| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Agrobacterium fabrum C58 | 1.0 | Atu2747 | | hypothetical protein | 1.0 | Atu3731 | | 5-formyltetrahydrofolate cyclo-ligase | 0.86 | 15 |
| Sinorhizobium meliloti 1021 | 0.77 | SMc02812 | | hypothetical protein | 0.56 | SMc03974 | | hypothetical protein | 0.47 | 51 |
| Rhizobium sp. OAE497 | 0.76 | ABIE40_RS19180 | | YggS family pyridoxal phosphate-dependent enzyme | 0.62 | ABIE40_RS15645 | | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Rhodopseudomonas palustris CGA009 | 0.59 | TX73_001485 | | YggS family pyridoxal phosphate-dependent enzyme | 0.33 | TX73_023120 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 86 |
| Bosea sp. OAE506 | 0.58 | ABIE41_RS04720 | | YggS family pyridoxal phosphate-dependent enzyme | 0.29 | ABIE41_RS09445 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 77 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.53 | A4249_RS13760 | | YggS family pyridoxal phosphate-dependent enzyme | 0.18 | A4249_RS00800 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 48 |
| Ralstonia solanacearum GMI1000 | 0.53 | RS_RS20395 | | YggS family pyridoxal phosphate-dependent enzyme | 0.23 | RS_RS00450 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 80 |
| Phaeobacter inhibens DSM 17395 | 0.53 | PGA1_c33360 | | putative alanine racemase | 0.21 | PGA1_c21820 | | 5-formyltetrahydrofolate cycloligase-like protein | low | > 62 |
| Ralstonia solanacearum PSI07 | 0.51 | RPSI07_RS02580 | | YggS family pyridoxal phosphate-dependent enzyme | 0.25 | RPSI07_RS23505 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 81 |
| Ralstonia solanacearum IBSBF1503 | 0.51 | RALBFv3_RS20285 | | YggS family pyridoxal phosphate-dependent enzyme | 0.23 | RALBFv3_RS09865 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 76 |
| Ralstonia solanacearum UW163 | 0.51 | UW163_RS18890 | | YggS family pyridoxal phosphate-dependent enzyme | 0.23 | UW163_RS03715 | | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Shewanella loihica PV-4 | 0.37 | Shew_1137 | | alanine racemase domain-containing protein (RefSeq) | 0.20 | Shew_3069 | | 5-formyltetrahydrofolate cyclo-ligase (RefSeq) | low | > 60 |
| Herbaspirillum seropedicae SmR1 | 0.35 | HSERO_RS18995 | | hypothetical protein | 0.20 | HSERO_RS21420 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 78 |
| Paraburkholderia sabiae LMG 24235 | 0.35 | QEN71_RS26595 | | YggS family pyridoxal phosphate-dependent enzyme | 0.14 | QEN71_RS28640 | | 5-formyltetrahydrofolate cyclo-ligase | 0.43 | 56 |
| Shewanella sp. ANA-3 | 0.34 | Shewana3_1194 | | hypothetical protein (RefSeq) | 0.23 | Shewana3_3506 | | 5-formyltetrahydrofolate cyclo-ligase (RefSeq) | low | > 73 |
| Vibrio cholerae E7946 ATCC 55056 | 0.34 | CSW01_02455 | | YggS family pyridoxal phosphate enzyme | 0.22 | CSW01_12545 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 62 |
| Ralstonia sp. UNC404CL21Col | 0.33 | ABZR87_RS01225 | | YggS family pyridoxal phosphate-dependent enzyme | 0.23 | ABZR87_RS04880 | | 5-formyltetrahydrofolate cyclo-ligase | 0.46 | 48 |
| Enterobacter asburiae PDN3 | 0.32 | EX28DRAFT_2989 | | pyridoxal phosphate enzyme, YggS family | 0.22 | EX28DRAFT_2964 | | 5,10-methenyltetrahydrofolate synthetase | low | > 76 |
| Variovorax sp. OAS795 | 0.32 | ABID97_RS00250 | | YggS family pyridoxal phosphate-dependent enzyme | 0.15 | ABID97_RS06600 | | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.32 | LRK54_RS02905 | | YggS family pyridoxal phosphate-dependent enzyme | 0.18 | LRK54_RS11670 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 59 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.32 | GFF2722 | | Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC | 0.16 | GFF1613 | | 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) | low | > 90 |
| Shewanella oneidensis MR-1 | 0.32 | SO3352 | | conserved hypothetical protein TIGR00044 (NCBI ptt file) | 0.22 | SO0774 | | 5-formyltetrahydrofolate cyclo-ligase family protein (NCBI ptt file) | 0.33 | 59 |
| Rhodanobacter denitrificans MT42 | 0.32 | LRK55_RS02655 | | YggS family pyridoxal phosphate-dependent enzyme | 0.18 | LRK55_RS11395 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 63 |
