Conservation of cofitness between ECD_03780 and ECD_02031 in Escherichia coli BL21

65 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_03780 formate dehydrogenase formation protein 1.0 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase 0.43 9
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_04155 Sulfur carrier protein FdhD 1.00 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 73
Escherichia coli BW25113 0.99 b3895 fdhD formate dehydrogenase accessory protein (NCBI) 1.00 b2103 thiD phosphomethylpyrimidine kinase (NCBI) low > 76
Escherichia coli ECOR38 0.99 HEPCGN_12585 fdhD formate dehydrogenase accessory sulfurtransferase FdhD 0.99 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 85
Escherichia coli ECRC102 0.99 NIAGMN_11705 fdhD formate dehydrogenase accessory sulfurtransferase FdhD 0.99 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECOR27 0.99 NOLOHH_06070 fdhD formate dehydrogenase accessory sulfurtransferase FdhD 1.00 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 57
Escherichia coli ECRC99 0.99 KEDOAH_14205 fdhD formate dehydrogenase accessory sulfurtransferase FdhD 0.99 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC101 0.99 MCAODC_04450 fdhD formate dehydrogenase accessory sulfurtransferase FdhD 0.99 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC101 0.99 OKFHMN_13950 fdhD formate dehydrogenase accessory sulfurtransferase FdhD 0.99 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC62 0.99 BNILDI_05455 fdhD formate dehydrogenase accessory sulfurtransferase FdhD 1.00 BNILDI_14330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli Nissle 1917 0.99 ECOLIN_RS22460 formate dehydrogenase accessory sulfurtransferase FdhD 0.98 ECOLIN_RS12335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia fergusonii Becca 0.99 EFB2_04720 Sulfur carrier protein FdhD 0.99 EFB2_01754 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 86
Escherichia coli ECRC98 0.98 JDDGAC_17575 fdhD formate dehydrogenase accessory sulfurtransferase FdhD 0.99 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Klebsiella michiganensis M5al 0.83 BWI76_RS00475 sulfurtransferase FdhD 0.92 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 92
Enterobacter asburiae PDN3 0.78 EX28DRAFT_4379 formate dehydrogenase family accessory protein FdhD 0.90 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Enterobacter sp. TBS_079 0.78 MPMX20_04574 Sulfur carrier protein FdhD 0.90 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.77 GFF2254 Formate dehydrogenase chain D (EC 1.2.1.2) 0.91 GFF3834 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 78
Pantoea sp. MT58 0.73 IAI47_18740 formate dehydrogenase accessory sulfurtransferase FdhD 0.75 IAI47_06810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Pectobacterium carotovorum WPP14 0.72 HER17_RS21105 formate dehydrogenase accessory sulfurtransferase FdhD 0.78 HER17_RS06265 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Serratia liquefaciens MT49 0.71 IAI46_00205 formate dehydrogenase accessory sulfurtransferase FdhD 0.77 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 86
Dickeya dadantii 3937 0.71 DDA3937_RS20955 formate dehydrogenase accessory sulfurtransferase FdhD 0.75 DDA3937_RS15335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 74
Rahnella sp. WP5 0.71 EX31_RS05780 formate dehydrogenase accessory sulfurtransferase FdhD 0.78 EX31_RS20390 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 89
Dickeya dianthicola 67-19 0.70 HGI48_RS00290 formate dehydrogenase accessory sulfurtransferase FdhD 0.75 HGI48_RS15410 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 71
Dickeya dianthicola ME23 0.70 DZA65_RS00290 formate dehydrogenase accessory sulfurtransferase FdhD 0.74 DZA65_RS16235 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Herbaspirillum seropedicae SmR1 0.44 HSERO_RS07435 formate dehydrogenase accessory protein FdhD 0.19 HSERO_RS02135 phosphomethylpyrimidine kinase low > 78
Cupriavidus basilensis FW507-4G11 0.43 RR42_RS03765 formate dehydrogenase 0.32 RR42_RS01370 phosphomethylpyrimidine kinase — —
Azospirillum brasilense Sp245 0.40 AZOBR_RS18415 formate dehydrogenase accessory protein FdhD 0.37 AZOBR_RS07045 phosphomethylpyrimidine kinase — —
Azospirillum sp. SherDot2 0.39 MPMX19_03500 Sulfur carrier protein FdhD 0.35 MPMX19_06182 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Dyella japonica UNC79MFTsu3.2 0.37 ABZR86_RS03590 formate dehydrogenase accessory sulfurtransferase FdhD 0.29 ABZR86_RS00760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum IBSBF1503 0.36 RALBFv3_RS18750 sulfurtransferase FdhD 0.34 RALBFv3_RS09905 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum UW163 0.36 UW163_RS20380 sulfurtransferase FdhD 0.34 UW163_RS03675 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Paraburkholderia bryophila 376MFSha3.1 0.36 H281DRAFT_06437 FdhD protein 0.53 H281DRAFT_00587 hydroxymethylpyrimidine kinase /phosphomethylpyrimidine kinase — —
Ralstonia solanacearum PSI07 0.35 RPSI07_RS04845 sulfurtransferase FdhD 0.34 RPSI07_RS23455 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Xanthomonas campestris pv. campestris strain 8004 0.35 Xcc-8004.2194.1 Formate dehydrogenase chain D (EC 1.2.1.2) 0.30 Xcc-8004.3091.1 hypothetical protein low > 74
