Conservation of cofitness between BWI76_RS00805 and BWI76_RS00980 in Klebsiella michiganensis M5al

69 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS00805 5,10-methylenetetrahydrofolate reductase 1.0 BWI76_RS00980 PLP-dependent threonine dehydratase 0.92 3
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF2329 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.94 GFF2900 Threonine dehydratase biosynthetic (EC 4.3.1.19) low > 78
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4413 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.94 EX28DRAFT_4444 threonine ammonia-lyase, biosynthetic, long form low > 76
Escherichia coli BW25113 0.95 b3941 metF 5,10-methylenetetrahydrofolate reductase (NCBI) 0.94 b3772 ilvA threonine dehydratase (NCBI) 0.94 23
Escherichia coli BL21 0.95 ECD_03827 5,10-methylenetetrahydrofolate reductase 0.94 ECD_03650 l-threonine dehydratase, biosynthetic; also known as threonine deaminase 0.95 13
Enterobacter sp. TBS_079 0.95 MPMX20_04529 5,10-methylenetetrahydrofolate reductase 0.94 MPMX20_04498 L-threonine dehydratase biosynthetic IlvA 0.76 3
Escherichia coli HS(pFamp)R (ATCC 700891) 0.95 OHPLBJKB_04109 5,10-methylenetetrahydrofolate reductase 0.94 OHPLBJKB_04281 L-threonine dehydratase biosynthetic IlvA low > 73
Escherichia coli ECRC62 0.95 BNILDI_05725 metF methylenetetrahydrofolate reductase 0.95 BNILDI_04755 ilvA threonine ammonia-lyase, biosynthetic 0.98 14
Escherichia coli ECOR27 0.95 NOLOHH_05810 metF methylenetetrahydrofolate reductase 0.95 NOLOHH_06770 ilvA threonine ammonia-lyase, biosynthetic 0.94 32
Escherichia coli ECOR38 0.95 HEPCGN_12310 metF methylenetetrahydrofolate reductase 0.95 HEPCGN_13345 ilvA threonine ammonia-lyase, biosynthetic 0.90 51
Escherichia coli ECRC102 0.95 NIAGMN_11420 metF methylenetetrahydrofolate reductase 0.95 NIAGMN_12390 ilvA threonine ammonia-lyase, biosynthetic
Escherichia coli ECRC99 0.95 KEDOAH_14495 metF methylenetetrahydrofolate reductase 0.95 KEDOAH_13515 ilvA threonine ammonia-lyase, biosynthetic
Escherichia coli ECRC101 0.95 MCAODC_04165 metF methylenetetrahydrofolate reductase 0.95 MCAODC_05140 ilvA threonine ammonia-lyase, biosynthetic 0.97 10
Escherichia coli ECRC98 0.95 JDDGAC_17290 metF methylenetetrahydrofolate reductase 0.95 JDDGAC_18255 ilvA threonine ammonia-lyase, biosynthetic 0.99 4
Escherichia coli ECRC100 0.95 OKFHMN_13665 metF methylenetetrahydrofolate reductase 0.95 OKFHMN_14635 ilvA threonine ammonia-lyase, biosynthetic 0.98 22
Escherichia fergusonii Becca 0.94 EFB2_04672 5,10-methylenetetrahydrofolate reductase 0.94 EFB2_04864 L-threonine dehydratase biosynthetic IlvA low > 86
Escherichia coli Nissle 1917 0.94 ECOLIN_RS22760 methylenetetrahydrofolate reductase 0.94 ECOLIN_RS21670 threonine ammonia-lyase, biosynthetic low > 55
Pantoea sp. MT58 0.92 IAI47_00890 methylenetetrahydrofolate reductase 0.84 IAI47_01040 threonine ammonia-lyase, biosynthetic 0.47 47
Serratia liquefaciens MT49 0.92 IAI46_24530 methylenetetrahydrofolate reductase 0.84 IAI46_24340 threonine ammonia-lyase, biosynthetic low > 86
Dickeya dadantii 3937 0.91 DDA3937_RS00960 methylenetetrahydrofolate reductase 0.86 DDA3937_RS20150 threonine ammonia-lyase, biosynthetic low > 74
Rahnella sp. WP5 0.91 EX31_RS14205 methylenetetrahydrofolate reductase 0.82 EX31_RS15010 threonine ammonia-lyase, biosynthetic 0.89 46
Pectobacterium carotovorum WPP14 0.90 HER17_RS00950 methylenetetrahydrofolate reductase 0.84 HER17_RS01080 threonine ammonia-lyase, biosynthetic low > 75
Dickeya dianthicola 67-19 0.90 HGI48_RS20415 methylenetetrahydrofolate reductase 0.87 HGI48_RS20290 threonine ammonia-lyase, biosynthetic 0.65 2
