Conservation of cofitness between ECD_02897 and ECD_02629 in Escherichia coli BL21

63 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_02897 quorum sensing DNA-binding response regulator in two-component regulatory system with QseC 1.0 ECD_02629 (p)ppGpp synthetase I/GTP pyrophosphokinase low > 61
Escherichia fergusonii Becca 1.00 EFB2_00788 Transcriptional regulatory protein QseB 1.00 EFB2_01133 GTP pyrophosphokinase low > 86
Escherichia coli ECOR38 1.00 HEPCGN_17740 Quorum sensing DNA-binding response regulator in two-component regulatory system with QseC 1.00 HEPCGN_19500 relA GTP diphosphokinase low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00677 Transcriptional regulatory protein QseB 1.00 OHPLBJKB_00947 GTP pyrophosphokinase low > 73
Escherichia coli ECOR27 0.99 NOLOHH_10660 Transcriptional regulatory protein QseB 1.00 NOLOHH_12125 relA GTP diphosphokinase low > 75
Escherichia coli ECRC98 0.99 JDDGAC_22515 Transcriptional regulatory protein QseB 1.00 JDDGAC_23915 relA GTP diphosphokinase low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS17425 quorum sensing response regulator transcription factor QseB 1.00 ECOLIN_RS15515 GTP diphosphokinase low > 55
Escherichia coli ECRC100 0.99 OKFHMN_18880 Transcriptional regulatory protein QseB 1.00 OKFHMN_20250 relA GTP diphosphokinase low > 80
Escherichia coli ECRC62 0.99 BNILDI_00855 Transcriptional regulatory protein QseB 1.00 BNILDI_10630 relA GTP diphosphokinase low > 75
Escherichia coli ECRC102 0.99 NIAGMN_16645 Transcriptional regulatory protein QseB 1.00 NIAGMN_18020 relA GTP diphosphokinase
Escherichia coli BW25113 0.99 b3025 qseB DNA-binding response regulator in two-component regulatory system with QseC (NCBI) 1.00 b2784 relA (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) low > 76
Escherichia coli ECRC101 0.99 MCAODC_09395 Transcriptional regulatory protein QseB 1.00 MCAODC_10775 relA GTP diphosphokinase low > 87
Escherichia coli ECRC99 0.99 KEDOAH_09265 Transcriptional regulatory protein QseB 1.00 KEDOAH_07880 relA GTP diphosphokinase
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.89 GFF3138 Two-component system response regulator QseB 0.96 GFF4837 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 low > 78
Klebsiella michiganensis M5al 0.85 BWI76_RS24335 two-component system response regulator QseB 0.94 BWI76_RS22805 GTP diphosphokinase low > 92
Enterobacter asburiae PDN3 0.83 EX28DRAFT_3057 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 0.94 EX28DRAFT_2864 (p)ppGpp synthetase, RelA/SpoT family low > 76
Enterobacter sp. TBS_079 0.83 MPMX20_03863 Transcriptional regulatory protein QseB 0.93 MPMX20_03653 GTP pyrophosphokinase low > 85
Rahnella sp. WP5 0.70 EX31_RS03275 response regulator 0.85 EX31_RS07955 GTP diphosphokinase low > 89
Pantoea sp. MT58 0.70 IAI47_00340 response regulator 0.84 IAI47_04120 GTP diphosphokinase low > 76
Dickeya dianthicola 67-19 0.69 HGI48_RS21345 response regulator 0.87 HGI48_RS17070 GTP diphosphokinase low > 71
Dickeya dianthicola ME23 0.68 DZA65_RS22325 response regulator 0.87 DZA65_RS18145 GTP diphosphokinase low > 75
Serratia liquefaciens MT49 0.68 IAI46_21235 response regulator 0.85 IAI46_03600 GTP diphosphokinase low > 86
Pectobacterium carotovorum WPP14 0.64 HER17_RS21560 response regulator 0.86 HER17_RS04115 GTP diphosphokinase low > 75
Paraburkholderia graminis OAS925 0.52 ABIE53_003418 two-component system response regulator QseB 0.34 ABIE53_002905 GTP pyrophosphokinase low > 113
Burkholderia phytofirmans PsJN 0.52 BPHYT_RS16220 transcriptional regulator 0.35 BPHYT_RS13655 GTP pyrophosphokinase
Paraburkholderia bryophila 376MFSha3.1 0.52 H281DRAFT_04180 two component transcriptional regulator, winged helix family 0.34 H281DRAFT_04499 GTP pyrophosphokinase low > 103
Dechlorosoma suillum PS 0.51 Dsui_3448 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain 0.37 Dsui_2816 (p)ppGpp synthetase, RelA/SpoT family low > 51
Pseudomonas simiae WCS417 0.51 PS417_13595 XRE family transcriptional regulator 0.47 PS417_20150 (p)ppGpp synthetase
Paraburkholderia sabiae LMG 24235 0.50 QEN71_RS02475 response regulator 0.36 QEN71_RS05265 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 153
Pseudomonas sp. RS175 0.50 PFR28_02328 Transcriptional regulatory protein QseB 0.47 PFR28_03223 GTP pyrophosphokinase low > 88
Pseudomonas fluorescens GW456-L13 0.50 PfGW456L13_3169 Two-component system response regulator QseB 0.47 PfGW456L13_2035 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) low > 87
Pseudomonas fluorescens SBW25-INTG 0.50 PFLU_RS15245 response regulator 0.47 PFLU_RS22095 GTP diphosphokinase low > 109
Pseudomonas sp. S08-1 0.50 OH686_04665 Two-component system response regulator QseB 0.47 OH686_18960 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase , (p)ppGpp synthetase I low > 80
Pseudomonas fluorescens FW300-N2C3 0.50 AO356_23845 XRE family transcriptional regulator 0.47 AO356_19060 (p)ppGpp synthetase low > 104
