Conservation of cofitness between BWI76_RS20830 and BWI76_RS02095 in Klebsiella michiganensis M5al

69 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS20830 bifunctional malic enzyme oxidoreductase/phosphotransacetylase 1.0 BWI76_RS02095 acetyl-coenzyme A synthetase 0.22 9
Enterobacter sp. TBS_079 0.95 MPMX20_03324 NADP-dependent malic enzyme 0.95 MPMX20_00291 Acetyl-coenzyme A synthetase low > 85
Escherichia coli ECRC100 0.94 OKFHMN_22005 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.94 OKFHMN_12830 acs acetate--CoA ligase low > 80
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF2198 NADP-dependent malic enzyme (EC 1.1.1.40) 0.94 GFF1452 Acetyl-coenzyme A synthetase (EC 6.2.1.1) low > 78
Escherichia coli ECRC101 0.94 MCAODC_12535 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.94 MCAODC_03340 acs acetate--CoA ligase low > 87
Escherichia fergusonii Becca 0.94 EFB2_01425 NADP-dependent malic enzyme 0.94 EFB2_04520 Acetyl-coenzyme A synthetase low > 86
Escherichia coli ECOR38 0.94 HEPCGN_21175 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.94 HEPCGN_11455 acs acetate--CoA ligase low > 87
Escherichia coli ECRC98 0.94 JDDGAC_25950 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.94 JDDGAC_16465 acs acetate--CoA ligase low > 86
Escherichia coli ECRC102 0.94 NIAGMN_19775 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.94 NIAGMN_10675 acs acetate--CoA ligase — —
Escherichia coli Nissle 1917 0.94 ECOLIN_RS14055 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.94 ECOLIN_RS23550 acetate--CoA ligase 0.31 49
Escherichia coli ECOR27 0.94 NOLOHH_13685 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.94 NOLOHH_05080 acs acetate--CoA ligase low > 75
Escherichia coli ECRC62 0.94 BNILDI_12495 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.94 BNILDI_06445 acs acetate--CoA ligase low > 75
Escherichia coli BW25113 0.94 b2463 maeB malic enzyme (NCBI) 0.94 b4069 acs acetyl-coenzyme A synthetase (NCBI) 0.44 5
Escherichia coli HS(pFamp)R (ATCC 700891) 0.94 OHPLBJKB_01268 NADP-dependent malic enzyme 0.94 OHPLBJKB_03971 Acetyl-coenzyme A synthetase low > 73
Enterobacter asburiae PDN3 0.94 EX28DRAFT_0198 Malic enzyme 0.95 EX28DRAFT_4232 acetate--CoA ligase 0.48 15
Escherichia coli ECRC99 0.94 KEDOAH_06215 maeB NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.94 KEDOAH_15320 acs acetate--CoA ligase — —
Escherichia coli BL21 0.94 ECD_02354 malic enzyme: putative oxidoreductase/phosphotransacetylase 0.94 ECD_03941 acetyl-CoA synthetase low > 61
Pectobacterium carotovorum WPP14 0.88 HER17_RS17280 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.86 HER17_RS17630 acetate--CoA ligase low > 75
Serratia liquefaciens MT49 0.87 IAI46_18585 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.87 IAI46_01405 acetate--CoA ligase low > 86
Rahnella sp. WP5 0.86 EX31_RS20275 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.87 EX31_RS09040 acetate--CoA ligase low > 89
Dickeya dadantii 3937 0.86 DDA3937_RS04355 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.85 DDA3937_RS03480 acetate--CoA ligase low > 74
Dickeya dianthicola 67-19 0.85 HGI48_RS04345 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.84 HGI48_RS03580 acetate--CoA ligase low > 71
