Conservation of cofitness between PP_1598 and PP_4892 in Pseudomonas putida KT2440

66 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_1598 regulatory intramembrane protein RIP zinc protease 1.0 PP_4892 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex 0.39 3
Pseudomonas fluorescens SBW25 0.83 PFLU_RS06310 sigma E protease regulator RseP 0.75 PFLU_RS02580 FtsH protease activity modulator HflK 0.64 56
Pseudomonas fluorescens SBW25-INTG 0.83 PFLU_RS06310 sigma E protease regulator RseP 0.75 PFLU_RS02580 FtsH protease activity modulator HflK 0.48 22
Pseudomonas simiae WCS417 0.83 PS417_06245 zinc metallopeptidase RseP 0.74 PS417_02500 membrane protein — —
Pseudomonas fluorescens FW300-N2E3 0.82 AO353_16495 zinc metallopeptidase RseP 0.77 AO353_13155 hypothetical protein low > 101
Pseudomonas sp. RS175 0.82 PFR28_00403 Regulator of sigma-E protease RseP 0.76 PFR28_05123 Modulator of FtsH protease HflK low > 88
Pseudomonas fluorescens FW300-N2C3 0.82 AO356_06005 zinc metallopeptidase RseP 0.74 AO356_08645 hypothetical protein low > 104
Pseudomonas fluorescens GW456-L13 0.81 PfGW456L13_4701 Membrane-associated zinc metalloprotease 0.74 PfGW456L13_152 HflK protein low > 87
Pseudomonas fluorescens FW300-N2E2 0.81 Pf6N2E2_3062 Membrane-associated zinc metalloprotease 0.73 Pf6N2E2_3612 HflK protein low > 103
Pseudomonas syringae pv. syringae B728a 0.81 Psyr_1350 site-2 protease, Metallo peptidase, MEROPS family M50B 0.72 Psyr_0574 protease FtsH subunit HflK low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.81 Psyr_1350 site-2 protease, Metallo peptidase, MEROPS family M50B 0.72 Psyr_0574 protease FtsH subunit HflK low > 86
Pseudomonas fluorescens FW300-N1B4 0.80 Pf1N1B4_3091 Membrane-associated zinc metalloprotease 0.75 Pf1N1B4_1410 HflK protein — —
Pseudomonas stutzeri RCH2 0.80 Psest_2835 RIP metalloprotease RseP 0.66 Psest_0685 HflK protein — —
Pseudomonas sp. S08-1 0.78 OH686_06450 RIP metalloprotease RseP 0.64 OH686_09460 HflK protein — —
Marinobacter adhaerens HP15 0.51 HP15_1173 membrane-associated zinc metalloprotease 0.43 HP15_2497 HflK low > 73
Alteromonas macleodii MIT1002 0.44 MIT1002_01011 Regulator of sigma E protease 0.34 MIT1002_03786 Modulator of FtsH protease HflK low > 70
Enterobacter asburiae PDN3 0.43 EX28DRAFT_3764 RIP metalloprotease RseP 0.33 EX28DRAFT_3371 HflK protein — —
Escherichia coli ECRC62 0.43 BNILDI_09150 rseP sigma E protease regulator RseP 0.33 BNILDI_06980 hflK FtsH protease activity modulator HflK — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.43 OHPLBJKB_03487 Regulator of sigma-E protease RseP 0.33 OHPLBJKB_03868 Modulator of FtsH protease HflK — —
Pantoea sp. MT58 0.43 IAI47_15495 sigma E protease regulator RseP 0.30 IAI47_02600 FtsH protease activity modulator HflK — —
Escherichia coli ECRC102 0.43 NIAGMN_08025 rseP sigma E protease regulator RseP 0.33 NIAGMN_10095 hflK FtsH protease activity modulator HflK — —
Escherichia coli ECRC101 0.43 MCAODC_00690 rseP sigma E protease regulator RseP 0.33 MCAODC_02760 hflK FtsH protease activity modulator HflK — —
Enterobacter sp. TBS_079 0.43 MPMX20_00860 Regulator of sigma-E protease RseP 0.31 MPMX20_00455 Modulator of FtsH protease HflK — —
