Conservation of cofitness between PP_2214 and PP_2334 in Pseudomonas putida KT2440

49 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_2214 3-hydroxyacyl-CoA dehydrogenase type-2 1.0 PP_2334 2-methylisocitrate lyase 0.28 16
Pseudomonas fluorescens SBW25 0.80 PFLU_RS14760 SDR family NAD(P)-dependent oxidoreductase 0.91 PFLU_RS22690 methylisocitrate lyase low > 109
Pseudomonas fluorescens SBW25-INTG 0.80 PFLU_RS14760 SDR family NAD(P)-dependent oxidoreductase 0.91 PFLU_RS22690 methylisocitrate lyase 0.36 12
Pseudomonas sp. RS175 0.76 PFR28_01881 putative oxidoreductase 0.92 PFR28_02928 2-methylisocitrate lyase 0.51 7
Pseudomonas simiae WCS417 0.75 PS417_13860 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 0.91 PS417_21080 2-methylisocitrate lyase — —
Pseudomonas fluorescens GW456-L13 0.74 PfGW456L13_2981 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) 0.92 PfGW456L13_4118 Methylisocitrate lyase (EC 4.1.3.30) low > 87
Pseudomonas fluorescens FW300-N2E2 0.74 Pf6N2E2_1144 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) 0.91 Pf6N2E2_6061 Methylisocitrate lyase (EC 4.1.3.30) (from data) — —
Pseudomonas fluorescens FW300-N2E3 0.74 AO353_25690 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 0.92 AO353_00900 2-methylisocitrate lyase — —
Pseudomonas fluorescens FW300-N2C3 0.73 AO356_26345 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 0.92 AO356_20865 2-methylisocitrate lyase 0.72 6
Pseudomonas fluorescens FW300-N1B4 0.72 Pf1N1B4_4785 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) 0.92 Pf1N1B4_3819 Methylisocitrate lyase (EC 4.1.3.30) — —
Pseudomonas stutzeri RCH2 0.68 Psest_2447 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) 0.94 Psest_2321 methylisocitrate lyase low > 67
Pseudomonas sp. S08-1 0.67 OH686_00865 3-hydroxyacyl-CoA dehydrogenase or 17hydroxysteroid dehydrogenase type 10 (HSD10)-like 0.74 OH686_01690 methylisocitrate lyase low > 80
Rhodospirillum rubrum S1H 0.66 Rru_A1507 short-chain dehydrogenase/reductase SDR (NCBI) 0.39 Rru_A2320 Ankyrin (NCBI) low > 58
Paraburkholderia bryophila 376MFSha3.1 0.65 H281DRAFT_06131 NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family 0.31 H281DRAFT_02892 carboxyvinyl-carboxyphosphonate phosphorylmutase low > 103
Rhodopseudomonas palustris CGA009 0.65 TX73_011910 3-hydroxyacyl-CoA dehydrogenase 0.36 TX73_012370 methylisocitrate lyase low > 86
Paraburkholderia graminis OAS925 0.64 ABIE53_005415 NAD(P)-dependent dehydrogenase (short-subunit alcohol dehydrogenase family) 0.32 ABIE53_005902 2-methylisocitrate lyase-like PEP mutase family enzyme low > 113
Ralstonia sp. UNC404CL21Col 0.62 ABZR87_RS00745 3-hydroxyacyl-CoA dehydrogenase 0.82 ABZR87_RS14590 methylisocitrate lyase low > 80
Burkholderia phytofirmans PsJN 0.61 BPHYT_RS15890 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 0.32 BPHYT_RS26855 carboxyvinyl-carboxyphosphonate phosphorylmutase low > 109
Herbaspirillum seropedicae SmR1 0.61 HSERO_RS04630 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 0.84 HSERO_RS15660 2-methylisocitrate lyase — —
Ralstonia solanacearum UW163 0.61 UW163_RS08530 3-hydroxyacyl-CoA dehydrogenase 0.82 UW163_RS11055 methylisocitrate lyase — —
Ralstonia solanacearum IBSBF1503 0.61 RALBFv3_RS05095 3-hydroxyacyl-CoA dehydrogenase 0.82 RALBFv3_RS02670 methylisocitrate lyase low > 76
Ralstonia solanacearum GMI1000 0.61 RS_RS12705 3-hydroxyacyl-CoA dehydrogenase 0.82 RS_RS10050 methylisocitrate lyase low > 80
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS02810 3-hydroxyacyl-CoA dehydrogenase 0.79 QEN71_RS17555 methylisocitrate lyase low > 153
Acidovorax sp. GW101-3H11 0.59 Ac3H11_2606 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) @ 17hydroxysteroid dehydrogenase type 10 (HSD10)-like 0.32 Ac3H11_2326 Methylisocitrate lyase (EC 4.1.3.30) low > 79
