| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1126 | | Two-component system regulatory protein | insig. | 100 | 100 |
| o | Pseudomonas fluorescens FW300-N2C3 | AO356_26255 | | chemotaxis protein CheY | insig. | 98 | 100 |
| o | Pseudomonas sp. RS175 | PFR28_01866 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 99 | 97 |
| o | Pseudomonas syringae pv. syringae B728a | Psyr_1938 | | Response regulator receiver | insig. | 89 | 98 |
| o | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1938 | | Response regulator receiver | insig. | 89 | 98 |
| o | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_5054 | | Two-component system regulatory protein | insig. | 88 | 97 |
| o | Pseudomonas lactucae CFBP13502 | GEMAOFIL_03211 | | Regulatory protein AtoC | no data | 85 | 99 |
| o | Methylophilus sp. DMC18 | GFF421 | | Response regulator PleD | insig. | 56 | 90 |
| o | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.4233.1 | | two-component system sensor protein | insig. | 53 | 85 |
| | Azospirillum sp. SherDot2 | MPMX19_01591 | | Sensor histidine kinase RcsC | insig. | 40 | 83 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS00885 | | chemotaxis protein CheY | insig. | 41 | 85 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_29820 | | phosphohydrolase | insig. | 39 | 95 |
| | Pseudomonas sp. RS175 | PFR28_01438 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 40 | 88 |
| | Azospirillum brasilense Sp245 | AZOBR_RS14285 | | transcriptional regulator | strong | 37 | 90 |
| | Azospirillum sp. SherDot2 | MPMX19_01958 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 38 | 90 |
| | Bosea sp. OAE506 | ABIE41_RS11550 | | HD domain-containing phosphohydrolase | insig. | 36 | 85 |
| | Azospirillum sp. SherDot2 | MPMX19_01957 | | Sensor histidine kinase RcsC | insig. | 40 | 85 |
| | Azospirillum brasilense Sp245 | AZOBR_RS16180 | | diguanylate cyclase | strong | 34 | 87 |
| | Shewanella loihica PV-4 | Shew_0981 | | response regulator receiver protein (RefSeq) | insig. | 36 | 78 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS06195 | | transcriptional regulator | insig. | 32 | 93 |
| | Azospirillum sp. SherDot2 | MPMX19_01522 | | Response regulator PleD | insig. | 35 | 87 |
| | Alteromonas macleodii MIT1002 | MIT1002_01320 | | Alkaline phosphatase synthesis transcriptional regulatory protein PhoP | cofit | 33 | 85 |
| | Azospirillum brasilense Sp245 | AZOBR_RS14305 | | transcriptional regulator | cofit | 36 | 83 |
| | Azospirillum sp. SherDot2 | MPMX19_00501 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 34 | 91 |
| | Agrobacterium fabrum C58 | Atu1297 | | two component response regulator | insig. | 33 | 83 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_03092 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 35 | 91 |
| | Dechlorosoma suillum PS | Dsui_1863 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | insig. | 36 | 86 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS03815 | | hybrid sensor histidine kinase/response regulator | cofit | 37 | 85 |
| | Rhodopseudomonas palustris CGA009 | TX73_000745 | | response regulator | insig. | 33 | 85 |
| | Lysobacter sp. OAE881 | ABIE51_RS00635 | | hybrid sensor histidine kinase/response regulator | strong | 38 | 74 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1098 | | response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) | insig. | 36 | 83 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1098 | | response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) | insig. | 36 | 83 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS10535 | | response regulator | strong | 31 | 84 |
| | Sphingobium sp. HT1-2 | GFF2748 | | Pole remodelling regulatory diguanylate cyclase | cofit | 32 | 92 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS15265 | | EAL domain-containing response regulator | insig. | 38 | 76 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS15265 | | EAL domain-containing response regulator | insig. | 38 | 76 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS08635 | | response regulator | sig. | 34 | 78 |
| | Azospirillum sp. SherDot2 | MPMX19_05749 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 36 | 85 |
| | Rhodopseudomonas palustris CGA009 | TX73_016195 | | PleD family two-component system response regulator | insig. | 33 | 83 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS06585 | | response regulator | cofit | 30 | 84 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS10415 | | SpoIIE family protein phosphatase | insig. | 35 | 92 |
| | Sinorhizobium meliloti 1021 | SMc01370 | | response regulator PleD | insig. | 35 | 94 |
| | Shewanella amazonensis SB2B | Sama_1718 | | response regulator receiver protein (RefSeq) | strong | 38 | 76 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1453 | rpaB | two component transcriptional regulator, winged helix family | no data | 34 | 91 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4346 | | Signal transduction histidine kinase | insig. | 33 | 89 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2200 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | no data | 30 | 87 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS08895 | | response regulator | insig. | 30 | 99 |
| | Pseudomonas sp. S08-1 | OH686_23615 | | Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY | insig. | 40 | 76 |
| | Pseudomonas sp. RS175 | PFR28_04227 | | Sensor histidine kinase RcsC | insig. | 38 | 70 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_13500 | | histidine kinase | sig. | 37 | 70 |
| | Shewanella sp. ANA-3 | Shewana3_4015 | | response regulator receiver modulated diguanylate cyclase (RefSeq) | cofit | 33 | 75 |
