| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Methanococcus maripaludis S2 | MMP_RS07530 | | 4Fe-4S binding protein | strong | 100 | 100 |
| o | Methanococcus maripaludis JJ | MMJJ_RS06830 | | 4Fe-4S binding protein | sig. | 96 | 100 |
| | Methanococcus maripaludis JJ | MMJJ_RS06825 | | 4Fe-4S binding protein | sig. | 31 | 98 |
| | Methanococcus maripaludis S2 | MMP_RS07535 | | 4Fe-4S binding protein | strong | 30 | 98 |
| | Methanococcus maripaludis S2 | MMP_RS07535 | | 4Fe-4S binding protein | strong | 34 | 82 |
| | Methanococcus maripaludis JJ | MMJJ_RS06825 | | 4Fe-4S binding protein | sig. | 33 | 82 |
| | Methanococcus maripaludis JJ | MMJJ_RS07945 | | 4Fe-4S binding protein | strong | 33 | 85 |
| | Methanococcus maripaludis JJ | MMJJ_RS05645 | | 4Fe-4S binding protein | sig. | 34 | 77 |
| | Methanococcus maripaludis S2 | MMP_RS08720 | | 4Fe-4S binding protein | strong | 34 | 77 |
| | Methanococcus maripaludis S2 | MMP_RS06405 | | 4Fe-4S binding protein | no data | 32 | 85 |
| | Methanococcus maripaludis JJ | MMJJ_RS04865 | | 4Fe-4S binding protein | cofit | 33 | 96 |
| | Methanococcus maripaludis JJ | MMJJ_RS06835 | | 4Fe-4S binding protein | strong | 33 | 76 |
| | Methanococcus maripaludis JJ | MMJJ_RS07945 | | 4Fe-4S binding protein | strong | 32 | 76 |
| | Methanococcus maripaludis S2 | MMP_RS06405 | | 4Fe-4S binding protein | no data | 32 | 76 |
| | Methanococcus maripaludis S2 | MMP_RS00620 | | 4Fe-4S binding protein | strong | 34 | 96 |
| | Methanococcus maripaludis S2 | MMP_RS07525 | | 4Fe-4S binding protein | strong | 33 | 76 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS15125 | | Fe-S cluster domain-containing protein | no data | 33 | 75 |
| | Methanococcus maripaludis JJ | MMJJ_RS06025 | | 4Fe-4S binding protein | strong | 30 | 84 |
| | Methanococcus maripaludis JJ | MMJJ_RS04865 | | 4Fe-4S binding protein | cofit | 27 | 80 |
| | Methanococcus maripaludis S2 | MMP_RS00620 | | 4Fe-4S binding protein | strong | 27 | 80 |
| | Methanococcus maripaludis JJ | MMJJ_RS00860 | | 4Fe-4S binding protein | insig. | 30 | 78 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS20105 | | Fe-S cluster domain-containing protein | strong | 34 | 76 |
| | Methanococcus maripaludis JJ | MMJJ_RS06025 | | 4Fe-4S binding protein | strong | 30 | 92 |
| | Methanococcus maripaludis S2 | MMP_RS08720 | | 4Fe-4S binding protein | strong | 34 | 81 |
| | Methanococcus maripaludis S2 | MMP_RS08345 | | 4Fe-4S binding protein | strong | 29 | 84 |
| | Methanococcus maripaludis S2 | MMP_RS04290 | | 4Fe-4S binding protein | sig. | 29 | 78 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3805 | | Iron-sulfur cluster-binding protein | sig. | 34 | 61 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS06345 | | Fe-S cluster domain-containing protein | strong | 33 | 76 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0617 | | Na+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfB (NCBI ptt file) | strong | 33 | 75 |
| | Methanococcus maripaludis JJ | MMJJ_RS05645 | | 4Fe-4S binding protein | sig. | 33 | 81 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02236 | | electron transport complex, RnfABCDGE type, B subunit | strong | 33 | 75 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS15450 | | Fe-S cluster domain-containing protein | insig. | 33 | 75 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1198 | | Iron-sulfur cluster-binding protein | insig. | 35 | 60 |
| | Methanococcus maripaludis S2 | MMP_RS08345 | | 4Fe-4S binding protein | strong | 30 | 76 |
| | Methanococcus maripaludis JJ | MMJJ_RS05645 | | 4Fe-4S binding protein | sig. | 28 | 84 |
