Conservation of cofitness between BWI76_RS04670 and BWI76_RS00980 in Klebsiella michiganensis M5al

69 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS04670 3-isopropylmalate dehydratase large subunit 1.0 BWI76_RS00980 PLP-dependent threonine dehydratase 0.95 4
Escherichia coli Nissle 1917 0.95 ECOLIN_RS00390 3-isopropylmalate dehydratase large subunit 0.94 ECOLIN_RS21670 threonine ammonia-lyase, biosynthetic low > 55
Escherichia coli BW25113 0.95 b0072 leuC isopropylmalate isomerase large subunit (NCBI) 0.94 b3772 ilvA threonine dehydratase (NCBI) 0.97 7
Escherichia coli ECOR38 0.95 HEPCGN_08705 leuC1 3-isopropylmalate dehydratase large subunit 1 0.95 HEPCGN_13345 ilvA threonine ammonia-lyase, biosynthetic 0.94 50
Escherichia coli ECOR27 0.95 NOLOHH_03070 leuC1 3-isopropylmalate dehydratase large subunit 1 0.95 NOLOHH_06770 ilvA threonine ammonia-lyase, biosynthetic 0.93 35
Escherichia coli ECRC62 0.95 BNILDI_08540 leuC1 3-isopropylmalate dehydratase large subunit 1 0.95 BNILDI_04755 ilvA threonine ammonia-lyase, biosynthetic 0.98 24
Escherichia coli BL21 0.95 ECD_00074 3-isopropylmalate dehydratase large subunit 0.94 ECD_03650 l-threonine dehydratase, biosynthetic; also known as threonine deaminase 0.93 19
Escherichia coli HS(pFamp)R (ATCC 700891) 0.95 OHPLBJKB_03585 3-isopropylmalate dehydratase large subunit 0.94 OHPLBJKB_04281 L-threonine dehydratase biosynthetic IlvA low > 73
Escherichia fergusonii Becca 0.95 EFB2_03973 3-isopropylmalate dehydratase large subunit 0.94 EFB2_04864 L-threonine dehydratase biosynthetic IlvA low > 86
Enterobacter asburiae PDN3 0.95 EX28DRAFT_3668 3-isopropylmalate dehydratase, large subunit 0.94 EX28DRAFT_4444 threonine ammonia-lyase, biosynthetic, long form 0.96 5
Escherichia coli ECRC101 0.95 MCAODC_01240 leuC1 3-isopropylmalate dehydratase large subunit 1 0.95 MCAODC_05140 ilvA threonine ammonia-lyase, biosynthetic 0.96 14
Escherichia coli ECRC98 0.95 JDDGAC_14320 leuC1 3-isopropylmalate dehydratase large subunit 1 0.95 JDDGAC_18255 ilvA threonine ammonia-lyase, biosynthetic 0.97 12
Escherichia coli ECRC99 0.95 KEDOAH_17430 leuC1 3-isopropylmalate dehydratase large subunit 1 0.95 KEDOAH_13515 ilvA threonine ammonia-lyase, biosynthetic
Escherichia coli ECRC102 0.95 NIAGMN_08575 leuC1 3-isopropylmalate dehydratase large subunit 1 0.95 NIAGMN_12390 ilvA threonine ammonia-lyase, biosynthetic
Escherichia coli ECRC100 0.95 OKFHMN_10725 leuC1 3-isopropylmalate dehydratase large subunit 1 0.95 OKFHMN_14635 ilvA threonine ammonia-lyase, biosynthetic 0.97 26
Enterobacter sp. TBS_079 0.95 MPMX20_00767 3-isopropylmalate dehydratase large subunit 1 0.94 MPMX20_04498 L-threonine dehydratase biosynthetic IlvA 0.95 4
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF166 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.94 GFF2900 Threonine dehydratase biosynthetic (EC 4.3.1.19) low > 78
Rahnella sp. WP5 0.87 EX31_RS03690 3-isopropylmalate dehydratase large subunit 0.82 EX31_RS15010 threonine ammonia-lyase, biosynthetic 0.93 53
Pantoea sp. MT58 0.86 IAI47_16010 3-isopropylmalate dehydratase large subunit 0.84 IAI47_01040 threonine ammonia-lyase, biosynthetic 0.98 12
Serratia liquefaciens MT49 0.85 IAI46_03345 3-isopropylmalate dehydratase large subunit 0.84 IAI46_24340 threonine ammonia-lyase, biosynthetic 0.61 48
Dickeya dadantii 3937 0.85 DDA3937_RS18125 3-isopropylmalate dehydratase large subunit 0.86 DDA3937_RS20150 threonine ammonia-lyase, biosynthetic 0.75 17
Pectobacterium carotovorum WPP14 0.85 HER17_RS03075 3-isopropylmalate dehydratase large subunit 0.84 HER17_RS01080 threonine ammonia-lyase, biosynthetic 0.95 35
Dickeya dianthicola 67-19 0.85 HGI48_RS18065 3-isopropylmalate dehydratase large subunit 0.87 HGI48_RS20290 threonine ammonia-lyase, biosynthetic low > 71
