Conservation of cofitness between ECD_03871 and ECD_04041 in Escherichia coli BL21

71 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_03871 phosphomethylpyrimidine synthase 1.0 ECD_04041 modulator for HflB protease specific for phage lambda cII repressor low > 61
Escherichia coli ECRC98 0.99 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 1.00 JDDGAC_15885 hflK FtsH protease activity modulator HflK low > 86
Escherichia coli ECRC102 0.99 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 1.00 NIAGMN_10095 hflK FtsH protease activity modulator HflK — —
Escherichia coli ECRC100 0.99 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 1.00 OKFHMN_12245 hflK FtsH protease activity modulator HflK low > 80
Escherichia coli ECRC99 0.99 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 1.00 KEDOAH_15910 hflK FtsH protease activity modulator HflK — —
Escherichia coli ECRC101 0.99 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 1.00 MCAODC_02760 hflK FtsH protease activity modulator HflK low > 87
Escherichia coli ECOR27 0.99 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 1.00 NOLOHH_04510 hflK FtsH protease activity modulator HflK low > 75
Escherichia coli Nissle 1917 0.99 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 1.00 ECOLIN_RS24240 FtsH protease activity modulator HflK low > 55
Escherichia coli ECRC62 0.99 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 1.00 BNILDI_06980 hflK FtsH protease activity modulator HflK low > 75
Escherichia coli BW25113 0.99 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 1.00 b4174 hflK modulator for HflB protease specific for phage lambda cII repressor (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 1.00 OHPLBJKB_03868 Modulator of FtsH protease HflK low > 73
Escherichia coli ECOR38 0.99 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 1.00 HEPCGN_10475 hflK FtsH protease activity modulator HflK low > 87
Escherichia fergusonii Becca 0.99 EFB2_04617 Phosphomethylpyrimidine synthase 1.00 EFB2_04361 Modulator of FtsH protease HflK low > 86
Enterobacter sp. TBS_079 0.95 MPMX20_00217 Phosphomethylpyrimidine synthase 0.74 MPMX20_00455 Modulator of FtsH protease HflK low > 85
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.81 EX28DRAFT_3371 HflK protein low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.95 GFF4198 Thiamin biosynthesis protein ThiC 0.83 GFF827 HflK protein 0.36 6
Klebsiella michiganensis M5al 0.93 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.74 BWI76_RS02545 protease modulator HflK low > 92
Pectobacterium carotovorum WPP14 0.87 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.70 HER17_RS02595 FtsH protease activity modulator HflK low > 75
Rahnella sp. WP5 0.86 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.64 EX31_RS08810 FtsH protease activity modulator HflK low > 89
Dickeya dianthicola ME23 0.85 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.69 DZA65_RS19670 FtsH protease activity modulator HflK low > 75
Dickeya dadantii 3937 0.85 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.68 DDA3937_RS18600 FtsH protease activity modulator HflK low > 74
Serratia liquefaciens MT49 0.84 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.69 IAI46_01635 FtsH protease activity modulator HflK low > 86
Dickeya dianthicola 67-19 0.84 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.68 HGI48_RS18535 FtsH protease activity modulator HflK low > 71
Pantoea sp. MT58 0.84 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.67 IAI47_02600 FtsH protease activity modulator HflK low > 76
Erwinia tracheiphila SCR3 0.83 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC 0.67 LU632_RS02065 hflK FtsH protease activity modulator HflK low > 74
Shewanella loihica PV-4 0.77 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.45 Shew_0568 HflK protein (RefSeq) low > 60
Shewanella amazonensis SB2B 0.77 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.46 Sama_3023 hflK protein (RefSeq) low > 62
Shewanella oneidensis MR-1 0.75 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.45 SO0605 hflK hflK protein (NCBI ptt file) low > 76
Alteromonas macleodii MIT1002 0.75 MIT1002_00097 Phosphomethylpyrimidine synthase 0.45 MIT1002_03786 Modulator of FtsH protease HflK low > 70
Shewanella sp. ANA-3 0.74 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.46 Shewana3_0599 HflK protein (RefSeq) low > 73
Vibrio cholerae E7946 ATCC 55056 0.74 CSW01_00335 phosphomethylpyrimidine synthase 0.46 CSW01_01845 protease modulator HflK low > 62
Pseudomonas sp. RS175 0.72 PFR28_05091 Phosphomethylpyrimidine synthase 0.35 PFR28_05123 Modulator of FtsH protease HflK low > 88
Pseudomonas putida KT2440 0.71 PP_4922 Phosphomethylpyrimidine synthase 0.33 PP_4892 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex low > 96
Pseudomonas fluorescens GW456-L13 0.71 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.34 PfGW456L13_152 HflK protein low > 87
Pseudomonas sp. S08-1 0.71 OH686_15885 phosphomethylpyrimidine synthase 0.32 OH686_09460 HflK protein low > 80