| | Methanococcus maripaludis S2 | MMP_RS08720 | | 4Fe-4S binding protein | strong | 28 | 84 |
| | Methanococcus maripaludis JJ | MMJJ_RS07945 | | 4Fe-4S binding protein | strong | 34 | 61 |
| | Methanococcus maripaludis S2 | MMP_RS06405 | | 4Fe-4S binding protein | no data | 34 | 61 |
| | Methanococcus maripaludis S2 | MMP_RS07525 | | 4Fe-4S binding protein | strong | 29 | 80 |
| | Methanococcus maripaludis S2 | MMP_RS08720 | | 4Fe-4S binding protein | strong | 28 | 84 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0963 | | putative ferredoxin-type protein (NCBI ptt file) | sig. | 27 | 74 |
| | Bosea sp. OAE506 | ABIE41_RS23405 | | 4Fe-4S binding protein | insig. | 44 | 30 |
| | Dinoroseobacter shibae DFL-12 | Dshi_0496 | | 4Fe-4S ferredoxin iron-sulfur binding domain protein (RefSeq) | insig. | 41 | 34 |
| | Methanococcus maripaludis JJ | MMJJ_RS06835 | | 4Fe-4S binding protein | strong | 30 | 80 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4713 | | Formate hydrogenlyase complex 3 iron-sulfur protein; Formate hydrogenlyase subunit 6; Ni,Fe-hydrogenase III medium subunit | insig. | 38 | 34 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS08780 | | 4Fe-4S binding protein | strong | 28 | 74 |
| | Methanococcus maripaludis S2 | MMP_RS08345 | | 4Fe-4S binding protein | strong | 33 | 72 |
| | Methanococcus maripaludis S2 | MMP_RS08345 | | 4Fe-4S binding protein | strong | 31 | 73 |
| | Methanococcus maripaludis JJ | MMJJ_RS06025 | | 4Fe-4S binding protein | strong | 31 | 81 |
| | Dickeya dadantii 3937 | DDA3937_RS07440 | | hydrogenase 4 subunit H | insig. | 29 | 49 |
| | Dickeya dianthicola 67-19 | HGI48_RS07315 | | hydrogenase 4 subunit H | insig. | 29 | 49 |
| | Dickeya dianthicola ME23 | DZA65_RS07825 | | hydrogenase 4 subunit H | insig. | 29 | 49 |
| | Escherichia fergusonii Becca | EFB2_01203 | | NAD(P)H-quinone oxidoreductase subunit I, chloroplastic | insig. | 38 | 34 |
| | Klebsiella michiganensis M5al | BWI76_RS22315 | | formate hydrogenlyase complex iron-sulfur subunit | insig. | 36 | 34 |
| | Methanococcus maripaludis JJ | MMJJ_RS00860 | | 4Fe-4S binding protein | insig. | 33 | 81 |
| | Escherichia coli ECOR27 | NOLOHH_12440 | hycF | formate hydrogenlyase subunit HycF | insig. | 38 | 34 |
| | Escherichia coli ECRC62 | BNILDI_10990 | hycF | formate hydrogenlyase subunit HycF | insig. | 38 | 34 |
| | Escherichia coli BL21 | ECD_02570 | | formate hydrogenlyase complex iron-sulfur protein | insig. | 38 | 34 |
| | Escherichia coli ECOR38 | HEPCGN_19785 | hycF | formate hydrogenlyase subunit HycF | insig. | 38 | 34 |
| | Escherichia coli ECRC100 | OKFHMN_20595 | hycF | formate hydrogenlyase subunit HycF | insig. | 38 | 34 |
| | Escherichia coli ECRC101 | MCAODC_11120 | hycF | formate hydrogenlyase subunit HycF | sig. | 38 | 34 |
| | Escherichia coli ECRC102 | NIAGMN_18365 | hycF | formate hydrogenlyase subunit HycF | cofit | 38 | 34 |
| | Escherichia coli ECRC98 | JDDGAC_24260 | hycF | formate hydrogenlyase subunit HycF | insig. | 38 | 34 |
| | Escherichia coli ECRC99 | KEDOAH_07540 | hycF | formate hydrogenlyase subunit HycF | no data | 38 | 34 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01014 | | NAD(P)H-quinone oxidoreductase subunit I, chloroplastic | insig. | 38 | 34 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_2811 | | Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) | insig. | 36 | 34 |
| | Enterobacter sp. TBS_079 | MPMX20_03605 | | NAD(P)H-quinone oxidoreductase subunit I, chloroplastic | insig. | 36 | 34 |
| | Methanococcus maripaludis S2 | MMP_RS08345 | | 4Fe-4S binding protein | strong | 33 | 80 |
