Conservation of cofitness between BT3395 and BT1861 in Bacteroides thetaiotaomicron VPI-5482

66 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT3395 N-succinylglutamate kinase (EC 2.7.2.-) (from data) 1.0 BT1861 2-isopropylmalate synthase (EC 2.3.3.13) (from data) 0.90 16
Bacteroides ovatus ATCC 8483 0.96 BACOVA_01910 acetylglutamate kinase 0.99 BACOVA_04604 2-isopropylmalate synthase 0.94 19
Bacteroides stercoris CC31F 0.87 HMPREF1181_RS02540 acetylglutamate kinase 0.92 HMPREF1181_RS14150 2-isopropylmalate synthase 0.90 30
Phocaeicola vulgatus CL09T03C04 0.86 HMPREF1058_RS12115 acetylglutamate kinase 0.90 HMPREF1058_RS14545 2-isopropylmalate synthase 0.48 65
Phocaeicola dorei CL03T12C01 0.85 ABI39_RS04685 acetylglutamate kinase 0.90 ABI39_RS10195 2-isopropylmalate synthase 0.76 29
Parabacteroides merdae CL09T00C40 0.77 HMPREF1078_RS15335 acetylglutamate kinase 0.86 HMPREF1078_RS16665 2-isopropylmalate synthase 0.95 38
Bosea sp. OAE506 0.29 ABIE41_RS03980 acetylglutamate kinase 0.43 ABIE41_RS13000 2-isopropylmalate synthase — —
Sinorhizobium meliloti 1021 0.27 SMc01726 acetylglutamate kinase 0.17 SMc02546 alpha-isopropylmalate/homocitrate synthase family transferase low > 103
Rhodopseudomonas palustris CGA009 0.27 TX73_003255 acetylglutamate kinase 0.42 TX73_010545 2-isopropylmalate synthase — —
Rhizobium sp. OAE497 0.27 ABIE40_RS01970 acetylglutamate kinase 0.17 ABIE40_RS06220 citramalate synthase low > 107
Agrobacterium fabrum C58 0.27 Atu0380 acetylglutamate kinase 0.12 Atu2264 2-isopropylmalate synthase — —
Pseudomonas stutzeri RCH2 0.26 Psest_3807 acetylglutamate kinase 0.46 Psest_1056 2-isopropylmalate synthase, bacterial type — —
Phaeobacter inhibens DSM 17395 0.26 PGA1_c02050 acetylglutamate kinase ArgB 0.45 PGA1_c26470 2-isopropylmalate synthase LeuA 0.74 13
Methanococcus maripaludis JJ 0.26 MMJJ_RS05120 acetylglutamate kinase 0.35 MMJJ_RS08870 2-isopropylmalate synthase — —
Pseudomonas fluorescens GW456-L13 0.25 PfGW456L13_793 Acetylglutamate kinase (EC 2.7.2.8) 0.12 PfGW456L13_4854 2-isopropylmalate synthase (EC 2.3.3.13) 0.58 24
Marinobacter adhaerens HP15 0.25 HP15_3317 acetylglutamate kinase 0.47 HP15_538 2-isopropylmalate synthase low > 73
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_2121 Acetylglutamate kinase (EC 2.7.2.8) 0.12 Pf1N1B4_847 2-isopropylmalate synthase (EC 2.3.3.13) — —
Pseudomonas sp. RS175 0.25 PFR28_04416 Acetylglutamate kinase 0.13 PFR28_00305 2-isopropylmalate synthase — —
Methanococcus maripaludis S2 0.25 MMP_RS00365 acetylglutamate kinase 0.35 MMP_RS05500 2-isopropylmalate synthase — —
Pseudomonas fluorescens FW300-N2C3 0.25 AO356_12525 acetylglutamate kinase 0.13 AO356_06550 2-isopropylmalate synthase 0.89 22
Pseudomonas fluorescens SBW25-INTG 0.25 PFLU_RS29470 acetylglutamate kinase 0.12 PFLU_RS24765 2-isopropylmalate synthase — —