Pseudomonas fluorescens FW300-N2E2 0.71 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.34 Pf6N2E2_3612 HflK protein low > 103
Pseudomonas fluorescens FW300-N2C3 0.71 AO356_08810 thiamine biosynthesis protein ThiC 0.35 AO356_08645 hypothetical protein low > 104
Pseudomonas syringae pv. syringae B728a 0.71 Psyr_0544 hydroxymethylpyrimidine synthase 0.34 Psyr_0574 protease FtsH subunit HflK low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.71 Psyr_0544 hydroxymethylpyrimidine synthase 0.34 Psyr_0574 protease FtsH subunit HflK low > 86
Pseudomonas fluorescens FW300-N2E3 0.71 AO353_13010 thiamine biosynthesis protein ThiC 0.35 AO353_13155 hypothetical protein low > 101
Pseudomonas fluorescens SBW25-INTG 0.71 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.36 PFLU_RS02580 FtsH protease activity modulator HflK low > 109
Pseudomonas fluorescens SBW25 0.71 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.36 PFLU_RS02580 FtsH protease activity modulator HflK low > 109
Pseudomonas fluorescens FW300-N1B4 0.71 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.36 Pf1N1B4_1410 HflK protein — —
Pseudomonas simiae WCS417 0.71 PS417_02355 thiamine biosynthesis protein ThiC 0.35 PS417_02500 membrane protein — —
Pseudomonas stutzeri RCH2 0.71 Psest_0477 thiamine biosynthesis protein ThiC 0.34 Psest_0685 HflK protein — —
Marinobacter adhaerens HP15 0.70 HP15_453 thiamine biosynthesis protein thiC 0.33 HP15_2497 HflK low > 73
Dyella japonica UNC79MFTsu3.2 0.69 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC 0.25 ABZR86_RS08355 FtsH protease activity modulator HflK low > 74
Castellaniella sp019104865 MT123 0.69 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC 0.29 ABCV34_RS02660 FtsH protease activity modulator HflK — —
Paraburkholderia sabiae LMG 24235 0.69 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.25 QEN71_RS06010 FtsH protease activity modulator HflK low > 153
Dechlorosoma suillum PS 0.69 Dsui_0422 thiamine biosynthesis protein ThiC 0.32 Dsui_3135 HflK protein — —
Rhodanobacter sp. FW510-T8 0.68 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC 0.28 OKGIIK_06640 hflK FtsH protease activity modulator HflK low > 52
Ralstonia sp. UNC404CL21Col 0.68 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC 0.29 ABZR87_RS10950 FtsH protease activity modulator HflK low > 80
Ralstonia solanacearum GMI1000 0.68 RS_RS00555 phosphomethylpyrimidine synthase 0.28 RS_RS06120 FtsH protease activity modulator HflK low > 80
Ralstonia solanacearum UW163 0.68 UW163_RS03640 phosphomethylpyrimidine synthase ThiC 0.30 UW163_RS12775 FtsH protease activity modulator HflK — —
Ralstonia solanacearum IBSBF1503 0.68 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC 0.30 RALBFv3_RS15310 FtsH protease activity modulator HflK 0.42 69
Ralstonia solanacearum PSI07 0.68 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC 0.30 RPSI07_RS18065 FtsH protease activity modulator HflK low > 81
Xanthomonas campestris pv. campestris strain 8004 0.67 Xcc-8004.1066.1 hypothetical protein 0.22 Xcc-8004.3955.1 HflK protein low > 74
Cupriavidus basilensis FW507-4G11 0.67 RR42_RS01290 thiamine biosynthesis protein ThiC 0.28 RR42_RS13105 membrane protein — —
Kangiella aquimarina DSM 16071 0.67 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.28 B158DRAFT_1954 protease FtsH subunit HflK low > 40
Magnetospirillum magneticum AMB-1 0.65 AMB_RS01125 phosphomethylpyrimidine synthase 0.24 AMB_RS17650 FtsH protease activity modulator HflK — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.64 GFF166 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.28 GFF4856 HflK protein low > 90
Phaeobacter inhibens DSM 17395 0.64 PGA1_c09110 thiamine biosynthesis protein ThiC 0.24 PGA1_c23710 putative protein HflK low > 62
Dinoroseobacter shibae DFL-12 0.64 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) 0.23 Dshi_2736 HflK protein (RefSeq) — —
Variovorax sp. SCN45 0.63 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.27 GFF1002 HflK protein low > 127
Agrobacterium fabrum C58 0.63 Atu2569 thiamine biosynthesis protein 0.22 Atu2045 HFLK protein low > 89
Sinorhizobium meliloti 1021 0.63 SM_b20615 thiamine biosynthesis protein ThiC 0.23 SMc01441 membrane bound protease low > 103
Variovorax sp. OAS795 0.63 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.28 ABID97_RS14260 FtsH protease activity modulator HflK low > 91
Azospirillum sp. SherDot2 0.63 MPMX19_00336 Phosphomethylpyrimidine synthase 0.22 MPMX19_01251 Modulator of FtsH protease HflK — —
Acidovorax sp. GW101-3H11 0.63 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.27 Ac3H11_1801 HflK protein low > 79
Rhodopseudomonas palustris CGA009 0.60 TX73_018540 phosphomethylpyrimidine synthase ThiC 0.25 TX73_018080 FtsH protease activity modulator HflK low > 86
Bosea sp. OAE506 0.60 ABIE41_RS02770 phosphomethylpyrimidine synthase ThiC 0.23 ABIE41_RS12850 FtsH protease activity modulator HflK low > 77
Rhodospirillum rubrum S1H 0.58 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) 0.22 Rru_A2203 HflK (NCBI) — —

Not shown: 22 genomes with orthologs for ECD_03871 only; 3 genomes with orthologs for ECD_04041 only