Dickeya dianthicola ME23 0.85 DZA65_RS19210 3-isopropylmalate dehydratase large subunit 0.84 DZA65_RS21330 threonine ammonia-lyase, biosynthetic 0.84 12
Erwinia tracheiphila SCR3 0.79 LU632_RS02870 leuC 3-isopropylmalate dehydratase large subunit 0.84 LU632_RS24395 ilvA threonine ammonia-lyase, biosynthetic 0.66 50
Vibrio cholerae E7946 ATCC 55056 0.79 CSW01_12605 3-isopropylmalate dehydratase large subunit 0.68 CSW01_00135 threonine ammonia-lyase, biosynthetic low > 62
Shewanella oneidensis MR-1 0.73 SO4234 leuC 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) 0.58 SO4344 ilvA threonine dehydratase (NCBI ptt file) 0.87 68
Shewanella sp. ANA-3 0.73 Shewana3_3759 isopropylmalate isomerase large subunit (RefSeq) 0.56 Shewana3_0359 threonine dehydratase (RefSeq) 0.87 63
Shewanella amazonensis SB2B 0.72 Sama_0337 isopropylmalate isomerase large subunit (RefSeq) 0.58 Sama_3278 threonine dehydratase (RefSeq) 0.94 20
Shewanella loihica PV-4 0.71 Shew_3470 isopropylmalate isomerase large subunit (RefSeq) 0.55 Shew_0293 threonine dehydratase (RefSeq) 0.98 14
Alteromonas macleodii MIT1002 0.68 MIT1002_00947 3-isopropylmalate dehydratase large subunit 0.54 MIT1002_04040 L-threonine dehydratase biosynthetic IlvA 0.98 24
Azospirillum sp. SherDot2 0.68 MPMX19_01998 3-isopropylmalate dehydratase large subunit 0.51 MPMX19_02807 L-threonine dehydratase biosynthetic IlvA low > 112
Cupriavidus basilensis FW507-4G11 0.63 RR42_RS14400 isopropylmalate isomerase 0.46 RR42_RS02315 threonine dehydratase low > 128
Pseudomonas stutzeri RCH2 0.63 Psest_2591 3-isopropylmalate dehydratase, large subunit 0.50 Psest_3866 threonine ammonia-lyase, biosynthetic, long form 0.92 5
Ralstonia sp. UNC404CL21Col 0.62 ABZR87_RS14540 3-isopropylmalate dehydratase large subunit 0.47 ABZR87_RS07360 threonine ammonia-lyase, biosynthetic 0.91 3
Ralstonia solanacearum PSI07 0.62 RPSI07_RS14695 3-isopropylmalate dehydratase large subunit 0.50 RPSI07_RS21810 threonine ammonia-lyase, biosynthetic 0.81 4
Burkholderia phytofirmans PsJN 0.62 BPHYT_RS33915 isopropylmalate isomerase 0.50 BPHYT_RS11065 threonine dehydratase
Pseudomonas sp. S08-1 0.62 OH686_04480 3-isopropylmalate dehydratase large subunit 0.51 OH686_11400 threonine ammonia-lyase, biosynthetic 0.87 9
Ralstonia solanacearum GMI1000 0.62 RS_RS10000 3-isopropylmalate dehydratase large subunit 0.50 RS_RS02225 threonine ammonia-lyase, biosynthetic
Pseudomonas syringae pv. syringae B728a 0.62 Psyr_1983 3-isopropylmalate dehydratase, large subunit 0.49 Psyr_4846 L-threonine ammonia-lyase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.62 Psyr_1983 3-isopropylmalate dehydratase, large subunit 0.49 Psyr_4846 L-threonine ammonia-lyase low > 86
Paraburkholderia sabiae LMG 24235 0.62 QEN71_RS17605 3-isopropylmalate dehydratase large subunit 0.50 QEN71_RS01985 threonine ammonia-lyase, biosynthetic 0.85 12
Castellaniella sp019104865 MT123 0.62 ABCV34_RS04290 3-isopropylmalate dehydratase large subunit 0.51 ABCV34_RS14460 threonine ammonia-lyase, biosynthetic 0.64 5
Phaeobacter inhibens DSM 17395 0.62 PGA1_c29780 3-isopropylmalate dehydratase large subunit 0.18 PGA1_c34900 threonine dehydratase biosynthetic low > 62
Ralstonia solanacearum IBSBF1503 0.62 RALBFv3_RS02620 3-isopropylmalate dehydratase large subunit 0.48 RALBFv3_RS11395 threonine ammonia-lyase, biosynthetic low > 76
Ralstonia solanacearum UW163 0.62 UW163_RS11105 3-isopropylmalate dehydratase large subunit 0.48 UW163_RS02190 threonine ammonia-lyase, biosynthetic
Pseudomonas putida KT2440 0.61 PP_1985 3-isopropylmalate dehydratase large subunit 0.51 PP_3446 threonine deaminase low > 96
