Conservation of cofitness between CSW01_12405 and CSW01_02775 in Vibrio cholerae E7946 ATCC 55056

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_12405 GTP diphosphokinase 1.0 CSW01_02775 glycerol-3-phosphate acyltransferase 0.45 12
Dickeya dianthicola 67-19 0.67 HGI48_RS17070 GTP diphosphokinase 0.62 HGI48_RS17185 glycerol-3-phosphate 1-O-acyltransferase PlsY low > 71
Dickeya dadantii 3937 0.67 DDA3937_RS17015 GTP diphosphokinase 0.62 DDA3937_RS17135 glycerol-3-phosphate 1-O-acyltransferase PlsY low > 74
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.67 GFF4837 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 0.64 GFF3173 Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY low > 78
Dickeya dianthicola ME23 0.67 DZA65_RS18145 GTP diphosphokinase 0.63 DZA65_RS18270 glycerol-3-phosphate 1-O-acyltransferase PlsY low > 75
Klebsiella pneumoniae MKP103 0.67 KDGMDA_03335 GTP diphosphokinase 0.63 KDGMDA_05300 glycerol-3-phosphate 1-O-acyltransferase PlsY low > 94
Klebsiella pneumoniae MRSN742743 0.67 GJGHJB_00976 relA GTP diphosphokinase 0.64 GJGHJB_00654 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY low > 83
Escherichia coli Nissle 1917 0.67 ECOLIN_RS15515 GTP diphosphokinase 0.63 ECOLIN_RS17665 glycerol-3-phosphate 1-O-acyltransferase PlsY low > 55
Escherichia coli ECRC101 0.67 MCAODC_10775 relA GTP diphosphokinase 0.63 MCAODC_09210 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY low > 87
Escherichia coli ECOR27 0.67 NOLOHH_12125 relA GTP diphosphokinase 0.63 NOLOHH_10485 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY low > 75
Escherichia coli ECRC99 0.67 KEDOAH_07880 relA GTP diphosphokinase 0.63 KEDOAH_09450 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY
Escherichia coli ECRC102 0.67 NIAGMN_18020 relA GTP diphosphokinase 0.63 NIAGMN_16460 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY low > 80
Escherichia coli BL21 0.67 ECD_02629 (p)ppGpp synthetase I/GTP pyrophosphokinase 0.63 ECD_02929 putative glycerol-3-phosphate acyltransferase low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.67 OHPLBJKB_00947 GTP pyrophosphokinase 0.63 OHPLBJKB_00645 putative glycerol-3-phosphate acyltransferase low > 74
Escherichia coli ECOR38 0.67 HEPCGN_19500 relA GTP diphosphokinase 0.63 HEPCGN_17550 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY low > 88
Escherichia coli ECRC100 0.67 OKFHMN_20250 relA GTP diphosphokinase 0.63 OKFHMN_18695 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY low > 79
Escherichia coli BW25113 0.67 b2784 relA (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) 0.63 b3059 ygiH hypothetical protein (NCBI) low > 76
Escherichia coli ECRC98 0.67 JDDGAC_23915 relA GTP diphosphokinase 0.63 JDDGAC_22330 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY low > 87
Escherichia coli ECRC62 0.67 BNILDI_10630 relA GTP diphosphokinase 0.63 BNILDI_01030 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY low > 75
Escherichia fergusonii Becca 0.67 EFB2_01133 GTP pyrophosphokinase 0.63 EFB2_00752 putative glycerol-3-phosphate acyltransferase low > 86
Klebsiella michiganensis M5al 0.67 BWI76_RS22805 GTP diphosphokinase 0.61 BWI76_RS24490 glycerol-3-phosphate acyltransferase low > 92
Pantoea sp. MT58 0.66 IAI47_04120 GTP diphosphokinase 0.63 IAI47_03070 glycerol-3-phosphate 1-O-acyltransferase PlsY low > 76
Enterobacter sp. TBS_079 0.66 MPMX20_03653 GTP pyrophosphokinase 0.63 MPMX20_03896 putative glycerol-3-phosphate acyltransferase low > 85
Erwinia tracheiphila HP pepo 2.2 0.66 IJEDHG_17375 relA GTP diphosphokinase 0.62 IJEDHG_14355 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY low > 61
Enterobacter asburiae PDN3 0.66 EX28DRAFT_2864 (p)ppGpp synthetase, RelA/SpoT family 0.63 EX28DRAFT_3087 acyl-phosphate glycerol 3-phosphate acyltransferase low > 76
Erwinia tracheiphila SCR3 0.66 LU632_RS06350 relA GTP diphosphokinase 0.62 LU632_RS20705 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY low > 73
Erwinia amylovora T8 0.66 OLJFJH_09245 GTP diphosphokinase 0.61 OLJFJH_07605 glycerol-3-phosphate 1-O-acyltransferase PlsY low > 58
