Conservation of cofitness between BT3757 and BT3395 in Bacteroides thetaiotaomicron VPI-5482

68 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT3757 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 1.0 BT3395 N-succinylglutamate kinase (EC 2.7.2.-) (from data) 0.88 19
Bacteroides ovatus ATCC 8483 0.92 BACOVA_03587 pyrroline-5-carboxylate reductase 0.96 BACOVA_01910 acetylglutamate kinase 0.89 24
Bacteroides stercoris CC31F 0.78 HMPREF1181_RS03440 pyrroline-5-carboxylate reductase 0.87 HMPREF1181_RS02540 acetylglutamate kinase 0.95 13
Phocaeicola vulgatus CL09T03C04 0.69 HMPREF1058_RS08830 pyrroline-5-carboxylate reductase 0.86 HMPREF1058_RS12115 acetylglutamate kinase low > 67
Phocaeicola dorei CL03T12C01 0.69 ABI39_RS02960 pyrroline-5-carboxylate reductase 0.85 ABI39_RS04685 acetylglutamate kinase 0.73 49
Parabacteroides merdae CL09T00C40 0.51 HMPREF1078_RS10620 pyrroline-5-carboxylate reductase 0.77 HMPREF1078_RS15335 acetylglutamate kinase 0.95 27
Mucilaginibacter yixingensis YX-36 DSM 26809 0.39 ABZR88_RS09865 pyrroline-5-carboxylate reductase 0.56 ABZR88_RS09860 acetylglutamate kinase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.34 Echvi_2479 pyrroline-5-carboxylate reductase 0.52 Echvi_3850 acetylglutamate kinase 0.77 19
Pedobacter sp. GW460-11-11-14-LB5 0.34 CA265_RS18505 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.55 CA265_RS18510 acetylglutamate kinase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.33 CA264_07730 pyrroline-5-carboxylate reductase 0.54 CA264_06235 acetylglutamate kinase low > 74
Escherichia coli HS(pFamp)R (ATCC 700891) 0.24 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase 0.15 OHPLBJKB_04091 Acetylglutamate kinase low > 73
Erwinia tracheiphila SCR3 0.24 LU632_RS18995 proC pyrroline-5-carboxylate reductase 0.16 LU632_RS19610 argB acetylglutamate kinase low > 74
Escherichia coli BL21 0.24 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding 0.15 ECD_03844 acetylglutamate kinase low > 60
Escherichia coli BW25113 0.24 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 0.15 b3959 argB acetylglutamate kinase (RefSeq) 0.82 41
Escherichia coli ECRC62 0.24 BNILDI_22950 proC pyrroline-5-carboxylate reductase 0.15 BNILDI_05800 acetylglutamate kinase — —
Escherichia coli Nissle 1917 0.24 ECOLIN_RS02345 pyrroline-5-carboxylate reductase 0.15 ECOLIN_RS22850 acetylglutamate kinase low > 52
Escherichia fergusonii Becca 0.24 EFB2_03670 Pyrroline-5-carboxylate reductase 0.15 EFB2_04655 Acetylglutamate kinase low > 86
Escherichia coli ECOR27 0.24 NOLOHH_01535 proC pyrroline-5-carboxylate reductase 0.15 NOLOHH_05725 acetylglutamate kinase low > 57
Escherichia coli ECOR38 0.24 HEPCGN_07250 proC pyrroline-5-carboxylate reductase 0.15 HEPCGN_12225 acetylglutamate kinase low > 85
Klebsiella michiganensis M5al 0.24 BWI76_RS06170 pyrroline-5-carboxylate reductase 0.15 BWI76_RS00850 acetylglutamate kinase — —
Escherichia coli ECRC99 0.24 KEDOAH_19355 proC pyrroline-5-carboxylate reductase 0.15 KEDOAH_14580 acetylglutamate kinase — —
Escherichia coli ECRC98 0.24 JDDGAC_12265 proC pyrroline-5-carboxylate reductase 0.15 JDDGAC_17205 acetylglutamate kinase — —