Acinetobacter radioresistens SK82 0.61 MPMX26_00345 3-isopropylmalate dehydratase large subunit 0.47 MPMX26_01278 L-threonine dehydratase biosynthetic IlvA 0.96 7
Pseudomonas sp. RS175 0.61 PFR28_02824 3-isopropylmalate dehydratase large subunit 0.49 PFR28_04834 L-threonine dehydratase biosynthetic IlvA 0.42 35
Paraburkholderia graminis OAS925 0.61 ABIE53_004801 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit 0.49 ABIE53_002293 threonine dehydratase low > 113
Pseudomonas fluorescens FW300-N1B4 0.61 Pf1N1B4_15 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.49 Pf1N1B4_2280 Threonine dehydratase biosynthetic (EC 4.3.1.19) 0.80 35
Pseudomonas fluorescens FW300-N2C3 0.61 AO356_21400 isopropylmalate isomerase 0.49 AO356_10330 threonine dehydratase 0.73 44
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS20580 3-isopropylmalate dehydratase large subunit 0.48 PFLU_RS28665 threonine ammonia-lyase, biosynthetic low > 109
Pseudomonas fluorescens SBW25 0.61 PFLU_RS20580 3-isopropylmalate dehydratase large subunit 0.48 PFLU_RS28665 threonine ammonia-lyase, biosynthetic low > 109
Marinobacter adhaerens HP15 0.61 HP15_1834 protein containing 3-isopropylmalate dehydratase, large subunit region domain 0.54 HP15_3213 threonine dehydratase biosynthetic 0.95 3
Pseudomonas fluorescens FW300-N2E2 0.61 Pf6N2E2_63 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.49 Pf6N2E2_3938 Threonine dehydratase biosynthetic (EC 4.3.1.19) 0.47 56
Pseudomonas simiae WCS417 0.60 PS417_18600 isopropylmalate isomerase 0.49 PS417_27010 threonine dehydratase 0.73 35
Herbaspirillum seropedicae SmR1 0.60 HSERO_RS16515 isopropylmalate isomerase 0.47 HSERO_RS19510 threonine dehydratase 0.94 9
Pseudomonas fluorescens GW456-L13 0.60 PfGW456L13_3948 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.49 PfGW456L13_949 Threonine dehydratase biosynthetic (EC 4.3.1.19) 0.76 56
Pseudomonas fluorescens FW300-N2E3 0.60 AO353_20620 isopropylmalate isomerase 0.50 AO353_08485 threonine dehydratase 0.72 48
Variovorax sp. OAS795 0.59 ABID97_RS08465 3-isopropylmalate dehydratase large subunit 0.49 ABID97_RS07000 threonine ammonia-lyase, biosynthetic
Hydrogenophaga sp. GW460-11-11-14-LB1 0.59 GFF3363 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.51 GFF1379 Threonine dehydratase biosynthetic (EC 4.3.1.19) 0.85 6
Variovorax sp. SCN45 0.59 GFF3890 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.50 GFF5246 Threonine dehydratase biosynthetic (EC 4.3.1.19) low > 127
Dechlorosoma suillum PS 0.59 Dsui_3201 3-isopropylmalate dehydratase, large subunit 0.50 Dsui_0728 threonine ammonia-lyase, biosynthetic, long form
Acidovorax sp. GW101-3H11 0.58 Ac3H11_1525 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.50 Ac3H11_2042 Threonine dehydratase biosynthetic (EC 4.3.1.19) 0.63 57
Rhodanobacter denitrificans FW104-10B01 0.54 LRK54_RS07375 3-isopropylmalate dehydratase large subunit 0.45 LRK54_RS10300 threonine ammonia-lyase, biosynthetic low > 59
Rhodanobacter denitrificans MT42 0.54 LRK55_RS07105 3-isopropylmalate dehydratase large subunit 0.45 LRK55_RS09940 threonine ammonia-lyase, biosynthetic low > 63
Brevundimonas sp. GW460-12-10-14-LB2 0.52 A4249_RS10005 3-isopropylmalate dehydratase large subunit 0.49 A4249_RS00615 threonine ammonia-lyase, biosynthetic 0.99 25
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS15960 3-isopropylmalate dehydratase large subunit 0.49 ABZR86_RS15925 threonine ammonia-lyase, biosynthetic low > 74
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_13585 leuC 3-isopropylmalate dehydratase large subunit 0.46 OKGIIK_13620 ilvA threonine ammonia-lyase, biosynthetic low > 52

Not shown: 33 genomes with orthologs for BWI76_RS04670 only; 0 genomes with orthologs for BWI76_RS00980 only