Pantoea agglomerans CFBP13505 P0401 0.66 PagCFBP13516_RS04390 relA GTP diphosphokinase 0.64 PagCFBP13516_RS03310 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY low > 80
Rahnella sp. WP5 0.66 EX31_RS07955 GTP diphosphokinase 0.63 EX31_RS08175 glycerol-3-phosphate 1-O-acyltransferase PlsY low > 89
Pectobacterium carotovorum WPP14 0.66 HER17_RS04115 GTP diphosphokinase 0.64 HER17_RS04005 glycerol-3-phosphate 1-O-acyltransferase PlsY low > 75
Serratia liquefaciens MT49 0.66 IAI46_03600 GTP diphosphokinase 0.65 IAI46_22090 glycerol-3-phosphate 1-O-acyltransferase PlsY low > 87
Shewanella amazonensis SB2B 0.57 Sama_1033 GTP diphosphokinase (RefSeq) 0.53 Sama_0828 putative glycerol-3-phosphate acyltransferase PlsY (RefSeq) low > 62
Shewanella sp. ANA-3 0.56 Shewana3_1111 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) 0.58 Shewana3_3082 putative glycerol-3-phosphate acyltransferase PlsY (RefSeq) low > 73
Shewanella oneidensis MR-1 0.56 SO3455 relA GTP pyrophosphokinase (NCBI ptt file) 0.59 SO1290 conserved hypothetical protein TIGR00023 (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.56 Shew_1202 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) 0.59 Shew_1001 putative glycerol-3-phosphate acyltransferase PlsY (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.53 MIT1002_00794 GTP pyrophosphokinase 0.58 MIT1002_00740 G3P acyltransferase low > 70
Pseudomonas sp. FW215-L2 0.45 GFF1678 GTP pyrophosphokinase 0.30 GFF46 putative glycerol-3-phosphate acyltransferase low > 111
Pseudomonas fluorescens GW456-L13 0.45 PfGW456L13_2035 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) 0.33 PfGW456L13_1190 Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.45 Psyr_3695 RelA/SpoT protein 0.35 Psyr_4637 acyl-phosphate glycerol-3-phosphate acyltransferase low > 86
Pseudomonas syringae pv. syringae B728a 0.45 Psyr_3695 RelA/SpoT protein 0.35 Psyr_4637 acyl-phosphate glycerol-3-phosphate acyltransferase low > 86
Pseudomonas fluorescens FW300-N2C3 0.45 AO356_19060 (p)ppGpp synthetase 0.33 AO356_14285 glycerol-3-phosphate acyltransferase low > 104
Pseudomonas sp. RS175 0.45 PFR28_03223 GTP pyrophosphokinase 0.33 PFR28_04074 Glycerol-3-phosphate acyltransferase low > 88
Pseudomonas lactucae CFBP13502 0.45 GEMAOFIL_04223 GTP pyrophosphokinase 0.32 GEMAOFIL_05292 Glycerol-3-phosphate acyltransferase low > 96
Pseudomonas orientalis W4I3 0.45 QF045_RS22260 GTP diphosphokinase 0.32 QF045_RS00260 glycerol-3-phosphate 1-O-acyltransferase PlsY low > 93
Pseudomonas fluorescens FW300-N2E2 0.45 Pf6N2E2_5723 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) 0.32 Pf6N2E2_4795 Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY low > 103
Pseudomonas fluorescens FW300-N2E3 0.45 AO353_02710 (p)ppGpp synthetase 0.33 AO353_07365 glycerol-3-phosphate acyltransferase low > 101
Pseudomonas fluorescens SBW25 0.45 PFLU_RS22095 GTP diphosphokinase 0.31 PFLU_RS27515 glycerol-3-phosphate 1-O-acyltransferase PlsY low > 109
Pseudomonas fluorescens SBW25-INTG 0.45 PFLU_RS22095 GTP diphosphokinase 0.31 PFLU_RS27515 glycerol-3-phosphate 1-O-acyltransferase PlsY low > 109
Pseudomonas protegens RBAN4 0.45 FABNJH_22975 relA GTP diphosphokinase 0.32 FABNJH_28495 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY
Pseudomonas fluorescens FW300-N1B4 0.45 Pf1N1B4_3508 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) 0.32 Pf1N1B4_2517 Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY low > 87
Pseudomonas simiae WCS417 0.45 PS417_20150 (p)ppGpp synthetase 0.32 PS417_25860 glycerol-3-phosphate acyltransferase
Pseudomonas sp. DMC3 0.45 GFF4818 GTP pyrophosphokinase 0.32 GFF47 Glycerol-3-phosphate acyltransferase low > 89
Pseudomonas putida KT2440 0.45 PP_1656 ATP:GTP 3'-pyrophosphotransferase 0.31 PP_0391 Glycerol-3-phosphate acyltransferase low > 96
Pseudomonas sp. BP01 0.45 JOY50_RS23910 relA GTP diphosphokinase 0.35 JOY50_RS18090 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY low > 84
Pseudomonas sp. SVBP6 0.45 COO64_RS07325 relA GTP diphosphokinase 0.33 COO64_RS22560 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY low > 91