Escherichia coli BL21 0.43 ECD_00174 inner membrane zinc RIP metalloprotease; RpoE activator, by degrading RseA; cleaved signal peptide endoprotease 0.33 ECD_04041 modulator for HflB protease specific for phage lambda cII repressor — —
Escherichia coli ECRC99 0.43 KEDOAH_17980 rseP sigma E protease regulator RseP 0.33 KEDOAH_15910 hflK FtsH protease activity modulator HflK — —
Escherichia coli Nissle 1917 0.43 ECOLIN_RS00960 sigma E protease regulator RseP 0.33 ECOLIN_RS24240 FtsH protease activity modulator HflK — —
Escherichia coli ECRC101 0.43 OKFHMN_10175 rseP sigma E protease regulator RseP 0.33 OKFHMN_12245 hflK FtsH protease activity modulator HflK — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.43 GFF46 Intramembrane protease RasP/YluC, implicated in cell division based on FtsL cleavage 0.32 GFF827 HflK protein — —
Escherichia coli ECOR27 0.43 NOLOHH_02520 rseP sigma E protease regulator RseP 0.33 NOLOHH_04510 hflK FtsH protease activity modulator HflK — —
Escherichia coli ECRC98 0.43 JDDGAC_13770 rseP sigma E protease regulator RseP 0.33 JDDGAC_15885 hflK FtsH protease activity modulator HflK — —
Escherichia coli ECOR38 0.43 HEPCGN_08130 rseP sigma E protease regulator RseP 0.33 HEPCGN_10475 hflK FtsH protease activity modulator HflK — —
Escherichia fergusonii Becca 0.43 EFB2_03868 Regulator of sigma-E protease RseP 0.33 EFB2_04361 Modulator of FtsH protease HflK — —
Escherichia coli BW25113 0.43 b0176 yaeL zinc metallopeptidase (NCBI) 0.33 b4174 hflK modulator for HflB protease specific for phage lambda cII repressor (NCBI) — —
Serratia liquefaciens MT49 0.42 IAI46_20225 sigma E protease regulator RseP 0.31 IAI46_01635 FtsH protease activity modulator HflK — —
Erwinia tracheiphila SCR3 0.42 LU632_RS19930 rseP sigma E protease regulator RseP 0.31 LU632_RS02065 hflK FtsH protease activity modulator HflK low > 74
Shewanella oneidensis MR-1 0.42 SO1636 membrane-associated zinc metalloprotease, putative (NCBI ptt file) 0.33 SO0605 hflK hflK protein (NCBI ptt file) — —
Shewanella sp. ANA-3 0.42 Shewana3_2808 peptidase RseP (RefSeq) 0.34 Shewana3_0599 HflK protein (RefSeq) — —
Pectobacterium carotovorum WPP14 0.41 HER17_RS16300 sigma E protease regulator RseP 0.31 HER17_RS02595 FtsH protease activity modulator HflK low > 75
Shewanella loihica PV-4 0.41 Shew_2628 putative membrane-associated zinc metalloprotease (RefSeq) 0.33 Shew_0568 HflK protein (RefSeq) — —
Klebsiella michiganensis M5al 0.41 BWI76_RS05250 zinc metallopeptidase RseP 0.32 BWI76_RS02545 protease modulator HflK — —
Vibrio cholerae E7946 ATCC 55056 0.40 CSW01_11475 zinc metalloprotease 0.33 CSW01_01845 protease modulator HflK — —
Rahnella sp. WP5 0.40 EX31_RS13000 sigma E protease regulator RseP 0.32 EX31_RS08810 FtsH protease activity modulator HflK — —
Shewanella amazonensis SB2B 0.40 Sama_1146 membrane-associated zinc metalloprotease, putative (RefSeq) 0.35 Sama_3023 hflK protein (RefSeq) low > 62
Dickeya dianthicola ME23 0.40 DZA65_RS05490 sigma E protease regulator RseP 0.34 DZA65_RS19670 FtsH protease activity modulator HflK low > 75