Pseudomonas fluorescens FW300-N2E2 0.25 Pf6N2E2_4373 Acetylglutamate kinase (EC 2.7.2.8) 0.13 Pf6N2E2_3170 2-isopropylmalate synthase (EC 2.3.3.13) — —
Pseudomonas simiae WCS417 0.25 PS417_27790 acetylglutamate kinase 0.12 PS417_23110 2-isopropylmalate synthase — —
Pseudomonas fluorescens SBW25 0.25 PFLU_RS29470 acetylglutamate kinase 0.12 PFLU_RS24765 2-isopropylmalate synthase — —
Dechlorosoma suillum PS 0.24 Dsui_1309 acetylglutamate kinase 0.46 Dsui_3519 2-isopropylmalate synthase, bacterial type — —
Sphingomonas koreensis DSMZ 15582 0.23 Ga0059261_2530 N-acetylglutamate kinase (EC 2.7.2.8) 0.11 Ga0059261_4031 2-isopropylmalate synthase, yeast type 0.99 2
Dinoroseobacter shibae DFL-12 0.23 Dshi_0324 acetylglutamate kinase (RefSeq) 0.42 Dshi_0596 2-isopropylmalate synthase (RefSeq) — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.23 GFF409 Acetylglutamate kinase (EC 2.7.2.8) 0.43 GFF4281 2-isopropylmalate synthase (EC 2.3.3.13) — —
Variovorax sp. SCN45 0.22 GFF4624 N-acetylglutamate kinase (EC 2.7.2.8) 0.43 GFF1165 2-isopropylmalate synthase (EC 2.3.3.13) — —
Caulobacter crescentus NA1000 0.22 CCNA_00285 acetylglutamate kinase 0.45 CCNA_01610 2-isopropylmalate synthase — —
Variovorax sp. OAS795 0.22 ABID97_RS05760 acetylglutamate kinase 0.43 ABID97_RS14910 2-isopropylmalate synthase — —
Caulobacter crescentus NA1000 Δfur 0.22 CCNA_00285 acetylglutamate kinase 0.45 CCNA_01610 2-isopropylmalate synthase — —
Burkholderia phytofirmans PsJN 0.22 BPHYT_RS01610 acetylglutamate kinase 0.43 BPHYT_RS06570 2-isopropylmalate synthase — —
Paraburkholderia sabiae LMG 24235 0.22 QEN71_RS00305 acetylglutamate kinase 0.43 QEN71_RS24195 2-isopropylmalate synthase — —
Paraburkholderia graminis OAS925 0.22 ABIE53_000417 acetylglutamate kinase 0.43 ABIE53_001580 2-isopropylmalate synthase — —
Paraburkholderia bryophila 376MFSha3.1 0.22 H281DRAFT_02211 N-acetylglutamate kinase 0.43 H281DRAFT_04556 2-isopropylmalate synthase — —
Castellaniella sp019104865 MT123 0.21 ABCV34_RS14295 acetylglutamate kinase 0.12 ABCV34_RS12420 2-isopropylmalate synthase — —
Alteromonas macleodii MIT1002 0.18 MIT1002_00470 Acetylglutamate kinase 0.47 MIT1002_00949 2-isopropylmalate synthase 0.97 30
Shewanella sp. ANA-3 0.17 Shewana3_3904 acetylglutamate kinase (RefSeq) 0.47 Shewana3_3761 2-isopropylmalate synthase (RefSeq) 0.87 21
Pectobacterium carotovorum WPP14 0.17 HER17_RS20625 acetylglutamate kinase 0.47 HER17_RS03085 2-isopropylmalate synthase 0.74 34
Shewanella oneidensis MR-1 0.17 SO0276 argB acetylglutamate kinase (NCBI ptt file) 0.47 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.94 19
Shewanella loihica PV-4 0.17 Shew_0203 acetylglutamate kinase (RefSeq) 0.47 Shew_3472 2-isopropylmalate synthase (RefSeq) 0.99 6
Pantoea sp. MT58 0.17 IAI47_00910 acetylglutamate kinase 0.45 IAI47_16000 2-isopropylmalate synthase 0.74 52
Dickeya dadantii 3937 0.17 DDA3937_RS20345 acetylglutamate kinase 0.47 DDA3937_RS18115 2-isopropylmalate synthase 0.68 56