Pseudomonas fluorescens SBW25 0.50 PFLU_RS15245 response regulator 0.47 PFLU_RS22095 GTP diphosphokinase low > 109
Pseudomonas fluorescens FW300-N2E2 0.49 Pf6N2E2_1539 Two-component system response regulator QseB 0.47 Pf6N2E2_5723 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) low > 103
Herbaspirillum seropedicae SmR1 0.49 HSERO_RS21985 transcriptional regulator 0.36 HSERO_RS09855 GTP pyrophosphokinase low > 78
Pseudomonas fluorescens FW300-N1B4 0.49 Pf1N1B4_4454 Two-component system response regulator QseB 0.47 Pf1N1B4_3508 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Cupriavidus basilensis FW507-4G11 0.48 RR42_RS30345 XRE family transcriptional regulator 0.35 RR42_RS06585 GTP pyrophosphokinase low > 128
Ralstonia sp. UNC404CL21Col 0.47 ABZR87_RS22890 response regulator transcription factor 0.36 ABZR87_RS13745 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 80
Pseudomonas putida KT2440 0.47 PP_4225 two component system DNA-binding transcriptional activator QseB 0.46 PP_1656 ATP:GTP 3'-pyrophosphotransferase 0.15 49
Variovorax sp. SCN45 0.47 GFF1175 Two-component system response regulator QseB 0.32 GFF403 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I low > 127
Ralstonia solanacearum GMI1000 0.47 RS_RS24590 DNA-binding response regulator 0.36 RS_RS07930 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 80
Pseudomonas stutzeri RCH2 0.46 Psest_1602 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 0.46 Psest_1640 (p)ppGpp synthetase, RelA/SpoT family low > 67
Ralstonia solanacearum PSI07 0.46 RPSI07_RS07290 DNA-binding response regulator 0.36 RPSI07_RS15685 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 81
Pseudomonas fluorescens FW300-N2E3 0.46 AO353_19370 transcriptional regulator 0.47 AO353_02710 (p)ppGpp synthetase low > 101
Ralstonia solanacearum UW163 0.46 UW163_RS17155 DNA-binding response regulator 0.35 UW163_RS15115 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Ralstonia solanacearum IBSBF1503 0.46 RALBFv3_RS16415 DNA-binding response regulator 0.35 RALBFv3_RS01805 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 76
Acidovorax sp. GW101-3H11 0.45 Ac3H11_3946 Two-component system response regulator QseB 0.33 Ac3H11_362 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I low > 79
Acinetobacter radioresistens SK82 0.44 MPMX26_02034 Transcriptional regulatory protein QseB 0.36 MPMX26_00539 GTP pyrophosphokinase
Rhodanobacter denitrificans MT42 0.43 LRK55_RS13865 response regulator transcription factor 0.39 LRK55_RS12430 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 63
Rhodanobacter denitrificans FW104-10B01 0.43 LRK54_RS14145 response regulator transcription factor 0.39 LRK54_RS12725 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 59
Dyella japonica UNC79MFTsu3.2 0.43 ABZR86_RS20365 response regulator transcription factor 0.40 ABZR86_RS19725 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 74
Shewanella oneidensis MR-1 0.42 SO2104 DNA-binding response regulator YgiX, putative (NCBI ptt file) 0.58 SO3455 relA GTP pyrophosphokinase (NCBI ptt file) 0.21 33
Rhodanobacter sp. FW510-T8 0.42 OKGIIK_14050 ompR DNA-binding response regulator 0.39 OKGIIK_02170 relA GTP diphosphokinase low > 52
Castellaniella sp019104865 MT123 0.42 ABCV34_RS04465 response regulator transcription factor 0.33 ABCV34_RS08440 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 48
Marinobacter adhaerens HP15 0.42 HP15_3968 two component transcriptional regulator, winged helix family 0.45 HP15_791 (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA low > 73
Shewanella sp. ANA-3 0.42 Shewana3_1885 two component transcriptional regulator (RefSeq) 0.59 Shewana3_1111 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) low > 73
Pseudomonas syringae pv. syringae B728a ΔmexB 0.42 Psyr_3212 Response regulator receiver:Transcriptional regulatory protein, C-terminal 0.47 Psyr_3695 RelA/SpoT protein low > 86
Pseudomonas syringae pv. syringae B728a 0.42 Psyr_3212 Response regulator receiver:Transcriptional regulatory protein, C-terminal 0.47 Psyr_3695 RelA/SpoT protein low > 86
Vibrio cholerae E7946 ATCC 55056 0.41 CSW01_19595 DNA-binding response regulator 0.67 CSW01_12405 GTP diphosphokinase low > 62
Lysobacter sp. OAE881 0.40 ABIE51_RS00875 response regulator transcription factor 0.34 ABIE51_RS05170 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 62
Xanthomonas campestris pv. campestris strain 8004 0.37 Xcc-8004.4942.1 Two-component system regulatory protein 0.36 Xcc-8004.1489.1 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I low > 74
Bacteroides stercoris CC31F 0.33 HMPREF1181_RS11775 response regulator transcription factor 0.23 HMPREF1181_RS16240 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 56

Not shown: 10 genomes with orthologs for ECD_02897 only; 10 genomes with orthologs for ECD_02629 only