Dickeya dadantii 3937 0.40 DDA3937_RS05150 sigma E protease regulator RseP 0.33 DDA3937_RS18600 FtsH protease activity modulator HflK low > 74
Dickeya dianthicola 67-19 0.40 HGI48_RS05150 sigma E protease regulator RseP 0.33 HGI48_RS18535 FtsH protease activity modulator HflK low > 71
Rhodanobacter sp. FW510-T8 0.37 OKGIIK_10175 rseP RIP metalloprotease RseP 0.29 OKGIIK_06640 hflK FtsH protease activity modulator HflK 0.75 29
Lysobacter sp. OAE881 0.37 ABIE51_RS06905 RIP metalloprotease RseP 0.25 ABIE51_RS06550 FtsH protease activity modulator HflK low > 62
Castellaniella sp019104865 MT123 0.36 ABCV34_RS04075 RIP metalloprotease RseP 0.30 ABCV34_RS02660 FtsH protease activity modulator HflK — —
Dechlorosoma suillum PS 0.36 Dsui_2687 RIP metalloprotease RseP 0.35 Dsui_3135 HflK protein — —
Rhodanobacter denitrificans FW104-10B01 0.36 LRK54_RS03290 RIP metalloprotease RseP 0.28 LRK54_RS00620 FtsH protease activity modulator HflK 0.82 31
Rhodanobacter denitrificans MT42 0.36 LRK55_RS03040 RIP metalloprotease RseP 0.29 LRK55_RS00390 FtsH protease activity modulator HflK — —
Dyella japonica UNC79MFTsu3.2 0.35 ABZR86_RS21620 RIP metalloprotease RseP 0.28 ABZR86_RS08355 FtsH protease activity modulator HflK — —
Variovorax sp. SCN45 0.33 GFF386 Membrane-associated zinc metalloprotease 0.31 GFF1002 HflK protein low > 127
Kangiella aquimarina DSM 16071 0.33 B158DRAFT_1087 site-2 protease. Metallo peptidase. MEROPS family M50B 0.30 B158DRAFT_1954 protease FtsH subunit HflK low > 40
Paraburkholderia bryophila 376MFSha3.1 0.32 H281DRAFT_00617 site-2 protease. Metallo peptidase. MEROPS family M50B 0.29 H281DRAFT_00523 protease FtsH subunit HflK — —
Burkholderia phytofirmans PsJN 0.32 BPHYT_RS12105 zinc metalloprotease 0.29 BPHYT_RS12545 membrane protein — —
Variovorax sp. OAS795 0.32 ABID97_RS17135 RIP metalloprotease RseP 0.31 ABID97_RS14260 FtsH protease activity modulator HflK low > 91
Paraburkholderia sabiae LMG 24235 0.32 QEN71_RS06455 RIP metalloprotease RseP 0.32 QEN71_RS06010 FtsH protease activity modulator HflK low > 153
Paraburkholderia graminis OAS925 0.32 ABIE53_002496 regulator of sigma E protease 0.30 ABIE53_002735 membrane protease subunit HflK low > 113
Ralstonia solanacearum IBSBF1503 0.30 RALBFv3_RS00410 RIP metalloprotease RseP 0.32 RALBFv3_RS15310 FtsH protease activity modulator HflK low > 76
Ralstonia solanacearum UW163 0.30 UW163_RS13740 RIP metalloprotease RseP 0.32 UW163_RS12775 FtsH protease activity modulator HflK — —
Ralstonia solanacearum GMI1000 0.30 RS_RS07080 RIP metalloprotease RseP 0.30 RS_RS06120 FtsH protease activity modulator HflK low > 80
Ralstonia sp. UNC404CL21Col 0.29 ABZR87_RS11860 RIP metalloprotease RseP 0.31 ABZR87_RS10950 FtsH protease activity modulator HflK 0.36 30
Ralstonia solanacearum PSI07 0.29 RPSI07_RS17065 RIP metalloprotease RseP 0.32 RPSI07_RS18065 FtsH protease activity modulator HflK low > 81
Acidovorax sp. GW101-3H11 0.28 Ac3H11_425 Membrane-associated zinc metalloprotease 0.31 Ac3H11_1801 HflK protein — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.25 GFF4908 Membrane-associated zinc metalloprotease 0.33 GFF4856 HflK protein 0.75 9

Not shown: 16 genomes with orthologs for PP_1598 only; 7 genomes with orthologs for PP_4892 only