Escherichia coli ECRC102 0.24 NIAGMN_06665 proC pyrroline-5-carboxylate reductase 0.15 NIAGMN_11330 acetylglutamate kinase — —
Escherichia coli ECRC101 0.24 MCAODC_27835 proC pyrroline-5-carboxylate reductase 0.15 MCAODC_04080 acetylglutamate kinase — —
Escherichia coli ECRC101 0.24 OKFHMN_08610 proC pyrroline-5-carboxylate reductase 0.15 OKFHMN_13580 acetylglutamate kinase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.24 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.13 GFF2345 Acetylglutamate kinase (EC 2.7.2.8) low > 78
Pseudomonas stutzeri RCH2 0.23 Psest_0283 pyrroline-5-carboxylate reductase 0.26 Psest_3807 acetylglutamate kinase — —
Enterobacter asburiae PDN3 0.23 EX28DRAFT_2585 pyrroline-5-carboxylate reductase 0.14 EX28DRAFT_4421 N-acetylglutamate kinase (EC 2.7.2.8) 0.67 20
Enterobacter sp. TBS_079 0.23 MPMX20_00976 Pyrroline-5-carboxylate reductase 0.14 MPMX20_04521 Acetylglutamate kinase 0.89 22
Pseudomonas fluorescens SBW25 0.23 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.25 PFLU_RS29470 acetylglutamate kinase — —
Pseudomonas fluorescens SBW25-INTG 0.23 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.25 PFLU_RS29470 acetylglutamate kinase — —
Pseudomonas fluorescens GW456-L13 0.23 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.25 PfGW456L13_793 Acetylglutamate kinase (EC 2.7.2.8) 0.60 86
Alteromonas macleodii MIT1002 0.23 MIT1002_03062 Pyrroline-5-carboxylate reductase 0.18 MIT1002_00470 Acetylglutamate kinase 0.96 24
Pseudomonas simiae WCS417 0.22 PS417_26730 pyrroline-5-carboxylate reductase 0.25 PS417_27790 acetylglutamate kinase — —
Pseudomonas fluorescens FW300-N2C3 0.22 AO356_13420 pyrroline-5-carboxylate reductase 0.25 AO356_12525 acetylglutamate kinase — —
Pseudomonas sp. RS175 0.22 PFR28_04243 Pyrroline-5-carboxylate reductase 0.25 PFR28_04416 Acetylglutamate kinase — —
Pseudomonas fluorescens FW300-N2E3 0.21 AO353_08165 pyrroline-5-carboxylate reductase 0.25 AO353_09240 acetylglutamate kinase 0.68 15
Pseudomonas fluorescens FW300-N2E2 0.21 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.25 Pf6N2E2_4373 Acetylglutamate kinase (EC 2.7.2.8) — —
Pantoea sp. MT58 0.21 IAI47_14945 pyrroline-5-carboxylate reductase 0.17 IAI47_00910 acetylglutamate kinase 0.74 71
Marinobacter adhaerens HP15 0.21 HP15_287 pyrroline-5-carboxylate reductase 0.25 HP15_3317 acetylglutamate kinase 0.68 14
Shewanella loihica PV-4 0.21 Shew_1136 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.17 Shew_0203 acetylglutamate kinase (RefSeq) 0.95 7
Shewanella oneidensis MR-1 0.20 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) 0.17 SO0276 argB acetylglutamate kinase (NCBI ptt file) 0.93 42
Pseudomonas fluorescens FW300-N1B4 0.20 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.25 Pf1N1B4_2121 Acetylglutamate kinase (EC 2.7.2.8) — —
Vibrio cholerae E7946 ATCC 55056 0.20 CSW01_02450 pyrroline-5-carboxylate reductase 0.16 CSW01_13375 acetylglutamate kinase low > 62
Shewanella amazonensis SB2B 0.20 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) 0.16 Sama_0257 acetylglutamate kinase (RefSeq) 0.93 32
Paraburkholderia graminis OAS925 0.20 ABIE53_000840 pyrroline-5-carboxylate reductase 0.22 ABIE53_000417 acetylglutamate kinase — —