Dickeya dianthicola ME23 0.16 DZA65_RS00940 acetylglutamate kinase 0.47 DZA65_RS19200 2-isopropylmalate synthase 0.72 42
Shewanella amazonensis SB2B 0.16 Sama_0257 acetylglutamate kinase (RefSeq) 0.46 Sama_0335 2-isopropylmalate synthase (RefSeq) 0.91 42
Dickeya dianthicola 67-19 0.16 HGI48_RS00880 acetylglutamate kinase 0.47 HGI48_RS18055 2-isopropylmalate synthase 0.78 7
Erwinia tracheiphila SCR3 0.16 LU632_RS19610 argB acetylglutamate kinase 0.45 LU632_RS02880 leuA 2-isopropylmalate synthase 0.72 41
Vibrio cholerae E7946 ATCC 55056 0.16 CSW01_13375 acetylglutamate kinase 0.48 CSW01_12595 2-isopropylmalate synthase low > 62
Serratia liquefaciens MT49 0.16 IAI46_24510 acetylglutamate kinase 0.47 IAI46_03355 2-isopropylmalate synthase 0.78 30
Rahnella sp. WP5 0.15 EX31_RS14185 acetylglutamate kinase 0.45 EX31_RS03680 2-isopropylmalate synthase 0.94 38
Escherichia fergusonii Becca 0.15 EFB2_04655 Acetylglutamate kinase 0.46 EFB2_03971 2-isopropylmalate synthase low > 86
Escherichia coli Nissle 1917 0.15 ECOLIN_RS22850 acetylglutamate kinase 0.46 ECOLIN_RS00400 2-isopropylmalate synthase low > 52
Escherichia coli HS(pFamp)R (ATCC 700891) 0.15 OHPLBJKB_04091 Acetylglutamate kinase 0.46 OHPLBJKB_03583 2-isopropylmalate synthase low > 73
Escherichia coli BW25113 0.15 b3959 argB acetylglutamate kinase (RefSeq) 0.46 b0074 leuA 2-isopropylmalate synthase (NCBI) 0.90 11
Escherichia coli ECOR27 0.15 NOLOHH_05725 acetylglutamate kinase 0.46 NOLOHH_03060 2-isopropylmalate synthase low > 57
Escherichia coli ECRC62 0.15 BNILDI_05800 acetylglutamate kinase 0.46 BNILDI_08550 2-isopropylmalate synthase — —
Escherichia coli ECRC99 0.15 KEDOAH_14580 acetylglutamate kinase 0.46 KEDOAH_17440 2-isopropylmalate synthase — —
Escherichia coli BL21 0.15 ECD_03844 acetylglutamate kinase 0.46 ECD_00076 2-isopropylmalate synthase 0.59 36
Escherichia coli ECRC102 0.15 NIAGMN_11330 acetylglutamate kinase 0.46 NIAGMN_08565 2-isopropylmalate synthase — —
Escherichia coli ECRC101 0.15 MCAODC_04080 acetylglutamate kinase 0.46 MCAODC_01230 2-isopropylmalate synthase — —
Escherichia coli ECRC98 0.15 JDDGAC_17205 acetylglutamate kinase 0.46 JDDGAC_14310 2-isopropylmalate synthase — —
Escherichia coli ECRC101 0.15 OKFHMN_13580 acetylglutamate kinase 0.46 OKFHMN_10715 2-isopropylmalate synthase — —
Klebsiella michiganensis M5al 0.15 BWI76_RS00850 acetylglutamate kinase 0.46 BWI76_RS04680 2-isopropylmalate synthase 0.91 14
Escherichia coli ECOR38 0.15 HEPCGN_12225 acetylglutamate kinase 0.46 HEPCGN_08695 2-isopropylmalate synthase low > 85
Enterobacter sp. TBS_079 0.14 MPMX20_04521 Acetylglutamate kinase 0.44 MPMX20_00769 2-isopropylmalate synthase 0.84 43
Enterobacter asburiae PDN3 0.14 EX28DRAFT_4421 N-acetylglutamate kinase (EC 2.7.2.8) 0.45 EX28DRAFT_3670 2-isopropylmalate synthase (EC 2.3.3.13) 0.62 51

Not shown: 11 genomes with orthologs for BT3395 only; 23 genomes with orthologs for BT1861 only