Dickeya dianthicola ME23 0.85 DZA65_RS04265 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase 0.84 DZA65_RS03695 acetate--CoA ligase low > 75
Dechlorosoma suillum PS 0.63 Dsui_0543 malic enzyme 0.47 Dsui_2003 acetate--CoA ligase low > 51
Burkholderia phytofirmans PsJN 0.63 BPHYT_RS18310 malic enzyme 0.47 BPHYT_RS07000 acetyl-CoA synthetase low > 109
Paraburkholderia graminis OAS925 0.63 ABIE53_000015 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) 0.47 ABIE53_001664 acetyl-CoA synthetase low > 113
Paraburkholderia sabiae LMG 24235 0.63 QEN71_RS28455 NADP-dependent malic enzyme 0.47 QEN71_RS23765 acetate--CoA ligase low > 153
Paraburkholderia bryophila 376MFSha3.1 0.63 H281DRAFT_05846 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) 0.47 H281DRAFT_04953 acetyl-coenzyme A synthetase low > 103
Herbaspirillum seropedicae SmR1 0.63 HSERO_RS16825 NADP-dependent malic enzyme oxidoreductase 0.46 HSERO_RS07770 acetyl-CoA synthetase low > 78
Ralstonia solanacearum IBSBF1503 0.62 RALBFv3_RS03260 NADP-dependent malic enzyme 0.46 RALBFv3_RS02445 acetate--CoA ligase low > 76
Ralstonia solanacearum UW163 0.62 UW163_RS10465 NADP-dependent malic enzyme 0.46 UW163_RS11280 acetate--CoA ligase — —
Cupriavidus basilensis FW507-4G11 0.62 RR42_RS05210 malic enzyme 0.48 RR42_RS13880 AMP-dependent synthetase low > 128
Acinetobacter radioresistens SK82 0.62 MPMX26_01000 NADP-dependent malic enzyme 0.64 MPMX26_02906 Acetyl-coenzyme A synthetase 0.74 12
Ralstonia solanacearum GMI1000 0.62 RS_RS10650 NADP-dependent malic enzyme 0.46 RS_RS09815 acetyl-coenzyme A synthetase low > 80
Ralstonia solanacearum PSI07 0.62 RPSI07_RS14050 NADP-dependent malic enzyme 0.46 RPSI07_RS14880 acetate--CoA ligase low > 81
Variovorax sp. OAS795 0.61 ABID97_RS22340 NADP-dependent malic enzyme 0.46 ABID97_RS27430 acetate--CoA ligase low > 91
Ralstonia sp. UNC404CL21Col 0.61 ABZR87_RS15110 NADP-dependent malic enzyme 0.46 ABZR87_RS14360 acetate--CoA ligase low > 80
Variovorax sp. SCN45 0.61 GFF1796 NADP-dependent malic enzyme (EC 1.1.1.40) 0.46 GFF475 Acetyl-CoA synthetase (EC 6.2.1.1) low > 127
Lysobacter sp. OAE881 0.60 ABIE51_RS18820 NADP-dependent malic enzyme 0.64 ABIE51_RS01660 acetate--CoA ligase low > 62
Hydrogenophaga sp. GW460-11-11-14-LB1 0.60 GFF3306 NADP-dependent malic enzyme (EC 1.1.1.40) 0.46 GFF4107 Acetyl-coenzyme A synthetase (EC 6.2.1.1) 0.49 41
Azospirillum sp. SherDot2 0.60 MPMX19_04254 NADP-dependent malic enzyme 0.66 MPMX19_02038 Acetyl-coenzyme A synthetase low > 112
Magnetospirillum magneticum AMB-1 0.60 AMB_RS03695 NADP-dependent malic enzyme 0.70 AMB_RS21140 acetate--CoA ligase low > 64
Castellaniella sp019104865 MT123 0.60 ABCV34_RS01715 NADP-dependent malic enzyme 0.48 ABCV34_RS00680 acetate--CoA ligase low > 48
Acidovorax sp. GW101-3H11 0.59 Ac3H11_1079 NADP-dependent malic enzyme (EC 1.1.1.40) 0.46 Ac3H11_951 Acetyl-coenzyme A synthetase (EC 6.2.1.1) low > 79
Dyella japonica UNC79MFTsu3.2 0.59 ABZR86_RS12415 NADP-dependent malic enzyme 0.66 ABZR86_RS15200 acetate--CoA ligase low > 74
Rhodanobacter denitrificans MT42 0.59 LRK55_RS10875 NADP-dependent malic enzyme 0.65 LRK55_RS08185 acetate--CoA ligase — —