Pseudomonas aeruginosa PUPa3 0.45 NPBIFN_04252 relA GTP diphosphokinase 0.32 NPBIFN_00595 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY low > 101
Pseudomonas aeruginosa MRSN321 0.45 PFGADD_04193 relA GTP diphosphokinase 0.32 PFGADD_00591 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY low > 99
Pseudomonas aeruginosa PA14 0.45 IKLFDK_04200 GTP diphosphokinase 0.32 IKLFDK_22505 glycerol-3-phosphate 1-O-acyltransferase PlsY low > 98
Pseudomonas sp. S08-1 0.45 OH686_18960 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase , (p)ppGpp synthetase I 0.26 OH686_14990 acyl-phosphate glycerol 3-phosphate acyltransferase low > 80
Pseudomonas stutzeri RCH2 0.44 Psest_1640 (p)ppGpp synthetase, RelA/SpoT family 0.31 Psest_3678 acyl-phosphate glycerol 3-phosphate acyltransferase low > 67
Pseudomonas segetis P6 0.44 ACVTMO_RS08195 relA GTP diphosphokinase 0.34 ACVTMO_RS04300 plsY glycerol-3-phosphate 1-O-acyltransferase PlsY 0.46 34
Marinobacter adhaerens HP15 0.43 HP15_791 (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA 0.32 HP15_319 predicted membrane protein 0.27 29
Kangiella aquimarina DSM 16071 0.43 B158DRAFT_2277 (p)ppGpp synthetase, RelA/SpoT family 0.44 B158DRAFT_0827 acyl-phosphate glycerol 3-phosphate acyltransferase low > 40
Ralstonia solanacearum GMI1000 0.38 RS_RS07930 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.40 RS_RS12765 glycerol-3-phosphate acyltransferase
Ralstonia sp. UNC404CL21Col 0.38 ABZR87_RS13745 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.41 ABZR87_RS00805 glycerol-3-phosphate 1-O-acyltransferase PlsY
Ralstonia solanacearum PSI07 0.38 RPSI07_RS15685 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.39 RPSI07_RS12150 glycerol-3-phosphate 1-O-acyltransferase PlsY
Dechlorosoma suillum PS 0.38 Dsui_2816 (p)ppGpp synthetase, RelA/SpoT family 0.26 Dsui_1214 acyl-phosphate glycerol 3-phosphate acyltransferase
Ralstonia solanacearum UW163 0.38 UW163_RS15115 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.40 UW163_RS08475 glycerol-3-phosphate 1-O-acyltransferase PlsY
Ralstonia solanacearum IBSBF1503 0.38 RALBFv3_RS01805 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.40 RALBFv3_RS05150 glycerol-3-phosphate 1-O-acyltransferase PlsY
Paraburkholderia sabiae LMG 24235 0.37 QEN71_RS05265 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.37 QEN71_RS02770 glycerol-3-phosphate 1-O-acyltransferase PlsY
Methylophilus sp. DMC18 0.37 GFF2658 GTP pyrophosphokinase 0.37 GFF2344 Glycerol-3-phosphate acyltransferase
Cupriavidus basilensis FW507-4G11 0.37 RR42_RS06585 GTP pyrophosphokinase 0.42 RR42_RS03335 glycerol-3-phosphate acyltransferase
Paraburkholderia graminis OAS925 0.35 ABIE53_002905 GTP pyrophosphokinase 0.34 ABIE53_003358 glycerol-3-phosphate acyltransferase PlsY
Paraburkholderia bryophila 376MFSha3.1 0.35 H281DRAFT_04499 GTP pyrophosphokinase 0.34 H281DRAFT_04123 acyl-phosphate glycerol-3-phosphate acyltransferase
Herbaspirillum seropedicae SmR1 0.35 HSERO_RS09855 GTP pyrophosphokinase 0.36 HSERO_RS04275 glycerol-3-phosphate acyltransferase
Collimonas humicola GW821-FHT01A05 0.35 MPMX01_03028 GTP pyrophosphokinase 0.34 MPMX01_04127 putative glycerol-3-phosphate acyltransferase
Burkholderia phytofirmans PsJN 0.35 BPHYT_RS13655 GTP pyrophosphokinase 0.34 BPHYT_RS15935 glycerol-3-phosphate acyltransferase
Acidovorax sp. GW101-3H11 0.34 Ac3H11_362 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I 0.42 Ac3H11_2623 Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY
Castellaniella sp019104865 MT123 0.34 ABCV34_RS08440 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.36 ABCV34_RS03025 glycerol-3-phosphate 1-O-acyltransferase PlsY
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF4925 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I 0.41 GFF289 Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY
Variovorax sp. SCN45 0.32 GFF403 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I 0.33 GFF3102 Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY (EC 2.3.1.n3)

Not shown: 9 genomes with orthologs for CSW01_12405 only; 15 genomes with orthologs for CSW01_02775 only