Conservation of cofitness between b0522 and b3642 in Escherichia coli BW25113

67 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0522 purK phosphoribosylaminoimidazole carboxylase (NCBI) 1.0 b3642 pyrE orotate phosphoribosyltransferase (NCBI) 0.89 10
Escherichia coli ECRC62 0.99 BNILDI_22260 purK 5-(carboxyamino)imidazole ribonucleotide synthase 1.00 BNILDI_04035 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECOR38 0.99 HEPCGN_06480 purK 5-(carboxyamino)imidazole ribonucleotide synthase 1.00 HEPCGN_14420 pyrE Orotate phosphoribosyltransferase low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_03159 N5-carboxyaminoimidazole ribonucleotide synthase 1.00 OHPLBJKB_00060 Orotate phosphoribosyltransferase low > 73
Escherichia coli BL21 0.99 ECD_00472 N5-carboxyaminoimidazole ribonucleotide synthase 1.00 ECD_03499 orotate phosphoribosyltransferase 0.70 8
Escherichia coli ECOR27 0.99 NOLOHH_00830 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.99 NOLOHH_07480 pyrE Orotate phosphoribosyltransferase low > 57
Escherichia coli ECRC101 0.98 OKFHMN_07840 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.99 OKFHMN_15600 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli Nissle 1917 0.98 ECOLIN_RS03025 5-(carboxyamino)imidazole ribonucleotide synthase 1.00 ECOLIN_RS20750 orotate phosphoribosyltransferase low > 52
Escherichia coli ECRC99 0.98 KEDOAH_20130 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.99 KEDOAH_12550 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECRC102 0.98 NIAGMN_05895 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.99 NIAGMN_13360 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECRC101 0.98 MCAODC_27060 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.99 MCAODC_06110 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECRC98 0.98 JDDGAC_11490 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.99 JDDGAC_19225 pyrE Orotate phosphoribosyltransferase — —
Escherichia fergusonii Becca 0.98 EFB2_03540 N5-carboxyaminoimidazole ribonucleotide synthase 1.00 EFB2_00171 Orotate phosphoribosyltransferase low > 86
Enterobacter asburiae PDN3 0.90 EX28DRAFT_2460 phosphoribosylaminoimidazole carboxylase, PurK protein 0.96 EX28DRAFT_3892 orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Klebsiella michiganensis M5al 0.90 BWI76_RS07065 5-(carboxyamino)imidazole ribonucleotide synthase 0.96 BWI76_RS27385 orotate phosphoribosyltransferase 0.69 66
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.89 GFF4438 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.97 GFF367 Orotate phosphoribosyltransferase (EC 2.4.2.10) low > 78
Enterobacter sp. TBS_079 0.87 MPMX20_01097 N5-carboxyaminoimidazole ribonucleotide synthase 0.94 MPMX20_00093 Orotate phosphoribosyltransferase 0.77 51
Pantoea sp. MT58 0.81 IAI47_14355 5-(carboxyamino)imidazole ribonucleotide synthase 0.87 IAI47_00600 orotate phosphoribosyltransferase 0.95 8
Rahnella sp. WP5 0.79 EX31_RS22620 5-(carboxyamino)imidazole ribonucleotide synthase 0.90 EX31_RS14500 orotate phosphoribosyltransferase 0.87 56
Dickeya dianthicola 67-19 0.78 HGI48_RS15190 5-(carboxyamino)imidazole ribonucleotide synthase 0.88 HGI48_RS00680 orotate phosphoribosyltransferase 0.59 45
Pectobacterium carotovorum WPP14 0.78 HER17_RS06470 5-(carboxyamino)imidazole ribonucleotide synthase 0.90 HER17_RS20850 orotate phosphoribosyltransferase 0.96 11
Dickeya dianthicola ME23 0.77 DZA65_RS15995 5-(carboxyamino)imidazole ribonucleotide synthase 0.88 DZA65_RS00735 orotate phosphoribosyltransferase 0.64 37
Erwinia tracheiphila SCR3 0.77 LU632_RS15250 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.88 LU632_RS22015 pyrE orotate phosphoribosyltransferase 0.78 14