Hydrogenophaga sp. GW460-11-11-14-LB1 0.59 GFF3825 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) @ 17hydroxysteroid dehydrogenase type 10 (HSD10)-like 0.33 GFF3032 Methylisocitrate lyase (EC 4.1.3.30) — —
Cupriavidus basilensis FW507-4G11 0.59 RR42_RS03440 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 0.82 RR42_RS11260 Methylisocitrate lyase (EC 4.1.3.30) (from data) low > 128
Ralstonia solanacearum PSI07 0.58 RPSI07_RS12200 3-hydroxyacyl-CoA dehydrogenase 0.82 RPSI07_RS14645 methylisocitrate lyase low > 81
Variovorax sp. OAS795 0.58 ABID97_RS10560 3-hydroxyacyl-CoA dehydrogenase 0.33 ABID97_RS19370 isocitrate lyase/PEP mutase family protein low > 91
Azospirillum sp. SherDot2 0.56 MPMX19_02389 putative oxidoreductase 0.32 MPMX19_04657 2,3-dimethylmalate lyase low > 112
Dyella japonica UNC79MFTsu3.2 0.55 ABZR86_RS08630 SDR family NAD(P)-dependent oxidoreductase 0.73 ABZR86_RS08480 methylisocitrate lyase low > 74
Rhodanobacter sp. FW510-T8 0.55 OKGIIK_09370 fabG 3-hydroxyacyl-CoA dehydrogenase 0.66 OKGIIK_06565 prpB methylisocitrate lyase low > 52
Azospirillum brasilense Sp245 0.54 AZOBR_RS26110 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 0.29 AZOBR_RS24315 carboxyvinyl-carboxyphosphonate phosphorylmutase — —
Acinetobacter radioresistens SK82 0.54 MPMX26_01177 putative oxidoreductase 0.63 MPMX26_01289 2-methylisocitrate lyase — —
Rhodanobacter denitrificans MT42 0.54 LRK55_RS02080 SDR family oxidoreductase 0.66 LRK55_RS00470 methylisocitrate lyase low > 63
Rhodanobacter denitrificans FW104-10B01 0.54 LRK54_RS02325 SDR family oxidoreductase 0.66 LRK54_RS00695 methylisocitrate lyase 0.78 15
Castellaniella sp019104865 MT123 0.54 ABCV34_RS05365 3-hydroxyacyl-CoA dehydrogenase 0.74 ABCV34_RS01670 methylisocitrate lyase low > 48
Marinobacter adhaerens HP15 0.53 HP15_1007 3-hydroxyacyl-CoA dehydrogenase type II 0.67 HP15_1932 methylisocitrate lyase 2 — —
Lysobacter sp. OAE881 0.53 ABIE51_RS13215 SDR family NAD(P)-dependent oxidoreductase 0.64 ABIE51_RS06015 methylisocitrate lyase — —
Alteromonas macleodii MIT1002 0.51 MIT1002_01862 Levodione reductase 0.64 MIT1002_03129 Methylisocitrate lyase low > 70
Dinoroseobacter shibae DFL-12 0.50 Dshi_1700 short-chain dehydrogenase/reductase SDR (RefSeq) 0.30 Dshi_0689 isocitrate lyase family protein (RefSeq) low > 64
Xanthomonas campestris pv. campestris strain 8004 0.49 Xcc-8004.2924.1 Short-chain dehydrogenase/reductase SDR 0.71 Xcc-8004.3981.1 Methylisocitrate lyase (EC 4.1.3.30) low > 74
Variovorax sp. SCN45 0.49 GFF2281 Short-chain dehydrogenase/reductase SDR 0.33 GFF268 Carboxyvinyl-carboxyphosphonate phosphorylmutase (EC 2.7.8.23) 0.52 91
Kangiella aquimarina DSM 16071 0.48 B158DRAFT_1000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) 0.66 B158DRAFT_1343 methylisocitrate lyase 0.44 39
Bosea sp. OAE506 0.46 ABIE41_RS04860 SDR family NAD(P)-dependent oxidoreductase 0.31 ABIE41_RS16605 isocitrate lyase/PEP mutase family protein low > 77
Pseudomonas syringae pv. syringae B728a ΔmexB 0.29 Psyr_4075 Short-chain dehydrogenase/reductase SDR 0.88 Psyr_2085 methylisocitrate lyase low > 86
Pseudomonas syringae pv. syringae B728a 0.29 Psyr_4075 Short-chain dehydrogenase/reductase SDR 0.88 Psyr_2085 methylisocitrate lyase low > 86
Shewanella loihica PV-4 0.29 Shew_1673 fabG 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) 0.66 Shew_1820 prpB 2-methylisocitrate lyase (RefSeq) low > 60
Shewanella amazonensis SB2B 0.29 Sama_1381 fabG 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) 0.62 Sama_3294 prpB 2-methylisocitrate lyase (RefSeq) low > 62
Shewanella sp. ANA-3 0.28 Shewana3_2765 fabG 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) 0.61 Shewana3_3825 prpB 2-methylisocitrate lyase (RefSeq) — —
Shewanella oneidensis MR-1 0.27 SO1683 3-hydroxy-2-methylbutyryl-CoA dehydrogenase IvdG (EC:1.1.1.178) (from data) 0.62 SO0345 prpB methylisocitrate lyase (NCBI ptt file) 0.40 18

Not shown: 10 genomes with orthologs for PP_2214 only; 17 genomes with orthologs for PP_2334 only