Ralstonia solanacearum GMI1000 0.35 RS_RS22200 sulfurtransferase FdhD 0.35 RS_RS00495 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia sp. UNC404CL21Col 0.34 ABZR87_RS19685 formate dehydrogenase accessory sulfurtransferase FdhD 0.35 ABZR87_RS04830 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Burkholderia phytofirmans PsJN 0.34 BPHYT_RS03240 formate dehydrogenase accessory protein FdhD 0.53 BPHYT_RS12250 phosphomethylpyrimidine kinase — —
Rhodopseudomonas palustris CGA009 0.33 TX73_003800 formate dehydrogenase accessory sulfurtransferase FdhD 0.48 TX73_020570 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Rhizobium sp. OAE497 0.33 ABIE40_RS17840 formate dehydrogenase accessory sulfurtransferase FdhD 0.49 ABIE40_RS25930 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 107
Paraburkholderia sabiae LMG 24235 0.33 QEN71_RS02080 formate dehydrogenase accessory sulfurtransferase FdhD 0.54 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Castellaniella sp019104865 MT123 0.33 ABCV34_RS00240 formate dehydrogenase accessory sulfurtransferase FdhD 0.42 ABCV34_RS14505 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Sinorhizobium meliloti 1021 0.32 SMc03085 formate dehydrogenase accessory protein 0.43 SM_b20962 phoshomethylpyrimidine kinase low > 103
Agrobacterium fabrum C58 0.32 Atu2619 NAD-dependent formate dehydrogenase, C subunit protein 0.45 Atu3290 phosphomethylpyrimidine kinase low > 89
Paraburkholderia graminis OAS925 0.32 ABIE53_000787 FdhD protein 0.51 ABIE53_002529 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Pseudomonas fluorescens FW300-N2E3 0.32 AO353_11830 formate dehydrogenase family accessory protein FdhD 0.23 AO353_06350 hydrogenase low > 101
Pseudomonas sp. RS175 0.31 PFR28_04882 Sulfur carrier protein FdhD 0.20 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 88
Pseudomonas putida KT2440 0.31 PP_0257 protein sulfur transferase 0.22 PP_4782 Phosphomethylpyrimidine kinase low > 96
Pseudomonas simiae WCS417 0.31 PS417_01270 iron ABC transporter substrate-binding protein 0.24 PS417_24600 hydrogenase low > 88
Pseudomonas fluorescens FW300-N1B4 0.31 Pf1N1B4_1673 Formate dehydrogenase chain D (EC 1.2.1.2) 0.18 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 87
Pseudomonas syringae pv. syringae B728a 0.31 Psyr_4945 Formate dehydrogenase, subunit FdhD 0.22 Psyr_4340 phosphomethylpyrimidine kinase, putative low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.31 Psyr_4945 Formate dehydrogenase, subunit FdhD 0.22 Psyr_4340 phosphomethylpyrimidine kinase, putative low > 86
Pseudomonas fluorescens GW456-L13 0.31 PfGW456L13_408 Formate dehydrogenase chain D (EC 1.2.1.2) 0.22 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 87
Pseudomonas fluorescens FW300-N2C3 0.31 AO356_10100 formate dehydrogenase family accessory protein FdhD 0.22 AO356_15435 hydrogenase low > 104
Pseudomonas fluorescens SBW25-INTG 0.30 PFLU_RS01365 formate dehydrogenase accessory sulfurtransferase FdhD 0.24 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 109
Pseudomonas fluorescens FW300-N2E2 0.30 Pf6N2E2_3890 Formate dehydrogenase chain D (EC 1.2.1.2) 0.18 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 103
Pseudomonas fluorescens SBW25 0.30 PFLU_RS01365 formate dehydrogenase accessory sulfurtransferase FdhD 0.24 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 109
Pseudomonas stutzeri RCH2 0.28 Psest_3964 formate dehydrogenase family accessory protein FdhD 0.21 Psest_0537 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 67
Bosea sp. OAE506 0.28 ABIE41_RS15275 formate dehydrogenase accessory sulfurtransferase FdhD 0.44 ABIE41_RS21620 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Sphingomonas koreensis DSMZ 15582 0.26 Ga0059261_3871 formate dehydrogenase family accessory protein FdhD 0.24 Ga0059261_1961 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Caulobacter crescentus NA1000 0.24 CCNA_01300 formate dehydrogenase accessory protein fdhD 0.33 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase — —
Caulobacter crescentus NA1000 Δfur 0.24 CCNA_01300 formate dehydrogenase accessory protein fdhD 0.33 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.18 ABZR88_RS07865 formate dehydrogenase accessory sulfurtransferase FdhD 0.32 ABZR88_RS08810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 71
Mycobacterium tuberculosis H37Rv 0.17 Rv2899c Possible FdhD protein homolog 0.25 Rv0422c Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase) — —
Desulfovibrio vulgaris Hildenborough JW710 0.12 DVU0578 formate dehydrogenase accessory protein FdhD, putative (TIGR) 0.27 DVU0931 thiD phosphomethylpyrimidine kinase (TIGR) — —
Vibrio cholerae E7946 ATCC 55056 0.11 CSW01_07625 sulfurtransferase FdhD 0.39 CSW01_06545 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 62
Acidovorax sp. GW101-3H11 0.09 Ac3H11_3797 Formate dehydrogenase chain D (EC 1.2.1.2) 0.33 Ac3H11_1063 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) — —

Not shown: 8 genomes with orthologs for ECD_03780 only; 24 genomes with orthologs for ECD_02031 only