| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_02845 | | cysteine synthase CysM | 1.0 | CSW01_05290 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.56 | 14 |
| Shewanella sp. ANA-3 | 0.82 | Shewana3_3188 | cysM | cysteine synthase B (RefSeq) | 0.69 | Shewana3_3274 | | cob(I)yrinic acid a,c-diamide adenosyltransferase (RefSeq) | low | > 73 |
| Shewanella oneidensis MR-1 | 0.79 | SO3598 | cysM | cysteine synthase B (NCBI ptt file) | 0.67 | SO1039 | cobO | cob(I)alamin adenosyltransferase (NCBI ptt file) | low | > 76 |
| Pseudomonas stutzeri RCH2 | 0.76 | Psest_1638 | | cysteine synthase B | 0.50 | Psest_3014 | | cob(I)alamin adenosyltransferase | — | — |
| Pseudomonas sp. BP01 | 0.75 | JOY50_RS23900 | cysM | cysteine synthase CysM | 0.48 | JOY50_RS27940 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.65 | 70 |
| Pseudomonas segetis P6 | 0.75 | ACVTMO_RS08185 | cysM | cysteine synthase CysM | 0.48 | ACVTMO_RS09015 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Pseudomonas aeruginosa PA14 | 0.75 | IKLFDK_04190 | | cysteine synthase B | 0.48 | IKLFDK_06030 | | cob(I)yrinic acid a c-diamide adenosyltransferase | — | — |
| Pseudomonas aeruginosa MRSN321 | 0.75 | DY961_RS07785 | cysM;go_function=cysteine | cysteine synthase B | 0.48 | DY961_RS06050 | cobO;go_function=corrinoid | cob(I)yrinic acid a c-diamide adenosyltransferase | low | > 100 |
| Pseudomonas aeruginosa PUPa3 | 0.75 | DQ20_RS45010 | cysM;go_function=cysteine | cysteine synthase B | 0.48 | DQ20_RS46730 | cobO;go_function=corrinoid | cob(I)yrinic acid a c-diamide adenosyltransferase | low | > 101 |
| Pseudomonas sp. SVBP6 | 0.75 | COO64_RS07335 | cysM | cysteine synthase CysM | 0.48 | COO64_RS07250 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 93 |
| Pseudomonas sp. S08-1 | 0.74 | OH686_18950 | | cysteine synthase B | 0.51 | OH686_04990 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Pseudomonas putida KT2440 | 0.74 | PP_1654 | | cysteine synthase B | 0.48 | PP_1672 | | cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase | low | > 96 |
| Pseudomonas sp. RS175 | 0.74 | PFR28_03225 | | Cysteine synthase B | 0.48 | PFR28_03209 | | Corrinoid adenosyltransferase | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.74 | PfGW456L13_2032 | | Cysteine synthase B (EC 2.5.1.47) | 0.49 | PfGW456L13_4243 | | Cob(I)alamin adenosyltransferase (EC 2.5.1.17) | low | > 87 |
| Pseudomonas fluorescens FW300-N2E2 | 0.74 | Pf6N2E2_5721 | | Cysteine synthase B (EC 2.5.1.47) | 0.51 | Pf6N2E2_5737 | | Cob(I)alamin adenosyltransferase (EC 2.5.1.17) | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.74 | AO353_02720 | | cysteine synthase | 0.51 | AO353_02640 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 101 |
| Pseudomonas lactucae CFBP13502 | 0.73 | GEMAOFIL_04225 | | Cysteine synthase B | 0.49 | GEMAOFIL_04210 | | Corrinoid adenosyltransferase | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.73 | Pf1N1B4_3506 | | Cysteine synthase B (EC 2.5.1.47) | 0.48 | Pf1N1B4_3706 | | Cob(I)alamin adenosyltransferase (EC 2.5.1.17) | — | — |
| Pseudomonas sp. DMC3 | 0.73 | GFF4820 | | Cysteine synthase B | 0.51 | GFF2547 | | Corrinoid adenosyltransferase | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.73 | AO356_19050 | | cysteine synthase | 0.49 | AO356_19135 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.39 | 91 |
| Pseudomonas fluorescens SBW25-INTG | 0.73 | PFLU_RS22105 | | cysteine synthase CysM | 0.48 | PFLU_RS22030 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.73 | PFLU_RS22105 | | cysteine synthase CysM | 0.48 | PFLU_RS22030 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Pseudomonas simiae WCS417 | 0.72 | PS417_20160 | | cysteine synthase | 0.49 | PS417_20065 | | Cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Pseudomonas orientalis W4I3 | 0.72 | QF045_RS22270 | | cysteine synthase CysM | 0.48 | QF045_RS22180 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Klebsiella pneumoniae MKP103 | 0.72 | KDGMDA_27525 | | cysteine synthase B | 0.63 | KDGMDA_19595 | | cob(I)yrinic acid a c-diamide adenosyltransferase | low | > 95 |
