Conservation of cofitness between b2025 and b3772 in Escherichia coli BW25113

69 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2025 hisF imidazole glycerol phosphate synthase subunit HisF (NCBI) 1.0 b3772 ilvA threonine dehydratase (NCBI) 0.94 17
Escherichia coli ECRC98 1.00 JDDGAC_28600 hisF Imidazole glycerol phosphate synthase subunit HisF 1.00 JDDGAC_18255 ilvA threonine ammonia-lyase, biosynthetic
Escherichia coli ECRC101 1.00 MCAODC_20450 hisF Imidazole glycerol phosphate synthase subunit HisF 1.00 MCAODC_05140 ilvA threonine ammonia-lyase, biosynthetic
Escherichia coli ECRC102 1.00 NIAGMN_22435 hisF Imidazole glycerol phosphate synthase subunit HisF 1.00 NIAGMN_12390 ilvA threonine ammonia-lyase, biosynthetic
Escherichia coli ECRC101 1.00 OKFHMN_24490 hisF Imidazole glycerol phosphate synthase subunit HisF 1.00 OKFHMN_14635 ilvA threonine ammonia-lyase, biosynthetic
Escherichia coli ECRC99 1.00 KEDOAH_03660 hisF Imidazole glycerol phosphate synthase subunit HisF 1.00 KEDOAH_13515 ilvA threonine ammonia-lyase, biosynthetic
Escherichia coli ECRC62 1.00 BNILDI_14715 hisF Imidazole glycerol phosphate synthase subunit HisF 1.00 BNILDI_04755 ilvA threonine ammonia-lyase, biosynthetic
Escherichia fergusonii Becca 1.00 EFB2_01831 Imidazole glycerol phosphate synthase subunit HisF 0.99 EFB2_04864 L-threonine dehydratase biosynthetic IlvA low > 86
Escherichia coli Nissle 1917 1.00 ECOLIN_RS11970 imidazole glycerol phosphate synthase subunit HisF 0.99 ECOLIN_RS21670 threonine ammonia-lyase, biosynthetic low > 52
Escherichia coli ECOR27 0.99 NOLOHH_15805 hisF Imidazole glycerol phosphate synthase subunit HisF 1.00 NOLOHH_06770 ilvA threonine ammonia-lyase, biosynthetic low > 57
Escherichia coli ECOR38 0.99 HEPCGN_03195 hisF Imidazole glycerol phosphate synthase subunit HisF 0.99 HEPCGN_13345 ilvA threonine ammonia-lyase, biosynthetic low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01675 Imidazole glycerol phosphate synthase subunit HisF 1.00 OHPLBJKB_04281 L-threonine dehydratase biosynthetic IlvA low > 73
Escherichia coli BL21 0.99 ECD_01927 imidazole glycerol phosphate synthase, catalytic subunit with HisH 1.00 ECD_03650 l-threonine dehydratase, biosynthetic; also known as threonine deaminase
Enterobacter sp. TBS_079 0.97 MPMX20_03007 Imidazole glycerol phosphate synthase subunit HisF 0.93 MPMX20_04498 L-threonine dehydratase biosynthetic IlvA 0.92 20
Enterobacter asburiae PDN3 0.96 EX28DRAFT_0534 imidazoleglycerol phosphate synthase, cyclase subunit 0.93 EX28DRAFT_4444 threonine ammonia-lyase, biosynthetic, long form 0.80 30
Klebsiella michiganensis M5al 0.96 BWI76_RS18950 imidazole glycerol phosphate synthase cyclase subunit 0.94 BWI76_RS00980 PLP-dependent threonine dehydratase 0.86 18
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.95 GFF3907 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.93 GFF2900 Threonine dehydratase biosynthetic (EC 4.3.1.19) low > 78
Serratia liquefaciens MT49 0.95 IAI46_08185 imidazole glycerol phosphate synthase subunit HisF 0.84 IAI46_24340 threonine ammonia-lyase, biosynthetic low > 86
Erwinia tracheiphila SCR3 0.93 LU632_RS08920 hisF imidazole glycerol phosphate synthase subunit HisF 0.83 LU632_RS24395 ilvA threonine ammonia-lyase, biosynthetic low > 74
Dickeya dadantii 3937 0.93 DDA3937_RS09710 imidazole glycerol phosphate synthase subunit HisF 0.86 DDA3937_RS20150 threonine ammonia-lyase, biosynthetic 0.90 20
Dickeya dianthicola 67-19 0.92 HGI48_RS09720 imidazole glycerol phosphate synthase subunit HisF 0.87 HGI48_RS20290 threonine ammonia-lyase, biosynthetic
Dickeya dianthicola ME23 0.92 DZA65_RS10030 imidazole glycerol phosphate synthase subunit HisF 0.85 DZA65_RS21330 threonine ammonia-lyase, biosynthetic 0.86 8
