| Orth |  Species |  Gene |  Name |  Description |  Fitness |  %Id |  Cov | 
|   |  Rahnella sp. WP5 |  EX31_RS02520 |   |  sigma-54-dependent Fis family transcriptional regulator |  strong |  100 |  100 | 
| o |  Dickeya dianthicola 67-19 |  HGI48_RS00425 |   |  two-component system response regulator VfmH |  cofit |  65 |  100 | 
| o |  Dickeya dianthicola ME23 |  DZA65_RS00425 |   |  sigma-54-dependent Fis family transcriptional regulator |  cofit |  65 |  100 | 
| o |  Dickeya dadantii 3937 |  DDA3937_RS20820 |   |  two-component system response regulator VfmH |  strong |  65 |  100 | 
| o |  Dyella japonica UNC79MFTsu3.2 |  ABZR86_RS04010 |   |  sigma-54 dependent transcriptional regulator |  insig. |  48 |  97 | 
| o |  Rhodanobacter denitrificans MT42 |  LRK55_RS11840 |   |  sigma-54 dependent transcriptional regulator |  insig. |  47 |  97 | 
| o |  Rhodanobacter denitrificans FW104-10B01 |  LRK54_RS12105 |   |  sigma-54 dependent transcriptional regulator |  insig. |  47 |  97 | 
| o |  Echinicola vietnamensis KMM 6221, DSM 17526 |  Echvi_2422 |   |  Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains |  strong |  43 |  98 | 
| o |  Pontibacter actiniarum KMM 6156, DSM 19842 |  CA264_07535 |   |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  44 |  98 | 
| o |  Phocaeicola vulgatus CL09T03C04 |  HMPREF1058_RS03345 |   |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  42 |  99 | 
| o |  Phocaeicola dorei CL03T12C01 |  ABI39_RS17680 |   |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  41 |  99 | 
| o |  Parabacteroides merdae CL09T00C40 |  HMPREF1078_RS08600 |   |  sigma-54 dependent transcriptional regulator |  insig. |  43 |  99 | 
|   |  Phocaeicola vulgatus CL09T03C04 |  HMPREF1058_RS01145 |   |  sigma-54-dependent Fis family transcriptional regulator |  strong |  41 |  99 | 
| o |  Bacteroides ovatus ATCC 8483 |  BACOVA_04200 |   |  Sigma-54 interaction domain protein |  insig. |  41 |  99 | 
| o |  Bacteroides thetaiotaomicron VPI-5482 |  BT1529 |   |  two-component system response regulator (NCBI ptt file) |  strong |  44 |  98 | 
|   |  Phocaeicola dorei CL03T12C01 |  ABI39_RS16590 |   |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  41 |  99 | 
|   |  Bacteroides ovatus ATCC 8483 |  BACOVA_04264 |   |  Sigma-54 interaction domain protein |  insig. |  44 |  98 | 
| o |  Bacteroides stercoris CC31F |  HMPREF1181_RS04840 |   |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  44 |  98 | 
|   |  Parabacteroides merdae CL09T00C40 |  HMPREF1078_RS12140 |   |  sigma-54 dependent transcriptional regulator |  insig. |  43 |  98 | 
|   |  Phocaeicola dorei CL03T12C01 |  ABI39_RS11790 |   |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  43 |  98 | 
|   |  Phocaeicola dorei CL03T12C01 |  ABI39_RS17605 |   |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  41 |  99 | 
|   |  Phocaeicola vulgatus CL09T03C04 |  HMPREF1058_RS15800 |   |  sigma-54-dependent Fis family transcriptional regulator |  strong |  43 |  98 | 
|   |  Bacteroides ovatus ATCC 8483 |  BACOVA_02581 |   |  Sigma-54 interaction domain protein |  insig. |  41 |  99 | 
|   |  Phocaeicola vulgatus CL09T03C04 |  HMPREF1058_RS03545 |   |  sigma-54-dependent Fis family transcriptional regulator |  strong |  41 |  99 | 
|   |  Parabacteroides merdae CL09T00C40 |  HMPREF1078_RS05570 |   |  sigma-54 dependent transcriptional regulator |  insig. |  42 |  98 | 