| Rahnella sp. WP5 | 0.72 | EX31_RS20205 | | cysteine synthase CysM | 0.70 | EX31_RS09915 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 89 |
| Enterobacter asburiae PDN3 | 0.72 | EX28DRAFT_0209 | | cysteine synthase B | 0.68 | EX28DRAFT_0941 | | cob(I)alamin adenosyltransferase | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.72 | Psyr_3697 | | cysteine synthase | 0.47 | Psyr_3681 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.72 | Psyr_3697 | | cysteine synthase | 0.47 | Psyr_3681 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Enterobacter sp. TBS_079 | 0.71 | MPMX20_03313 | | Cysteine synthase B | 0.68 | MPMX20_02506 | | Corrinoid adenosyltransferase | — | — |
| Escherichia coli BL21 | 0.71 | ECD_02321 | | cysteine synthase B (O-acetylserine sulfhydrolase B) | 0.72 | ECD_01246 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 61 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.71 | OHPLBJKB_01302 | | Cysteine synthase B | 0.72 | OHPLBJKB_02414 | | Cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.34 | 37 |
| Klebsiella michiganensis M5al | 0.71 | BWI76_RS20685 | | cysteine synthase B | 0.70 | BWI76_RS11900 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Escherichia coli ECRC62 | 0.71 | BNILDI_12715 | cysM | cysteine synthase B | 0.72 | BNILDI_18440 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 75 |
| Escherichia coli ECOR27 | 0.71 | NOLOHH_13850 | cysM | cysteine synthase B | 0.72 | NOLOHH_20290 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 76 |
| Escherichia fergusonii Becca | 0.71 | EFB2_01456 | | Cysteine synthase B | 0.72 | EFB2_02657 | | Corrinoid adenosyltransferase | low | > 86 |
| Escherichia coli Nissle 1917 | 0.71 | ECOLIN_RS13900 | | cysteine synthase B | 0.72 | ECOLIN_RS07640 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Escherichia coli ECRC100 | 0.71 | OKFHMN_22170 | cysM | cysteine synthase B | 0.71 | OKFHMN_02625 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 79 |
| Escherichia coli ECOR38 | 0.71 | HEPCGN_21345 | cysM | cysteine synthase B | 0.71 | HEPCGN_25575 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 88 |
| Escherichia coli BW25113 | 0.71 | b2421 | cysM | cysteine synthase B (O-acetylserine sulfhydrolase B) (NCBI) | 0.72 | b1270 | btuR | cob(I)yrinic acid a,c-diamide adenosyltransferase (NCBI) | low | > 76 |
| Escherichia coli ECRC101 | 0.71 | MCAODC_12700 | cysM | cysteine synthase B | 0.71 | MCAODC_15640 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 87 |
| Escherichia coli ECRC98 | 0.71 | JDDGAC_26120 | cysM | cysteine synthase B | 0.71 | JDDGAC_05170 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 87 |
| Escherichia coli ECRC102 | 0.71 | NIAGMN_19940 | cysM | cysteine synthase B | 0.71 | NIAGMN_26795 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 80 |
| Escherichia coli ECRC99 | 0.71 | KEDOAH_06050 | cysM | cysteine synthase B | 0.71 | KEDOAH_26140 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.71 | GFF2055 | | Cysteine synthase (EC 2.5.1.47) | 0.69 | GFF2718 | | Cob(I)alamin adenosyltransferase (EC 2.5.1.17) | low | > 78 |
| Serratia liquefaciens MT49 | 0.69 | IAI46_18490 | | cysteine synthase CysM | 0.67 | IAI46_13990 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 87 |
| Methylophilus sp. DMC18 | 0.68 | GFF907 | | Cysteine synthase B | 0.48 | GFF1478 | | Corrinoid adenosyltransferase | — | — |
| Pectobacterium carotovorum WPP14 | 0.68 | HER17_RS17210 | | cysteine synthase CysM | 0.70 | HER17_RS10895 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 75 |
| Variovorax sp. SCN45 | 0.67 | GFF6025 | | Cysteine synthase B (EC 2.5.1.47) | 0.33 | GFF444 | | Cob(I)alamin adenosyltransferase (EC 2.5.1.17) @ Cob(I)alamin adenosyltransferase (EC 2.5.1.17), clustered with cobalamin synthesis | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.66 | RALBFv3_RS13825 | | cysteine synthase CysM | 0.40 | RALBFv3_RS20540 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Pantoea sp. MT58 | 0.66 | IAI47_05405 | | cysteine synthase CysM | 0.69 | IAI47_09215 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 76 |