Pectobacterium carotovorum WPP14 0.91 HER17_RS12255 imidazole glycerol phosphate synthase subunit HisF 0.83 HER17_RS01080 threonine ammonia-lyase, biosynthetic 0.94 41
Rahnella sp. WP5 0.91 EX31_RS11465 imidazole glycerol phosphate synthase subunit HisF 0.81 EX31_RS15010 threonine ammonia-lyase, biosynthetic 0.94 44
Pantoea sp. MT58 0.90 IAI47_07065 imidazole glycerol phosphate synthase subunit HisF 0.83 IAI47_01040 threonine ammonia-lyase, biosynthetic 0.98 12
Vibrio cholerae E7946 ATCC 55056 0.87 CSW01_05775 imidazole glycerol phosphate synthase cyclase subunit 0.67 CSW01_00135 threonine ammonia-lyase, biosynthetic low > 62
Shewanella amazonensis SB2B 0.77 Sama_1947 imidazole glycerol phosphate synthase subunit HisF (RefSeq) 0.57 Sama_3278 threonine dehydratase (RefSeq) 0.88 53
Alteromonas macleodii MIT1002 0.76 MIT1002_02638 Imidazole glycerol phosphate synthase subunit HisF 0.54 MIT1002_04040 L-threonine dehydratase biosynthetic IlvA 0.88 51
Shewanella oneidensis MR-1 0.75 SO2068 hisF hisF protein (cyclase) (NCBI ptt file) 0.57 SO4344 ilvA threonine dehydratase (NCBI ptt file) 0.86 70
Shewanella sp. ANA-3 0.75 Shewana3_1848 imidazole glycerol phosphate synthase subunit HisF (RefSeq) 0.56 Shewana3_0359 threonine dehydratase (RefSeq) low > 73
Shewanella loihica PV-4 0.75 Shew_2203 imidazole glycerol phosphate synthase subunit HisF (RefSeq) 0.54 Shew_0293 threonine dehydratase (RefSeq) 0.97 11
Rhodanobacter denitrificans FW104-10B01 0.65 LRK54_RS01580 imidazole glycerol phosphate synthase subunit HisF 0.45 LRK54_RS10300 threonine ammonia-lyase, biosynthetic low > 59
Rhodanobacter denitrificans MT42 0.64 LRK55_RS01360 imidazole glycerol phosphate synthase subunit HisF 0.45 LRK55_RS09940 threonine ammonia-lyase, biosynthetic low > 63
Rhodanobacter sp. FW510-T8 0.64 OKGIIK_04975 hisF imidazole glycerol phosphate synthase subunit HisF 0.46 OKGIIK_13620 ilvA threonine ammonia-lyase, biosynthetic low > 52
Dyella japonica UNC79MFTsu3.2 0.63 ABZR86_RS06705 imidazole glycerol phosphate synthase subunit HisF 0.49 ABZR86_RS15925 threonine ammonia-lyase, biosynthetic low > 74
Brevundimonas sp. GW460-12-10-14-LB2 0.57 A4249_RS10715 imidazole glycerol phosphate synthase subunit HisF 0.49 A4249_RS00615 threonine ammonia-lyase, biosynthetic 0.99 35
Ralstonia solanacearum IBSBF1503 0.43 RALBFv3_RS06815 imidazole glycerol phosphate synthase subunit HisF 0.47 RALBFv3_RS11395 threonine ammonia-lyase, biosynthetic
Ralstonia solanacearum UW163 0.43 UW163_RS06800 imidazole glycerol phosphate synthase subunit HisF 0.47 UW163_RS02190 threonine ammonia-lyase, biosynthetic
Pseudomonas sp. S08-1 0.42 OH686_14595 Imidazole glycerol phosphate synthase cyclase subunit 0.51 OH686_11400 threonine ammonia-lyase, biosynthetic 0.74 14
Ralstonia solanacearum PSI07 0.42 RPSI07_RS10420 imidazole glycerol phosphate synthase subunit HisF 0.50 RPSI07_RS21810 threonine ammonia-lyase, biosynthetic
Ralstonia solanacearum GMI1000 0.42 RS_RS14760 imidazole glycerol phosphate synthase subunit HisF 0.49 RS_RS02225 threonine ammonia-lyase, biosynthetic
Ralstonia sp. UNC404CL21Col 0.42 ABZR87_RS02470 imidazole glycerol phosphate synthase subunit HisF 0.47 ABZR87_RS07360 threonine ammonia-lyase, biosynthetic
Pseudomonas stutzeri RCH2 0.42 Psest_0156 imidazoleglycerol phosphate synthase, cyclase subunit 0.51 Psest_3866 threonine ammonia-lyase, biosynthetic, long form
Cupriavidus basilensis FW507-4G11 0.42 RR42_RS18885 imidazole glycerol phosphate synthase 0.46 RR42_RS02315 threonine dehydratase
Burkholderia phytofirmans PsJN 0.41 BPHYT_RS17680 imidazole glycerol phosphate synthase subunit HisF 0.49 BPHYT_RS11065 threonine dehydratase
Pseudomonas putida KT2440 0.41 PP_0293 Imidazole glycerol phosphate synthase subunit HisF 0.51 PP_3446 threonine deaminase low > 96