Dickeya dianthicola ME23 0.90 DZA65_RS21460 methylenetetrahydrofolate reductase 0.84 DZA65_RS21330 threonine ammonia-lyase, biosynthetic 0.77 6
Erwinia tracheiphila SCR3 0.87 LU632_RS19630 metF methylenetetrahydrofolate reductase 0.84 LU632_RS24395 ilvA threonine ammonia-lyase, biosynthetic low > 74
Vibrio cholerae E7946 ATCC 55056 0.78 CSW01_13560 methylenetetrahydrofolate reductase 0.68 CSW01_00135 threonine ammonia-lyase, biosynthetic low > 62
Shewanella oneidensis MR-1 0.76 SO4054 metF 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.58 SO4344 ilvA threonine dehydratase (NCBI ptt file) 0.88 58
Shewanella amazonensis SB2B 0.76 Sama_3169 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.58 Sama_3278 threonine dehydratase (RefSeq) 0.93 46
Shewanella sp. ANA-3 0.76 Shewana3_3612 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.56 Shewana3_0359 threonine dehydratase (RefSeq) 0.87 66
Shewanella loihica PV-4 0.75 Shew_0522 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.55 Shew_0293 threonine dehydratase (RefSeq) 0.98 12
Alteromonas macleodii MIT1002 0.70 MIT1002_03670 5,10-methylenetetrahydrofolate reductase 0.54 MIT1002_04040 L-threonine dehydratase biosynthetic IlvA low > 70
Azospirillum sp. SherDot2 0.55 MPMX19_00635 5,10-methylenetetrahydrofolate reductase 0.51 MPMX19_02807 L-threonine dehydratase biosynthetic IlvA low > 112
Brevundimonas sp. GW460-12-10-14-LB2 0.46 A4249_RS07925 methylenetetrahydrofolate reductase [NAD(P)H] 0.49 A4249_RS00615 threonine ammonia-lyase, biosynthetic 0.99 27
Paraburkholderia sabiae LMG 24235 0.41 QEN71_RS28715 methylenetetrahydrofolate reductase [NAD(P)H] 0.50 QEN71_RS01985 threonine ammonia-lyase, biosynthetic 0.93 5
Paraburkholderia graminis OAS925 0.40 ABIE53_000061 methylenetetrahydrofolate reductase (NADPH) 0.49 ABIE53_002293 threonine dehydratase low > 113
Phaeobacter inhibens DSM 17395 0.40 PGA1_c11700 5,10-methylenetetrahydrofolate reductase MetF 0.18 PGA1_c34900 threonine dehydratase biosynthetic low > 62
Cupriavidus basilensis FW507-4G11 0.39 RR42_RS01385 5,10-methylenetetrahydrofolate reductase 0.46 RR42_RS02315 threonine dehydratase low > 128
Burkholderia phytofirmans PsJN 0.39 BPHYT_RS18705 5,10-methylenetetrahydrofolate reductase 0.50 BPHYT_RS11065 threonine dehydratase
Dechlorosoma suillum PS 0.39 Dsui_0640 5,10-methylenetetrahydrofolate reductase 0.50 Dsui_0728 threonine ammonia-lyase, biosynthetic, long form
Ralstonia solanacearum GMI1000 0.38 RS_RS00460 methylenetetrahydrofolate reductase [NAD(P)H] 0.50 RS_RS02225 threonine ammonia-lyase, biosynthetic
Ralstonia solanacearum PSI07 0.38 RPSI07_RS23495 methylenetetrahydrofolate reductase [NAD(P)H] 0.50 RPSI07_RS21810 threonine ammonia-lyase, biosynthetic 0.74 8
Ralstonia sp. UNC404CL21Col 0.38 ABZR87_RS04865 methylenetetrahydrofolate reductase [NAD(P)H] 0.47 ABZR87_RS07360 threonine ammonia-lyase, biosynthetic 0.75 15
Ralstonia solanacearum IBSBF1503 0.38 RALBFv3_RS09875 methylenetetrahydrofolate reductase [NAD(P)H] 0.48 RALBFv3_RS11395 threonine ammonia-lyase, biosynthetic 0.57 36
Ralstonia solanacearum UW163 0.38 UW163_RS03705 methylenetetrahydrofolate reductase [NAD(P)H] 0.48 UW163_RS02190 threonine ammonia-lyase, biosynthetic
Pseudomonas sp. RS175 0.38 PFR28_04202 5,10-methylenetetrahydrofolate reductase 0.49 PFR28_04834 L-threonine dehydratase biosynthetic IlvA low > 88
Pseudomonas sp. S08-1 0.37 OH686_10820 methylenetetrahydrofolate reductase [NAD(P)H] 0.51 OH686_11400 threonine ammonia-lyase, biosynthetic 0.81 7
Pseudomonas simiae WCS417 0.37 PS417_26510 5,10-methylenetetrahydrofolate reductase 0.49 PS417_27010 threonine dehydratase 0.45 11
Marinobacter adhaerens HP15 0.37 HP15_2917 5,10-methylenetetrahydrofolate reductase-like protein 0.54 HP15_3213 threonine dehydratase biosynthetic 0.97 2