|   |  Bacteroides thetaiotaomicron VPI-5482 |  BT0856 |   |  two-component system response regulator (NCBI ptt file) |  sig. |  41 |  99 | 
| o |  Shewanella sp. ANA-3 |  Shewana3_3257 |   |  two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) |  insig. |  41 |  98 | 
|   |  Pontibacter actiniarum KMM 6156, DSM 19842 |  CA264_02275 |   |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  40 |  98 | 
|   |  Bacteroides thetaiotaomicron VPI-5482 |  BT1469 |   |  two-component system response regulator (NCBI ptt file) |  sig. |  40 |  99 | 
|   |  Pontibacter actiniarum KMM 6156, DSM 19842 |  CA264_14055 |   |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  40 |  98 | 
|   |  Bacteroides stercoris CC31F |  HMPREF1181_RS16190 |   |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  42 |  99 | 
|   |  Parabacteroides merdae CL09T00C40 |  HMPREF1078_RS14460 |   |  sigma-54 dependent transcriptional regulator |  insig. |  42 |  98 | 
|   |  Bacteroides thetaiotaomicron VPI-5482 |  BT0690 |   |  two-component system response regulator (NCBI ptt file) |  insig. |  40 |  99 | 
| o |  Shewanella oneidensis MR-1 |  SO3689 |   |  sigma-54 dependent nitrogen response regulator (NCBI ptt file) |  sig. |  40 |  98 | 
| o |  Pedobacter sp. GW460-11-11-14-LB5 |  CA265_RS04165 |   |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  43 |  90 | 
|   |  Bacteroides ovatus ATCC 8483 |  BACOVA_02393 |   |  Sigma-54 interaction domain protein |  insig. |  38 |  99 | 
| o |  Shewanella amazonensis SB2B |  Sama_2861 |   |  response regulator receiver protein (RefSeq) |  insig. |  38 |  99 | 
| o |  Shewanella loihica PV-4 |  Shew_0726 |   |  two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) |  insig. |  37 |  98 | 
| o |  Mucilaginibacter yixingensis YX-36 DSM 26809 |  ABZR88_RS13070 |   |  sigma-54 dependent transcriptional regulator |  cofit |  39 |  96 | 
|   |  Klebsiella michiganensis M5al |  BWI76_RS01605 |   |  transcriptional regulatory protein ZraR |  insig. |  41 |  99 | 
|   |  Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 |  GFF4188 |   |  Response regulator of zinc sigma-54-dependent two-component system |  insig. |  41 |  98 | 
| o |  Rhodanobacter sp000427505 FW510-R12 |  LRK53_RS05540 |   |  sigma-54 dependent transcriptional regulator |  insig. |  40 |  99 | 
|   |  Klebsiella pneumoniae MKP103 |  KDGMDA_10090 |   |  sigma-54-dependent response regulator transcription factor ZraR |  insig. |  39 |  99 | 
| o |  Rhodanobacter sp. FW510-T8 |  OKGIIK_11280 |  atoC |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  40 |  99 | 
|   |  Dyella japonica UNC79MFTsu3.2 |  ABZR86_RS10560 |   |  sigma-54 dependent transcriptional regulator |  insig. |  39 |  99 | 
| o |  Sphingobium sp. HT1-2 |  GFF3845 |   |  Two-component transcriptional response regulator, LuxR family |  cofit |  41 |  88 | 
|   |  Desulfovibrio vulgaris Hildenborough JW710 |  DVU3220 |  atoC |  sigma-54 dependent transcriptional regulator/response regulator (TIGR) |  no data |  40 |  100 | 
|   |  Desulfovibrio vulgaris Miyazaki F |  DvMF_0823 |   |  two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) |  insig. |  40 |  98 | 
|   |  Escherichia coli BL21 |  ECD_03881 |   |  fused DNA-binding response regulator in two-component regulatory system with ZraS: response regulator/sigma54 interaction protein |  insig. |  40 |  97 | 
|   |  Escherichia coli ECOR27 |  NOLOHH_05465 |  zraR |  sigma-54-dependent response regulator transcription factor ZraR |  insig. |  40 |  97 | 