Burkholderia phytofirmans PsJN 0.19 BPHYT_RS03490 pyrroline-5-carboxylate reductase 0.22 BPHYT_RS01610 acetylglutamate kinase — —
Paraburkholderia bryophila 376MFSha3.1 0.19 H281DRAFT_04679 pyrroline-5-carboxylate reductase 0.22 H281DRAFT_02211 N-acetylglutamate kinase — —
Shewanella sp. ANA-3 0.19 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) 0.17 Shewana3_3904 acetylglutamate kinase (RefSeq) 0.86 67
Castellaniella sp019104865 MT123 0.19 ABCV34_RS03610 pyrroline-5-carboxylate reductase 0.21 ABCV34_RS14295 acetylglutamate kinase — —
Herbaspirillum seropedicae SmR1 0.19 HSERO_RS18990 pyrroline-5-carboxylate reductase 0.22 HSERO_RS21495 acetylglutamate kinase — —
Variovorax sp. OAS795 0.18 ABID97_RS01555 pyrroline-5-carboxylate reductase 0.22 ABID97_RS05760 acetylglutamate kinase — —
Serratia liquefaciens MT49 0.18 IAI46_21415 pyrroline-5-carboxylate reductase 0.16 IAI46_24510 acetylglutamate kinase 0.53 71
Dickeya dianthicola ME23 0.18 DZA65_RS18440 pyrroline-5-carboxylate reductase 0.16 DZA65_RS00940 acetylglutamate kinase — —
Dickeya dadantii 3937 0.18 DDA3937_RS17305 pyrroline-5-carboxylate reductase 0.17 DDA3937_RS20345 acetylglutamate kinase 0.66 41
Paraburkholderia sabiae LMG 24235 0.18 QEN71_RS26600 pyrroline-5-carboxylate reductase 0.22 QEN71_RS00305 acetylglutamate kinase — —
Dickeya dianthicola 67-19 0.18 HGI48_RS17350 pyrroline-5-carboxylate reductase 0.16 HGI48_RS00880 acetylglutamate kinase — —
Pectobacterium carotovorum WPP14 0.17 HER17_RS03805 pyrroline-5-carboxylate reductase 0.17 HER17_RS20625 acetylglutamate kinase — —
Variovorax sp. SCN45 0.17 GFF5553 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.22 GFF4624 N-acetylglutamate kinase (EC 2.7.2.8) — —
Sphingomonas koreensis DSMZ 15582 0.16 Ga0059261_3321 pyrroline-5-carboxylate reductase 0.23 Ga0059261_2530 N-acetylglutamate kinase (EC 2.7.2.8) low > 68
Rahnella sp. WP5 0.15 EX31_RS02690 pyrroline-5-carboxylate reductase 0.15 EX31_RS14185 acetylglutamate kinase 0.97 14
Rhizobium sp. OAE497 0.14 ABIE40_RS13005 pyrroline-5-carboxylate reductase 0.27 ABIE40_RS01970 acetylglutamate kinase 0.65 69
Sinorhizobium meliloti 1021 0.14 SMc02677 pyrroline-5-carboxylate reductase 0.27 SMc01726 acetylglutamate kinase 0.65 38
Caulobacter crescentus NA1000 Δfur 0.13 CCNA_00528 pyrroline-5-carboxylate reductase 0.22 CCNA_00285 acetylglutamate kinase — —
Caulobacter crescentus NA1000 0.13 CCNA_00528 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.22 CCNA_00285 acetylglutamate kinase — —
Agrobacterium fabrum C58 0.12 Atu2209 pyrroline-5-carboxylate reductase 0.27 Atu0380 acetylglutamate kinase — —
Rhodopseudomonas palustris CGA009 0.12 TX73_022630 pyrroline-5-carboxylate reductase 0.27 TX73_003255 acetylglutamate kinase — —
Dinoroseobacter shibae DFL-12 0.11 Dshi_2645 pyrroline-5-carboxylate reductase (RefSeq) 0.23 Dshi_0324 acetylglutamate kinase (RefSeq) — —
Phaeobacter inhibens DSM 17395 0.11 PGA1_c24700 pyrroline-5-carboxylate reductase ProC 0.26 PGA1_c02050 acetylglutamate kinase ArgB 0.78 33

Not shown: 21 genomes with orthologs for BT3757 only; 9 genomes with orthologs for BT3395 only