Dickeya dadantii 3937 0.77 DDA3937_RS15110 5-(carboxyamino)imidazole ribonucleotide synthase 0.90 DDA3937_RS20535 orotate phosphoribosyltransferase 0.85 10
Serratia liquefaciens MT49 0.74 IAI46_05370 5-(carboxyamino)imidazole ribonucleotide synthase 0.91 IAI46_24845 orotate phosphoribosyltransferase 0.76 25
Shewanella oneidensis MR-1 0.48 SO3555 purK phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI ptt file) 0.82 SO4255 pyrE orotate phosphoribosyltransferase (NCBI ptt file) 0.87 40
Shewanella amazonensis SB2B 0.48 Sama_1063 phosphoribosylaminoimidazole carboxylase ATPase subunit (RefSeq) 0.84 Sama_0321 pyrE orotate phosphoribosyltransferase (RefSeq) low > 62
Shewanella sp. ANA-3 0.48 Shewana3_3156 phosphoribosylaminoimidazole carboxylase ATPase subunit (RefSeq) 0.82 Shewana3_3776 pyrE orotate phosphoribosyltransferase (RefSeq) 0.82 66
Alteromonas macleodii MIT1002 0.31 MIT1002_00522 N5-carboxyaminoimidazole ribonucleotide synthase 0.75 MIT1002_04070 Orotate phosphoribosyltransferase — —
Vibrio cholerae E7946 ATCC 55056 0.30 CSW01_00260 5-(carboxyamino)imidazole ribonucleotide synthase 0.85 CSW01_01120 orotate phosphoribosyltransferase 0.52 37
Pseudomonas putida KT2440 0.30 PP_5335 N5-carboxyaminoimidazole ribonucleotide synthase 0.67 PP_5291 Orotate phosphoribosyltransferase — —
Marinobacter adhaerens HP15 0.30 HP15_2350 phosphoribosylaminoimidazole carboxylase ATPase subunit 0.64 HP15_298 orotate phosphoribosyltransferase — —
Acinetobacter radioresistens SK82 0.30 MPMX26_03050 N5-carboxyaminoimidazole ribonucleotide synthase 0.56 MPMX26_02937 Orotate phosphoribosyltransferase 0.83 20
Pseudomonas stutzeri RCH2 0.29 Psest_4068 phosphoribosylaminoimidazole carboxylase, PurK protein 0.71 Psest_3810 orotate phosphoribosyltransferase — —
Pseudomonas sp. RS175 0.29 PFR28_04495 N5-carboxyaminoimidazole ribonucleotide synthase 0.71 PFR28_04417 Orotate phosphoribosyltransferase — —
Pseudomonas fluorescens FW300-N2E2 0.29 Pf6N2E2_4081 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.68 Pf6N2E2_4370 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Pseudomonas fluorescens GW456-L13 0.29 PfGW456L13_747 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.67 PfGW456L13_788 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Pseudomonas fluorescens FW300-N2C3 0.29 AO356_11075 phosphoribosylaminoimidazole carboxylase 0.67 AO356_12520 orotate phosphoribosyltransferase — —
Pseudomonas simiae WCS417 0.29 PS417_28115 phosphoribosylaminoimidazole carboxylase 0.68 PS417_27795 orotate phosphoribosyltransferase — —
Pseudomonas sp. S08-1 0.28 OH686_13380 N5-carboxyaminoimidazole ribonucleotide synthase 0.69 OH686_13590 Orotate phosphoribosyltransferase — —
Pseudomonas fluorescens SBW25 0.28 PFLU_RS29800 5-(carboxyamino)imidazole ribonucleotide synthase 0.68 PFLU_RS29475 orotate phosphoribosyltransferase — —
Pseudomonas fluorescens FW300-N2E3 0.28 AO353_09935 phosphoribosylaminoimidazole carboxylase 0.67 AO353_09245 orotate phosphoribosyltransferase — —
Pseudomonas fluorescens SBW25-INTG 0.28 PFLU_RS29800 5-(carboxyamino)imidazole ribonucleotide synthase 0.68 PFLU_RS29475 orotate phosphoribosyltransferase — —
Pseudomonas fluorescens FW300-N1B4 0.28 Pf1N1B4_2028 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.67 Pf1N1B4_2120 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.28 Psyr_5047 5-(carboxyamino)imidazole ribonucleotide synthase 0.72 Psyr_0216 orotate phosphoribosyltransferase — —
Pseudomonas syringae pv. syringae B728a 0.28 Psyr_5047 5-(carboxyamino)imidazole ribonucleotide synthase 0.72 Psyr_0216 orotate phosphoribosyltransferase — —