Variovorax sp. OAS795 0.41 ABID97_RS23105 imidazole glycerol phosphate synthase subunit HisF 0.50 ABID97_RS07000 threonine ammonia-lyase, biosynthetic
Paraburkholderia graminis OAS925 0.41 ABIE53_003695 cyclase 0.49 ABIE53_002293 threonine dehydratase
Paraburkholderia sabiae LMG 24235 0.40 QEN71_RS27835 imidazole glycerol phosphate synthase subunit HisF 0.49 QEN71_RS01985 threonine ammonia-lyase, biosynthetic 0.93 21
Pseudomonas syringae pv. syringae B728a ΔmexB 0.40 Psyr_4893 imidazole glycerol phosphate synthase subunit hisF 0.49 Psyr_4846 L-threonine ammonia-lyase
Pseudomonas syringae pv. syringae B728a 0.40 Psyr_4893 imidazole glycerol phosphate synthase subunit hisF 0.49 Psyr_4846 L-threonine ammonia-lyase low > 86
Azospirillum sp. SherDot2 0.40 MPMX19_02542 Imidazole glycerol phosphate synthase subunit HisF 0.51 MPMX19_02807 L-threonine dehydratase biosynthetic IlvA
Pseudomonas sp. RS175 0.40 PFR28_04933 Imidazole glycerol phosphate synthase subunit HisF 0.49 PFR28_04834 L-threonine dehydratase biosynthetic IlvA low > 88
Pseudomonas fluorescens FW300-N2E2 0.40 Pf6N2E2_3838 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.50 Pf6N2E2_3938 Threonine dehydratase biosynthetic (EC 4.3.1.19)
Pseudomonas fluorescens SBW25-INTG 0.40 PFLU_RS01625 imidazole glycerol phosphate synthase subunit HisF 0.49 PFLU_RS28665 threonine ammonia-lyase, biosynthetic low > 109
Pseudomonas fluorescens FW300-N1B4 0.40 Pf1N1B4_1623 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.49 Pf1N1B4_2280 Threonine dehydratase biosynthetic (EC 4.3.1.19)
Acinetobacter radioresistens SK82 0.40 MPMX26_02854 Imidazole glycerol phosphate synthase subunit HisF 0.46 MPMX26_01278 L-threonine dehydratase biosynthetic IlvA 0.84 29
Pseudomonas fluorescens FW300-N2E3 0.40 AO353_12090 imidazole glycerol phosphate synthase subunit HisF 0.50 AO353_08485 threonine dehydratase 0.59 57
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_09795 imidazole glycerol phosphate synthase subunit HisF 0.49 AO356_10330 threonine dehydratase 0.54 51
Pseudomonas fluorescens SBW25 0.40 PFLU_RS01625 imidazole glycerol phosphate synthase subunit HisF 0.49 PFLU_RS28665 threonine ammonia-lyase, biosynthetic low > 109
Pseudomonas simiae WCS417 0.40 PS417_01580 imidazole glycerol phosphate synthase 0.49 PS417_27010 threonine dehydratase 0.60 42
Pseudomonas fluorescens GW456-L13 0.40 PfGW456L13_358 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.49 PfGW456L13_949 Threonine dehydratase biosynthetic (EC 4.3.1.19) 0.70 57
Herbaspirillum seropedicae SmR1 0.39 HSERO_RS20315 imidazole glycerol phosphate synthase 0.47 HSERO_RS19510 threonine dehydratase 0.83 15
Marinobacter adhaerens HP15 0.39 HP15_3009 protein containing histidine biosynthesis, HisF domain 0.53 HP15_3213 threonine dehydratase biosynthetic
Variovorax sp. SCN45 0.39 GFF5357 Imidazole glycerol phosphate synthase cyclase subunit 0.51 GFF5246 Threonine dehydratase biosynthetic (EC 4.3.1.19)
Hydrogenophaga sp. GW460-11-11-14-LB1 0.38 GFF1309 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.50 GFF1379 Threonine dehydratase biosynthetic (EC 4.3.1.19)
Dechlorosoma suillum PS 0.38 Dsui_1418 imidazoleglycerol phosphate synthase, cyclase subunit 0.50 Dsui_0728 threonine ammonia-lyase, biosynthetic, long form
Castellaniella sp019104865 MT123 0.37 ABCV34_RS11250 imidazole glycerol phosphate synthase subunit HisF 0.50 ABCV34_RS14460 threonine ammonia-lyase, biosynthetic low > 48
Acidovorax sp. GW101-3H11 0.34 Ac3H11_4733 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.50 Ac3H11_2042 Threonine dehydratase biosynthetic (EC 4.3.1.19)
Phaeobacter inhibens DSM 17395 0.34 PGA1_c09240 imidazole glycerol phosphate synthase subunit HisF 0.18 PGA1_c34900 threonine dehydratase biosynthetic

Not shown: 32 genomes with orthologs for b2025 only; 0 genomes with orthologs for b3772 only