| | Methanococcus maripaludis JJ | MMJJ_RS00860 | | 4Fe-4S binding protein | insig. | 30 | 86 |
| | Methanococcus maripaludis JJ | MMJJ_RS05645 | | 4Fe-4S binding protein | sig. | 26 | 88 |
| | Methanococcus maripaludis S2 | MMP_RS04290 | | 4Fe-4S binding protein | sig. | 28 | 81 |
| | Azospirillum brasilense Sp245 | AZOBR_RS23115 | | ferredoxin | insig. | 29 | 78 |
| | Dinoroseobacter shibae DFL-12 | Dshi_3167 | | ferredoxin-type protein NapF (RefSeq) | insig. | 27 | 78 |
| | Azospirillum sp. SherDot2 | MPMX19_03509 | | NAD(P)H-quinone oxidoreductase subunit I, chloroplastic | insig. | 43 | 34 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS09465 | | 4Fe-4S binding protein | insig. | 29 | 74 |
| | Methanococcus maripaludis JJ | MMJJ_RS00860 | | 4Fe-4S binding protein | insig. | 27 | 83 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS07530 | | glycyl-radical enzyme activating protein | insig. | 38 | 36 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2713 | | 4Fe-4S ferredoxin iron-sulfur binding domain protein (RefSeq) | insig. | 27 | 73 |
| | Escherichia coli BW25113 | b2720 | hycF | formate hydrogenlyase complex iron-sulfur protein (NCBI) | insig. | 38 | 34 |
| | Variovorax sp. OAS795 | ABID97_RS07550 | | 4Fe-4S dicluster domain-containing protein | insig. | 29 | 60 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS04220 | | glycyl-radical enzyme activating protein | insig. | 46 | 32 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS15200 | | formate hydrogenlyase subunit HycF | insig. | 36 | 34 |
| | Methanococcus maripaludis JJ | MMJJ_RS06835 | | 4Fe-4S binding protein | strong | 28 | 90 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS12510 | | glycyl-radical enzyme activating protein | strong | 46 | 32 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_02985 | | formate hydrogenlyase complex iron-sulfur subunit | no data | 36 | 34 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS12990 | | 4Fe-4S dicluster domain-containing protein | insig. | 33 | 60 |
| | Marinobacter adhaerens HP15 | HP15_4124 | | protein containing 4Fe-4S ferredoxin, iron-sulfur binding, subgroup domains | strong | 41 | 34 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS16235 | | 4Fe-4S binding protein | cofit | 38 | 32 |
| | Shewanella sp. ANA-3 | Shewana3_3913 | | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (RefSeq) | cofit | 35 | 50 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS04380 | | 4Fe-4S ferredoxin | insig. | 34 | 34 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS12990 | | 4Fe-4S dicluster domain-containing protein | insig. | 34 | 34 |
| | Ralstonia solanacearum UW163 | UW163_RS09290 | | 4Fe-4S ferredoxin | insig. | 34 | 34 |
| | Methanococcus maripaludis S2 | MMP_RS04290 | | 4Fe-4S binding protein | sig. | 32 | 81 |
| | Methanococcus maripaludis S2 | MMP_RS07525 | | 4Fe-4S binding protein | strong | 28 | 90 |
| | Escherichia coli ECOR27 | NOLOHH_11540 | ygfT | formate-dependent uric acid utilization protein YgfT | insig. | 28 | 76 |
| | Escherichia coli ECRC62 | BNILDI_10065 | ygfT | formate-dependent uric acid utilization protein YgfT | insig. | 28 | 76 |
| | Escherichia coli BW25113 | b2887 | ygfT | putative oxidoreductase, Fe-S subunit (VIMSS) | insig. | 28 | 76 |
| | Escherichia coli ECRC100 | OKFHMN_19610 | ygfT | formate-dependent uric acid utilization protein YgfT | insig. | 28 | 76 |
| | Escherichia coli ECRC101 | MCAODC_10135 | ygfT | formate-dependent uric acid utilization protein YgfT | insig. | 28 | 76 |
| | Escherichia coli ECRC102 | NIAGMN_17380 | ygfT | formate-dependent uric acid utilization protein YgfT | insig. | 28 | 76 |