| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Enterobacter sp. TBS_079 | MPMX20_03199 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 100 | 100 |
| o | Enterobacter asburiae PDN3 | EX28DRAFT_0341 | | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase | insig. | 81 | 100 |
| o | Escherichia fergusonii Becca | EFB2_01592 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 70 | 98 |
| o | Escherichia coli Nissle 1917 | ECOLIN_RS13180 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | no data | 69 | 98 |
| o | Escherichia coli ECRC62 | BNILDI_13480 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | cofit | 70 | 98 |
| o | Escherichia coli ECRC100 | OKFHMN_22940 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | insig. | 69 | 98 |
| o | Escherichia coli ECRC101 | MCAODC_13980 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | insig. | 69 | 98 |
| o | Escherichia coli ECRC102 | NIAGMN_20710 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | insig. | 69 | 98 |
| o | Escherichia coli ECRC98 | JDDGAC_26905 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | insig. | 69 | 98 |
| o | Escherichia coli ECRC99 | KEDOAH_05255 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | no data | 69 | 98 |
| o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01447 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 69 | 98 |
| o | Escherichia coli BL21 | ECD_02190 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 69 | 98 |
| o | Escherichia coli BW25113 | b2263 | yfbB | predicted peptidase (NCBI) | sig. | 69 | 98 |
| o | Escherichia coli ECOR27 | NOLOHH_14565 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | insig. | 69 | 98 |
| o | Escherichia coli ECOR38 | HEPCGN_22155 | menH | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | insig. | 68 | 98 |
| o | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF1869 | | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate synthase (EC 4.2.99.20) | insig. | 65 | 98 |
| o | Klebsiella michiganensis M5al | BWI76_RS20070 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | no data | 62 | 97 |
| o | Klebsiella pneumoniae MKP103 | KDGMDA_26985 | | 2-succinyl-6-hydroxy-2 4-cyclohexadiene-1-carboxylate synthase | insig. | 61 | 97 |
| o | Dickeya dadantii 3937 | DDA3937_RS05920 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 51 | 93 |
| o | Dickeya dianthicola 67-19 | HGI48_RS05965 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 51 | 93 |
| o | Dickeya dianthicola ME23 | DZA65_RS06300 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | cofit | 51 | 93 |
| o | Pectobacterium carotovorum WPP14 | HER17_RS15550 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 47 | 96 |
| o | Serratia liquefaciens MT49 | IAI46_17555 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 46 | 97 |
| o | Rahnella sp. WP5 | EX31_RS19350 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 50 | 89 |
| o | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_18175 | menH | 2-succinyl-6-hydroxy-2 4-cyclohexadiene-1-carboxylate synthase | cofit | 45 | 91 |
| o | Erwinia tracheiphila SCR3 | LU632_RS08110 | menH | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 45 | 91 |
| o | Vibrio cholerae E7946 ATCC 55056 | CSW01_09855 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 42 | 89 |
| o | Shewanella amazonensis SB2B | Sama_3461 | | alpha/beta fold family hydrolase (RefSeq) | strong | 39 | 92 |
| o | Shewanella sp. ANA-3 | Shewana3_3966 | | alpha/beta hydrolase fold (RefSeq) | strong | 36 | 99 |
| o | Shewanella loihica PV-4 | Shew_3600 | | alpha/beta hydrolase fold (RefSeq) | cofit | 39 | 88 |
| o | Shewanella oneidensis MR-1 | SO4574 | | hydrolase, alpha/beta fold family (NCBI ptt file) | strong | 35 | 98 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS19270 | | alpha/beta fold hydrolase | insig. | 27 | 91 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_05864 | | Pimeloyl-ACP methyl ester carboxylesterase | insig. | 27 | 93 |
| o | Agrobacterium fabrum C58 | Atu2061 | | hydrolase | insig. | 24 | 97 |
| o | Castellaniella sp019104865 MT123 | ABCV34_RS00720 | | alpha/beta hydrolase | insig. | 29 | 94 |
| | Acinetobacter radioresistens SK82 | MPMX26_01706 | | Esterase YbfF | insig. | 30 | 41 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS05315 | | hydrolase | insig. | 27 | 95 |
| | Paraburkholderia graminis OAS925 | ABIE53_006194 | | 3-oxoadipate enol-lactonase | sig. | 28 | 92 |
| | Klebsiella michiganensis M5al | BWI76_RS03330 | | putative hydrolase | insig. | 27 | 94 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF605 | | Biotin synthesis protein BioH | insig. | 27 | 90 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02641 | | Dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system | cofit | 37 | 37 |
| | Pseudomonas sp. RS175 | PFR28_01771 | | Dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system | insig. | 36 | 39 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS04775 | | alpha/beta hydrolase | strong | 28 | 91 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_18845 | | alpha/beta hydrolase | sig. | 26 | 70 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_0662 | | Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) | strong | 23 | 93 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_05865 | | alpha/beta hydrolase | insig. | 31 | 55 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS29350 | | acetoin dehydrogenase | no data | 38 | 35 |
| | Pantoea sp. MT58 | IAI47_01790 | | pimeloyl-ACP methyl ester esterase BioH | insig. | 36 | 38 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c33780 | | putative alpha / beta fold hydrolase | insig. | 26 | 86 |
