Conservation of cofitness between BPHYT_RS16975 and BPHYT_RS33835 in Burkholderia phytofirmans PsJN

70 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Burkholderia phytofirmans PsJN 1.0 BPHYT_RS16975 shikimate 5-dehydrogenase 1.0 BPHYT_RS33835 O-succinylhomoserine sulfhydrylase 0.74 12
Paraburkholderia graminis OAS925 0.93 ABIE53_003560 shikimate dehydrogenase 0.93 ABIE53_004817 O-succinylhomoserine sulfhydrylase — —
Paraburkholderia bryophila 376MFSha3.1 0.90 H281DRAFT_06291 shikimate dehydrogenase (EC 1.1.1.25) 0.94 H281DRAFT_06059 O-succinylhomoserine sulfhydrylase — —
Paraburkholderia sabiae LMG 24235 0.81 QEN71_RS27130 shikimate dehydrogenase 0.88 QEN71_RS17685 O-succinylhomoserine sulfhydrylase low > 153
Cupriavidus basilensis FW507-4G11 0.51 RR42_RS17645 shikimate dehydrogenase 0.73 RR42_RS14320 O-succinylhomoserine sulfhydrylase 0.82 14
Pseudomonas sp. S08-1 0.47 OH686_12485 Shikimate 5-dehydrogenase I alpha 0.56 OH686_04415 O-succinylhomoserine sulfhydrylase low > 80
Pseudomonas putida KT2440 0.47 PP_0074 shikimate 5-dehydrogenase 0.53 PP_2001 O-succinylhomoserine sulfhydrylase — —
Shewanella sp. ANA-3 0.47 Shewana3_0043 aroE shikimate 5-dehydrogenase (RefSeq) 0.40 Shewana3_2643 methionine gamma-lyase (RefSeq) low > 73
Pseudomonas syringae pv. syringae B728a ΔmexB 0.46 Psyr_0025 shikimate dehydrogenase 0.57 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.57 51
Pseudomonas syringae pv. syringae B728a 0.46 Psyr_0025 shikimate dehydrogenase 0.57 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.70 5
Pseudomonas sp. RS175 0.46 PFR28_04655 Shikimate dehydrogenase (NADP(+)) 0.55 PFR28_02810 O-succinylhomoserine sulfhydrylase — —
Pseudomonas fluorescens FW300-N2C3 0.45 AO356_11315 shikimate dehydrogenase 0.55 AO356_21470 O-succinylhomoserine sulfhydrylase 0.49 45
Pseudomonas simiae WCS417 0.45 PS417_00125 shikimate dehydrogenase 0.55 PS417_18530 O-succinylhomoserine sulfhydrylase — —
Pseudomonas fluorescens SBW25-INTG 0.45 PFLU_RS00120 shikimate dehydrogenase 0.55 PFLU_RS20510 O-succinylhomoserine sulfhydrylase — —
Pseudomonas fluorescens FW300-N2E2 0.45 Pf6N2E2_4130 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) 0.55 Pf6N2E2_77 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) — —
Pseudomonas fluorescens FW300-N1B4 0.45 Pf1N1B4_1906 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) 0.33 Pf1N1B4_4890 Cystathionine gamma-lyase (EC 4.4.1.1) low > 87
Pseudomonas fluorescens SBW25 0.45 PFLU_RS00120 shikimate dehydrogenase 0.55 PFLU_RS20510 O-succinylhomoserine sulfhydrylase — —
Vibrio cholerae E7946 ATCC 55056 0.45 CSW01_00280 shikimate dehydrogenase 0.27 CSW01_13550 O-succinylhomoserine (thiol)-lyase low > 62
Marinobacter adhaerens HP15 0.45 HP15_3750 shikimate dehydrogenase 0.55 HP15_1820 methionine gamma-lyase — —
Pseudomonas fluorescens GW456-L13 0.45 PfGW456L13_644 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) 0.55 PfGW456L13_3934 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.80 8
Pseudomonas stutzeri RCH2 0.44 Psest_0029 shikimate 5-dehydrogenase 0.54 Psest_2578 O-succinylhomoserine sulfhydrylase — —
Castellaniella sp019104865 MT123 0.44 ABCV34_RS11630 shikimate dehydrogenase 0.34 ABCV34_RS15785 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme low > 48
Shewanella oneidensis MR-1 0.44 SO0040 aroE shikimate 5-dehydrogenase (NCBI ptt file) 0.40 SO1812 mdeA Methionine gamma-lyase (EC 4.4.1.11) (from data) low > 76