Rhodanobacter denitrificans FW104-10B01 0.59 LRK54_RS11170 NADP-dependent malic enzyme 0.65 LRK54_RS08420 acetate--CoA ligase low > 59
Rhodanobacter sp. FW510-T8 0.59 OKGIIK_12705 pta NADP-dependent malic enzyme 0.64 OKGIIK_15190 acs acetate--CoA ligase low > 52
Xanthomonas campestris pv. campestris strain 8004 0.58 Xcc-8004.1035.1 NADP-dependent malic enzyme (EC 1.1.1.40) 0.64 Xcc-8004.5157.1 Acetyl-coenzyme A synthetase (EC 6.2.1.1) — —
Caulobacter crescentus NA1000 Δfur 0.58 CCNA_02704 NADP-dependent malic enzyme 0.61 CCNA_03696 acetyl-coenzyme A synthetase low > 67
Caulobacter crescentus NA1000 0.58 CCNA_02704 NADP-dependent malic enzyme 0.61 CCNA_03696 acetyl-coenzyme A synthetase — —
Azospirillum brasilense Sp245 0.57 AZOBR_RS21145 NADP-dependent malic enzyme 0.68 AZOBR_RS00270 acetyl-CoA synthetase low > 97
Sinorhizobium meliloti 1021 0.56 SMc00169 malic enzyme 0.64 SMc04093 acetyl-CoA synthetase low > 103
Rhizobium sp. OAE497 0.56 ABIE40_RS10450 NADP-dependent malic enzyme 0.65 ABIE40_RS19160 acetate--CoA ligase low > 107
Agrobacterium fabrum C58 0.55 Atu1652 NADP-dependent malic enzyme 0.64 Atu2745 acetyl-coenzyme A synthetase — —
Phaeobacter inhibens DSM 17395 0.54 PGA1_c11910 Malate dehydrogenase (decarboxylating) (EC 1.1.1.39) (from data) 0.60 PGA1_c12950 acetyl-coenzyme A synthetase Acs low > 62
Bosea sp. OAE506 0.53 ABIE41_RS21715 NADP-dependent malic enzyme 0.67 ABIE41_RS05675 acetate--CoA ligase low > 77
Dinoroseobacter shibae DFL-12 0.52 Dshi_0826 malic protein NAD-binding (RefSeq) 0.63 Dshi_1399 acetate--CoA ligase (RefSeq) — —
Rhodopseudomonas palustris CGA009 0.51 TX73_015740 NADP-dependent malic enzyme 0.68 TX73_001095 acetate--CoA ligase low > 86
Echinicola vietnamensis KMM 6221, DSM 17526 0.47 Echvi_4081 Malic enzyme 0.52 Echvi_1268 acetate--CoA ligase low > 79
Pedobacter sp. GW460-11-11-14-LB5 0.46 CA265_RS19000 NADP-dependent malic enzyme 0.54 CA265_RS16340 acetate--CoA ligase low > 88
Phocaeicola vulgatus CL09T03C04 0.46 HMPREF1058_RS02110 NADP-dependent malic enzyme 0.15 HMPREF1058_RS08765 AMP-binding protein low > 67
Bacteroides stercoris CC31F 0.45 HMPREF1181_RS07830 NADP-dependent malic enzyme 0.15 HMPREF1181_RS03430 AMP-binding protein 0.57 40
Bacteroides thetaiotaomicron VPI-5482 0.45 BT1969 NADP-dependent malate dehydrogenase (NCBI ptt file) 0.16 BT3755 acetyl-coenzyme A synthetase (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.45 BACOVA_00097 phosphate acetyl/butyryl transferase 0.15 BACOVA_03585 AMP-binding enzyme low > 94
Mucilaginibacter yixingensis YX-36 DSM 26809 0.45 ABZR88_RS18305 NADP-dependent malic enzyme 0.52 ABZR88_RS15400 acetate--CoA ligase low > 71
Parabacteroides merdae CL09T00C40 0.44 HMPREF1078_RS07665 NADP-dependent malic enzyme 0.15 HMPREF1078_RS10645 AMP-binding protein low > 61
Rhodospirillum rubrum S1H 0.43 Rru_A3542 malate dehydrogenase (NCBI) 0.67 Rru_A3575 Acetate--CoA ligase (NCBI) 0.50 36
Sphingomonas koreensis DSMZ 15582 0.42 Ga0059261_3786 Malic enzyme 0.62 Ga0059261_1313 acetyl-coenzyme A synthetase (EC 6.2.1.1) low > 68
Brevundimonas sp. GW460-12-10-14-LB2 0.40 A4249_RS13295 NADP-dependent malic enzyme 0.62 A4249_RS15190 acetate--CoA ligase — —

Not shown: 2 genomes with orthologs for BWI76_RS20830 only; 30 genomes with orthologs for BWI76_RS02095 only