| Kangiella aquimarina DSM 16071 | 0.32 | B158DRAFT_0196 | | pyridoxal phosphate enzyme, YggS family | 0.20 | B158DRAFT_0528 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 40 |
| Pseudomonas syringae pv. syringae B728a | 0.31 | Psyr_0477 | | Protein of unknown function UPF0001 | 0.16 | Psyr_0317 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 86 |
| Pseudomonas fluorescens FW300-N2E3 | 0.31 | AO353_10505 | | hypothetical protein | 0.15 | AO353_08780 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 101 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.31 | Psyr_0477 | | Protein of unknown function UPF0001 | 0.16 | Psyr_0317 | | 5-formyltetrahydrofolate cyclo-ligase | 0.49 | 55 |
| Klebsiella michiganensis M5al | 0.31 | BWI76_RS24100 | | YggS family pyridoxal phosphate enzyme | 0.21 | BWI76_RS23915 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 92 |
| Lysobacter sp. OAE881 | 0.31 | ABIE51_RS16060 | | YggS family pyridoxal phosphate-dependent enzyme | 0.19 | ABIE51_RS17355 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 62 |
| Enterobacter sp. TBS_079 | 0.30 | MPMX20_03809 | | Pyridoxal phosphate homeostasis protein | 0.22 | MPMX20_03770 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 85 |
| Pectobacterium carotovorum WPP14 | 0.30 | HER17_RS03810 | | YggS family pyridoxal phosphate-dependent enzyme | 0.23 | HER17_RS19095 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 75 |
| Pseudomonas sp. S08-1 | 0.30 | OH686_10975 | | Pyridoxal phosphate-containing protein YggS | 0.16 | OH686_11225 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 80 |
| Escherichia fergusonii Becca | 0.30 | EFB2_00951 | | Pyridoxal phosphate homeostasis protein | 0.22 | EFB2_00991 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 86 |
| Escherichia coli BL21 | 0.30 | ECD_02781 | | UPF0001 family protein, PLP-binding | 0.22 | ECD_02743 | | 5-formyltetrahydrofolate cyclo-ligase family protein | low | > 60 |
| Escherichia coli ECRC62 | 0.30 | BNILDI_09705 | yggS | pyridoxal phosphate homeostasis protein | 0.22 | BNILDI_09930 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Escherichia coli ECRC101 | 0.30 | OKFHMN_19255 | yggS | pyridoxal phosphate homeostasis protein | 0.22 | OKFHMN_19485 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Escherichia coli ECRC102 | 0.30 | NIAGMN_17020 | yggS | pyridoxal phosphate homeostasis protein | 0.22 | NIAGMN_17250 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Escherichia coli ECOR27 | 0.30 | NOLOHH_11125 | yggS | pyridoxal phosphate homeostasis protein | 0.22 | NOLOHH_11395 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | low | > 57 |
| Escherichia coli BW25113 | 0.30 | b2951 | yggS | predicted enzyme (NCBI) | 0.22 | b2912 | ygfA | putative ligase (VIMSS) | 0.24 | 24 |
| Escherichia coli ECRC101 | 0.30 | MCAODC_09775 | yggS | pyridoxal phosphate homeostasis protein | 0.22 | MCAODC_10005 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.30 | OHPLBJKB_00765 | | Pyridoxal phosphate homeostasis protein | 0.22 | OHPLBJKB_00804 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 73 |
| Escherichia coli ECOR38 | 0.30 | HEPCGN_18560 | yggS | pyridoxal phosphate homeostasis protein | 0.22 | HEPCGN_18775 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | low | > 85 |
| Escherichia coli ECRC98 | 0.30 | JDDGAC_22885 | yggS | pyridoxal phosphate homeostasis protein | 0.22 | JDDGAC_23125 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Escherichia coli Nissle 1917 | 0.30 | ECOLIN_RS16415 | | pyridoxal phosphate homeostasis protein | 0.22 | ECOLIN_RS16205 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 52 |
| Escherichia coli ECRC99 | 0.30 | KEDOAH_08885 | yggS | pyridoxal phosphate homeostasis protein | 0.22 | KEDOAH_08655 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.30 | GFF3054 | | Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC | 0.20 | GFF3012 | | 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) | low | > 78 |
| Dechlorosoma suillum PS | 0.30 | Dsui_0603 | | pyridoxal phosphate enzyme, YggS family | 0.22 | Dsui_0682 | | 5,10-methenyltetrahydrofolate synthetase | — | — |
| Rhodanobacter sp. FW510-T8 | 0.29 | OKGIIK_09885 | | Pyridoxal phosphate homeostasis protein | 0.19 | OKGIIK_12225 | | 5-formyltetrahydrofolate cyclo-ligase | 0.50 | 16 |