| | Dechlorosoma suillum PS | Dsui_2382 | | PAS domain S-box | cofit | 33 | 81 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS03320 | | EAL domain-containing protein | insig. | 31 | 88 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS02280 | | hybrid sensor histidine kinase/response regulator | cofit | 35 | 71 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_03695 | | Histidine kinase | insig. | 34 | 78 |
| | Dechlorosoma suillum PS | Dsui_0331 | | PAS domain S-box | insig. | 37 | 83 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_4617 | | Signal transduction histidine kinase CheA (EC 2.7.3.-) | strong | 37 | 70 |
| | Rhizobium sp. OAE497 | ABIE40_RS07330 | | PleD family two-component system response regulator | cofit | 33 | 83 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS21455 | | PleD family two-component system response regulator | no data | 41 | 69 |
| | Dinoroseobacter shibae DFL-12 | Dshi_2820 | | response regulator receiver modulated diguanylate cyclase (RefSeq) | sig. | 33 | 77 |
| | Shewanella loihica PV-4 | Shew_0979 | | response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) (RefSeq) | insig. | 31 | 86 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS17390 | | two-component system response regulator | insig. | 35 | 77 |
| | Rhodospirillum rubrum S1H | Rru_A2929 | | Two component Transcriptional regulator, Winged helix family (NCBI) | cofit | 36 | 79 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS10705 | | response regulator | insig. | 34 | 81 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS09310 | | two-component system response regulator | insig. | 35 | 83 |
| | Caulobacter crescentus NA1000 | CCNA_02546 | | GGDEF/response regulator protein PleD | strong | 32 | 84 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02546 | | GGDEF/response regulator protein PleD | cofit | 32 | 84 |
| | Dechlorosoma suillum PS | Dsui_3468 | | Response regulator receiver domain protein,histidine kinase | cofit | 31 | 89 |
| | Dechlorosoma suillum PS | Dsui_3334 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein | cofit | 36 | 91 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS12170 | | response regulator | insig. | 32 | 84 |
| | Pseudomonas sp. BP01 | JOY50_RS23150 | | diguanylate cyclase | insig. | 36 | 76 |
| | Pseudomonas putida KT2440 | PP_0563 | | Response regulator | insig. | 36 | 76 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_01420 | | Histidine kinase | cofit | 37 | 75 |
| | Bosea sp. OAE506 | ABIE41_RS00505 | | HAMP domain-containing protein | insig. | 36 | 74 |
| | Phaeobacter inhibens DSM 17395 | PGA1_262p02130 | | response regulator receiver | insig. | 36 | 69 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_03275 | | hybrid sensor histidine kinase/response regulator | insig. | 35 | 74 |
| | Azospirillum sp. SherDot2 | MPMX19_02025 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 34 | 77 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_03989 | | PAS domain S-box protein | insig. | 32 | 74 |
| | Marinobacter adhaerens HP15 | HP15_1054 | | multi-sensor signal transduction histidine kinase | strong | 30 | 77 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS16770 | | hybrid sensor histidine kinase/response regulator | insig. | 40 | 72 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2898.1 | | Sensory/regulatory protein rpfC (EC 2.7.3.-) | strong | 37 | 70 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS18990 | | response regulator | insig. | 36 | 75 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_08085 | | histidine kinase | strong | 36 | 70 |
| | Pseudomonas sp. SVBP6 | COO64_RS13630 | | Hpt domain-containing protein | cofit | 35 | 70 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_0492 | | Response regulator receiver:CheW-like protein:ATP-binding region, ATPase-like:Hpt | insig. | 34 | 75 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_0492 | | Response regulator receiver:CheW-like protein:ATP-binding region, ATPase-like:Hpt | insig. | 34 | 75 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1461 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | no data | 34 | 94 |
| | Acinetobacter radioresistens SK82 | MPMX26_02509 | | Sensor histidine kinase RcsC | cofit | 34 | 77 |
| | Rhodospirillum rubrum S1H | Rru_A0603 | | Two component Transcriptional regulator, Winged helix family (NCBI) | cofit | 35 | 95 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS20605 | | response regulator | insig. | 32 | 94 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS06810 | | response regulator | insig. | 34 | 77 |
| | Azospirillum sp. SherDot2 | MPMX19_01858 | | Alkaline phosphatase synthesis transcriptional regulatory protein PhoP | insig. | 39 | 81 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2888.1 | | Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) | insig. | 39 | 68 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0366 | | two-component system sensor histidine kinase/response regulator, hybrid ('one component system') (NCBI ptt file) | sig. | 34 | 82 |
| | Xanthobacter sp. DMC5 | GFF1825 | | Sensor histidine kinase RcsC | insig. | 33 | 75 |
| | Shewanella sp. ANA-3 | Shewana3_2212 | | response regulator receiver modulated diguanylate cyclase (RefSeq) | insig. | 39 | 68 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS28295 | | response regulator | insig. | 37 | 70 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS28295 | | response regulator | sig. | 37 | 70 |
| | Pseudomonas simiae WCS417 | PS417_26650 | | histidine kinase | strong | 37 | 70 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2618 | | sensory box histidine kinase/response regulator | insig. | 36 | 72 |