| Ralstonia solanacearum UW163 | 0.66 | UW163_RS15985 | | cysteine synthase CysM | 0.40 | UW163_RS18635 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Variovorax sp. OAS795 | 0.66 | ABID97_RS07880 | | cysteine synthase CysM | 0.32 | ABID97_RS17395 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Pantoea agglomerans CFBP13505 P0401 | 0.66 | PagCFBP13505_RS19950 | | cysteine synthase CysM | 0.69 | PagCFBP13505_RS06970 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 74 |
| Acidovorax sp. GW101-3H11 | 0.66 | Ac3H11_644 | | Cysteine synthase B (EC 2.5.1.47) | 0.32 | Ac3H11_994 | | Cob(I)alamin adenosyltransferase (EC 2.5.1.17) | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.66 | GFF709 | | Cysteine synthase B (EC 2.5.1.47) | 0.34 | GFF3983 | | Cob(I)alamin adenosyltransferase (EC 2.5.1.17) | low | > 90 |
| Dickeya dianthicola ME23 | 0.66 | DZA65_RS04315 | | cysteine synthase CysM | 0.67 | DZA65_RS10985 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 75 |
| Ralstonia solanacearum GMI1000 | 0.66 | RS_RS04560 | | cysteine synthase CysM | 0.41 | RS_RS20065 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Dickeya dadantii 3937 | 0.66 | DDA3937_RS04425 | | cysteine synthase CysM | 0.67 | DDA3937_RS10505 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 74 |
| Ralstonia solanacearum PSI07 | 0.66 | RPSI07_RS19645 | | cysteine synthase CysM | 0.41 | RPSI07_RS02200 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Dechlorosoma suillum PS | 0.66 | Dsui_1954 | | cysteine synthase B | 0.46 | Dsui_0532 | | cob(I)alamin adenosyltransferase | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.65 | H281DRAFT_03911 | | cysteine synthase | 0.41 | H281DRAFT_06529 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.65 | QEN71_RS04135 | | cysteine synthase CysM | 0.40 | QEN71_RS08695 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Dickeya dianthicola 67-19 | 0.65 | HGI48_RS04400 | | cysteine synthase CysM | 0.67 | HGI48_RS10505 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 71 |
| Ralstonia sp. UNC404CL21Col | 0.65 | ABZR87_RS09515 | | cysteine synthase CysM | 0.47 | ABZR87_RS00080 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 80 |
| Herbaspirillum seropedicae SmR1 | 0.64 | HSERO_RS04915 | | cysteine synthase | 0.39 | HSERO_RS13260 | | cobinamide adenolsyltransferase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.64 | RR42_RS04535 | | cysteine synthase | 0.52 | RR42_RS16125 | | Cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 128 |
| Burkholderia phytofirmans PsJN | 0.63 | BPHYT_RS14845 | | cysteine synthase | 0.40 | BPHYT_RS24825 | | cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase | — | — |
| Paraburkholderia graminis OAS925 | 0.63 | ABIE53_003144 | | cysteine synthase B | 0.41 | ABIE53_006184 | | cob(I)alamin adenosyltransferase | low | > 113 |
| Lysobacter sp. OAE881 | 0.35 | ABIE51_RS15860 | | cysteine synthase A | 0.45 | ABIE51_RS04945 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 62 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.34 | Xcc-8004.1247.1 | | Cysteine synthase (EC 2.5.1.47) | 0.49 | Xcc-8004.1393.1 | | Cob(I)alamin adenosyltransferase (EC 2.5.1.17) | low | > 74 |
| Dyella japonica UNC79MFTsu3.2 | 0.33 | ABZR86_RS05875 | | cysteine synthase A | 0.45 | ABZR86_RS10920 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | low | > 74 |
| Fusobacterium nucleatum SB010 | 0.30 | HUW76_04155 | | cysteine synthase A | 0.27 | HUW76_00780 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | — | — |
| Dinoroseobacter shibae DFL-12 | 0.28 | Dshi_2314 | | Pyridoxal-5'-phosphate-dependent protein beta subunit (RefSeq) | 0.40 | Dshi_0157 | | cob(I)alamin adenosyltransferase (RefSeq) | — | — |
| Phaeobacter inhibens DSM 17395 | 0.27 | PGA1_c13950 | | cysteine synthase CysK | 0.42 | PGA1_c08200 | | cob(I)yrinic acid a,c-diamide adenosyltransferase CobO | — | — |
Not shown: 17 genomes with orthologs for CSW01_02845 only; 21 genomes with orthologs for CSW01_05290 only