| Dyella japonica UNC79MFTsu3.2 | 0.29 | ABZR86_RS09305 | | YggS family pyridoxal phosphate-dependent enzyme | 0.17 | ABZR86_RS11995 | | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Pseudomonas stutzeri RCH2 | 0.29 | Psest_0284 | | pyridoxal phosphate enzyme, YggS family | 0.19 | Psest_0170 | | 5,10-methenyltetrahydrofolate synthetase | low | > 67 |
| Rahnella sp. WP5 | 0.29 | EX31_RS02685 | | YggS family pyridoxal phosphate-dependent enzyme | 0.23 | EX31_RS21480 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 89 |
| Pseudomonas fluorescens FW300-N2C3 | 0.29 | AO356_13425 | | hypothetical protein | 0.15 | AO356_12990 | | 5-formyltetrahydrofolate cyclo-ligase | 0.29 | 9 |
| Pantoea sp. MT58 | 0.29 | IAI47_03595 | | YggS family pyridoxal phosphate-dependent enzyme | 0.20 | IAI47_03730 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 76 |
| Pseudomonas simiae WCS417 | 0.28 | PS417_26725 | | hypothetical protein | 0.16 | PS417_27305 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 88 |
| Pseudomonas putida KT2440 | 0.28 | PP_5094 | | putative enzyme with PLP binding domain | 0.16 | PP_5203 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 96 |
| Cupriavidus basilensis FW507-4G11 | 0.28 | RR42_RS17355 | | hypothetical protein | 0.16 | RR42_RS01400 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 128 |
| Erwinia tracheiphila SCR3 | 0.28 | LU632_RS05460 | | YggS family pyridoxal phosphate-dependent enzyme | 0.21 | LU632_RS05860 | | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.27 | PfGW456L13_1011 | | Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC | 0.17 | PfGW456L13_892 | | 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) | low | > 87 |
| Pseudomonas fluorescens SBW25 | 0.27 | PFLU_RS28370 | | YggS family pyridoxal phosphate-dependent enzyme | 0.16 | PFLU_RS28965 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.27 | PFLU_RS28370 | | YggS family pyridoxal phosphate-dependent enzyme | 0.16 | PFLU_RS28965 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 109 |
| Acinetobacter radioresistens SK82 | 0.27 | MPMX26_02404 | | Pyridoxal phosphate homeostasis protein | 0.15 | MPMX26_02298 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 36 |
| Pseudomonas fluorescens FW300-N2E2 | 0.27 | Pf6N2E2_4601 | | Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC | 0.14 | Pf6N2E2_4476 | | 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) | 0.29 | 17 |
| Marinobacter adhaerens HP15 | 0.26 | HP15_288 | | alanine racemase domain protein | 0.16 | HP15_3211 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 73 |
| Pseudomonas sp. RS175 | 0.26 | PFR28_04242 | | Pyridoxal phosphate homeostasis protein | 0.15 | PFR28_04325 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 88 |
| Synechococcus elongatus PCC 7942 | 0.26 | Synpcc7942_2060 | ylmE | hypothetical protein | 0.17 | Synpcc7942_1300 | | hypothetical protein | 0.42 | 36 |
| Serratia liquefaciens MT49 | 0.25 | IAI46_21410 | | YggS family pyridoxal phosphate-dependent enzyme | 0.25 | IAI46_20895 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 86 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.25 | Xcc-8004.1711.1 | | Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC | 0.17 | Xcc-8004.1138.1 | | 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) | 0.57 | 30 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.24 | Echvi_2233 | | pyridoxal phosphate enzyme, YggS family | 0.18 | Echvi_1511 | | 5,10-methenyltetrahydrofolate synthetase | low | > 79 |
| Bacteroides ovatus ATCC 8483 | 0.24 | BACOVA_00593 | | pyridoxal phosphate enzyme, YggS family | 0.14 | BACOVA_05091 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 94 |
| Bacteroides stercoris CC31F | 0.23 | HMPREF1181_RS10865 | | YggS family pyridoxal phosphate-dependent enzyme | 0.15 | HMPREF1181_RS06170 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 56 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.23 | CA264_06410 | | YggS family pyridoxal phosphate enzyme | 0.18 | CA264_15880 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 74 |
| Mycobacterium tuberculosis H37Rv | 0.21 | Rv2148c | | Conserved protein | 0.14 | Rv0992c | | Conserved hypothetical protein | low | > 58 |
Not shown: 29 genomes with orthologs for Atu2747 only; 1 genomes with orthologs for Atu3731 only