Pseudomonas fluorescens FW300-N2E3 0.44 AO353_10670 shikimate dehydrogenase 0.55 AO353_20695 O-succinylhomoserine sulfhydrylase 0.77 8
Shewanella amazonensis SB2B 0.41 Sama_0052 shikimate dehydrogenase (RefSeq) 0.37 Sama_1242 methionine gamma-lyase (RefSeq) low > 62
Pantoea sp. MT58 0.40 IAI47_02315 shikimate dehydrogenase 0.28 IAI47_00880 cystathionine gamma-synthase — —
Shewanella loihica PV-4 0.40 Shew_3727 shikimate 5-dehydrogenase (RefSeq) 0.35 Shew_2491 methionine gamma-lyase (RefSeq) low > 60
Escherichia coli HS(pFamp)R (ATCC 700891) 0.39 OHPLBJKB_00422 Shikimate dehydrogenase (NADP(+)) 0.31 OHPLBJKB_04111 Cystathionine gamma-synthase low > 73
Escherichia coli BL21 0.39 ECD_03132 dehydroshikimate reductase, NAD(P)-binding 0.31 ECD_03825 cystathionine gamma-synthase, PLP-dependent low > 61
Escherichia coli BW25113 0.39 b3281 aroE dehydroshikimate reductase, NAD(P)-binding (NCBI) 0.31 b3939 metB cystathionine gamma-synthase (NCBI) 0.85 56
Escherichia coli ECRC62 0.39 BNILDI_02165 aroE shikimate dehydrogenase 0.31 BNILDI_05715 metB cystathionine gamma-synthase 0.92 34
Escherichia coli ECOR27 0.39 NOLOHH_09355 aroE shikimate dehydrogenase 0.31 NOLOHH_05820 metB cystathionine gamma-synthase 0.84 51
Escherichia coli ECOR38 0.39 HEPCGN_16385 aroE shikimate dehydrogenase 0.31 HEPCGN_12345 metB cystathionine gamma-synthase 0.82 28
Escherichia coli ECRC98 0.38 JDDGAC_21185 aroE shikimate dehydrogenase 0.31 JDDGAC_17300 metB cystathionine gamma-synthase 0.77 61
Escherichia coli ECRC102 0.38 NIAGMN_15325 aroE shikimate dehydrogenase 0.31 NIAGMN_11430 metB cystathionine gamma-synthase — —
Escherichia coli ECRC99 0.38 KEDOAH_10585 aroE shikimate dehydrogenase 0.31 KEDOAH_14485 metB cystathionine gamma-synthase — —
Escherichia coli ECRC101 0.38 MCAODC_08085 aroE shikimate dehydrogenase 0.31 MCAODC_04175 metB cystathionine gamma-synthase 0.86 10
Escherichia coli ECRC100 0.38 OKFHMN_17565 aroE shikimate dehydrogenase 0.31 OKFHMN_13675 metB cystathionine gamma-synthase 0.96 18
Escherichia coli Nissle 1917 0.38 ECOLIN_RS18840 shikimate dehydrogenase 0.31 ECOLIN_RS22725 cystathionine gamma-synthase 0.75 32
Escherichia fergusonii Becca 0.38 EFB2_00542 Shikimate dehydrogenase (NADP(+)) 0.31 EFB2_04679 Cystathionine gamma-synthase low > 86
Enterobacter asburiae PDN3 0.37 EX28DRAFT_0046 shikimate dehydrogenase 0.31 EX28DRAFT_1678 Cystathionine beta-lyases/cystathionine gamma-synthases low > 76
Erwinia tracheiphila SCR3 0.37 LU632_RS22445 aroE shikimate dehydrogenase 0.30 LU632_RS19640 metB cystathionine gamma-synthase 0.61 9
Klebsiella michiganensis M5al 0.36 BWI76_RS25645 shikimate dehydrogenase 0.32 BWI76_RS24210 cystathionine gamma-lyase low > 92
Enterobacter sp. TBS_079 0.36 MPMX20_04189 Shikimate dehydrogenase (NADP(+)) 0.31 MPMX20_01953 Cystathionine beta-lyase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.36 GFF2397 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) 0.31 GFF2323 Cystathionine gamma-synthase (EC 2.5.1.48) low > 78
Variovorax sp. SCN45 0.35 GFF4456 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) 0.56 GFF3088 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) — —
Acinetobacter radioresistens SK82 0.35 MPMX26_02748 Shikimate dehydrogenase (NADP(+)) 0.58 MPMX26_01645 O-succinylhomoserine sulfhydrylase low > 36
Dickeya dianthicola ME23 0.35 DZA65_RS20315 shikimate dehydrogenase 0.31 DZA65_RS21470 cystathionine gamma-synthase — —