| o |  Pseudomonas fluorescens FW300-N1B4 |  Pf1N1B4_1885 |   |  alginate biosynthesis transcriptional regulatory protein AlgB |  sig. |  40 |  97 | 
|   |  Rhodanobacter denitrificans MT42 |  LRK55_RS04170 |   |  sigma-54 dependent transcriptional regulator |  cofit |  39 |  99 | 
|   |  Rhodanobacter denitrificans FW104-10B01 |  LRK54_RS04395 |   |  sigma-54 dependent transcriptional regulator |  cofit |  39 |  99 | 
|   |  Escherichia coli ECRC62 |  BNILDI_06055 |  zraR |  sigma-54-dependent response regulator transcription factor ZraR |  insig. |  40 |  97 | 
|   |  Escherichia coli HS(pFamp)R (ATCC 700891) |  OHPLBJKB_04045 |   |  Transcriptional regulatory protein ZraR |  insig. |  40 |  97 | 
|   |  Escherichia coli BW25113 |  b4004 |  zraR |  fused DNA-binding response regulator in two-component regulatory system with ZraS: response regulator/sigma54 interaction protein (NCBI) |  insig. |  40 |  97 | 
|   |  Escherichia coli Nissle 1917 |  ECOLIN_RS23090 |   |  sigma-54-dependent response regulator transcription factor ZraR |  insig. |  40 |  97 | 
|   |  Escherichia fergusonii Becca |  EFB2_04606 |   |  Transcriptional regulatory protein ZraR |  insig. |  40 |  97 | 
| o |  Pseudomonas fluorescens FW300-N2E3 |  AO353_10980 |   |  chemotaxis protein CheY |  insig. |  39 |  97 | 
| o |  Pseudomonas sp. BP01 |  JOY50_RS21060 |  algB |  sigma-54-dependent response regulator transcription factor AlgB |  insig. |  39 |  98 | 
|   |  Escherichia coli ECOR38 |  HEPCGN_11960 |  zraR |  sigma-54-dependent response regulator transcription factor ZraR |  insig. |  40 |  97 | 
| o |  Pseudomonas sp. DMC3 |  GFF621 |   |  Alginate biosynthesis transcriptional regulatory protein AlgB |  insig. |  39 |  98 | 
|   |  Desulfovibrio vulgaris Miyazaki F |  DvMF_1461 |   |  two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) |  no data |  38 |  98 | 
|   |  Escherichia coli ECRC101 |  MCAODC_03820 |  zraR |  sigma-54-dependent response regulator transcription factor ZraR |  insig. |  40 |  97 | 
|   |  Escherichia coli ECRC102 |  NIAGMN_11070 |  zraR |  sigma-54-dependent response regulator transcription factor ZraR |  insig. |  40 |  97 | 
|   |  Escherichia coli ECRC99 |  KEDOAH_14840 |  zraR |  sigma-54-dependent response regulator transcription factor ZraR |  no data |  40 |  97 | 
|   |  Desulfovibrio vulgaris Miyazaki F |  DvMF_2200 |   |  two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) |  no data |  40 |  100 | 
| o |  Pseudomonas putida KT2440 |  PP_0133 |   |  Alginate biosynthesis transcriptional regulatory protein AlgB |  sig. |  39 |  98 | 
| o |  Pseudomonas fluorescens FW300-N2C3 |  AO356_11415 |   |  chemotaxis protein CheY |  strong |  39 |  97 | 
| o |  Pseudomonas sp. RS175 |  PFR28_04634 |   |  Alginate biosynthesis transcriptional regulatory protein AlgB |  strong |  39 |  97 | 
| o |  Pseudomonas sp. SVBP6 |  COO64_RS02525 |  algB |  sigma-54-dependent response regulator transcription factor AlgB |  insig. |  39 |  97 | 
| o |  Pseudomonas fluorescens GW456-L13 |  PfGW456L13_584 |   |  alginate biosynthesis transcriptional regulatory protein AlgB |  sig. |  39 |  97 | 
| o |  Pseudomonas fluorescens FW300-N2E2 |  Pf6N2E2_4152 |   |  alginate biosynthesis transcriptional regulatory protein AlgB |  strong |  39 |  97 | 
| o |  Ralstonia solanacearum IBSBF1503 |  RALBFv3_RS10795 |   |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  39 |  99 | 