Xanthomonas campestris pv. campestris strain 8004 0.27 Xcc-8004.2012.1 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.47 Xcc-8004.4884.1 Orotate phosphoribosyltransferase (EC 2.4.2.10) low > 74
Kangiella aquimarina DSM 16071 0.27 B158DRAFT_0610 5-(carboxyamino)imidazole ribonucleotide synthase 0.70 B158DRAFT_0786 orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Shewanella loihica PV-4 0.26 Shew_1249 phosphoribosylaminoimidazole carboxylase, ATPase subunit (RefSeq) 0.83 Shew_3487 pyrE orotate phosphoribosyltransferase (RefSeq) 0.65 54
Lysobacter sp. OAE881 0.25 ABIE51_RS15390 5-(carboxyamino)imidazole ribonucleotide synthase 0.46 ABIE51_RS00065 orotate phosphoribosyltransferase 0.65 2
Rhodanobacter sp. FW510-T8 0.25 OKGIIK_03050 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.59 OKGIIK_15685 pyrE orotate phosphoribosyltransferase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.24 GFF2770 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.49 GFF1882 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Variovorax sp. SCN45 0.24 GFF5513 N5-carboxyaminoimidazole ribonucleotide synthase (EC 6.3.4.18) 0.49 GFF5065 Orotate phosphoribosyltransferase (EC 2.4.2.10) low > 127
Rhodanobacter denitrificans FW104-10B01 0.24 LRK54_RS13815 5-(carboxyamino)imidazole ribonucleotide synthase 0.59 LRK54_RS09190 orotate phosphoribosyltransferase — —
Rhodanobacter denitrificans MT42 0.24 LRK55_RS13530 5-(carboxyamino)imidazole ribonucleotide synthase 0.59 LRK55_RS08720 orotate phosphoribosyltransferase low > 63
Dyella japonica UNC79MFTsu3.2 0.23 ABZR86_RS09830 5-(carboxyamino)imidazole ribonucleotide synthase 0.61 ABZR86_RS15640 orotate phosphoribosyltransferase — —
Herbaspirillum seropedicae SmR1 0.22 HSERO_RS03370 phosphoribosylaminoimidazole carboxylase 0.55 HSERO_RS23380 orotate phosphoribosyltransferase — —
Variovorax sp. OAS795 0.22 ABID97_RS01700 5-(carboxyamino)imidazole ribonucleotide synthase 0.48 ABID97_RS03910 orotate phosphoribosyltransferase — —
Acidovorax sp. GW101-3H11 0.21 Ac3H11_675 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.51 Ac3H11_3341 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Dechlorosoma suillum PS 0.20 Dsui_0091 phosphoribosylaminoimidazole carboxylase, PurK protein 0.58 Dsui_0873 orotate phosphoribosyltransferase — —
Castellaniella sp019104865 MT123 0.20 ABCV34_RS00565 5-(carboxyamino)imidazole ribonucleotide synthase 0.58 ABCV34_RS10890 orotate phosphoribosyltransferase — —
Bifidobacterium breve UCC2003 0.19 BBR_RS13300 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 BBR_RS15455 orotate phosphoribosyltransferase low > 34
Cupriavidus basilensis FW507-4G11 0.19 RR42_RS03230 phosphoribosylaminoimidazole carboxylase 0.55 RR42_RS01225 orotate phosphoribosyltransferase — —
Ralstonia solanacearum GMI1000 0.18 RS_RS02885 5-(carboxyamino)imidazole ribonucleotide synthase 0.52 RS_RS00685 orotate phosphoribosyltransferase — —
Ralstonia sp. UNC404CL21Col 0.17 ABZR87_RS08090 5-(carboxyamino)imidazole ribonucleotide synthase 0.52 ABZR87_RS05590 orotate phosphoribosyltransferase — —
Ralstonia solanacearum UW163 0.17 UW163_RS01410 5-(carboxyamino)imidazole ribonucleotide synthase 0.53 UW163_RS03505 orotate phosphoribosyltransferase — —
Ralstonia solanacearum IBSBF1503 0.17 RALBFv3_RS12200 5-(carboxyamino)imidazole ribonucleotide synthase 0.53 RALBFv3_RS10075 orotate phosphoribosyltransferase — —
Ralstonia solanacearum PSI07 0.17 RPSI07_RS21130 5-(carboxyamino)imidazole ribonucleotide synthase 0.52 RPSI07_RS23295 orotate phosphoribosyltransferase — —

Not shown: 25 genomes with orthologs for b0522 only; 3 genomes with orthologs for b3642 only