Dickeya dadantii 3937 0.35 DDA3937_RS19100 shikimate dehydrogenase 0.31 DDA3937_RS00950 cystathionine gamma-synthase — —
Dickeya dianthicola 67-19 0.35 HGI48_RS19190 shikimate dehydrogenase 0.31 HGI48_RS20425 cystathionine gamma-synthase — —
Variovorax sp. OAS795 0.34 ABID97_RS06300 shikimate dehydrogenase 0.58 ABID97_RS21630 O-succinylhomoserine sulfhydrylase — —
Pectobacterium carotovorum WPP14 0.33 HER17_RS02250 shikimate dehydrogenase 0.34 HER17_RS07405 PLP-dependent aspartate aminotransferase family protein low > 75
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.5020.1 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) 0.33 Xcc-8004.4517.1 Cystathionine gamma-lyase (EC 4.4.1.1) low > 74
Lysobacter sp. OAE881 0.29 ABIE51_RS01815 shikimate dehydrogenase 0.33 ABIE51_RS04295 cystathionine gamma-synthase low > 62
Kangiella aquimarina DSM 16071 0.28 B158DRAFT_0259 shikimate 5-dehydrogenase 0.40 B158DRAFT_1522 methionine gamma-lyase low > 40
Rhodopseudomonas palustris CGA009 0.21 TX73_022410 shikimate dehydrogenase 0.48 TX73_024775 O-succinylhomoserine sulfhydrylase — —
Sinorhizobium meliloti 1021 0.20 SMc02791 shikimate 5-dehydrogenase 0.45 SMc02217 O-succinylhomoserine sulfhydrylase — —
Phaeobacter inhibens DSM 17395 0.19 PGA1_c35150 shikimate dehydrogenase AroE 0.49 PGA1_c23540 O-succinylhomoserine sulfhydrylase MetZ — —
Rhodospirillum rubrum S1H 0.19 Rru_A3613 Quinate/Shikimate 5-dehydrogenase (NCBI) 0.48 Rru_A3214 O-succinylhomoserine sulfhydrylase (NCBI) — —
Rhizobium sp. OAE497 0.19 ABIE40_RS19250 shikimate dehydrogenase 0.45 ABIE40_RS02340 O-succinylhomoserine sulfhydrylase — —
Azospirillum sp. SherDot2 0.19 MPMX19_02560 Shikimate dehydrogenase (NADP(+)) 0.46 MPMX19_01364 O-succinylhomoserine sulfhydrylase — —
Bosea sp. OAE506 0.18 ABIE41_RS04650 shikimate dehydrogenase 0.48 ABIE41_RS03970 O-succinylhomoserine sulfhydrylase — —
Azospirillum brasilense Sp245 0.18 AZOBR_RS01765 shikimate 5-dehydrogenase 0.46 AZOBR_RS02140 O-succinylhomoserine sulfhydrylase — —
Caulobacter crescentus NA1000 0.17 CCNA_00003 shikimate dehydrogenase (EC 1.1.1.25) (from data) 0.44 CCNA_02321 O-succinylhomoserine sulfhydrylase 0.87 41
Caulobacter crescentus NA1000 Δfur 0.17 CCNA_00003 shikimate 5-dehydrogenase 0.44 CCNA_02321 O-succinylhomoserine sulfhydrylase low > 67
Mucilaginibacter yixingensis YX-36 DSM 26809 0.15 ABZR88_RS20055 shikimate dehydrogenase 0.31 ABZR88_RS06685 cystathionine gamma-synthase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.14 Echvi_1145 Shikimate 5-dehydrogenase 0.48 Echvi_2283 Cystathionine beta-lyases/cystathionine gamma-synthases — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.14 CA264_19075 shikimate dehydrogenase 0.45 CA264_02530 O-succinylhomoserine sulfhydrylase — —
Magnetospirillum magneticum AMB-1 0.14 AMB_RS23010 shikimate dehydrogenase 0.50 AMB_RS21365 O-succinylhomoserine sulfhydrylase — —
Pedobacter sp. GW460-11-11-14-LB5 0.13 CA265_RS19745 shikimate dehydrogenase (EC 1.1.1.25) (from data) 0.46 CA265_RS13080 O-succinylhomoserine sulfhydrylase — —
Mycobacterium tuberculosis H37Rv 0.11 Rv2552c Probable shikimate 5-dehydrogenase AroE (5-dehydroshikimate reductase) 0.47 Rv0391 Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase) — —

Not shown: 20 genomes with orthologs for BPHYT_RS16975 only; 11 genomes with orthologs for BPHYT_RS33835 only