| | Cellulophaga baltica 18 | M666_RS07985 | | alpha/beta fold hydrolase | insig. | 29 | 39 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS14125 | | acetoin dehydrogenase dihydrolipoyllysine-residue acetyltransferase subunit | insig. | 36 | 36 |
| | Cellulophaga baltica 18 | M666_RS13105 | | alpha/beta hydrolase | insig. | 33 | 32 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_21380 | | acetoin dehydrogenase dihydrolipoyllysine-residue acetyltransferase subunit | insig. | 36 | 34 |
| | Pectobacterium carotovorum WPP14 | HER17_RS01555 | | pimeloyl-ACP methyl ester esterase BioH | cofit | 28 | 87 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0866 | | putative pimeloyl-BioC--CoA transferase BioH | no data | 25 | 86 |
| | Klebsiella michiganensis M5al | BWI76_RS26630 | | pimeloyl-[acyl-carrier protein] methyl ester esterase | sig. | 27 | 91 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_25150 | | acetoin dehydrogenase | insig. | 35 | 39 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_24890 | | acetoin dehydrogenase | insig. | 35 | 39 |
| | Dickeya dadantii 3937 | DDA3937_RS19645 | | pimeloyl-ACP methyl ester esterase BioH | insig. | 28 | 87 |
| | Dickeya dianthicola 67-19 | HGI48_RS19775 | | pimeloyl-ACP methyl ester esterase BioH | no data | 28 | 87 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_07015 | | pimeloyl-ACP methyl ester esterase BioH | insig. | 33 | 38 |
| | Rahnella sp. WP5 | EX31_RS20645 | | alpha/beta hydrolase | insig. | 28 | 91 |
| | Marinobacter adhaerens HP15 | HP15_3229 | | abhydrolase domain-containing protein 6 | strong | 28 | 36 |
| | Rhodopseudomonas palustris CGA009 | TX73_008055 | | alpha/beta hydrolase | insig. | 27 | 94 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c11820 | | putative esterase | strong | 26 | 41 |
| | Pseudomonas sp. SVBP6 | COO64_RS18335 | | acetoin dehydrogenase dihydrolipoyllysine-residue acetyltransferase subunit | insig. | 34 | 38 |
| | Variovorax sp. OAS795 | ABID97_RS26545 | | alpha/beta fold hydrolase | strong | 28 | 90 |
| | Dickeya dianthicola ME23 | DZA65_RS20865 | | pimeloyl-ACP methyl ester esterase BioH | insig. | 28 | 86 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS18310 | | pimeloyl-ACP methyl ester esterase BioH | cofit | 36 | 38 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_667 | | Dihydrolipoamide acetyltransferase component (E2) of acetoin dehydrogenase complex (EC 2.3.1.-) | insig. | 34 | 39 |
| | Erwinia amylovora T8 | OLJFJH_17045 | | esterase | insig. | 34 | 35 |
| | Dechlorosoma suillum PS | Dsui_3019 | | putative hydrolase or acyltransferase of alpha/beta superfamily | insig. | 34 | 38 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02001 | | 2-(acetamidomethylene)succinate hydrolase | cofit | 33 | 45 |
| | Alteromonas macleodii MIT1002 | MIT1002_02290 | | Esterase YbfF | insig. | 29 | 36 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_13715 | | pimeloyl-[acyl-carrier protein] methyl ester esterase | insig. | 26 | 75 |
| | Caulobacter crescentus NA1000 | CCNA_03841 | | alpha/beta hydrolase family protein | cofit | 32 | 36 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_03841 | | alpha/beta hydrolase family protein | insig. | 32 | 36 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_6035 | | alpha/beta hydrolase fold | insig. | 36 | 36 |
| | Serratia liquefaciens MT49 | IAI46_23825 | | pimeloyl-ACP methyl ester esterase BioH | insig. | 32 | 38 |
| | Marinobacter adhaerens HP15 | HP15_2802 | | alpha/beta hydrolase fold protein | insig. | 29 | 47 |
| | Methylophilus sp. DMC18 | GFF1891 | | Esterase YbfF | insig. | 28 | 41 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_0774 | | esterase | strong | 27 | 89 |
| | Pseudomonas putida KT2440 | PP_0553 | | Dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system | strong | 35 | 36 |
| | Azospirillum brasilense Sp245 | AZOBR_RS04805 | | dihydrolipoyllysine acetyltransferase | insig. | 35 | 34 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS02320 | | 3-oxoadipate enol-lactonase | insig. | 30 | 51 |
| | Pseudomonas sp. BP01 | JOY50_RS23100 | | acetoin dehydrogenase dihydrolipoyllysine-residue acetyltransferase subunit | insig. | 34 | 36 |
| | Pseudomonas sp. BP01 | JOY50_RS13035 | | alpha/beta fold hydrolase | insig. | 32 | 41 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS06460 | | alpha/beta hydrolase | insig. | 33 | 37 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS19710 | | hydrolase | insig. | 24 | 95 |
| | Azospirillum brasilense Sp245 | AZOBR_RS21585 | | alpha/beta hydrolase | insig. | 40 | 33 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS10705 | | alpha/beta hydrolase | cofit | 31 | 42 |
| | Rhizobium sp. OAE497 | ABIE40_RS21310 | | alpha/beta hydrolase | insig. | 30 | 81 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_1917 | | pyrimidine utilization protein D | cofit | 30 | 38 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_15290 | | alpha/beta hydrolase | sig. | 30 | 37 |
| | Shewanella sp. ANA-3 | Shewana3_2471 | | alpha/beta fold family hydrolase (RefSeq) | insig. | 26 | 93 |
| | Dechlorosoma suillum PS | Dsui_2819 | | putative hydrolase or acyltransferase of alpha/beta superfamily | cofit | 32 | 52 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS02345 | | alpha/beta hydrolase | insig. | 30 | 42 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2240 | | Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) | insig. | 27 | 92 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS37525 | | alpha/beta hydrolase | insig. | 24 | 91 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_4130 | | pimelyl-[acyl-carrier protein] methyl ester esterase | cofit | 34 | 38 |