Pseudomonas fluorescens FW300-N2E2 0.37 Pf6N2E2_4638 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.49 Pf6N2E2_3938 Threonine dehydratase biosynthetic (EC 4.3.1.19) low > 103
Pseudomonas fluorescens SBW25 0.37 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H] 0.48 PFLU_RS28665 threonine ammonia-lyase, biosynthetic low > 109
Pseudomonas fluorescens FW300-N1B4 0.37 Pf1N1B4_2384 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.49 Pf1N1B4_2280 Threonine dehydratase biosynthetic (EC 4.3.1.19) 0.69 49
Pseudomonas fluorescens SBW25-INTG 0.37 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H] 0.48 PFLU_RS28665 threonine ammonia-lyase, biosynthetic 0.21 101
Rhodanobacter denitrificans MT42 0.37 LRK55_RS11765 methylenetetrahydrofolate reductase [NAD(P)H] 0.45 LRK55_RS09940 threonine ammonia-lyase, biosynthetic low > 63
Rhodanobacter denitrificans FW104-10B01 0.37 LRK54_RS12030 methylenetetrahydrofolate reductase [NAD(P)H] 0.45 LRK54_RS10300 threonine ammonia-lyase, biosynthetic low > 59
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_08015 5,10-methylenetetrahydrofolate reductase 0.50 AO353_08485 threonine dehydratase 0.62 58
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_13605 5,10-methylenetetrahydrofolate reductase 0.49 AO356_10330 threonine dehydratase 0.73 46
Rhodanobacter sp. FW510-T8 0.36 OKGIIK_11830 metF methylenetetrahydrofolate reductase [NAD(P)H] 0.46 OKGIIK_13620 ilvA threonine ammonia-lyase, biosynthetic low > 52
Herbaspirillum seropedicae SmR1 0.36 HSERO_RS21425 5,10-methylenetetrahydrofolate reductase 0.47 HSERO_RS19510 threonine dehydratase low > 78
Pseudomonas fluorescens GW456-L13 0.36 PfGW456L13_1050 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.49 PfGW456L13_949 Threonine dehydratase biosynthetic (EC 4.3.1.19) 0.70 64
Pseudomonas putida KT2440 0.36 PP_4977 5,10-methylenetetrahydrofolate reductase 0.51 PP_3446 threonine deaminase low > 96
Dyella japonica UNC79MFTsu3.2 0.36 ABZR86_RS11570 methylenetetrahydrofolate reductase [NAD(P)H] 0.49 ABZR86_RS15925 threonine ammonia-lyase, biosynthetic low > 74
Pseudomonas stutzeri RCH2 0.36 Psest_0313 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.50 Psest_3866 threonine ammonia-lyase, biosynthetic, long form 0.90 10
Pseudomonas syringae pv. syringae B728a 0.36 Psyr_0459 5,10-methylenetetrahydrofolate reductase 0.49 Psyr_4846 L-threonine ammonia-lyase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.36 Psyr_0459 5,10-methylenetetrahydrofolate reductase 0.49 Psyr_4846 L-threonine ammonia-lyase low > 86
Castellaniella sp019104865 MT123 0.35 ABCV34_RS13550 methylenetetrahydrofolate reductase [NAD(P)H] 0.51 ABCV34_RS14460 threonine ammonia-lyase, biosynthetic low > 48
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF1692 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.51 GFF1379 Threonine dehydratase biosynthetic (EC 4.3.1.19)
Acidovorax sp. GW101-3H11 0.34 Ac3H11_3045 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.50 Ac3H11_2042 Threonine dehydratase biosynthetic (EC 4.3.1.19) 0.65 57
Variovorax sp. OAS795 0.33 ABID97_RS25015 methylenetetrahydrofolate reductase [NAD(P)H] 0.49 ABID97_RS07000 threonine ammonia-lyase, biosynthetic 0.59 63
Variovorax sp. SCN45 0.32 GFF2055 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.50 GFF5246 Threonine dehydratase biosynthetic (EC 4.3.1.19) low > 127
Acinetobacter radioresistens SK82 0.32 MPMX26_01002 5,10-methylenetetrahydrofolate reductase 0.47 MPMX26_01278 L-threonine dehydratase biosynthetic IlvA low > 36

Not shown: 30 genomes with orthologs for BWI76_RS00805 only; 0 genomes with orthologs for BWI76_RS00980 only