_RS03910 orotate phosphoribosyltransferase — —
Acidovorax sp. GW101-3H11 0.74 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.77 Ac3H11_3341 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Variovorax sp. SCN45 0.73 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) 0.71 GFF5065 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Ralstonia sp. UNC404CL21Col 0.56 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase 0.56 ABZR87_RS05590 orotate phosphoribosyltransferase — —
Ralstonia solanacearum IBSBF1503 0.55 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase 0.55 RALBFv3_RS10075 orotate phosphoribosyltransferase — —
Ralstonia solanacearum UW163 0.55 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase 0.55 UW163_RS03505 orotate phosphoribosyltransferase — —
Herbaspirillum seropedicae SmR1 0.55 HSERO_RS16155 dihydroorotate dehydrogenase 0.55 HSERO_RS23380 orotate phosphoribosyltransferase — —
Ralstonia solanacearum PSI07 0.55 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase 0.55 RPSI07_RS23295 orotate phosphoribosyltransferase — —
Ralstonia solanacearum GMI1000 0.55 RS_RS08160 dihydroorotate dehydrogenase (quinone) 0.55 RS_RS00685 orotate phosphoribosyltransferase — —
Castellaniella sp019104865 MT123 0.54 ABCV34_RS07790 quinone-dependent dihydroorotate dehydrogenase 0.54 ABCV34_RS10890 orotate phosphoribosyltransferase — —
Cupriavidus basilensis FW507-4G11 0.53 RR42_RS07465 dihydroorotate dehydrogenase 0.58 RR42_RS01225 orotate phosphoribosyltransferase — —
Dechlorosoma suillum PS 0.51 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 0.53 Dsui_0873 orotate phosphoribosyltransferase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.49 Psyr_2106 dihydroorotate oxidase A 0.44 Psyr_0216 orotate phosphoribosyltransferase — —
Pseudomonas syringae pv. syringae B728a 0.49 Psyr_2106 dihydroorotate oxidase A 0.44 Psyr_0216 orotate phosphoribosyltransferase — —
Alteromonas macleodii MIT1002 0.49 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) 0.47 MIT1002_04070 Orotate phosphoribosyltransferase — —
Pseudomonas fluorescens SBW25-INTG 0.48 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.42 PFLU_RS29475 orotate phosphoribosyltransferase — —
Pseudomonas fluorescens SBW25 0.48 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.42 PFLU_RS29475 orotate phosphoribosyltransferase — —
Pantoea sp. MT58 0.48 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.44 IAI47_00600 orotate phosphoribosyltransferase 0.98 6
Pseudomonas simiae WCS417 0.48 PS417_20935 dihydroorotate dehydrogenase 0.42 PS417_27795 orotate phosphoribosyltransferase — —
Shewanella loihica PV-4 0.48 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) 0.46 Shew_3487 pyrE orotate phosphoribosyltransferase (RefSeq) 0.95 2
Pseudomonas putida KT2440 0.48 PP_2095 Dihydroorotate dehydrogenase (quinone) 0.41 PP_5291 Orotate phosphoribosyltransferase — —
Pseudomonas stutzeri RCH2 0.48 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 0.47 Psest_3810 orotate phosphoribosyltransferase 0.83 2
Pseudomonas sp. RS175 0.48 PFR28_01054 Dihydroorotate dehydrogenase (quinone) 0.44 PFR28_04417 Orotate phosphoribosyltransferase — —
Pseudomonas fluorescens GW456-L13 0.48 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.41 PfGW456L13_788 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Pseudomonas fluorescens FW300-N2E2 0.47 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.42 Pf6N2E2_4370 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Shewanella sp. ANA-3 0.47 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.46 Shewana3_3776 pyrE orotate phosphoribosyltransferase (RefSeq) 0.95 3
Pseudomonas fluorescens FW300-N1B4 0.47 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.42 Pf1N1B4_2120 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_00780 dihydroorotate dehydrogenase (quinone) 0.41 AO353_09245 orotate phosphoribosyltransferase — —
Acinetobacter radioresistens SK82 0.47 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) 0.40 MPMX26_02937 Orotate phosphoribosyltransferase 0.93 8
Pectobacterium carotovorum WPP14 0.47 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.46 HER17_RS20850 orotate phosphoribosyltransferase 0.97 4
Pseudomonas fluorescens FW300-N2C3 0.47 AO356_02610 dihydroorotate dehydrogenase (quinone) 0.42 AO356_12520 orotate phosphoribosyltransferase — —
Shewanella oneidensis MR-1 0.47 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) 0.45 SO4255 pyrE orotate phosphoribosyltransferase (NCBI ptt file) 0.97 2
Shewanella amazonensis SB2B 0.46 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) 0.45 Sama_0321 pyrE orotate phosphoribosyltransferase (RefSeq) 0.91 2
Rahnella sp. WP5 0.46 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.47 EX31_RS14500 orotate phosphoribosyltransferase 0.94 12
Dickeya dadantii 3937 0.46 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase 0.46 DDA3937_RS20535 orotate phosphoribosyltransferase 0.91 3