| o |  Ralstonia solanacearum GMI1000 |  RS_RS01635 |   |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  39 |  99 | 
| o |  Ralstonia solanacearum UW163 |  UW163_RS02785 |   |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  39 |  99 | 
|   |  Paraburkholderia sabiae LMG 24235 |  QEN71_RS37765 |   |  sigma-54 dependent transcriptional regulator |  insig. |  37 |  100 | 
|   |  Escherichia coli ECRC100 |  OKFHMN_13320 |  zraR |  sigma-54-dependent response regulator transcription factor ZraR |  cofit |  40 |  97 | 
|   |  Escherichia coli ECRC98 |  JDDGAC_16945 |  zraR |  sigma-54-dependent response regulator transcription factor ZraR |  insig. |  40 |  97 | 
| o |  Xanthomonas campestris pv. campestris strain 8004 |  Xcc-8004.4560.1 |   |  Histidine kinase/response regulator hybrid protein |  insig. |  39 |  99 | 
| o |  Pseudomonas simiae WCS417 |  PS417_00450 |   |  chemotaxis protein CheY |  strong |  39 |  97 | 
| o |  Lysobacter sp. OAE881 |  ABIE51_RS18345 |   |  sigma-54 dependent transcriptional regulator |  insig. |  39 |  99 | 
| o |  Pseudomonas lactucae CFBP13502 |  GEMAOFIL_00293 |   |  Alginate biosynthesis transcriptional regulatory protein AlgB |  cofit |  39 |  97 | 
| o |  Ralstonia solanacearum PSI07 |  RPSI07_RS22520 |   |  sigma-54-dependent Fis family transcriptional regulator |  insig. |  39 |  99 | 
|   |  Pseudomonas lactucae CFBP13502 |  GEMAOFIL_01292 |   |  Regulatory protein AtoC |  cofit |  39 |  98 | 
|   |  Pseudomonas simiae WCS417 |  PS417_05525 |   |  Fis family transcriptional regulator |  strong |  39 |  98 | 
| o |  Pseudomonas aeruginosa PA14 |  IKLFDK_26000 |   |  sigma-54-dependent response regulator transcription factor AlgB |  insig. |  38 |  98 | 
|   |  Desulfovibrio vulgaris Hildenborough JW710 |  DVU0110 |  ntrC |  sigma-54 dependent transcriptional regulator/response regulator (TIGR) |  cofit |  37 |  98 | 
| o |  Pseudomonas fluorescens SBW25 |  PFLU_RS00440 |   |  sigma-54-dependent Fis family transcriptional regulator |  cofit |  39 |  97 | 
| o |  Pseudomonas fluorescens SBW25-INTG |  PFLU_RS00440 |   |  sigma-54-dependent Fis family transcriptional regulator |  strong |  39 |  97 | 
| o |  Cupriavidus basilensis FW507-4G11 |  RR42_RS03980 |   |  Fis family transcriptional regulator |  strong |  37 |  98 | 
|   |  Cupriavidus basilensis FW507-4G11 |  RR42_RS01705 |   |  Fis family transcriptional regulator |  insig. |  38 |  99 | 
|   |  Variovorax sp. SCN45 |  GFF7323 |   |  Transcriptional response regulatory protein GlrR |  insig. |  40 |  98 | 
|   |  Pseudomonas fluorescens SBW25 |  PFLU_RS05610 |   |  sigma-54-dependent Fis family transcriptional regulator |  strong |  39 |  98 | 
|   |  Pseudomonas fluorescens SBW25-INTG |  PFLU_RS05610 |   |  sigma-54-dependent Fis family transcriptional regulator |  strong |  39 |  98 | 
| o |  Pseudomonas syringae pv. syringae B728a |  Psyr_0263 |   |  Two-component response regulator AlgB |  sig. |  38 |  97 | 
| o |  Pseudomonas syringae pv. syringae B728a ΔmexB |  Psyr_0263 |   |  Two-component response regulator AlgB |  sig. |  38 |  97 | 
|   |  Paraburkholderia graminis OAS925 |  ABIE53_001852 |   |  two-component system C4-dicarboxylate transport response regulator DctD |  strong |  37 |  100 | 
| o |  Burkholderia phytofirmans PsJN |  BPHYT_RS02520 |   |  Fis family transcriptional regulator |  strong |  36 |  100 | 
|   |  Pseudomonas sp. DMC3 |  GFF5115 |   |  C4-dicarboxylate transport transcriptional regulatory protein DctD |  insig. |  36 |  100 |