Dyella japonica UNC79MFTsu3.2 0.46 ABZR86_RS07450 quinone-dependent dihydroorotate dehydrogenase 0.48 ABZR86_RS15640 orotate phosphoribosyltransferase — —
Dickeya dianthicola ME23 0.46 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase 0.45 DZA65_RS00735 orotate phosphoribosyltransferase 0.92 4
Pseudomonas sp. S08-1 0.46 OH686_03120 dihydroorotate dehydrogenase (fumarate) 0.45 OH686_13590 Orotate phosphoribosyltransferase — —
Erwinia tracheiphila SCR3 0.46 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase 0.45 LU632_RS22015 pyrE orotate phosphoribosyltransferase 0.94 4
Kangiella aquimarina DSM 16071 0.46 B158DRAFT_2228 dihydroorotate oxidase A (EC 1.3.3.1) 0.46 B158DRAFT_0786 orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Dickeya dianthicola 67-19 0.46 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase 0.46 HGI48_RS00680 orotate phosphoribosyltransferase 0.69 24
Serratia liquefaciens MT49 0.46 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.47 IAI46_24845 orotate phosphoribosyltransferase 0.87 1
Vibrio cholerae E7946 ATCC 55056 0.46 CSW01_07490 dihydroorotate dehydrogenase (quinone) 0.46 CSW01_01120 orotate phosphoribosyltransferase 0.64 6
Xanthomonas campestris pv. campestris strain 8004 0.46 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.48 Xcc-8004.4884.1 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Lysobacter sp. OAE881 0.46 ABIE51_RS13725 quinone-dependent dihydroorotate dehydrogenase 0.42 ABIE51_RS00065 orotate phosphoribosyltransferase — —
Klebsiella michiganensis M5al 0.45 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.45 BWI76_RS27385 orotate phosphoribosyltransferase 0.94 1
Enterobacter sp. TBS_079 0.45 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.45 MPMX20_00093 Orotate phosphoribosyltransferase 0.98 1
Rhodanobacter denitrificans MT42 0.45 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase 0.43 LRK55_RS08720 orotate phosphoribosyltransferase — —
Enterobacter asburiae PDN3 0.45 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) 0.45 EX28DRAFT_3892 orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Marinobacter adhaerens HP15 0.45 HP15_1377 dihydroorotate dehydrogenase 0.51 HP15_298 orotate phosphoribosyltransferase 0.77 3
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.44 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.45 GFF367 Orotate phosphoribosyltransferase (EC 2.4.2.10) 0.64 2
Escherichia coli ECOR38 0.44 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase 0.45 HEPCGN_14420 pyrE Orotate phosphoribosyltransferase low > 85
Escherichia coli Nissle 1917 0.44 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase 0.45 ECOLIN_RS20750 orotate phosphoribosyltransferase — —
Escherichia fergusonii Becca 0.44 EFB2_03126 Dihydroorotate dehydrogenase (quinone) 0.45 EFB2_00171 Orotate phosphoribosyltransferase low > 86
Escherichia coli ECOR27 0.44 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase 0.44 NOLOHH_07480 pyrE Orotate phosphoribosyltransferase low > 57
Escherichia coli ECRC102 0.44 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.44 NIAGMN_13360 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli BL21 0.44 ECD_00949 dihydro-orotate oxidase, FMN-linked 0.45 ECD_03499 orotate phosphoribosyltransferase 0.76 8
Escherichia coli ECRC101 0.44 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase 0.44 MCAODC_06110 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.44 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) 0.45 OHPLBJKB_00060 Orotate phosphoribosyltransferase 0.69 6
Escherichia coli ECRC99 0.44 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase 0.44 KEDOAH_12550 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECRC101 0.44 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase 0.44 OKFHMN_15600 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli BW25113 0.44 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 0.45 b3642 pyrE orotate phosphoribosyltransferase (NCBI) 0.95 2
Escherichia coli ECRC62 0.44 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.45 BNILDI_04035 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECRC98 0.44 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase 0.44 JDDGAC_19225 pyrE Orotate phosphoribosyltransferase — —
Rhodanobacter denitrificans FW104-10B01 0.44 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase 0.43 LRK54_RS09190 orotate phosphoribosyltransferase — —
Rhodanobacter sp. FW510-T8 0.44 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase 0.43 OKGIIK_15685 pyrE orotate phosphoribosyltransferase — —
Bifidobacterium breve UCC2003 0.18 BBR_RS12895 quinone-dependent dihydroorotate dehydrogenase 0.33 BBR_RS15455 orotate phosphoribosyltransferase low > 34

Not shown: 28 genomes with orthologs for GFF4211 only; 0 genomes with orthologs for GFF1882 only